Patent application number | Description | Published |
20110318752 | METHOD FOR IMPROVING THE YEILD OF A POLYPEPTIDE - The present invention relates to a method for improving protein yield. The method comprises modifying the value of a set of relevant protein features to fall within an optimal range or to become more close to an optimal value for one or more protein features in the eukaryotic host. | 12-29-2011 |
20120276567 | TALAROMYCES TRANSFORMANTS - The invention relates to a | 11-01-2012 |
20130040345 | HOST CELL CAPABLE OF PRODUCING ENZYMES USEFUL FOR DEGRADATION OF LIGNOCELLULOSIC MATERIAL - The invention relates to a host cell comprising at least four different heterologous polynucleotides chosen from the group of polynucleotides encoding cellulases, hemicellulases and pectinases, wherein the host cell is capable of producing the at least four different enzymes chosen from the group of cellulases, hemicellulases and pectinases, wherein the host cell is a filamentous fungus and is capable of secretion of the at least four different enzymes. | 02-14-2013 |
20130061354 | POLYPEPTIDE HAVING CELLOBIOHYDROLASE ACTIVITY AND USES THEREOF - The invention relates to a polypeptide comprising the amino acid sequence set out in SEQ ID NO: 2 or an amino acid sequence encoded by the nucleotide sequence of SEQ ID NO: 1, or a variant polypeptide or variant polynucleotide thereof, wherein the variant polypeptide has at least 93% sequence identity with the sequence set out in SEQ ID NO: 2 or the variant polynucleotide encodes a polypeptide that has at least 93% sequence identity with the sequence set out in SEQ ID NO: 2. The invention features the full length coding sequence of the novel gene as well as the amino acid sequence of the full-length functional polypeptide and functional equivalents of the gene or the amino acid sequence. The invention also relates to methods for using the polypeptide in industrial processes. Also included in the invention are cells transformed with a polynucleotide according to the invention suitable for producing these proteins. | 03-07-2013 |
20130095532 | POLYPEPTIDE HAVING ACETYL XYLAN ESTERASE ACTIVITY AND USES THEREOF - The invention relates to a polypeptide comprising the amino acid sequence set out in SEQ ID NO: 2 or an amino acid sequence encoded by the nucleotide sequence of SEQ ID NO: 1, or a variant polypeptide or variant polynucleotide thereof, wherein the variant polypeptide has at least 82% sequence identity with the sequence set out in SEQ ID NO: 2 or the variant polynucleotide encodes a polypeptide that has at least 82% sequence identity with the sequence set out in SEQ ID NO: 2. The invention features the full length coding sequence of the novel gene as well as the amino acid sequence of the full-length functional polypeptide and functional equivalents of the gene or the amino acid sequence. The invention also relates to methods for using the polypeptide in industrial processes. Also included in the invention are cells transformed with a polynucleotide according to the invention suitable for producing these proteins. | 04-18-2013 |
20130145501 | CARBOHYDRATE DEGRADING POLYPEPTIDE AND USES THEREOF - The invention relates to a polypeptide having carbohydrate material degrading activity which comprises the amino acid sequence set out in SEQ ID NO: 2 or an amino acid sequence encoded by the nucleotide sequence of SEQ ID NO: 1 or SEQ ID NO: 4, or a variant polypeptide or variant polynucleotide thereof, wherein the variant polypeptide has at least 96% sequence identity with the sequence set out in SEQ ID NO: 2 or the variant polynucleotide encodes a polypeptide that has at least 96% sequence identity with the sequence set out in SEQ ID NO: 2. The invention features the full length coding sequence of the novel gene as well as the amino acid sequence of the full-length functional protein and functional equivalents of the gene or the amino acid sequence. The invention also relates to methods for using the polypeptide in industrial processes. Also included in the invention are cells transformed with a polynucleotide according to the invention suitable for producing these proteins. | 06-06-2013 |
Patent application number | Description | Published |
20140106398 | VECTOR-HOST SYSTEM - The present invention relates to a host cell deficient in an essential gene, comprising a vector, said vector comprising at least said essential gene and an autonomous replication sequence, wherein the host cell is a filamentous fungal cell. The invention also relates to a host cell deficient in an essential gene, comprising a vector, said vector comprising at least said essential gene and an autonomous replication sequence, wherein the host cell comprises a recombinant polynucleotide construct comprising a polynucleotide encoding a biological compound of interest or a compound involved in the synthesis of a biological compound of interest. | 04-17-2014 |
20150020235 | RASAMSONIA TRANSFORMANTS - A method for carrying out recombination at a target locus in a | 01-15-2015 |
20150197760 | PROMOTERS FOR EXPRESSING A GENE IN A CELL - The present invention relates to isolated | 07-16-2015 |
20150329843 | HOST CELL CAPABLE OF PRODUCING ENZYMES USEFUL FOR DEGRADATION OF LIGNOCELLULOSIC MATERIAL - The invention relates to a host cell comprising at least four different heterologous polynucleotides chosen from the group of polynucleotides encoding cellulases, hemicellulases and pectinases, wherein the host cell is capable of producing the at least four different enzymes chosen from the group of cellulases, hemicellulases and pectinases, wherein the host cell is a filamentous fungus and is capable of secretion of the at least four different enzymes. This host cell can suitably be used for the production of an enzyme composition that can be used in a process for the saccharification of cellulosic material. | 11-19-2015 |
20150361408 | CARBOHYDRATE DEGRADING POLYPEPTIDE AND USES THEREOF - The invention relates to a polypeptide having hemicellulase activity. The invention features the full length coding sequence of the novel gene as well as the amino acid sequence of the full-length functional protein and functional equivalents of the gene or the amino acid sequence. The invention also relates to methods for using the polypeptide in industrial processes. Also included in the invention are cells transformed with a polynucleotide according to the invention suitable for producing these proteins. | 12-17-2015 |
Patent application number | Description | Published |
20130204964 | RETRIEVING AVAILABILITY INFORMATION FROM PUBLISHED CALENDARS - An application retrieves a published calendar from an online calendar application. The application formats the published calendar according to user status states such as “free” or “busy.” The application can also alternatively assign user status information from the published calendar to users status state levels such as “free,” “tentative,” “out of office,” “busy,” and “remotely available.” The application matches calendar owner information to a contact from a contact list of the application in order to link the formatted calendar to the contact. The application presents the linked calendar for scheduling | 08-08-2013 |
20130212252 | REPRESENTING REMOTELY AVAILABLE USERS THROUGH WORKING ELSEWHERE STATUS - An application provides a “working elsewhere” status for users working at a location other than their regular work location and still available for meetings, communication sessions, etc. The application determines a user location being other than regular work location and the user still being available through user selection, information from user associated application(s), and/or from a presence notification. The application adjusts the user status to a working elsewhere status and makes the new status available to other applications such as calendaring, communication applications, presence service(s), and comparable ones. Meetings may be scheduled, communication sessions facilitated if the working elsewhere status is sufficient/acceptable for other users. | 08-15-2013 |
Patent application number | Description | Published |
20140149886 | CALENDARING BETWEEN USER PROFILES - Calendar items can be scheduled with a joined group of user profiles. Scheduling calendar items can include, for each of the calendar items, sending a calendar item request to each of the user profiles in the group of user profiles. In response to the joining of a new user profile to the group, the new user profile can be automatically sent a calendar item request for each of one or more of the calendar items scheduled with the group of user profiles. Also, a first user profile can receive a request to share a calendar with a second user profile. The request can be received from the second user profile and can list one or more additional user profiles as recipients of the request. A representation of the request to share can include a control that can be selected to share the calendar with the additional user profile(s). | 05-29-2014 |
20140149896 | FOR-YOUR-INFORMATION EVENTS - A for-your-information event can be received in a computer system. The for-your-information event can include an event time field that indicates a scheduled time for the for-your-information event. The computer system may not automatically block the scheduled time of the for-your-information event on a calendar in response to receiving the for-your-information event. User input indicating that the for-your-information event is to be converted to a regular event can be received. In response to the user input, the computer system can convert the for-your-information event to a regular event. Converting the for-your information event can include automatically including the scheduled time of the for-your-information event as a scheduled time for the converted regular event. Also in response to the user input, the computer system can automatically block the scheduled time of the for-your-information event on the calendar. | 05-29-2014 |
20150193742 | CALENDARING BETWEEN USER PROFILES - Calendar items can be scheduled with a joined group of user profiles. Scheduling calendar items can include, for each of the calendar items, sending a calendar item request to each of the user profiles in the group of user profiles. In response to the joining of a new user profile to the group, the new user profile can be automatically sent a calendar item request for each of one or more of the calendar items scheduled with the group of user profiles. Also, a first user profile can receive a request to share a calendar with a second user profile. The request can be received from the second user profile and can list one or more additional user profiles as recipients of the request. A representation of the request to share can include a control that can be selected to share the calendar with the additional user profile(s). | 07-09-2015 |
Patent application number | Description | Published |
20080274488 | Covalent tethering of functional groups to proteins and substrates therefor - A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate and has at least two amino acid substitutions relative to the wild-type hydrolase. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein. | 11-06-2008 |
20090098627 | Method of immobilizing a protein or molecule via a mutant dehalogenase that is bound to an immobilized dehalogenase substrate and linked directly or indirectly to the protein or molecule - A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate and has at least two amino acid substitutions relative to the wild-type hydrolase. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein. | 04-16-2009 |
20110171673 | COVALENT TETHERING OF FUNCTIONAL GROUPS TO PROTEINS AND SUBSTRATES THEREFOR - A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate and has at least two amino acid substitutions relative to the wild-type hydrolase. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein. | 07-14-2011 |
20110201024 | COMPOSITIONS COMPRISING A DEHALOGENASE SUBSTRATE AND A FLUORESCENT LABEL AND METHODS OF USE - A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein. | 08-18-2011 |
20110207195 | METHOD OF IMMOBILIZING A PROTEIN OR MOLECULE VIA A MUTANT DEHALOGENASE THAT IS BOUND TO AN IMMOBILIZED DEHALOGENASE SUBSTRATE AND LINKED DIRECTLY OR INDIRECTLY TO THE PROTEIN OR MOLECULE - A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate and has at least two amino acid substitutions relative to the wild-type hydrolase. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein. | 08-25-2011 |
20120220013 | COVALENT TETHERING OF FUNCTIONAL GROUPS TO PROTEINS AND SUBSTRATES THEREFOR - A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate and has at least two amino acid substitutions relative to the wild-type hydrolase. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein. | 08-30-2012 |
20120252048 | COMPOSITIONS COMPRISING A DEHALOGENASE SUBSTRATE AND A CONTRAST AGENT AND METHODS OF USE - A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein. | 10-04-2012 |
20120258470 | COMPOSITIONS COMPRISING A DEHALOGENASE SUBSTRATE AND A RADIONUCLIDE AND METHODS OF USE - A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein. | 10-11-2012 |
20120330001 | METHOD OF IMMOBILIZING A PROTEIN OR MOLECULE VIA A MUTANT DEHALOGENASE THAT IS BOUND TO AN IMMOBILIZED DEHALOGENASE SUBSTRATE AND LINKED DIRECTLY OR INDIRECTLY TO THE PROTEIN OR MOLECULE - A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate and has at least two amino acid substitutions relative to the wild-type hydrolase. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein. | 12-27-2012 |
20130337539 | COVALENT TETHERING OF FUNCTIONAL GROUPS TO PROTEINS AND SUBSTRATES THEREFOR - A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate and has at least two amino acid substitutions relative to the wild-type hydrolase. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein. | 12-19-2013 |
20150125924 | COVALENT TETHERING OF FUNCTIONAL GROUPS TO PROTEINS AND SUBSTRATES THEREFOR - A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate and has at least two amino acid substitutions relative to the wild-type hydrolase. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein. | 05-07-2015 |
20150140587 | METHOD OF IMMOBILIZING A PROTEIN OR MOLECULE VIA A MUTANT DEHALOGENASE THAT IS BOUND TO AN IMMOBILIZED DEHALOGENASE SUBSTRATE AND LINKED DIRECTLY OR INDIRECTLY TO THE PROTEIN OR MOLECULE - A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate and has at least two amino acid substitutions relative to the wild-type hydrolase. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein. | 05-21-2015 |
20160031911 | COVALENT TETHERING OF FUNCTIONAL GROUPS TO PROTEINS - A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein. | 02-04-2016 |
Patent application number | Description | Published |
20110250264 | METHOD FOR FORMULATING LARGE DIAMETER SYNTHETIC MEMBRANE VESICLES - The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated. | 10-13-2011 |
20130177633 | METHOD FOR FORMULATING LARGE DIAMETER SYNTHETIC MEMBRANE VESICLES - The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated. | 07-11-2013 |
20130177634 | METHOD FOR FORMULATING LARGE DIAMETER SYNTHETIC MEMBRANE VESICLES - The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated. | 07-11-2013 |
20130177635 | METHOD FOR FORMULATING LARGE DIAMETER SYNTHETIC MEMBRANE VESICLES - The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated. | 07-11-2013 |
20130177636 | METHOD FOR FORMULATING LARGE DIAMETER SYNTHETIC MEMBRANE VESICLES - The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated. | 07-11-2013 |
20130177637 | METHOD FOR FORMULATING LARGE DIAMETER SYNTHETIC MEMBRANE VESICLES - The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated. | 07-11-2013 |
20130177638 | METHOD FOR FORMULATING LARGE DIAMETER SYNTHETIC MEMBRANE VESICLES - The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated. | 07-11-2013 |
20130183372 | METHOD FOR FORMULATING LARGE DIAMETER SYNTHETIC MEMBRANE VESICLES - The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated. | 07-18-2013 |
20130183373 | METHOD FOR FORMULATING LARGE DIAMETER SYNTHETIC MEMBRANE VESICLES - The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated. | 07-18-2013 |
20130183375 | METHOD FOR FORMULATING LARGE DIAMETER SYNTHETIC MEMBRANE VESICLES - The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated. | 07-18-2013 |
20130195965 | METHOD FOR FORMULATING LARGE DIAMETER SYNTHETIC MEMBRANE VESICLES - The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated. | 08-01-2013 |
20130306759 | METHOD FOR FORMULATING LARGE DIAMETER SYNTHETIC MEMBRANE VESICLES - The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated. | 11-21-2013 |
Patent application number | Description | Published |
20100160382 | ANTI-ACID PHARMACEUTICAL COMPOSITION IN POWDER FORM AND PROCESS FOR MAKING IT - An anti-acid pharmaceutical composition for the rapid and prolonged neutralization of gastric acidity with mucosa-protecting activity in powder form to prepare, by dispersion in water, a pharmaceutical solution or suspension for oral use characterized in that the composition includes sodium alginate; an anti-acid soluble agent or a combination of anti-acids; an inhibitor of proton pump; diluent and sweetening agents, wherein a) at least 30% of sodium alginate present in the formulation along with the total of the inhibitor of proton pump are homogeneously distributed over the surface of the total soluble anti-acid agent [or] of the combination of anti-acids of the composition; and b) the rest, about 70%, of sodium alginate present in the formulation contains a percentage of humidity of less than 2%. | 06-24-2010 |
20120294941 | PHARMACEUTICAL COMPOSITION WITH ANTI-OBESITY ACTIVITY COMPRISING A PREMIXTURE OF PURE ORLISTAT AND PREPARATION PROCESS - Pharmaceutical compositions with anti-obesity activity that act peripherally are provided, which comprise a premixture made up of pure orlistat as the active ingredient and other components that afford the premixture stability and suitable physical properties for simply preparing compositions for oral use with convenient dosage flexibility; and optionally necessary thickening, flavouring and colouring agents. A method for preparing said compositions is also provided. The orlistat content in the premixture is less than 20% of the total weight of the mass, preferably between 12 and 17%. | 11-22-2012 |
20140107108 | COMPOSITIONS COMPRISING ALPRAZOLAM FOR TREATING PRIMARY INSOMNIA AND INSOMNIA ASSOCIATED WITH ANXIETY STATES AND PROCESS FOR PREPARING THEM - Disclosed is a composition comprising alprazolam for treating primary insomnia and insomnia associated with anxiety states and the corresponding use and method comprising the administration of alprazolam sublingual tablets having a disintegration time lower than 30 seconds and having the alprazolam preferably in non-crystalline or partially crystalline form according to the X-ray diffraction crystallography expanded for the position delta 9-12.5 (2 theta), to a patient suffering from said disorder. There is also disclosed a method for preparing a composition according to the invention, where the alprazolam is solved in a pharmaceutical acceptable solvent and a binder, preferably polyvinylpyrrolidone, is incorporated to the solution. A pre-made mixture of part of the cross-linked carboxymethyl-cellulose and the rest of the ingredients of the composition is impregnated with the solution and is dried and grinded, and is added to the rest of the cross-linked carboxymethyl-cellulose and the flavoring additives, being then mixed and compressed. | 04-17-2014 |
20150072000 | METHOD FOR PRODUCING ENTERIC ALGINATE MICROCAPSULES VIA IONIC GELATION CONTAINING DICLOFENAC OR ONE OF THE SALTS THEREOF AND MULTIPARTICLED PHARMACEUTICAL COMPOSITION CONTAINING THEM - Method for producing enteric microcapsules without coating, containing diclofenac or one of the salts thereof with satisfactory anti-inflammatory activity and low gastric aggressiveness; and a pharmaceutical composition containing them. The method comprises a) preparing a mixture in water-ethanol with an alginate salt, adding diclofenac or one of the salts thereof previously diluted with a surfactant and sodium bicarbonate; b) adding the previous solution to a solution with a calcium salt; c) resuspending the microcapsules obtained and isolated in an aqueous solution of the alginate salt; and d) isolating, drying and sieving through 1000 and 250 micron meshes the microcapsules obtained; and selecting the fraction comprised between both meshes. The pharmaceutical composition can be an oral composition, tablets, chewable tablets, or a powder for suspension in water. | 03-12-2015 |
Patent application number | Description | Published |
20100085688 | GROUNDING CONNECTOR FOR AN ELECTRONIC DEVICE - A grounding connector for an electronic device having a first housing element and a second housing element comprising a ground clip, a cam surface and a follower. The ground clip is electrically coupled to a first housing element, and selectably electrically coupled with the second housing element. A cam surface is positioned on the first housing element and in proximity to the ground clip. The follower is slidably positionable on the second housing element, and has a first end that engages the cam surface and a second end that engages the ground clip. The ground clip is electrically coupled to a second housing element while the electronic device is in each of the collapsed orientation and the articulated orientation. Upon movement between the collapsed orientation and the articulated orientation, the cam surface directs the follower to electrically decouple the ground clip from the second housing element. | 04-08-2010 |
20120225622 | SEPARABLE MOBILE DEVICE HAVING A CONTROL MODULE AND A DOCKING STATION MODULE - The technology provides a mobile communication device having separable components, including a control module configured for only short-range wireless communication and a docking station module configured for both long-range wireless communication and short-range wireless communication. The control module includes a touch-sensitive display, a short-range wireless transceiver and a processor that electrically couples the touch-sensitive display and the short-range wireless transceiver. The docking station module includes a docking area that receives the control module, a docking short-range wireless transceiver configured to communicate with the control module, a long-range wireless transceiver that is configured to communicate with a. long-range network and a docking processor that electrically couples the docking short-range wireless transceiver and the long-range wireless transceiver. The technology provides a sleek light-weight control module having full functionality of the docking station module. | 09-06-2012 |
20120270596 | APPARATUS AND METHOD FOR CONTROLLING A CAMERA IN AN ELECTRONIC DEVICE - An apparatus and a method in an electronic device provide for controlling a camera, wherein the camera can selectively operate in a first focus mode and in a second focus mode. The first focus mode is initially selected. In response to detecting a state of the electronic device, the second focus mode is selected. The first focus mode can be an autofocus mode. The second focus mode can be an extended depth of field mode, wherein software processing is used to extend the focus range of the camera. The detected state of the electronic device can be a previous user selection, a low power mode, or a continued request for taking photographs following taking a photograph in the autofocus mode. | 10-25-2012 |
20120274576 | INPUT DEVICE WITH TACTILE FEEDBACK - An input device includes an electrical isolator disposed on a base, the electrical isolator comprising at least a first element extending away from the base. A first actuator is disposed on the base and on a first side of the first element and is configured to provide first tactile feedback. A second actuator is disposed on the base and on a second side of the first element and is configured to provide second tactile feedback. A touch sensor is disposed with the first actuator and the second actuator and is arranged to provide touch data such that input is provided based on the touch data. | 11-01-2012 |
20120287053 | MULTI-MODAL USER INPUT DEVICE - A user input device, a portable electronic device including the user input device, and an operating method therefor, manages multiple modes of the user input device based on detected force and direction of tilt. The user input device includes a base member with top surface. A sensor touchpad module is disposed above the top surface of the base member. A plurality of pressure sensors is disposed between the base member and the sensor touchpad module. A processor manages a set of user input modes based on whether at least one of a first set of signals associated with a first user input mode and a second set of signals associated with a second user input mode has been detected. | 11-15-2012 |
20120287587 | SURFACE MOUNTABLE NAVIGATION DEVICE WITH TACTILE RESPONSE - A surface mountable navigation device with tactile response includes a flexible coupling component and a navigation sensor. The flexible coupling component can be a flexible printed circuit having a first end and a second end. The flexible coupling component can be folded at least partially on itself so that the first end is above the second end. The first end of the flexible coupling component can be coupled to the navigation sensor. The second end of the flexible coupling component can be coupled to a circuit board of an electronic device. The second end can have a plurality of conductor pads adapted to electrically couple the navigation sensor to the circuit board. As the flexible coupling component can be folded onto itself, the navigation device requires less space within the interior of the electronic device. | 11-15-2012 |
20130027351 | OPTICAL NAVIGATION MODULES FOR MOBILE COMMUNICATION DEVICES - The disclosure provides a navigation assembly having a compact design that reduces a depth dimension in a z-direction or along a z-axis that is substantially perpendicular to a front face of a mobile communication device. The navigation assembly includes an optical lens unitarily formed with a cover, the cover having an upper surface that receives user inputs thereon and a lower surface that receives the optical lens. A sensor array is provided in optical communication with the optical lens and a coupling structure is provided to mechanically couple the optical lens and the sensor array. The cover overlays a gap formed between the navigation assembly and adjacent keys to prevent contaminants such as liquids, dust, lint, or the like, from entering an interior of the mobile communication device. The cover also includes a decorative ring that defines a tracking window and outlines a perimeter of the underlying sensor arrays. | 01-31-2013 |
20130100030 | KEYPAD APPARATUS HAVING PROXIMITY AND PRESSURE SENSING - Keypad apparatus and methods are described herein. An example keypad includes a dome-switch assembly having a dome aligned relative to a first trace pattern and a second trace pattern of a printed circuit board and a key aligned with the dome. The key is depressible between an initial position, an intermediate position and a depressed position, where the key is to deflect the dome to electrically couple the first and second trace patterns when the key is in the depressed position. A touch sensing film detects a touch on a keycap of the key when the key is in the initial position and a pressure sensing film detects a force on the keycap when the key is in the intermediate position. | 04-25-2013 |
20130116009 | UNIVERSAL INTEGRATED CIRCUIT CARD APPARATUS AND RELATED METHODS - UICCs are disclosed herein. An example UICC includes a body a body having a height between approximately 10.9 millimeters and 11.1 millimeters and a width between approximately 8.9 millimeters and 9.1 millimeters. | 05-09-2013 |
20130270349 | UICC APPARATUS AND RELATED METHODS - UICC apparatus and related methods are disclosed herein. An example UICC apparatus disclosed herein includes a contact pad having a plurality of electrical contacts positioned or oriented to define a plurality of electrical contact patterns. The plurality of electrical contact patterns defining at least a first electrical contact pattern to communicate with a first input device and a second electrical contact pattern to communicate with a second input device, where the first input device has a dimensional profile that is different than a dimensional profile of the second input device. | 10-17-2013 |
20130314377 | OPTICAL TOUCH SENSOR APPARATUS - Optical touch sensors are disclosed herein. An example optical touch sensor includes a plurality of optical transmitters arranged to emit light generally in a first direction and a plurality of optical receivers. At least one optical transmitter corresponds with each of the plurality of optical receivers. The sensor also includes an optical guide comprising a plurality of optical channels arranged in the first direction, where the optical guide provides a protective cover for the plurality of optical transmitters and the plurality of optical receivers. | 11-28-2013 |
20140076704 | KEYPAD APPARATUS FOR USE WITH ELECTRONIC DEVICES AND RELATED METHODS - A keypad apparatus and related methods are disclosed herein. An example keypad apparatus includes an electrical switch and a carrier composed of a plastic resin. The carrier has conductive traces printed thereon to couple the electrical switch to a circuit board via interference. | 03-20-2014 |
20150244116 | FORWARD AND BACKWARD COMPATIBLE 5 POLE AUDIO PLUG AND JACK SYSTE - A backward compatible five-contact audio plug and jack system that provides for connecting to five separate channels of an audio accessory including two speaker channels and two microphone channels. The audio plug includes an added smaller diameter ring contact positioned within a longitudinal position normally occupied by tip contact of a conventional 4-contact audio plug and specifically located within 5.1 mm of a tip of the five-contact audio plug. The jack contact for the tip contact of the plug and the jack contact for the added smaller diameter ring contact are within 4.75 mm of each other, preferably at a distance between 1.5 mm and 2.5 mmm. The smaller diameter ring contact has a maximum diameter that is smaller than a maximum diameter of the tip contact specified in ITU P.381 standard which is 3.05 mm. | 08-27-2015 |
Patent application number | Description | Published |
20120093680 | METHOD FOR OBTAINING COPPER POWDERS AND NANOPOWDERS FROM INDUSTRIAL ELECTROLYTES INCLUDING WASTE INDUSTRIAL ELECTROLYTES - The method for obtaining copper powders and nanopowders from industrial electrolytes including waste industrial electrolytes through electrochemical deposition of metallic copper on a cathode consists in using potentiostatic pulse electrolysis without the current direction change or with the current direction change, using the cathode potential value close to the plateau or on the plateau of the current voltage curve on which the plateau of the current potential range is from −0.2 V÷−1 V, and a moveable or static ultramicroelectrode or an array of ultramicroelectrodes made of gold, platinum or stainless steel wire or foil is used as a cathode, whereas metallic copper is used as an anode and the process is carried out at temperature from 18-60° C., and the electrolysis lasts from 0.005 to 60 s. Said method can be used to obtain nanopowders and powders characterised by particle structure and dimension repeatability and purity from 99%+ to 99.999% from waste industrial electrolytes and wastewaters from copper industry and electroplating plants without additional treatment. | 04-19-2012 |
20130204109 | Method and Apparatus for Non-Invasive Analyzing the Structure and Chemical Composition of Bone Tissue Eliminating the Influence of Surrounding Tissues - A method and apparatus for non-invasive analysing the structure and chemical composition of bone tissue eliminating the influence of surrounding tissues, is provided. The method consists in using a system of at least four electrodes ( | 08-08-2013 |
20140106293 | DEVICE AND METHOD FOR SECONDARY DENTAL CARIES DIAGNOSIS - A device for secondary caries detection characterized in that it contains a current generating block in its casing ( | 04-17-2014 |
20150160185 | METHOD FOR CONTROLLING ELECTRODES FOR BIO-IMPEDANCE MEASUREMENTS AND APPARATUS FOR BIO-IMPEDANCE MEASUREMENTS - Method for Controlling Electrodes for Bio-impedance Measurements and Apparatus for Bio-impedance Measurements There is provided a control circuit for electrodes in a bio-impedance measurement system, the bio-impedance measurement system comprising screening current injecting electrodes and measuring current injecting electrodes, the control circuit comprising: a current generator for connection to at least one screening current injecting electrode; and an measuring signal output configured to establish a measuring potential between the measuring current injecting electrodes, wherein the control circuit is configured such that the measuring potential is dependent on a measure of a potential difference resulting from the screening current. The control circuit uses the value of the potential resulting from the screening current to determine the potential difference between the measuring current injecting electrodes. In this way the flow of measuring current can be made smaller than the screening current and necessarily at a safe level. | 06-11-2015 |