Lebecque
Serge Lebecque, Civrieux D'Azerques FR
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20090285779 | INDUCTION OF APOPTOSIS IN TOLL-LIKE RECEPTOR EXPRESSING TUMOR CELLS - Some types of cancer cells express one or more Toll-like receptors (TLRs). These TLRs are therapeutic targets. The invention relates to methods for treating Toll-like receptor expressing cancers and tumor cells by selecting a TLR expressing tumor cell and contacting the cell with a therapeutically effective amount of a TLR ligand. The invention particularly relates to methods for treating TLR3 expressing cancers and tumor cells using TLR3 agonists. | 11-19-2009 |
Serge Lebecque, Civrieux D'Azergues FR
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20120045523 | COMBINATION OF A TLR3 LIGAND AND A CHEMOTHERAPY AGENT WHICH ACTS ON THE INTRINSIC "APOPTOSIS" PATHWAY IN THE TREATMENT OF CANCER - The present invention relates to a drug comprising separately or together (i) a TLR3 ligand and (ii) a chemotherapeutic agent that acts on the intrinsic apoptotic pathway, for simultaneous or sequential administration in the treatment of cancer, wherein the chemotherapeutic agent is selected from topoisomerase II inhibitors, platinum-derived alkylating agents and PI3 kinase inhibitors. | 02-23-2012 |
20140329261 | TREATMENT OF CANCER BY INHIBITION OF THE MYD88/ERK MAP KINASE INTERACTION - A method for selecting in vitro compounds is capable of potentiating the effect of a DNA damage inducing chemotherapy agent for the treatment of cancer, and includes selecting compounds inhibiting the interaction between MyD88 and ERK MAP KINASE. | 11-06-2014 |
Serge J.e. Lebecque, Civrieux D'Azergues FR
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20110033929 | USES OF ANTIBODIES TO MAMMALIAN DC LANGERHANS CELL ANTIGEN - The present invention relates to purified mammalian DC cell surface protein, designated Langerin, nucleic acids encoding Langerin, and antibodies which specifically bind Langerin. | 02-10-2011 |
Serge J.e. Lebecque, Civieux D'Azergue FR
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20110244513 | ISOLATED MAMMALIAN MEMBRANE PROTEIN GENES; RELATED REAGENTS - Nucleic acids encoding various lymphocyte cell proteins from mammalian, including primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided. | 10-06-2011 |
Serge J. E. Lebecque, Civrieux D'Azergues FR
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20090275735 | MONOCLONAL ANTIBODIES TO HUMAN CTLA-8 (IL-17A) - Human CTLA-8 protein, antibodies that specifically bind to human CTLA-8, and nucleic acids encoding human CTLA-8. Methods of using these molecules and diagnostic kits are also provided. | 11-05-2009 |