Patent application number | Description | Published |
20080200775 | Maneuver-based plethysmographic pulse variation detection system and method - The disclosed embodiments relate to a system and method for monitoring patient data. An exemplary method comprises obtaining plethysmographic pulse variation data that corresponds to a variation in a plethysmographic pulse of a patient, searching the plethysmographic pulse variation data for an indication of a reduction of venous return in response to a maneuver on or by the patient, and generating an output if the indication of the reduction of venous return is detected. | 08-21-2008 |
20080200819 | Orthostasis detection system and method - The disclosed embodiments relate to a system and method for monitoring patient data. An exemplary method comprises obtaining hemodynamic variation data that corresponds to a variation in intravascular hemodynamics of a patient, searching the hemodynamic variation data for an indication of orthostasis in response to the occurrence of a positional maneuver of or by the patient, and generating an output if the indication orthostasis is discovered. | 08-21-2008 |
20080287756 | Pulse oximetry relational alarm system for early recognition of instability and catastrophic occurrences - A relational pulse oximetry alarm system and method is presented for earlier identification of the occurrence of an adverse clinical event. The system includes a pulse oximeter based microprocessor alarm system which provides an alarm based on a relational conformation of a plurality of time series and further based on the recognition of specific dynamic patterns of interaction between a plurality of corresponding and related time series including the occurrence of pathophysiologic divergence of two or more time series outputs. The processor is programmed to compare a first time series to a second time series to produce a comparison result, to identify a relationship between the first time series and the second time series, to identify a relational threshold breach, and to output an alarm based on the relational threshold breach. The system can include an oximeter testing system for predicting the timeliness of the response of the alarm of a pulse oximeter to the occurrence of an adverse clinical event. | 11-20-2008 |
20080312166 | Reversal core pharmaceutical system and method - A medication delivery system is disclosed to mitigate or reverse the pharmacologic effect of a medication beyond the desired therapeutic window. The system provides sequential delivery of medications including a first agent which induces a physiologic change, a second agent for reversing the physiologic change, and a medication release delaying agent for delaying the release of the second agent so that, upon receipt of the medication delivery system into the body the first agent is released before the second agent so that the physiologic effect of the first agent is mitigated by the second agent. The system can be a pill with the first agent comprising an outer medication and the second agent an inner medication with the medication release delaying agent intermediate the outer medication and the inner medication. In an example, the first agent can comprise a sleep aid and the second agent an arousal agent. | 12-18-2008 |
20090281838 | MEDICAL FAILURE PATTERN SEARCH ENGINE - A patient safety search engine and alarm processor is programmed to repetitively search the electronic medical records of all patients in a hospital system to automatically provide early detection of patients with evolving pathophysiologic cascades, and in particular the cascades of evolving death, such as cascades of septic shock. The search engine also searches for a wide range of evolving pathophysiologic failures which are commonly fatal if detected too late. An alarm processor is provided which is programmed to provide an alarm upon the detection of a cascade or failure. The processor is further be programmed to provide an image of the cascade, and to determine, the severity of the cascade, and the time of onset of the cascade in relation to the timing and type of procedures and treatment and the increased cost associated with the cascade. Discretionary real-time system-wide searches for a wide range of clinical failure patterns or images within the hospital system may be performed using the disclosed patient safety search engine. | 11-12-2009 |
20090281839 | PATIENT SAFETY PROCESSOR - A processor-based system for analyzing physiologic data and medical care is provided wherein the patient data is analyzed to construct images that are representative of a patient's condition. The processor provides a self-modulating analysis, which is responsive to the occurrence of additional data items to increase the information contained in the images. Identifications of modes of physiologic failure by the analysis of the generated images provides for earlier recognition and intervention and improved protocolization of testing and treatment. | 11-12-2009 |
20100079292 | MICROPROCESSOR SYSTEM FOR THE ANALYSIS OF PHYSIOLOGIC AND FINANCIAL DATASETS - A medical alarm system for processing physiologic and laboratory data in hospitals and other environments is disclosed. The alarm system provides early detection of complex pathophysiologic cascades. The alarm system detects aggregated timed patterns of inflammatory indicators, metabolic, pulse, blood pressure, oxygen saturation, and/or ventilation trends to detect expanding cascade patterns characteristic of, for example, progressive sepsis. The system may include a processor programmed to convert at least the physiologic and laboratory data of a patient into a predetermined format favorable for searching. The system may also include a processor programmed to search the formatted data to detect the progressively expanding global patterns of abnormal data characteristic of evolving sepsis and/or septic shock. The alarm system may be configured to provide an early warning for healthcare workers when a pattern indicative of progression of a complex pathophysiologic cascade is detected. | 04-01-2010 |
20100174161 | SYSTEM AND METHOD FOR THE DETECTION OF PHYSIOLOGIC RESPONSE TO STIMULATION - The disclosed embodiments relate to a system and method for detecting a response of a patient to an external stimulus. An exemplary method comprises the acts of generating at least one time series of at least one physiologic parameter, detecting the external stimulus, detecting at least one response associated with the stimulus, the response comprising at least one of a pattern and a value, and outputting an indication of the response. | 07-08-2010 |
20100234705 | System and Method for Automatic Detection of a Plurality of SP02 Time Series Pattern Types - The disclosed embodiments relate to a patient monitor for evaluating a patient. The patient monitor may comprise a sensor that is adapted to detect a sound associated with breathing of the patient and to produce a first output indicative of the sound, an oximeter that is adapted to receive an input from the patient and to produce a second output indicative of oxygen saturation of blood of the patient, and a processor adapted to receive at least the first output and the second output and to correlate the first output with the second output. | 09-16-2010 |
20110015501 | MICROPROCESSOR SYSTEM FOR THE ANALYSIS OF PHYSIOLOGIC AND FINANCIAL DATASETS - A system and method for organization and analysis of complex and dynamically interactive time series is disclosed. One example comprises a processor based system for relational analysis of physiologic signals for providing early recognition of catastrophic and pathologic events such as pathophysiologic divergence. The processor is programmed to identify pathophysiologic divergence of at least one of first and second physiologic parameters in relationship to the other and to output an indication of the divergence. An object-based method of iterative relational processing waveform fragments in the time domain is described wherein each more complex waveform object inherits the characteristics of the waveform objects from which it is derived. The first physiologic parameter can be the amplitude and frequency of the variation in chest wall impedance or nasal pressure and the second parameter can be a measure or indication of the arterial oxygen saturation. | 01-20-2011 |
20110208539 | SYSTEM AND METHOD FOR AUTOMATIC DETECTION OF A PLURALITY OF SP02 TIME SERIES PATTERN TYPES - The disclosed embodiments relate to a patient monitor for evaluating a patient. The patient monitor may comprise a sensor that is adapted to detect a sound associated with breathing of the patient and to produce a first output indicative of the sound, an oximeter that is adapted to receive an input from the patient and to produce a second output indicative of oxygen saturation of blood of the patient, and a processor adapted to receive at least the first output and the second output and to correlate the first output with the second output. | 08-25-2011 |
20120302845 | SYSTEM AND METHOD FOR SPO2 INSTABILITY DETECTION AND QUANTIFICATION - The disclosed embodiments relate to a system and method for analyzing data. An exemplary method comprises the acts of receiving data corresponding to at least one time series, and computing a plurality of sequential instability index values of the data. An exemplary system comprises a source of data indicative of at least one time series of data, and a processor that is adapted to compute at least one of a plurality of sequential instability index values of the data. | 11-29-2012 |
20120330118 | CENTRALIZED HOSPITAL MONITORING SYSTEM FOR AUTOMATICALLY DETECTING UPPER AIRWAY INSTABILITY AND FOR PREVENTING AND ABORTING ADVERSE DRUG REACTIONS - A system and method for the automatic diagnosis of obstructive sleep apnea in a centralized hospital critical care monitoring system for the monitoring of a plurality of patients in at least one of a critical care, step down, and cardiac ward by telemetry. The system includes a central processor having a display, and a plurality of telemetry units for mounting with patients, each of the telemetry units has a plurality of sensors for connection with each patient, the telemetry unit is capable of the transmission of multiple signals derived from the sensors to the central processor, in one preferred embodiment the method comprising steps of programming the system to analyze the signals and to automatically identify the presence and severity of obstructive sleep apnea and to provide an indication of the identification. | 12-27-2012 |
20130060110 | SYSTEM AND METHOD FOR AUTOMATIC DETECTION OF A PLURALITY OF SPO2 TIME SERIES PATTERN TYPES - The disclosed embodiments relate to pulse oximetry. An exemplary pulse oximeter comprises a probe that is adapted to be attached to a body part of a patient to create a signal indicative of an oxygen saturation of blood of the patient, and a processor that is adapted to receive the signal produced by the probe, to calculate an SPO2 value based on the signal, to detect a plurality of pattern types of SPO2 indicative of pathophysiologic events, and to produce an output indicative of a detected one of the plurality of pattern types. | 03-07-2013 |
20130073311 | PATHOPHYSIOLOGIC STORM TRACKER - A method and device for providing information about a medical condition are described herein. The device can include a memory storage that contains information relating to correlations between data for physiological systems, the correlations being indicative of distress conditions of a patient. The device can also include a monitor that gathers information about the physiological systems of the patient, reads from the memory storage, and identifies a distress condition based on correlations between data for the physiological systems. Furthermore, the device can include a display processor that provides a visual display of correlations between the physiological systems as a storm spreading across visual depictions of the physiological systems in response to the identification of the distress condition providing a metaphorical, color weather map visualization of the dynamic progression, expansion and relational severity of the distress condition. | 03-21-2013 |
20130124221 | REAL-TIME TIME SERIES MATRIX PATHOPHYSIOLOGIC PATTERN PROCESSOR AND QUALITY ASSESSMENT METHOD - A device for providing information about a medical condition is described herein. A monitor gathers information about the physiological systems of the patient, reads from the memory storage, identifies time dimensioned dynamic patterns of the data, determines the severity of the patterns, identifies a distress condition based at least on a relative match between a the dynamic patterns of the data for a plurality of physiological systems, and calculates a real-time or near real-time sensitivity, specificity, therapeutic delay, and/or correlation metric. A display processor that provides a visual display of time dimensioned output of the severity of the dynamic patterns and a visual display of the sensitivity, specificity, therapeutic delay, and/or the correlation metric in real-time or near real-time. | 05-16-2013 |
20130131993 | ITERATIVE TIME SERIES MATRIX PATTERN ENHANCER PROCESSOR - A method and system for analyzing data about a physiological occurrence is described herein. The method includes executing a first software element to produce a result set with physiological data related to a set of patients. The method also includes detecting a physiological occurrence within the result set. Furthermore, the method includes generating a second software element to increase the accuracy of the first software element based on the physiological occurrence and the physiological data from the set of patients. | 05-23-2013 |
20130158375 | Alarm Processor for Detection of Adverse Hemodynamic Effects of Cardiac Arrhythmia - The disclosed embodiments relate to an apparatus and method for providing a warning. In one example, an apparatus includes a sensor, which is configured to be coupled to a body of a patient and to output a photoplethysmograph signal, which is indicative of pulse waveforms in the body. The apparatus also includes a processor, which is coupled to process the photoplethysmograph signal so as to identify sequential pulse waveforms in the signal, the processor detecting a cardiac arrhythmia based on identifying a shape feature of the pulse waveform occurring simultaneously with a change in rate or rhythm of the pulse waveforms or an electrocardiographic waveform, and to output a warning responsive to the simultaneous occurrence. | 06-20-2013 |
20130209068 | PATIENT SAFETY PROCESSOR - A processor-based system for analyzing physiologic data and medical care is provided wherein the patient data is analyzed to construct images that are representative of a patient's condition. The processor provides a self-modulating analysis, which is responsive to the occurrence of additional data items to increase the information contained in the images. Identifications of modes of physiologic failure by the analysis of the generated images provides for earlier recognition and intervention and improved protocolization of testing and treatment. | 08-15-2013 |
20130218600 | MEDICAL FAILURE PATTERN SEARCH ENGINE - A patient safety search engine and alarm processor is programmed to repetitively search the electronic medical records of all patients in a hospital system to automatically provide early detection of patients with evolving pathophysiologic cascades, and in particular the cascades of evolving death, such as cascades of septic shock. The search engine also searches for a wide range of evolving pathophysiologic failures which are commonly fatal if detected too late. An alarm processor is provided which is programmed to provide an alarm upon the detection of a cascade or failure. The processor is further be programmed to provide an image of the cascade, and to determine, the severity of the cascade, and the time of onset of the cascade in relation to the timing and type of procedures and treatment and the increased cost associated with the cascade. Discretionary real-time system-wide searches for a wide range of clinical failure patterns or images within the hospital system may be performed using the disclosed patient safety search engine. | 08-22-2013 |
20130268291 | PATIENT SAFETY PROCESSOR - A processor-based system for analyzing physiologic data and medical care is provided wherein the patient data is analyzed to construct images that are representative of a patient's condition. The processor provides a self-modulating analysis, which is responsive to the occurrence of additional data items to increase the information contained in the images. Identifications of modes of physiologic failure by the analysis of the generated images provides for earlier recognition and intervention and improved protocolization of testing and treatment. | 10-10-2013 |
20130290011 | PATIENT SAFETY PROCESSOR - A processor-based system for analyzing physiologic data and medical care is provided wherein the patient data is analyzed to construct images that are representative of a patient's condition. The processor provides a self-modulating analysis, which is responsive to the occurrence of additional data items to increase the information contained in the images. Identifications of modes of physiologic failure by the analysis of the generated images provides for earlier recognition and intervention and improved protocolization of testing and treatment. | 10-31-2013 |
20130338459 | System and Method for Automatic Detection of A Plurality of SPO2 Time Series Pattern Types - The disclosed embodiments relate to pulse oximetry. An exemplary pulse oximeter comprises a probe that is adapted to be attached to a body part of a patient to create a signal indicative of an oxygen saturation of blood of the patient, and a processor that is adapted to receive the signal produced by the probe, to calculate an SPO2 value based on the signal, to detect a plurality of pattern types of SPO2 indicative of pathophysiologic events, and to produce an output indicative of a detected one of the plurality of pattern types. | 12-19-2013 |
20140152673 | Patient Monitor for Generating Real-Time Relational Animations of Human Organs in Response to Physiologic Signals - A medical alarm system for processing medical time-series data of multiple physiologic signals in hospitals and other environments is disclosed. The alarm system generates physiologic animations in real-time. The physiologic animations are shaped as a schematic of the physiologic system being monitored. The physiologic system is comprised of multiple components corresponding to organs. The physiologic animation and organs move over time in response to the physiologic signals. | 06-05-2014 |
20140163897 | System and Method for Detecting a Baseline Gradient - The disclosed embodiments relate to a system and method for analyzing data. An exemplary method comprises the acts of receiving data corresponding to at least one time series, and computing a plurality of sequential instability index values of the data. An exemplary system comprises a source of data indicative of at least one time series of data, and a processor that is adapted to compute at least one of a plurality of sequential instability index values of the data. | 06-12-2014 |
20140176538 | System for Converting Biologic Particle Density Data into Motion Images - A system for converting biologic particle density data into a motion image of at least one clinical condition such as sepsis, wherein the system comprises a processor programmed to detect a plurality of perturbations of the biologic particle densities associated with the clinical condition, detect or determine features of the perturbations, and detect or determine patterns of the perturbations. The processor can also be programmed to generate an image of the clinical condition comprised of time image components comprising a two dimensional user-facing map, wherein time extends along an axis away from the user facing map such that the map may be scrolled forward or backward over time to view different two dimensional images of the clinical condition. | 06-26-2014 |
20140176558 | PATIENT STORM TRACKER AND VISUALIZATION PROCESSOR - A patient monitoring system is described herein. In one example, the patient monitoring system comprises at least one processor programmed to generate an image which displays a patient condition as color weather radar on a map. In some examples, at least one monitored condition is positioned on the map so that the weather image expands, develops or moves over the condition. | 06-26-2014 |
20140180722 | Time Lapsable Motion Image Responsive to Features of Pathophysiologic Perturbations - A patient monitoring system for generating dynamic relational visualizations of at least one clinical condition comprising a processor programmed to detect a plurality of perturbations of biologic particle densities associated with the clinical condition and to detect features of the perturbations and to generate cells of images responsive to the features. The system generates at least one motion image comprising the cells. New cells and the cells change, for example in color or position in response to changes in a medical condition. | 06-26-2014 |
20140241601 | System for Analysis and Imaging Using Perturbation Feature Quanta - A medical device comprises a processor programmed to detect and analyze perturbations of biologic particle densities and convert a set of features of the perturbations into a discreet set of quanta in relation to a phenotypic, baseline or expected range of the perturbation features. The processor is also programmed to convert at least a second set of features from a second perturbation into a second discreet set of quanta and to compare the first set of set of quanta with the second set of quanta and to render motion images of the perturbations and quanta. The quanta may be defined at least in part by the pattern of perturbations or a clinical condition. | 08-28-2014 |
20140241602 | System for Presentation of Sequential Blood Laboratory Measurements to Image Recognition Systems - A system for presenting data to an image recognition system is described herein, wherein the system comprises at least one processor programmed to receive time specific medical data comprising a plurality of lab values, particle concentrations, and/or physical measurements of blood of a patient collected at a series of points in time and convert the biologic particle densities into image components, images or sequences of images. The processor is programmed to generate the image components, images or sequences of images on a map or display and to present the map or display to an image recognition system. | 08-28-2014 |
20140241603 | SYSTEM FOR GENERATING MOTION IMAGES OF FEATURE SETS OF PERTURBATIONS OF BIOLOGIC PARTICLE DENSITIES - A patient monitoring system detects perturbations and detects or determines features of the perturbations and generates image cells responsive to the perturbations, organelles within the cells responsive to the features, and clinical regions responsive to the cells, and visualizations responsive to the clinical regions. The system also generates time-lapsable motion images comprising the cells which change over time in response to changes in the features or the detection of new perturbations. The system may convert the features into quanta defined at least in part by the clinical condition and may generate image components, such as pixels or groups of pixels, responsive to the quanta. Motion images may be generated from the image components. | 08-28-2014 |
20140244184 | System and Method for Biologic Particle Density Path Projection - A processing method is disclosed for projecting one or more biologic particle density paths and for defining at least one retesting time for a specific biologic particle density of a patient. The processor is programmed to process laboratory data from the patient or from a data repository. The processor identifies a pattern of a plurality of biologic particle densities and based on at least the pattern identifies a medical condition and calculates a potential worst case pattern or trajectory of the laboratory test value over time based on the pattern and/or the identified medical condition. The system may calculate or identify the retesting time based on at least the minimum change of the parameter which would have actionable clinical relevance. | 08-28-2014 |
20140244303 | Parallel Human Time Matrix Image of Causation - A patient monitoring system comprising at least one processor programmed to generate a force binary comprised of at least a first object comprising a force, wherein the force comprises a biologic particle density or a biologic particle density perturbation. In some examples, the force binary also comprises a second object comprised of at least one biologic particle density perturbation induced by the force. In some embodiments, the at least one processor can also generate a plurality of force binaries, link the force binaries to each other to generate a force cascade comprised of linked force binaries, and identify the force cascade. | 08-28-2014 |
20140244304 | System and Method for Generating Quaternary Images of Biologic Force Propagation and Recovery - A patient monitoring system is disclosed comprising at least one processor programmed to process medical data derived from a patient or medical records repository and to compose interconnected cascades of physiological occurrences by linking or grouping four fundamental elements which comprise; a perturbation, at least one perturbation force which is capable of inducing and may have induced the perturbation, a recovery, and at least one recovery force which is capable of inducing and may have induced the perturbation. The four elements are linked or grouped by the processor to generate a quaternary which may be characterized as solved or unsolved. | 08-28-2014 |
20140288849 | System for Generating a Dynamic Spectral Signature of an Evolving Biologic Distortion - A medical diagnostic system for quantifying at least one perturbation of a concentration of at least one constituent of blood of a patient over time is described herein. In some examples, the system includes a processor programmed to analyze data comprising the concentration, the concentration having a reference range and define a range of perturbed concentration values which is outside the reference range. The processor can also be programmed to divide the range of perturbed concentration values into sequential sub-ranges comprising at least a first sub-range of concentration values and a second sub-range of concentration values, the second sub-range being further away from the reference range than the first sub-range and assign quanta to each sub-range such that the number of quanta assigned to a sub range far away from the reference range is greater than the number of quanta assigned to a sub-range close to the reference range. | 09-25-2014 |
20140288953 | Sepsis Time Matrix Processor - A relational time pattern based real-time sepsis detection and tracking system is disclosed. The system comprises a processor programmed to receive an input of multiple data streams over time comprising a plurality of sequential physiologic and laboratory values, analyze the relational time patterns of the data streams, and output a warning of a possible sepsis condition based on the analysis. The processor may be programmed to generate a time matrix of the data and further an animated three dimensional matrix of sepsis which changes shape in relation to the severity of sepsis. | 09-25-2014 |
20140358033 | Luer Receiving Air Evacuated Blood Collector - An improved luer lock receiving septum having a configuration which provides rapid and tight resealing and yet allows penetration of the septum by the luer tip with a low penetration force. The elongated septum includes an upper portion of enlarged diameter having a target surface, a central slit, and a central, lower septum extension projecting about the slit below the upper portion and into a housing so that following luer insertion there is provided sufficient room for both the laterally displaced extension of the septum, the luer taper, and the housing to be received into a conventional luer lock connector. The septum is further preferably configured to minimize or eliminate the negative pressure deflection normally associated with the withdrawal of the large diameter luer cannula from an enclosed fluid filled lumen or chamber, by substantially isolating the lumen or chamber from the septum material displacement resultant from luer insertion. In an exemplary embodiment, the luer receiving septum is provided at a port of an air evacuated blood collector. | 12-04-2014 |
20150045686 | Monitoring System for Identifying an End-Exhalation Carbon Dioxide Value of Enhanced Clinical Utility - A medical monitoring system for identifying an end-exhalation carbon dioxide value of enhanced clinical utility is described herein. The medical monitoring system can include a capnometer for generating an output corresponding to a time-series of exhaled carbon dioxide values from a patient during an exhalation and a processor programmed to analyze the exhalation. In some examples, the processor can also be programmed to identify a peak carbon dioxide value at an end of the exhalation, determine if the peak carbon dioxide value may have been higher if the exhalation had been prolonged, and provide an output responsive to said determination. | 02-12-2015 |
20150066533 | Method for automatically detecting sepsis and displaying dynamic sepsis images in a hospital system - A system for automatically detecting and displaying sepsis images in a hospital system is described herein. In some examples, the system can include receiving data related to a plurality of physiological parameters from a patient over time, and identifying and organizing patterns of perturbations of the data. The system can also include analyzing the perturbations to identify known relational physiologic patterns and detecting a pattern of sepsis, the pattern being comprised of a plurality of perturbations and/or relational physiologic patterns. Furthermore, the system can include organizing and synthesizing the plurality of relational physiologic patterns into a set of sepsis images, which as an aggregate whole make up an image representation of the complex and dynamic state of sepsis, and displaying the sepsis images. The images can be color motion images of cascades which display the severities of individual perturbations and relational physiologic patterns along the cascade pattern. | 03-05-2015 |