Lai, US
Arthur Lai, Minnetonka, MN US
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20090292340 | Regulatory Compliant Transmission of Medical Data Employing a Patient Implantable Medical Device and a Generic Network Access Device - Various embodiments concern a method which may include communicating medical information between a PIMD and an interface module via a first channel in compliance with a predetermined medical information regulatory standard, preventing access to the PIMD via the interface module other than through the first channel, detecting a communication protocol used by an available generic network access device, selecting a communication protocol rule set from a plurality of communication protocol rule sets to effect communication between the interface device and an available generic network access device of a plurality of generic network access devices, and transferring at least some of the medical information to the remote network via a second channel established between the interface module and the available generic network access device using the selected communication protocol rule set. | 11-26-2009 |
20120124210 | Regulatory Compliant Transmission of Medical Data Employing a Patient Implantable Medical Device and a Generic Network Access Device - Various embodiments concern a method which may include communicating medical information between a PIMD and an interface module via a first channel in compliance with a predetermined medical information regulatory standard, preventing access to the PIMD via the interface module other than through the first channel, detecting a communication protocol used by an available generic network access device, selecting a communication protocol rule set from a plurality of communication protocol rule sets to effect communication between the interface device and an available generic network access device of a plurality of generic network access devices, and transferring at least some of the medical information to the remote network via a second channel established between the interface module and the available generic network access device using the selected communication protocol rule set. | 05-17-2012 |
20130007210 | Regulatory Compliant Transmission of Medical Data Employing a Patient Implantable Medical Device and a Generic Network Access Device - Various embodiments concern a method which may include communicating medical information between a PIMD and an interface module via a first channel in compliance with a predetermined medical information regulatory standard, preventing access to the PIMD via the interface module other than through the first channel, detecting a communication protocol used by an available generic network access device, selecting a communication protocol rule set from a plurality of communication protocol rule sets to effect communication between the interface device and an available generic network access device of a plurality of generic network access devices, and transferring at least some of the medical information to the remote network via a second channel established between the interface module and the available generic network access device using the selected communication protocol rule set. | 01-03-2013 |
20130254348 | REGULATORY COMPLIANT TRANSMISSION OF MEDICAL DATA EMPLOYING A PATIENT IMPLANTABLE MEDICAL DEVICE AND A GENERIC NETWORK ACCESS DEVICE - An interface device for facilitating transfer of medical information between a patient implantable medical device (PIMD) and a remote network server via public network infrastructure is disclosed, the interface device using any of a plurality of generic network access devices having disparate communication protocols. First communication circuitry is configured to receive medical information from a patient implantable medical device (PIMD), and second communication circuitry configured to effect communication with the first communication circuitry and a generic network access device. A processor is coupled the first communication circuitry and the second communication circuitry. The processor is configured to control transmission of the medical information to the generic network access device and condition the medical device data in compliance with a predetermined medical information regulatory standard governing the PIMD. A method is also disclosed. | 09-26-2013 |
20150073251 | MEDICAL DEVICE WITH AUTOMATIC START-UP UPON CONTACT TO PATIENT TISSUE - Methods and devices for monitoring and/or treating patients comprise a switch to automatically start-up the device when the device contacts tissue. By automatically starting up the device, the device may be installed without the clinician and/or user turning on the device, such that the device can be easy to use. In many embodiments, the device comprises startup circuitry with very low current and/or power consumption, for example less than 100 pA. The startup circuitry can detect tissue contact and turn on circuitry that is used to monitor or treat the patient. | 03-12-2015 |
Bo-Kuai Lai, Woodridge, IL US
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20130264680 | NANOLAMINATES OF Al2O3/TiO2 WITH GIANT DIELECTRIC CONSTANT LOW-LEAKAGE-LOW LOSS-EXTENDED FREQUENCY OPERATION FOR NEW-GENERATION NANOELECTRONICS AND ENERGY STORAGE DEVICES - The invention relates generally to a nanolaminate structure involving Al | 10-10-2013 |
Bo Shiun Lai, Chicago, IL US
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20130053427 | Conjugate constructs, delivery, and use for treatment of disease - Pharmaceutical formulations of antisense peptide-conjugated phosphorodiamidate morpholino olgomers and methods of use for treatment of apicomplexan infections are disclosed. The invention is particularly directed to treatment of | 02-28-2013 |
Chia Yin Kevin Lai, Portland, OR US
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20130339689 | LATER STAGE READ PORT REDUCTION - In some implementations, a register file has a plurality of read ports for providing data to a micro-operation during execution of the micro-operation. For example, the micro-operation may utilize at least two data sources, with at least one first data source being utilized at least one pipeline stage earlier than at least one second data source. A number of register file read ports may be allocated for executing the micro-operation. A bypass calculation is performed during a first pipeline stage to detect whether the at least one second data source is available from a bypass network. During a subsequent second pipeline stage, when the at least one second data source is detected to be available from the bypass network, the number of the read ports allocated to the micro-operation may be reduced. | 12-19-2013 |
20140195790 | PROCESSOR WITH SECOND JUMP EXECUTION UNIT FOR BRANCH MISPREDICTION - A secondary jump execution unit (JEU) is incorporated in a micro-processor to operate concurrently with a primary JEU, enabling the execution of simultaneous branch operations with possible detection of multiple branch mispredicts. When branch operations are executed on both JEUs in a same instruction cycle, mispredict processing for the secondary JEU is skidded into the primary JEU's dispatch pipeline such that the branch processing for the secondary JEU occurs after processing of the branch for the primary JEU and while the primary JEU is not processing a branch. Moreover, in cases when a nuke command is also received from a reorder buffer of the processor, the branch processing for the secondary JEU is further delayed to accommodate processing of the nuke on the primary JEU. Further embodiments support the promotion of the secondary JEU to have access to the mispredict mechanisms of the primary JEU in certain circumstances. | 07-10-2014 |
Chien-Hung Lai US
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20120100944 | ELECTRICAL CONTROL BELT CONTINUOUSLY VARIABLE TRANSMISSION SYSTEM - An electrical control belt continuously variable transmission system controls a movable driving half-pulley or movable driven half-pulley initiatively, by changing a driving interval between the movable driving half-pulley and a fixed driving half-pulley or a driven interval between the movable driven half-pulley and a fixed driven half-pulley, respectively, depending on different statuses, in order to adjust a velocity ratio. By manipulating the movable driving half-pulley or the movable driven half-pulley, the system may further form a driving gap between the movable driving half-pulley and a transmission belt or a driven gap between the movable driven half-pulley and the transmission belt, such that the power is cut off. Clamping the movable driving half-pulley or the movable driven half-pulley to the transmission belt may restore the outputting of the power. | 04-26-2012 |
Chih-Hung Lai, Cerritos, CA US
Patent application number | Description | Published |
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20130274283 | PREMATURE-TERMINATION-CODONS READTHROUGH COMPOUNDS - Premature termination codons readthrough compounds, composition thereof, and methods of making and using the same are provided. | 10-17-2013 |
Ching-Juh Lai, Bethesda, MD US
Patent application number | Description | Published |
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20100247549 | MONOCLONAL ANTIBODIES AGAINST DENGUE AND OTHER VIRUSES WITH DELETION IN FC REGION - The present invention relates to a variant of a parent polypeptide comprising an Fc region, which variant binds an Fc gamma receptor (FcγR) with lower affinity than the parent polypeptide and comprises a deletion of at least one amino acid in about position 100 to about position 150 in the Fc region and related nucleic acids, vectors, host cells and methods of producing the variant and methods for preventing or treating a disorder in a mammal. | 09-30-2010 |
20110008256 | MONOCLONAL ANTIBODIES THAT BIND OR NEUTRALIZE DENGUE VIRUS - The present invention relates to monoclonal antibodies that bind or neutralize dengue type 1, 2, 3, and/or 4 virus. The invention provides such antibodies, fragments of such antibodies retaining dengue virus-binding ability, fully human or humanized antibodies retaining dengue virus-binding ability, and pharmaceutical compositions including such antibodies. The invention further provides for isolated nucleic acids encoding the antibodies of the invention and host cells transformed therewith. Additionally, the invention provides for prophylactic, therapeutic, and diagnostic methods employing the antibodies and nucleic acids of the invention. | 01-13-2011 |
20110033462 | HUMANIZED MONOCLONAL ANTIBODIES THAT SPECIFICALLY BIND AND/OR NEUTRALIZE JAPANESE ENCEPHALITIS VIRUS (JEV) AND THEIR USE - Disclosed herein are isolated humanized monoclonal antibodies that specifically bind Japanese encephalitis virus (JEV) with a binding affinity of about 1.0 nM or less. Nucleic acids encoding these antibodies, expression vectors including these nucleic acid molecules, and isolated host cells that express the nucleic acid molecules are also disclosed. Methods of treating, preventing, and/or ameliorating JEV infection in a subject with JEV also are disclosed. Additionally, the antibodies can be used to detect JEV in a sample, and methods of diagnosing JEV infection, or confirming a diagnosis of JEV infection in a subject, are disclosed herein that utilize these antibodies. | 02-10-2011 |
20130089543 | MONOCLONAL ANTIBODIES THAT BIND OR NEUTRALIZE DENGUE VIRUS - The present invention relates to monoclonal antibodies that bind or neutralize dengue type 1, 2, 3, and/or 4 virus. The invention provides such antibodies, fragments of such antibodies retaining dengue virus-binding ability, fully human or humanized antibodies retaining dengue virus-binding ability, and pharmaceutical compositions including such antibodies. The invention further provides for isolated nucleic acids encoding the antibodies of the invention and host cells transformed therewith. Additionally, the invention provides for prophylactic, therapeutic, and diagnostic methods employing the antibodies and nucleic acids of the invention. | 04-11-2013 |
20130295090 | HUMANIZED MONOCLONAL ANTIBODIES THAT SPECIFICALLY BIND AND/OR NEUTRALIZE JAPANESE ENCEPHALITIS VIRUS (JEV) AND THEIR USE - Disclosed herein are isolated humanized monoclonal antibodies that specifically bind Japanese encephalitis virus (JEV) with a binding affinity of about 1.0 nM or less. Nucleic acids encoding these antibodies, expression vectors including these nucleic acid molecules, and isolated host cells that express the nucleic acid molecules are also disclosed. Methods of treating, preventing, and/or ameliorating JEV infection in a subject with JEV also are disclosed. Additionally, the antibodies can be used to detect JEV in a sample, and methods of diagnosing JEV infection, or confirming a diagnosis of JEV infection in a subject, are disclosed herein that utilize these antibodies. | 11-07-2013 |
20130344058 | MONOCLONAL ANTIBODIES AGAINST DENGUE AND OTHER VIRUSES WITH DELETION IN FC REGION - The present invention relates to a variant of a parent polypeptide comprising an Fc region, which variant binds an Fc gamma receptor (FcγR) with lower affinity than the parent polypeptide and comprises a deletion of at least one amino acid in about position 100 to about position 150 in the Fc region and related nucleic acids, vectors, host cells and methods of producing the variant and methods for preventing or treating a disorder in a mammal. | 12-26-2013 |
20150064214 | DEVELOPMENT OF MUTATIONS USEFUL FOR ATTENUATING DENGUE VIRUSES AND CHIMERIC DENGUE VIRUSES - A menu of mutations was developed that is useful in fine-tuning the attenuation and growth characteristics of dengue virus vaccines. | 03-05-2015 |
Choung Lai, Doylestown, PA US
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20110159421 | Production of Toner for Use in Printing Applications - The present invention provides a process for producing a colored toner comprising the steps of: providing a polymer composition comprising at least one polymer wherein the at least one polymer has a softening temperature from about 30° C. to about 160° C.; and a colorant; forming an aqueous mineral suspension of at least one multivalent metal phosphate by contacting a water-soluble salt of the multivalent metal with an aqueous solution comprising: a water-soluble phosphate salt; and at least one crystal growth inhibitor which controls the growth of the at least one multivalent metal phosphate, wherein the pH of the aqueous mineral suspension is from 5.5 to 14; and forming a dispersion of the polymer composition by adding the polymer composition to the aqueous mineral suspension under agitation to form a solid portion comprising dispersed particles of the polymer composition, wherein the temperature of the aqueous mineral suspension during the dispersing step is at least about 70° C. | 06-30-2011 |
20130045441 | INK TONER PARTICLES WITH CONTROLLED SURFACE MORPHOLOGY - The present invention provides a process for producing a colored toner having a textured surface, the process includes forming a polymer composition of at least one polymer and a colorant, where the at least one polymer has a softening temperature from about 60° C. to about 160° C.; forming an aqueous mineral suspension of at least one multivalent metal phosphate; forming a dispersion by combining the polymer composition and the aqueous mineral suspension under agitation to form a solid portion comprising dispersed particles of the polymer composition; heating the dispersion to a temperature above a glass transition temperature (Tg) of the polymer composition and increasing the pH to above 7.0; cooling the dispersion including the dispersed particles of the polymer composition to a temperature of from about 1° C. to about 89° C.; and recovering the particles. | 02-21-2013 |
Chun-Hsiang Lai, Durham, NC US
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20120071417 | METHODS OF INHIBITING CANCER CELL GROWTH WITH HDAC INHIBITORS AND METHODS OF SCREENING FOR HDAC10 INHIBITORS - Methods of inhibiting cancer cell growth using HDAC10 inhibitors are provided. Methods of treating cancer in a subject using HDAC10 inhibitors are also provided. In certain embodiments, at least one second inhibitor selected from an autophagy inhibitor, an AMPK inhibitor, and methyl pyruvate is also used in the methods. Dose packs comprising HDAC10 inhibitors and at least one second inhibitor are provided. Methods of identifying HDAC10 inhibitors are also provided. | 03-22-2012 |
Chun Kit Lai, Sunrise, FL US
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20120019421 | MOBILE WIRELESS DEVICE WITH MULTI-BAND LOOP ANTENNA WITH ARMS DEFINING A SLOTTED OPENING AND RELATED METHODS - A mobile wireless communications device may include a housing, a printed circuit board (PCB) carried by the housing. The device may also include an antenna coupled to wireless transceiver circuitry carried by the PCB. The antenna may include first and second feed legs extending upwardly from the PCB, a loop conductor spaced above the PCB and having a gap therein defining first and second ends, and a first conductor arm spaced above the PCB and extending between the first feed leg and the first end. The antenna may further include a second conductor arm spaced above the PCB and having a proximal portion between the second feed leg and the second end, and having a distal portion extending outwardly from the second feed leg. The first conductor arm and the proximal portion may define a slotted opening into an interior of the loop conductor. | 01-26-2012 |
20120032857 | MOBILE WIRELESS DEVICE WITH MULTI-BAND LOOP ANTENNA AND RELATED METHODS - A mobile wireless communications device may include a portable housing, a printed circuit board (PCB) carried by the portable housing, and wireless transceiver circuitry carried by the PCB. The mobile wireless communications device also may include an antenna coupled to the wireless transceiver circuitry. The antenna may include a loop conductor, a first conductor body coupled to the loop conductor and extending into the interior thereof to define a first slotted opening with adjacent portions of the loop conductor, and a second conductor body coupled to the loop conductor and extending into the interior thereof to define a second slotted opening with adjacent portions of the loop conductor. The antenna may further include a conductor arm coupled to the loop conductor and extending outwardly therefrom. The first and second conductor bodies may be spaced apart to define a third slotted opening therebetween. | 02-09-2012 |
20120032863 | MOBILE WIRELESS DEVICE WITH ENLARGED WIDTH PORTION MULTI-BAND LOOP ANTENNA AND RELATED METHODS - A mobile wireless communications device may include a portable housing, a printed circuit board (PCB) carried by the portable housing, and wireless transceiver circuitry carried by the PCB. The mobile wireless communications device also may include an antenna coupled to the wireless transceiver circuitry. The antenna may include a loop conductor, a first conductor body coupled to the loop conductor and extending into the interior thereof to define a first slotted opening with adjacent portions of the loop conductor, and a second conductor body coupled to the loop conductor and extending into the interior thereof to define a second slotted opening with adjacent portions of the loop conductor. The first and second conductor bodies may be spaced apart to define a third slotted opening therebetween. The first slotted opening may have an enlarged width portion adjacent the first conductive body. | 02-09-2012 |
Chun Kit Lai, Grand Blanc, MI US
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20090195477 | STACKED PATCH ANTENNAS - According to various exemplary embodiments, an antenna assembly generally includes one or more antennas, such as a single multi-frequency antenna, first and second stacked patch antennas, etc. The antenna assembly may be operable for receiving signals having different frequencies (e.g., a frequency associated with a satellite digital audio radio service (SDARS), a frequency associated with a global positioning system (GPS), etc.). The antenna assembly may generally include at least one antenna (e.g., a single multi-frequency antenna, first and second stacked patch antennas, etc.) having at least one feed point and tuned to at least one of a first frequency and a second frequency that is different than the first frequency. A low noise amplifier may be in communication with the at least one feed point for amplifying signals having the first frequency and signals having the second received from a signal output. A single communication link may be used for communicating an output signal of the antenna assembly. | 08-06-2009 |
Chunqiu Lai, Libertyville, IL US
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20110015172 | PYRROLOPYRAZINE INHIBITORS OF KINASES - The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, | 01-20-2011 |
20110257152 | PYRROLOPYRIDINE INHIBITORS OF KINASES - The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, | 10-20-2011 |
20130023523 | PYRIDAZINO[4,5-D]PYRIMIDIN-5(6H)-ONE INHIBITORS OF KINASES - The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, | 01-24-2013 |
20130102590 | PYRIDOPYRIMIDINONE INHIBITORS OF KINASES - The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, | 04-25-2013 |
20130225589 | PYRIDOPYRIMIDINONE INHIBITORS OF KINASES - The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, | 08-29-2013 |
20140275011 | PYRIDINE CDK9 KINASE INHIBITORS - Disclosed are compound of Formula (Ia), | 09-18-2014 |
20140275153 | CDK9 KINASE INHIBITORS - Disclosed are compound of Formula (Ia), | 09-18-2014 |
20140296220 | PYRIDAZINO[4,5-D]PYRIMIDIN-5(6H)-ONE INHIBITORS OF KINASES - The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, | 10-02-2014 |
20140357616 | PYRROLOPYRIDINE INHIBITORS OF KINASES - The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, | 12-04-2014 |
Chunqui Lai, Libertyville, IL US
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20130018045 | New Chemical Entities To Be Used For Wee1 Inhibition For The Treatment Of Cancer - The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, | 01-17-2013 |
Derhsing Lai, Yardley, PA US
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20080197027 | Novel Bioassay System Using a Nanoparticle - The invention is directed to a method for detecting a substance of interest using a nanoparticle containing a first substance and a matrix containing a second substance and detecting the radio signal emitted as a result of complex formation between the first and second substance as well as systems and kits using said method. | 08-21-2008 |
20080299082 | Novel recombinant T4 phage particle containing HIV, H. pylori or cancer antigens and uses thereof - The invention is directed to a novel recombinant T4 phage particle expressing a HOC and/or SOC | 12-04-2008 |
Ernest Lai, Honolulu, HI US
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20130116762 | ORAL SURGERY RECOVERY MASK - One example embodiment includes an oral surgery recovery mask for cooling an area of a user's face. The oral surgery recovery mask includes a bladder receptacle. The bladder receptacle includes a first layer and a second layer at least partially secured to the first layer. The oral surgery recovery mask also includes a cooling liquid, where the cooling fluid is configured to be inserted into the bladder receptacle. The oral surgery recovery mask also includes a securing device, where the securing device is configured to hold the oral surgery recovery mask in place relative to the user. | 05-09-2013 |
Frank Lai, Nashua, NH US
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20090296722 | Modular power line repeater and system - A data router or data switch connected to a medium and having private addresses bounded to a specific subsegment of and address range, and a user-selectable number of data repeaters also connected to the medium in a sequence of overlapping address ranges, in which a data repeater communicates upstream with a prior data repeater (or if it is the first repeater, the data router) and provides a data path to subsequent data repeaters over a different subsegments of that range by address translation, permitting extension of the usable range of the resulting network without the need for data-blocking filters on the medium, and without interference generated by the repeaters. | 12-03-2009 |
George Ying-Dean Lai, Carmel, IN US
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20080230155 | PROCESS AND METHOD TO INCREASE THE HARDNESS OF Fe-Cr-C WELD OVERLAY ALLOY - A method of preparing a mechanical component with an Fe—Cr—C hardfacing weld overlay alloy for improving the resistance of the mechanical component to abrasion, erosion or erosion/corrosion for use in very abrasive, erosion or erosive/corrosive environments by significantly increasing the hardness of the weld overlay is disclosed. To improve the resistance to abrasion, erosion or corrosion, a weld overlay of a Fe—Cr—C hardfacing alloy is applied onto the surface of a metallic component, such as tubes, pipes, or vessels. Welding and cladding methods including gas-metal-arc welding (GMAW), gas-tungsten-arc welding (GTAW), and laser cladding may be utilized. Then, the component is heat-treated at elevated temperatures for a sufficient time, resulting in additional hardening and thus further increasing the weld overlay's resistance to abrasion, erosion, or erosion/corrosion. | 09-25-2008 |
Harry Lai, Oveland Park, KS US
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20100076924 | SYSTEM AND METHOD OF MANAGING SOFTWARE PRODUCT-LINE CUSTOMIZATIONS - A method of managing application service provider product line variations is disclosed. The method includes receiving a client customization request, creating a configuration managed file tailored to the client customization request, binding the configuration managed file to at least one customizable resource, and deploying the customizable resource to a data store. The customizable resource is instantiated after disposition at the data store. | 03-25-2010 |
Hau-Wah Lai US
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20100090824 | Miniature and Multi-Band RF Coil Design - A near field apparatus comprises a Radio Frequency (RF) coil including at least one of a shorting bridge from a first point to a second point along an electrical path of the RF coil and/or a discontinuity in the electrical path of the RF coil. | 04-15-2010 |
Huafang Lai, Chandler, AZ US
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20120329994 | Production of a Monoclonal Antibody Therapeutic Against West Nile Virus in Plants - The present invention describes the plant-based production of a therapeutic antibody against West Nile Virus. | 12-27-2012 |
Hung Chi Lai, Fishers, IN US
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20110150209 | Full duplex telephone system employing automatic level control for improved digital signal processing of audio signals - Audio processing systems, such as full duplex digital telephone systems, are provided in which analog automatic level control (ALC) circuitry is employed to automatically control and stabilize the microphone output audio signal levels to a constant level for optimal digital signal processing. For example, an audio communication device ( | 06-23-2011 |
Jack W. Lai, Lake Elmo, MN US
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20110151199 | NEEDLE COATING AND IN-LINE CURING OF A COATED WORKPIECE - A method for coating a work piece with resin including applying a controlled volume of liquid resin to the work piece with an applicator and allowing consecutive streams of resin to meld together to form a self leveling surface. The resin can be actively or passively cured. The work piece can be planar or cylindrical. | 06-23-2011 |
20130113919 | HIGH RESOLUTION AUTOFOCUS INSPECTION SYSTEM - An inspection device comprises a camera assembly including an objective lens that captures and collimates light associated with an object being inspected, an image forming lens that forms an image of the object based on the collimated light, and a camera that renders the image. The camera assembly defines a focal point distance from the objective lens that defines a focal point of the camera assembly. The inspection device comprises an optical sensor positioned to detect an actual distance between the objective lens and the object, an actuator that controls positioning of the objective lens to control the actual distance between the objective lens and the object, and a control unit that receives signals from the optical sensor indicative of the actual distance. Control signals from the control unit can control the actuator to adjust the actual distance such that the actual distance substantially equals the focal point distance. | 05-09-2013 |
20130243972 | NEEDLE COATING AND IN-LINE CURING OF A COATED WORKPIECE - A method for coating a work piece with resin including applying a controlled volume of liquid resin to the work piece with an applicator and allowing consecutive streams of resin to meld together to form a self leveling surface. The resin can be actively or passively cured. The work piece can be planar or cylindrical. | 09-19-2013 |
20140240720 | LINEWIDTH MEASUREMENT SYSTEM - A method includes passing an interrogating light beam through a Fourier transform lens and onto the surface of a material to form a Fraunhofer diffraction pattern of one or more surface features of the material. An image of the diffraction pattern is processed to determine the dimensions of the feature. | 08-28-2014 |
20140362371 | SENSOR FOR MEASURING SURFACE NON-UNIFORMITY - A method includes forming a two-dimensional interrogating beam on a selected sample region of a surface; collecting light transmitted through or reflected from the sample region with an array of lenses to form a sample array of focus spots; imaging the sample array of focus spots through an imaging lens on a sensor; and comparing an image of the sample array of focus spots to a reference array of focus spots to determine a level of non-uniformity in the sample region. | 12-11-2014 |
James Chyl Lai, Saint Paul, MN US
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20090095338 | SOLAR POWER SOURCE - A solar power source includes a solar panel and a magnetic capacitor. The solar panel receives solar energy, and the magnetic capacitor stores energy and provides electricity. The solar panel has a first side facing the sun, and the magnetic capacitor is attached to a second side of the solar panel. The magnetic capacitor has high valued storage capacitance to handle the charge generated by the solar panel, and has a barrier to leakage current, so that storage time is increased. The solar power source is applicable for many applications and has low energy transport costs. The solar power source may have a higher number of re-charging cycles compared to batteries, and may be partially charged or discharged without a reduction in charge capacity. Two methods of manufacturing the solar power source are also provided. | 04-16-2009 |
Jiann-Shiun Lai US
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20120282260 | ANTI-HERPES SIMPLEX VIRUS ANTIBODIES AND METHODS OF USE THEREOF - The invention provides antibodies and polypeptides that specifically bind to the glycoprotein D of herpes simplex virus (HSV) and use of the antibodies and polypeptides for treating or diagnosing HSV infections. | 11-08-2012 |
Jian Ping Lai, Wallingford, PA US
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20130045518 | VARIANT SUCROSE TRANSPORTER POLYPEPTIDES THAT ENABLE FASTER SUCROSE UTILIZATION IN BACTERIA - Variant sucrose transporter polypeptides that enable faster sucrose utilization in bacteria are described. Additionally, variant or recombinant bacteria comprising these variant sucrose transporter polypeptides, and methods of utilizing the bacteria to produce products such as glycerol and glycerol-derived products are provided. | 02-21-2013 |
20130045519 | RECOMBINANT BACTERIA HAVING IMPROVED SUCROSE UTILIZATION - Recombinant bacteria having an improved ability to utilize sucrose are provided. These recombinant bacteria have nucleotide sequences encoding sucrose utilization polypeptides integrated into their genome between the yihP gene or its homolog and the yihO gene or its homolog. Additionally, methods of utilizing the recombinant bacteria to produce products such as glycerol and glycerol-derived products are provided. | 02-21-2013 |
20140093927 | Variant Sucrose Transporter Polypeptides That Enable Faster Sucrose Utilization In Bacteria - Variant sucrose transporter polypeptides that enable faster sucrose utilization in bacteria are described. Additionally, variant or recombinant bacteria comprising these variant sucrose transporter polypeptides, and methods of utilizing the bacteria to produce products such as glycerol and glycerol-derived products are provided. | 04-03-2014 |
Jim Lai, Santa Monica, CA US
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20130257031 | Interlocking Foam Book - Present invention relates to a foam book design for children of early ages, where cutout manipulative pieces from the foam pages allow for playing in a puzzle-like fashion; the foam pages are collected together in an interlocking manner and can be looped around the rings or disk-shaped objects along the cutout side holes on each foam page. | 10-03-2013 |
John Lai, Fulton, MD US
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20100080553 | AUTOMATIC LASER SHUTDOWN AND RECOVERY IN RESPONSE TO A LINK BREAK - A communication system may include a first control circuit to detect a break on a first optical link; a first optical source to supply a first optical signal on a second optical link in response to detecting the break on the first optical link, the first optical signal propagating in a first direction on the second optical link; a second control circuit to detect a presence of the first optical signal on the second optical link, and output a control signal in response to detecting the presence of the first optical signal; and a second optical source to supply a second optical signal on the second optical link, the second optical signal propagating in a second direction opposite the first direction, where the Raman pump is disabled in response to the control signal. | 04-01-2010 |
John Ck Lai, Leesburg, VA US
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20110053866 | PHARMACEUTICAL COMPOSITIONS - The present invention provides for a pharmaceutical composition that includes tetrabenazine and a release-retarding agent; and a method of treating a hyperkinetic movement disorder (e.g., Huntington's disease, chorea associated with Huntington's disease, hemiballismus, senile chorea, tic disorders, tardive dyskinesia, myoclonus, dystonia and/or Tourette's syndrome). The method includes administering an effective amount of the pharmaceutical composition, for a period of time effective to treat the hyperkinetic movement disorder. | 03-03-2011 |
20120208773 | PHARMACEUTICAL COMPOSITIONS WITH TETRABENAZINE - The present invention provides for a pharmaceutical composition that includes tetrabenazine and a release-retarding agent; and a method of treating a hyperkinetic movement disorder (e.g., Huntington's disease, chorea associated with Huntington's disease, hemiballismus, senile chorea, tic disorders, tardive dyskinesia, myoclonus, dystonia and/or Tourette's syndrome). The method includes administering an effective amount of the pharmaceutical composition, for a period of time effective to treat the hyperkinetic movement disorder. | 08-16-2012 |
20140030249 | Pharmaceutical Compositions - The present invention provides for a pharmaceutical composition that includes tetrabenazine and a release-retarding agent; and a method of treating a hyperkinetic movement disorder (e.g., Huntington's disease, chorea associated with Huntington's disease, hemiballismus, senile chorea, tic disorders, tardive dyskinesia, myoclonus, dystonia and/or Tourette's syndrome). The method includes administering an effective amount of the pharmaceutical composition, for a period of time effective to treat the hyperkinetic movement disorder. | 01-30-2014 |
Joseph Lai, San Pedro, CA US
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20130045632 | User-Friendly No-Metal Shell USB male Connector - This present invention is for a new user-friendly, thin, slim, no-metal shell USB male connector that is able to be inserted into a standard USB female receptacle in either orientation. | 02-21-2013 |
Ken Ming Lai, San Francisco, CA US
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20120198657 | Pivot Sliding Hinge - A telescoping adjustable pivot sliding hinge system, for mounting a door with at least a portion of the side edge of the door projecting into the opening when the door is in an open position, is disclosed. An upper mounting plate is mounted onto the door's top edge and is fastened to the door's interior side. First and second guide tracks are installed onto the header of the door opening. The upper mounting plate includes a pair of guide members that are operatively moveably engaged respectively with the first and second guide tracks. A lower mounting plate is mounted on a lower horizontal surface of the door opening, and includes a lower guide track and a telescoping adjustable pivot arm that is horizontally and rotationally captured at a proximal end thereof by the lower mounting plate. The lower mounting plate can be adjusted in relation to the base plate, and can be locked permanently with the said base plate by two machine screws and two nuts. The pivot arm's distal end is attached onto the door's bottom edge. A lower guide member, which is tucked into a guide shield, is fixed onto the door's bottom edge, and is operatively movably engaged with the lower guide track. | 08-09-2012 |
Kent Lai, Salt Lake City, UT US
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20110251236 | GALACTOKINASE INHIBITORS - Therapeutic agents for treatment of Galactosemia and disorders thereof, and other enzyme related disorders thereof are identified. The compounds inhibit galactokinase (GALK) and other kinase activity and are identified by a high throughput screening assay. | 10-13-2011 |
20140288100 | GALACTOKINASE INHIBITORS FOR THE TREATMENT AND PREVENTION OF ASSOCIATED DISEASES AND DISORDERS - Disclosed are inhibitors of human galactokinase of formula (1) that are useful in treating or preventing a galactokinase mediated disease or disorder, e.g., galactosemia. Also disclosed are a composition comprising a pharmaceutically acceptable carrier and at least one inhibitor of the invention, and a method of treating or preventing such disease or disorder in a mammal. Formula (I) | 09-25-2014 |
Konrad K. Lai, Vancouver, OR US
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20110153960 | TRANSACTIONAL MEMORY IN OUT-OF-ORDER PROCESSORS WITH XABORT HAVING IMMEDIATE ARGUMENT - Methods, systems, and apparatuses to provide an XABORT in a transactional memory access system are described. In one embodiment, the stored value is a context value indicating the context in which a transactional memory execution was aborted. A fallback handler may use the context value to perform a series of operations particular to the context in which the abort occurred. | 06-23-2011 |
20110153992 | METHODS AND APPARATUS TO MANAGE OBJECT LOCKS - Example methods and apparatus to manage object locks are disclosed. A disclosed example method includes receiving an object lock request from a processor, the lock request associated with object lock code to lock an object, and generating object lock-bypass code based on a type of the processor, the object lock-bypass code to execute in a managed runtime in response to receiving the object lock request. The example method also includes identifying a type of instruction set architecture (ISA) associated with the processor, invoking a checkpoint instruction for the processor based on the identified ISA, suspending the object lock code from executing and executing target code when the object is uncontended, and allowing the object lock code to execute when the object is contended. | 06-23-2011 |
20110161639 | Event counter checkpointing and restoring - A method of one aspect may include storing an event count of an event counter that counts events that occur during execution within a logic device. The method may further include restoring the event counter to the stored event count after the event counter has counted additional events. Other methods are also disclosed. Apparatus, systems, and machine-readable medium having software are also disclosed. | 06-30-2011 |
20120030518 | LAST BRANCH RECORD INDICATORS FOR TRANSACTIONAL MEMORY - In one embodiment, a processor includes an execution unit and at least one last branch record (LBR) register to store address information of a branch taken during program execution. This register may further store a transaction indicator to indicate whether the branch was taken during a transactional memory (TM) transaction. This register may further store an abort indicator to indicate whether the branch was caused by a transaction abort. Other embodiments are described and claimed. | 02-02-2012 |
20120227045 | METHOD, APPARATUS, AND SYSTEM FOR SPECULATIVE EXECUTION EVENT COUNTER CHECKPOINTING AND RESTORING - An apparatus, method, and system are described herein for providing programmable control of performance/event counters. An event counter is programmable to track different events, as well as to be checkpointed when speculative code regions are encountered. So when a speculative code region is aborted, the event counter is able to be restored to it pre-speculation value. Moreover, the difference between a cumulative event count of committed and uncommitted execution and the committed execution, represents an event count/contribution for uncommitted execution. From information on the uncommitted execution, hardware/software may be tuned to enhance future execution to avoid wasted execution cycles. | 09-06-2012 |
20130205119 | INSTRUCTION AND LOGIC TO TEST TRANSACTIONAL EXECUTION STATUS - Novel instructions, logic, methods and apparatus are disclosed to test transactional execution status. Embodiments include decoding a first instruction to start a transactional region. Responsive to the first instruction, a checkpoint for a set of architecture state registers is generated and memory accesses from a processing element in the transactional region associated with the first instruction are tracked. A second instruction to detect transactional execution of the transactional region is then decoded. An operation is executed, responsive to decoding the second instruction, to determine if an execution context of the second instruction is within the transactional region. Then responsive to the second instruction, a first flag is updated. In some embodiments, a register may optionally be updated and/or a second flag may optionally be updated responsive to the second instruction. | 08-08-2013 |
20140059333 | METHOD, APPARATUS, AND SYSTEM FOR SPECULATIVE ABORT CONTROL MECHANISMS - An apparatus and method is described herein for providing robust speculative code section abort control mechanisms. Hardware is able to track speculative code region abort events, conditions, and/or scenarios, such as an explicit abort instruction, a data conflict, a speculative timer expiration, a disallowed instruction attribute or type, etc. And hardware, firmware, software, or a combination thereof makes an abort determination based on the tracked abort events. As an example, hardware may make an initial abort determination based on one or more predefined events or choose to pass the event information up to a firmware or software handler to make such an abort determination. Upon determining an abort of a speculative code region is to be performed, hardware, firmware, software, or a combination thereof performs the abort, which may include following a fallback path specified by hardware or software. And to enable testing of such a fallback path, in one implementation, hardware provides software a mechanism to always abort speculative code regions. | 02-27-2014 |
20140258695 | Last Branch Record Indicators For Transactional Memory - In one embodiment, a processor includes an execution unit and at least one last branch record (LBR) register to store address information of a branch taken during program execution. This register may further store a transaction indicator to indicate whether the branch was taken during a transactional memory (TM) transaction. This register may further store an abort indicator to indicate whether the branch was caused by a transaction abort. Other embodiments are described and claimed. | 09-11-2014 |
20140379996 | METHOD, APPARATUS, AND SYSTEM FOR TRANSACTIONAL SPECULATION CONTROL INSTRUCTIONS - An apparatus and method is described herein for providing speculative escape instructions. Specifically, an explicit non-transactional load operation is described herein. During execution of a speculative code region (e.g. a transaction or critical section) loads are normally tracked in a read set. However, a programmer or compiler may utilize the explicit non-transactional read to load from a memory address into a destination register, while not adding the read/load to the transactional read set. Similarly, a non-transactional store is also provided. Here, a transactional store is performed and not added to a write set during speculative code execution. And the store may be immediately globally visible and/or persistent (even after an abort of the speculative code region). In other words, speculative escape operations are provided to ‘escape’ a speculative code region to perform non-transactional memory accesses without causing the speculative code region to abort or fail. | 12-25-2014 |
20150032998 | METHOD, APPARATUS, AND SYSTEM FOR TRANSACTIONAL SPECULATION CONTROL INSTRUCTIONS - An apparatus and method is described herein for providing speculation control instructions. An xAcquire and xRelease instruction are provided to define a critical section. In one embodiment, the xAcquire instruction includes a lock instruction with an elision prefix and the xRelease instruction includes a lock release instruction with an elision prefix. As a result, a processor is able to elide locks and transactionally execute a critical section defined in software by xAcquire and xRelease. But by adding only prefix hints, legacy processor are able to execute the same code by just ignoring the hints and executing the critical section traditionally with locks to guarantee mutual exclusion. Moreover, xBegin and xEnd are similarly provided for in an Instruction Set Architecture (ISA) to define a transactional code region. In addition, other control speculation instructions, such as xAbort to enable explicit abort of a critical or transactional code section and xTest to test a state of speculative execution is also provided in the ISA. | 01-29-2015 |
20150089286 | EVENT COUNTER CHECKPOINTING AND RESTORING - Event counter checkpointing and restoring is disclosed. In one implementation, a processor includes a first event counter to count events that occur during execution within the processor, event counter checkpoint logic, communicably coupled with the first event counter, to store, prior to a transactional execution of the processor, a value of the first event counter, a second event counter to count events prior to and during the transactional execution, wherein the second event counter is to increment without resetting after the transactional execution is aborted, event count restore logic to restore the first event counter to the stored value after the transactional execution is aborted, and tuning logic to determine, in response to aborting of the transactional execution, a number of the events that occurred during the transactional execution based on the stored value of the first event counter and a value of the second event counter. | 03-26-2015 |
Kuo-Tsai Griffin Lai, Rincon, GA US
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20090074685 | POLYAMIDE AND EMOLLIENT COMPOSITIONS, PRODUCTS MADE THEREFROM, AND METHODS OF MAKING AND USING SUCH COMPOSITIONS AND PRODUCTS - Formulations comprising a polyamide and an emollient, wherein the emollient comprises at least one selected from the group consisting of hydrocarbons with more than 8 carbons that may be linear or branched, and saturated or unsaturated; esters, such as benzoate esters, simple esters, or bulky esters; glycerol or glycerol condensate (mono-, di- or tri-); polyglycerol or polyglycerol condensate; guerbet ester; vegetable oils; and mixtures of silicone oils with any of the above emollients. Formulations may be any of cosmetic formulations, personal care product formulations, and all combinations thereof. Products comprising said formulations, and methods of making and using said formulations and products. | 03-19-2009 |
Kuo-Tsai Griffin Lai, Allentown, PA US
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20130065998 | Silicone Containing Compositions and Uses Thereof - Hydrogen, methyl, acetyl or butyl capped Polyether modified Silicone (PES) containing compositions are disclosed. The PES containing compositions can be used as defoamers or deaerators in coating compositions and, in particular, for airless sprayed compositions. | 03-14-2013 |
Laijun Lai, Newington, CT US
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20110200562 | Chimeric Cytokine of IL-7 and Beta Chain of HGF and Methods of Use - The present invention relates to a single-chain or chimeric polypeptide comprising a cytokine and a growth factor linked by at least one amino acid residue, and wherein the chimeric polypeptide enhances the proliferation and/or differentiation of hematopoietic precursor cells. In particular the invention relates to, a chimeric polypeptide comprising the beta-chain of hepatocyte growth factor, and IL-7 linked by at least one amino acid, and wherein the chimeric polypeptide demonstrates pre-pro-B proliferation and growth stimulating activity. | 08-18-2011 |
Lilin Lai, Decatur, GA US
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20120076820 | CD40L VACCINES, COMPOSITIONS, AND METHODS RELATED THERETO - The disclosure relates to vaccinating a subject against a viral infection, compositions, and methods related thereto. In certain embodiments, the disclosure relates to the use of CD40L expressed on viral like particle as an adjuvant, in combination with a viral antigen, to vaccinate a subject. | 03-29-2012 |
20130078276 | VECTORS EXPRESSING HIV ANTIGENS AND GM-CSF AND RELATED METHODS OF GENERATING AN IMMUNE RESPONSE - The disclosure provides vectors encoding one or more HIV antigens and GM-CSF. Also provided are methods of inducing an immune response in a subject, methods of treating a subject having HIV, and methods of manufacturing a medicament for inducing an immune response that require the use of these vectors and vaccine inserts. | 03-28-2013 |
Lou Lu Lai, Gurnee, IL US
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20080223151 | Static Torque Tester - A device and a method for measuring and indicating the static torque of a tapered roller bearing under varying axially applied loads. The device includes a base having a surface for supporting the cone of a tapered roller bearing, a fixture for engaging the cup of the tapered roller bearing when it is located on the base supporting surface. The fixture is mounted for linear movement with the cup relative to the cone to apply a static load to the cup. A variable static load applying mechanism such as an air cylinder is operatively connected to the fixture. A thrust applying frame which supports a thrust bearing connects the air cylinder and the fixture to uniformly transfer axial loads to the tapered roller bearing being tested. An indicating torque wrench is used to rotate the fixture and the engaged cup of the tapered roller bearing relative to the cone of the bearing under variable axial loads to determine and indicate the torque required. A lineal movement indicator is connected to the fixture to measure and indicate axial linear movement of the fixture and the engaged cup of the tapered roller bearing relative to the cone under various loads. | 09-18-2008 |
Mark Lai, Phoenix, AZ US
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20090133404 | SYSTEMS AND METHODS FOR COOLING GAS TURBINE ENGINE TRANSITION LINERS - A gas turbine engine assembly includes a combustor configured to combust an air-fuel mixture to produce combustion gases in a first direction; a transition liner coupled to the combustor and adapted to receive the combustion gases from the combustor and to redirect the combustion gases in a second direction; and a turbine coupled to the transition liner and adapted to receive the combustion gases from the transition liner. The transition liner has a plurality of effusion holes that include a first group that extend at least partially in a tangential direction. | 05-28-2009 |
Ming-Chih Lai US
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20120229124 | FIXING STRUCTURE FOR SIGNAL WIRES OF A RESOLVER - A fixing structure for signal wires of a resolver is disposable on an end face of a stator of the resolver. The fixing structure includes a circuit board, a fixing section disposed on the circuit board for connecting the circuit board to the end face of the stator, a connection terminal seat disposed on the circuit board, multiple connection sections formed through the circuit board in the form of holes, and multiple bridge circuits respectively arranged between the corresponding connection sections and the connection terminal seat for bridging the corresponding connection sections and the connection terminal seat. | 09-13-2012 |
Peng Lai, Union City, CA US
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20120262167 | ACCELERATED MULTISPECTRAL DATA MAGNETIC RESONANCE IMAGING SYSTEM AND METHOD - A method for processing magnetic resonance imaging data includes accessing the magnetic resonance imaging data, the data including a plurality of magnetic resonance data sets each collected at different excitation frequencies and defining reconstructable images representative of sections of a single image of a subject. Each magnetic resonance data set includes sampled data for sampled phase encoding points but is missing data for unsampled phase encoding points. The method further includes determining the missing data of at least one of the magnetic resonance data sets using a correlation between the sampled data for the respective magnetic resonance data set and sampled data from at least one other magnetic resonance data set within a spectral window encompassing at least the respective magnetic resonance data set and the at least one other magnetic resonance data set. | 10-18-2012 |
Peter Lai, Tallahassee, FL US
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20100178115 | Systems and Methods for Securing Foundation Members in a Substrate - Systems and methods are provided for establishing and securing a foundation in a substrate. For example, in one embodiment, a pump conveys a first fluid (e.g., water) through a pile member to produce an elongate opening in a substrate, which allows the pile member to be advanced into the substrate. After the pile member has been advanced into the elongate opening in the substrate, a second fluid (e.g., fluidized concrete) is conveyed out of openings on the side (and the bottom) of the pile member to substantially secure the pile member in the elongate opening defined in the substrate. | 07-15-2010 |
20130325367 | DETECTION OF STATIC TIP RESISTANCE OF A PILE - Systems and methods are provided for dynamically determining a static tip resistance of a dynamically-loaded component having a tip. One example method comprises receiving gauge data from one or more gauges associated with the component proximate the tip. The gauge data may represent measurements related to one or more impacts on the component. The example method may further comprise determining measured data and estimated data corresponding to the one or more impacts on the component based at least in part on the gauge data. Furthermore, the method may comprise performing an inversion to select the estimated data having the least amount of difference in comparison to the measured data. The method may also comprise determining the static tip resistance based at least in part on the selected estimated data. | 12-05-2013 |
Peter P. Lai, Rochester, MN US
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20120124425 | Method and Apparatus Useful In Manufacturing Test Case Operations - The incorporation of a simulation mode into existing manufacturing code test cases that communicate with a service processor. While in simulation mode, the test cases are able to run independently of system hardware or network connection. Test case code paths are exercised through the modification of simulated output, without change to the original code. | 05-17-2012 |
Po-Shen Lai US
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20110283055 | Exclusive-Option Chips and Methods with All-Options-Active Test Mode - A multi-interface integrated circuit in which, during the chip's lifetime in use, only one interface is active at a time. However, special test logic powers up all of the on-chip interface modules at once, so that a complete test cycle can be performed. All of the interfaces are exercised in one test program. Since some pads are inactive in some interface modes, mask bits are used to select which pads are monitored during which test cycles. | 11-17-2011 |
Qianxi Lai, Vista, CA US
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20120121933 | HYBRID COMPOSITE EMISSIVE CONSTRUCT AND LIGHT-EMITTING DEVICES USING THE SAME - Emissive constructs having three emissive layers, each having the same fluorescent host are described. At least one of the layers further includes a phosphorescent dopant. Light-emitting devices including these emissive constructs are also described. | 05-17-2012 |
20120223635 | POROUS FILMS FOR USE IN LIGHT-EMITTING DEVICES - Some porous films, such as organic non-polymeric porous films, may be useful for light outcoupling to increase light-emitting device efficiency. They may also be used for light scattering in other devices and for other applications related to the transfer of light. | 09-06-2012 |
20130140534 | Light-Emitting Devices Comprising Nanostructures - Light-emitting devices are described herein. | 06-06-2013 |
20130146856 | COMPOUNDS FOR USE IN LIGHT-EMITTING DEVICES - Compounds including optionally substituted Ring Systems 1-4 may be used as host in light-emitting devices. | 06-13-2013 |
20130153871 | TOP-EMITTING WHITE ORGANIC LIGHT-EMITTING DIODES HAVING IMPROVED EFFICIENCY AND STABILITY - Treatment for Cancer Using A Preparation containing a combination of one or more Natural or Synthetic or a Combination of Natural and Synthetic Boswellic Acids and one or more Natural or Synthetic or a Combination of Natural and Synthetic Cytokinins such as Kinetin, Kinetin Riboside and other Cytokinins and (the Preparation) could also contain one or more Natural or Synthetic or a Combination of Natural and Synthetic plant growth hormones such as Auxins in any percentage Ratio and could Optionally include Pharmaceutically Suitable Radioactive Agent (Radio Therapy) in any percentage ratio as a “Stand Alone” Treatment for Cancer or to Be used in Conjunction with other Pharmaceutically Suitable Therapy and Treatment(s) in any percentage ratio as a Treatment for Treating Cancer. | 06-20-2013 |
Qing Lai US
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20110267168 | FUSE - A fuse includes an upper shell, a lower shell and a cavity formed by the upper shell and the lower shell; first and second conductors which are respectively disposed between the upper shell and the lower shell. The first ends of each conductors are disposed in the cavity and form a clearance. The second ends of the conductors extend out from the cavity. A conductive bar is welded to the first and second conductors to form a first weld line and a second weld line. | 11-03-2011 |
Ray Y. Lai, Palo Alto, CA US
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20120047250 | SCALABILITY BREAKPOINT CALCULATOR FOR A SOFTWARE PRODUCT - During a technique for estimating a scalability breakpoint of a software product, performance load tests of the software product are performed with different numbers of simulated concurrent users. For a given number of simulated concurrent users, a performance load test may include an associated set of transactions that are executed by the software product. Furthermore, during the performance load tests performance metrics for the transactions in the associated sets of transactions are measured. Then estimated total performance metrics for the transactions in the associated sets of transactions for the different numbers of simulated concurrent users are determined based on the measured performance metrics and the associated sets of transactions. Next, using the determined estimated total performance metrics, the estimated scalability breakpoint is calculated. | 02-23-2012 |
Rebecca Y. Lai, Lincoln, NE US
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20110139636 | GOLD-PLATED SCREEN-PRINTED ELECTRODES AND THEIR USE AS ELECTROCHEMICAL SENSORS - This disclosure describes a gold-plated screen-printed electrode for use as an electrochemical sensor. | 06-16-2011 |
20110210017 | FABRICATION OF ELECTROCHEMICAL BIOSENSORS VIA CLICK CHEMISTRY - This disclosure describes electrochemical biosensors produced using click chemistry. | 09-01-2011 |
20120315625 | SELF-ASSEMBLED MONOLAYERS AND METHODS FOR USING THE SAME IN BIOSENSING APPLICATIONS - Cross-linked amphiphile constructs that form self-assembled monolayers (SAMs) on metal surfaces such as gold surfaces are disclosed. These new SAMs generate well packed and highly oriented monolayer films on gold surfaces. A method for using the SAMs in the fabrication of biomolecule sensors is also disclosed. | 12-13-2012 |
20140106980 | OPTICAL SENSING AND SEPARATION BASED ON ORDERED THREE-DIMENSIONAL NANOSTRUCTURED SURFACES - A sensor having a substrate is provided in which structures are disposed on a surface of the substrate. The structures can be, e.g., nanostructures. Polarized light is directed toward the sensor, and birefringence of the structures with respect to the light is measured. Target particles that interact with the structures are detected based on changes in the measured birefringence. | 04-17-2014 |
Ronald Lai, Bedford, NH US
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20100068946 | Electrical connector - An electrical connector element including a first second and a second section. The first section has a general hook shape with a first conductor contact surface on an inward facing surface of the general hook shape. The second section is integrally formed with the first section. The second section has a first side forming a second conductor contact surface and an opposite second side. The second side faces the first conductor contact surface. The second side is sized and shaped to slidably interlock directly with another electrical connector element. The second side has at least one wedging surface. | 03-18-2010 |
Samuel K. Lai, Carrboro, NC US
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20120121718 | COMPOSITIONS AND METHODS RELATING TO REDUCED MUCOADHESION - The present invention generally relates to reducing the mucoadhesive properties of a particle. In some embodiments, the particle is coated with and/or associated with a (poly(ethylene glycol))-(poly(propylene oxide))-(poly(ethylene glycol)) triblock copolymer. Methods for preparing inventive particles using a poly(ethylene glycol)-vitamin E conjugate as a surfactant are also provided. In some embodiments, methods are provided comprising administering to a subject a composition of particles of the present invention. Such particles with reduced mucoadhesive properties are useful in delivering agents to mucosal tissues such as oral, ophthalmic, gastrointestinal, nasal, respiratory, and genital mucosal tissues. | 05-17-2012 |
20130164343 | COMPOSITIONS AND METHODS FOR ENHANCING TRANSPORT THROUGH MUCUS - The invention generally relates to compositions and methods for transporting substances across mucosal barriers. The invention also relates to methods of making and using such substances. | 06-27-2013 |
20130236556 | COMPOSITIONS AND METHODS RELATING TO REDUCED MUCOADHESION - The present invention generally relates to reducing the mucoadhesive properties of a particle. In some embodiments, the particle is coated with and/or associated with a (poly(ethylene glycol))-(poly(propylene oxide))-(poly(ethylene glycol)) triblock copolymer. Methods for preparing inventive particles using a poly(ethylene glycol)-vitamin E conjugate as a surfactant are also provided. In some embodiments, methods are provided comprising administering to a subject a composition of particles of the present invention. Such particles with reduced mucoadhesive properties are useful in delivering agents to mucosal tissues such as oral, ophthalmic, gastrointestinal, nasal, respiratory, and genital mucosal tissues. | 09-12-2013 |
20130323179 | NANOCRYSTALS, COMPOSITIONS, AND METHODS THAT AID PARTICLE TRANSPORT IN MUCUS - Nanocrystals, compositions, and methods that aid particle transport in mucus are provided. In some embodiments, the compositions and methods involve making mucus-penetrating particles (MPP) without any polymeric carriers, or with minimal use of polymeric carriers. The compositions and methods may include, in some embodiments, modifying the surface coatings of particles formed of pharmaceutical agents that have a low water solubility. Such methods and compositions can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for administration routes involving the particles passing through a mucosal barrier. | 12-05-2013 |
20150044270 | SUSTAINED DELIVERY OF THERAPEUTIC AGENTS TO AN EYE COMPARTMENT - Compositions and methods for treating eye disorders by administering a drug delivery system into an eye compartment of the patient, wherein the drug delivery system contains a particle containing a core; a coating associated with the particle, wherein the coating is covalently or non-covalently associated with the particle and presents a hydrophilic region to the environment around the particle; and a therapeutic agent are disclosed. The eye compartment can exhibit reduced inflammation or IOP after administration of the drug delivery systems to a patient than if a drug delivery system including an uncoated particle were administered to the patient. | 02-12-2015 |
Sanjaya Lai, San Francisco, CA US
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20120331016 | METHODS AND SYSTEMS FOR CACHING DATA SHARED BETWEEN ORGANIZATIONS IN A MULTI-TENANT DATABASE SYSTEM - Mechanisms and methods for sharing database content between tenants in a multi-tenant database system are provided. The ability to temporarily store metadata related to the shared data for subsequent use optimizes the data transfer process for multiple data transfers. In an embodiment, the metadata is stored for a pre-determined period of time and fetched again after the period elapses if required. The metadata may be erased from temporary storage if an administrator updates the shared data. | 12-27-2012 |
Shih-Kuo Lai US
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20110156001 | NITRIDE-BASED LIGHT-EMITTING DEVICE - A nitride-based light-emitting device includes a substrate and a plurality of layers formed over the substrate in the following sequence: a nitride-based buffer layer formed by nitrogen, a first group III element, and optionally, a second group III element, a first nitride-based semiconductor layer, a light-emitting layer, and a second nitride-based semiconductor layer. | 06-30-2011 |
Shui T. Lai, Windermere, FL US
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20120120369 | SELF GUIDED SUBJECTIVE REFRACTION INSTRUMENTS AND METHODS - A refraction device determines a refraction end point to provide corrective optics for a test subject. The device includes an adjustable optical system providing corrective optics to the test subject and an adjustable viewing target disposed along an optical path such as to be viewable through the adjustable optical system by a test subject. The adjustable viewing target includes a directional indicator linked synchronously to at least two choices of corrective optics presented to the test subject. | 05-17-2012 |
20120120370 | EFFECTIVE ACUITY AND REFRACTION TARGETS - A viewing target for a visual acuity and refraction measurement includes at least one line comprising a width dimension that is below a resolution limit width (hereinafter “RLW”) of a test subject visual acuity, and an adjustable length dimension that is initially set at greater than the RLW of the test subject visual acuity. A base, at least approximately intersecting the line, has a thickness along the direction of the length of the line that is greater than the RLW of the test subject visual acuity. The length dimension of the line is adjustable in increments small enough to effectively approximate the visual acuity of the test subject by determining a shortest resolvable line and a next smaller line that is not resolvable by the test subject. | 05-17-2012 |
20140340645 | EFFECTIVE ACUITY AND REFRACTION TARGETS - A viewing target for a visual acuity and refraction measurement includes at least one line comprising a width dimension that is below a resolution limit width (hereinafter “RLW”) of a test subject visual acuity, and an adjustable length dimension that is initially set at greater than the RLW of the test subject visual acuity. A base, at least approximately intersecting the line, has a thickness along the direction of the length of the line that is greater than the RLW of the test subject visual acuity. The length dimension of the line is adjustable in increments small enough to effectively approximate the visual acuity of the test subject by determining a shortest resolvable line and a next smaller line that is not resolvable by the test subject. | 11-20-2014 |
20140340646 | Self Guided Subjective Refraction Instruments and Methods - A refraction device determines a refraction end point to provide corrective optics for a test subject. The device includes an adjustable optical system providing corrective optics to the test subject and an adjustable viewing target disposed along an optical path such as to be viewable through the adjustable optical system by a test subject. The adjustable viewing target includes a directional indicator linked synchronously to at least two choices of corrective optics presented to the test subject. | 11-20-2014 |
Sing Yeung Lai, Santa Clara, CA US
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20130160142 | Track Changes Permissions - Various features and processes related to document collaboration are disclosed. In some implementations, animations are presented when updating a local document display to reflect changes made to the document at a remote device. In some implementations, a user can selectively highlight changes made by collaborators in a document. In some implementations, a user can select an identifier associated with another user to display a portion of a document that includes the other user's cursor location. In some implementations, text in document chat sessions can be automatically converted into hyperlinks which, when selected, cause a document editor to perform an operation. | 06-20-2013 |
20140071149 | COLOR MANAGEMENT FOR WEB SERVER BASED APPLICATIONS - Method and apparatus for color management of documents retrieved and manipulated by a server based application and displayed on a client device through a browser application. Page elements of documents are manipulated to provide consistent and/or accurate color reproduction on the client device. Pages include untagged images, images tagged with color profiles, and tagged or untagged page elements specified by hex color values. Color values for images and untagged page elements specified by hex color values are adjusted by the server application before transmission to the client device to account for properties of browser applications and operating systems of different client devices. | 03-13-2014 |
Thiet The Lai, Orlando, FL US
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20090029510 | MULTIPLE DOPING LEVEL BIPOLAR JUNCTIONS TRANSISTORS AND METHOD FOR FORMING - A process for forming bipolar junction transistors having a plurality of different collector doping densities on a semiconductor substrate and an integrated circuit comprising bipolar junction transistors having a plurality of different collector doping densities. A first group of the transistors are formed during formation of a triple well for use in providing triple well isolation for complementary metal oxide semiconductor field effect transistors also formed on the semiconductor substrate. Additional bipolar junction transistors with different collector doping densities are formed during a second doping step after forming a gate stack for the field effect transistors. Implant doping through bipolar transistor emitter windows forms bipolar transistors having different doping densities than the previously formed bipolar transistors. According to one embodiment of the present invention, bipolar junction transistors having six different collector dopant densities (and thus six different breakdown characteristics) are formed. | 01-29-2009 |
20100173459 | MULTIPLE DOPING LEVEL BIPOLAR JUNCTIONS TRANSISTORS AND METHOD FOR FORMING - A process for forming bipolar junction transistors having a plurality of different collector doping densities on a semiconductor substrate and an integrated circuit comprising bipolar junction transistors having a plurality of different collector doping densities. A first group of the transistors are formed during formation of a triple well for use in providing triple well isolation for complementary metal oxide semiconductor field effect transistors also formed on the semiconductor substrate. Additional bipolar junction transistors with different collector doping densities are formed during a second doping step after forming a gate stack for the field effect transistors. Implant doping through bipolar transistor emitter windows forms bipolar transistors having different doping densities than the previously formed bipolar transistors. According to one embodiment of the present invention, bipolar junction transistors having six different collector dopant densities (and thus six different breakdown characteristics) are formed. | 07-08-2010 |
20110133289 | MULTIPLE DOPING LEVEL BIPOLAR JUNCTIONS TRANSISTORS AND METHOD FOR FORMING - A process for forming bipolar junction transistors having a plurality of different collector doping densities on a semiconductor substrate and an integrated circuit comprising bipolar junction transistors having a plurality of different collector doping densities. A first group of the transistors are formed during formation of a triple well for use in providing triple well isolation for complementary metal oxide semiconductor field effect transistors also formed on the semiconductor substrate. Additional bipolar junction transistors with different collector doping densities are formed during a second doping step after forming a gate stack for the field effect transistors. Implant doping through bipolar transistor emitter windows forms bipolar transistors having different doping densities than the previously formed bipolar transistors. According to one embodiment of the present invention, bipolar junction transistors having six different collector dopant densities (and thus six different breakdown characteristics) are formed. | 06-09-2011 |
Timothy Lai, Belmont, CA US
Patent application number | Description | Published |
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20120284114 | OPTIMIZED DISPLAY OF AD LANDING PAGE - Methods, systems, and apparatus, including a computer program product for optimizing the display of landing pages in restrictive display environments are provided. A determined area or region of the landing page is identified. Upon receiving a request for content items to be presented on a device, a plurality of content items are identified for presentation on the device, each of the content items having an associated landing page destination address. If the requesting device is a restricted display device, a hash tag is appended to each of the associated destination addresses, each hash tag corresponding to a predefined section of an associated landing page. The plurality of identified content items are transmitted to the requesting device for presentation. | 11-08-2012 |
20120284608 | OPTIMIZED DISPLAY OF THE AD LANDING PAGE - Methods, systems, and apparatus, including a computer program product for optimizing the display of landing pages in restrictive display environments are provided. A determined area or region of the landing page is identified. Upon receiving a request for content items to be presented on a device, a plurality of content items are identified for presentation on the device, each of the content items having an associated landing page destination address. If the requesting device is a restricted display device, a hash tag is appended to each of the associated destination addresses, each hash tag corresponding to a predefined section of an associated landing page. The plurality of identified content items are transmitted to the requesting device for presentation. | 11-08-2012 |
Trevor Irving Lai, Ashland, MD US
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20080215169 | Audio System - A method of selecting an audio source includes the step of providing an audio system that includes a source of audio data which can be supplied to a speaker to produce sound. A portable audio source device is enabled to be operatively connected to the audio system. When the portable audio source device is operatively connected to the audio system, the audio system automatically stops supplying audio data from the source of audio data to the speaker and starts supplying audio data from the portable audio source device to the speaker to produce sound. | 09-04-2008 |
Tsun Yin Lai, Culver City, CA US
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20130156692 | VEGF-SPECIFIC CAPTURE AGENTS, COMPOSITIONS, AND METHODS OF USING AND MAKING - The present application provides biligand and triligand protein-catalyzed capture (PCC) agents that specifically bind VEGF, as well as the use of these capture agents as detection, diagnosis, and treatment agents. | 06-20-2013 |
20140256630 | VEGF-SPECIFIC CAPTURE AGENTS, COMPOSITIONS, AND METHODS OF USING AND MAKING - The present application provides biligand and triligand protein-catalyzed capture (PCC) agents that specifically bind VEGF, as well as the use of these capture agents as detection, diagnosis, and treatment agents. | 09-11-2014 |
Wai Chiu King Lai, East Lansing, MI US
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20080217179 | Classification scheme for nanoobjects - A method is provided for classifying nanoobjects having different electrical properties, such as conductivities and permittivities. The method includes: suspending nanoobjects having different electrical properties in a liquid medium; passing the liquid medium through a microchamber; and filtering nanoobjects having a first type of electrical property from the liquid medium by applying an electric field to the liquid medium in the microchamber. | 09-11-2008 |
20150042781 | NON-VECTOR SPACE SENSING AND CONTROL SYSTEMS AND METHODS FOR VIDEO RATE IMAGING AND MANIPULATION - Compressive sensing based video rate imaging techniques are presented. Rather than scan the entire image, the imaging system only scans part of the topography of the sample as a compressed scan. After the data has been collected, an algorithm for image reconstruction is applied for recovering the image. Because compressive sensing is used, the imaging rate is increased from several minutes per frame to seconds per frame. Non-vector space control techniques are also presented. No-vector space control use image or compressive data as the input and feedback to generate a closed-loop motion control. Compressive sensing technique provides an efficient data reduction method to retain the essential information in the original image. The non-vector space control method can be used as motion control method with compressive feedback without or with noise. | 02-12-2015 |
Wei-Shin Lai, Bellefonte, PA US
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20080304691 | SLEEP AID SYSTEM AND METHOD - A sleep aid system, including a band adapted for surrounding a person's head, the band including an inside fabric layer and an outside fabric layer, two speakers between the fabric layers, the speakers positioned substantially opposite to one another, and an audio input for receiving audio from an audio player. | 12-11-2008 |
William Lai, Philadelphia, PA US
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20110137182 | METHODS AND DEVICES FOR ASSESSING INTRACRANIAL PRESSURE - Provided are methods for noninvasively assessing intracranial pressure (“ICP”) based on optic nerve sheath diameter (“ONSD”) and a blood velocity metric, such as pulsatility or resistivity index. Also provided are related devices and systems for performing the claimed methods. | 06-09-2011 |
20130144185 | Devices and Methods for Noninvasive Measurement of Intracranial Pressure - Provided are systems and methods for noninvasively assessing intracranial pressure by controllably applanating at least a portion of a subject's ocular globe so as to collapse an intraocular blood vessel and correlating the collapse pressure to intracranial pressure. Also provided are ophthalmic components useful in ophthalmic imaging applications, as well as methods of assessing intracranial pressure that are based, at least in part, on the degree of papilledema, if any, present in the subject. | 06-06-2013 |
20130211285 | Devices and Methods for Noninvasive Measurement of Intracranial Pressure - Provided are systems and methods for noninvasively assessing intracranial pressure by controllably osculating at least a portion of a subject's ocular globe while applying a force sufficient to collapse an intraocular blood vessel and correlating the collapse pressure to intracranial pressure. Also provided are ophthalmic components useful in ophthalmic imaging applications, such as retinal, corneal, and pupil imaging. The components may include an optical contact surface that has a radius of curvature that is greater than the radius of curvature of a subject's cornea. | 08-15-2013 |
Wing L. Lai, Williston, VT US
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20090112352 | EQUIVALENT GATE COUNT YIELD ESTIMATION FOR INTEGRATED CIRCUIT DEVICES - A storage medium including a method of modeling yield for semiconductor products includes determining expected faults for each of a plurality of library elements by running a critical area analysis on each of the library elements, and assessing, from the critical area analysis, an expected number of faults per unit area, and comparing the same to actual observed faults on previously manufactured semiconductor products. Thereafter, the expected number of faults for each library element is updated in response to observed yield. A database is established, which includes the die size and expected faults for each of the library elements. Integrated circuit product die size is estimated, and library elements to be used to create the integrated circuit die are selected. Fault and size data for each of the selected library elements are obtained, the adjusted estimated faults for each of the library elements are summed, and estimated yield is calculated. | 04-30-2009 |
20150035073 | ENABLING ENHANCED RELIABILITY AND MOBILITY FOR REPLACEMENT GATE PLANAR AND FINFET STRUCTURES - A method for semiconductor fabrication includes forming at least one of a diffusion barrier layer and a metal containing layer over a dielectric layer in a gate cavity. A first anneal is performed to diffuse elements from the at least one of the diffusion barrier layer and the metal containing layer into the dielectric layer. The metal containing layer and the diffusion barrier layer are removed. A second anneal is performed to adjust diffusion of the elements in the dielectric layer to provide a gate dielectric region. | 02-05-2015 |
Xin-He Lai, Portland, OR US
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20100233211 | ATTENUATED FRANCISELLA AND METHODS OF USE - is the bacterial pathogen that causes tularemia in humans and a number of animals. To date, no approved vaccine exists for this widespread and life-threatening disease. The present disclosure provides attenuated | 09-16-2010 |
Yang Tri Lai, Tigard, OR US
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20090200414 | SPLICING APPARATUS AND METHOD - An apparatus and method for splicing tapes dispensed from a tape dispenser. According to one embodiment, a first, running or unwinding roll of tape is provided with a first splicing element secured to its trailing end portion. A second, stationary or standby roll of tape is provided with a second splicing element secured to its leading end portion. The second splicing element comprises a body made of a self-supporting material and formed with at least one aperture sized to receive the tape from the first roll. While tape is being dispensed from the first roll, the running tape is inserted into the aperture of the second splicing element. When the first roll of tape becomes depleted, the first splicing element engages the second splicing element, thereby splicing the leading end portion of the second tape roll to the trailing end portion of the first tape roll. | 08-13-2009 |
20100123037 | APPARATUS AND METHOD FOR DISPENSING TAPE - A dispensing apparatus includes a first running spool of elongated material and second and third stand-by spools of elongated material. The first spool has a trailing end portion and a first obstacle element secured to its trailing end portion. The second spool has a leading end portion and a first catching mechanism secured to the leading end portion, as well as a trailing end portion with a second obstacle element secured to its trailing end portion. The third spool has a leading end portion and a second catching mechanism secured to its leading end portion. A support member is configured to at least partially support the leading end portions of both the second and third spools. | 05-20-2010 |
Yau S. Lai, Orlando, FL US
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20090293111 | THIRD PARTY SYSTEM FOR BIOMETRIC AUTHENTICATION - A method of authenticating an identity of a user includes launching a user interface and obtaining biometric data of a user at the user interface. The method further includes comparing the biometric data of the user to stored biometric information of the user that was previously obtained during an enrollment process. A comparison result is generated and provided to a third party system documenting if the stored biometric information was satisfied, wherein the third party system is configured to utilize the comparison result to authenticate an identity of the user | 11-26-2009 |
Yen-Lun Lai, Denver, CO US
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20100300927 | Multi-tip charging system - A single electronic charging system that can be used for different electronic components by changing a tip portion of a charging cord of the charging system. A plurality of tip portions are included with a single charging source that interfaces either with an AC power source, a 12 to 24 volt DC power source or a battery power source by merely threading a connector portion of the charging cord onto an electric cable. | 12-02-2010 |
20120152408 | Oil collection assembly - A funnel and drain hose are interengaged in a specific orientation. The drain hose is positioned on the funnel with the opposed ends of the drain hose vertically positioned when the funnel is properly hung on a wall. The opposed ends of the drain hose face upwardly so that any residual oil trapped in the drain hose collects at the bottom of a U-shaped portion of the drain hose positioned on the funnel. | 06-21-2012 |
Zhennan Lai, North Potomac, MD US
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20100183558 | SAFE LENTIVIRAL VECTORS FOR TARGETED DELIVERY OF MULTIPLE THERAPEUTIC MOLECULES - The present application discloses a lentiviral transfer system which includes: (i) a self-inactivating transfer vector comprising: multiple gene units, wherein each gene unit includes a heterologous nucleic acid sequence operably linked to a regulatory nucleic acid sequence; and (ii) a helper construct which lacks a 5′ LTR, wherein the 5′ LTR has been replaced with a heterologous promoter, in which the helper construct further comprises: a lentiviral env nucleic acid sequence containing a deletion, wherein the deleted env nucleic acid sequence does not produce functional env protein; and a packaging signal contains a deletion, wherein the deleted packaging signal is nonfunctional. | 07-22-2010 |
20120027725 | SAFE LENTIVIRAL VECTORS FOR TARGETED DELIVERY OF MULTIPLE THERAPEUTIC MOLECULES TO TREAT LIVER CANCER - The present application discloses a lentiviral transfer system for treating liver cancer which includes: (i) a self-inactivating transfer vector comprising: multiple gene units, wherein each gene unit includes a heterologous nucleic acid sequence operably linked to a regulatory nucleic acid sequence; and (ii) a helper construct which lacks a 5′ LTR, wherein the 5′ LTR has been replaced with a heterologous promoter, in which the helper construct further comprises: a lentiviral env nucleic acid sequence containing a deletion, wherein the deleted env nucleic acid sequence does not produce functional env protein; and a packaging signal contains a deletion, wherein the deleted packaging signal is nonfunctional. | 02-02-2012 |
20120114607 | SAFE LENTIVIRAL VECTORS FOR TARGETED DELIVERY OF MULTIPLE THERAPEUTIC MOLECULES - The present application discloses a lentiviral transfer system which includes: (i) a self-inactivating transfer vector comprising: multiple gene units, wherein each gene unit includes a heterologous nucleic acid sequence operably linked to a regulatory nucleic acid sequence; and (ii) a helper construct which lacks a 5′ LTR, wherein the 5′ LTR has been replaced with a heterologous promoter, in which the helper construct further comprises: a lentiviral env nucleic acid sequence containing a deletion, wherein the deleted env nucleic acid sequence does not produce functional env protein; and a packaging signal contains a deletion, wherein the deleted packaging signal is nonfunctional. | 05-10-2012 |