Patent application number | Description | Published |
20100115370 | METHOD AND APPARATUS FOR ERROR CONCEALMENT OF ENCODED AUDIO DATA - A method of frame error concealment in encoded audio data comprises receiving encoded audio data in a plurality of frames; and using saved one or more parameter values from one or more previous frames to reconstruct a frame with frame error. Using the saved one or more parameter values comprises deriving parameter values based at least part on the saved one or more parameter values and applying the derived values to the frame with frame error. | 05-06-2010 |
20150287418 | METHOD AND APPARATUS FOR RESILIENT VECTOR QUANTIZATION - It is inter alia disclosed to quantise a vector of a plurality of coefficients using a predictive mode of operation of a vector quantiser, wherein the vector quantiser can operate in either a predictive mode of operation or a non-predictive mode of operation, determine a vector of a plurality of recovered coefficients; compare the vector of the plurality of coefficients to the vector of the plurality of recovered coefficients; and determine the mode of operation of the vector quantiser for a vector of a plurality of coefficients associated with a subsequent frame of audio samples, wherein the mode of operation is dependent on the comparison. | 10-08-2015 |
20150332677 | AUDIO CODEC MODE SELECTOR - There is inter alia a method comprising: receiving a request to change the coding rate of a multimode audio codec; determining that the request corresponds to a coding rate of another mode of operation of the multimode audio codec; determining a frame of an input audio signal of the multimode audio codec to be an active region of the audio signal; maintaining a current operating mode of the multimode audio codec; and reducing the coding rate of the multimode audio codec to a coding rate lower than the requested coding rate. | 11-19-2015 |
20160035357 | AUDIO SIGNAL ENCODER COMPRISING A MULTI-CHANNEL PARAMETER SELECTOR - An apparatus comprising: a channel analyser configured to determine for a first frame of at least one audio signal a set of first frame audio signal multi-channel parameters; a multichannel parameter selector configured to select for the first frame a sub-set of the set of first frame audio signal multi-channel parameters based on a value associated with the first frame; and a multichannel parameter encoder configured to generate an encoded first frame audio signal multi-channel parameter based on the selected sub-set of the set of first frame audio signal multi-channel parameters. | 02-04-2016 |
20160064004 | MULTIPLE CHANNEL AUDIO SIGNAL ENCODER MODE DETERMINER - It is inter alia disclosed a method comprising: determining an indication of similarity between a first audio frame of a multiple channel input audio signal and a second audio frame of the multiple channel input audio signal; and determining a coding mode for a multiple channel audio spatial encoder dependent on each of: data indicating a coding mode of a mono audio encoder for the first audio frame of the multiple channel input audio signal; a coding mode of the multichannel spatial audio encoder for the first audio frame of the multiple channel input audio signal; and the indication of similarity. | 03-03-2016 |
20160078877 | AUDIO SIGNAL ENCODER - An apparatus comprising: a channel analyser configured to determine for a first frame of at least one audio signal a set of first frame audio signal multi-channel parameters; a multichannel difference selector configured to select for the first frame groups of elements of the set of first frame audio signal multi-channel parameters based on a value associated with the first frame; and a multichannel parameter encoder configured to generate an encoded first frame audio signal multi-channel parameter based on the selected groups of elements of the set of first frame audio signal multi-channel parameters. | 03-17-2016 |
20160086368 | Image Point of Interest Analyser with Animation Generator - An apparatus comprising a point of interest analyser configured to define at least one region within an image as an interest region, determine a position associated with the at least one region; an audio track generator configured to determine at least one audio signal based on the position; and an animated presentation generator configured to generate an animated image comprising the at least one region and the at least one audio signal. | 03-24-2016 |
20160105602 | METHOD, APPARATUS AND COMPUTER PROGRAM FOR AUTOMATICALLY CAPTURING AN IMAGE - An apparatus comprising: means for processing, at a first time, a user-input to determine a position condition defined in respect of an object that is yet to be included in a sensed image; and means for automatically capturing, after the first time, a sensed image including a first object not included in the sensed image at the first time, in response to determination that the user-input position condition is satisfied in respect of the first object. | 04-14-2016 |
20160111100 | AUDIO SIGNAL ENCODER - An apparatus comprising: a parameter determiner configured to determine for a frame of at least one audio signal a set of frame audio signal multi-channel parameters; a parameter selector configured to select for the frame a sub-set of the set of frame audio signal multi-channel parameters based on an error value associated with the sub-set of the set of frame audio signal multi-channel parameters; and parameter encoder configured to generate an encoded frame audio signal multi-channel parameter based on the selected sub-set of the set of frame audio signal multi-channel parameters. | 04-21-2016 |
Patent application number | Description | Published |
20100014577 | METHOD AND APPARATUS FOR FAST NEAREST NEIGHBOR SEARCH FOR VECTOR QUANTIZERS - A method comprises identifying a component k of a codevector from a codebook C having one or more codevectors, the component k introducing highest variance for an input vector; allowing ordering of codevectors in the codebook C; and searching for a best match vector for the input vector using ordered codevectors. | 01-21-2010 |
20110016077 | AUDIO SIGNAL CLASSIFIER - An apparatus for classifying an audio signal configured to: estimate at least one shaping parameter value for a plurality of samples of the audio signal; generate at least one audio signal classification value by mapping the at least one shaping parameter value to one of at least two interval estimates; and determine at least one audio signal classification decision based on the at least one audio signal classification value. | 01-20-2011 |
20120197649 | Audio Coding - A method for encoding an audio signal including: processing a selected subset of a lower series of samples forming a lower frequency spectral band of the audio signal and a higher series of samples forming a higher frequency spectral band of the audio signal to parametrically encode the higher series of samples forming the higher frequency spectral band by identifying a sub-series of the lower series of samples. | 08-02-2012 |
20130226598 | AUDIO ENCODER OR DECODER APPARATUS - An apparatus comprising at least one processor and at least one memory including computer program code the at least one memory and the computer program code configured to, with the at least one processor, cause the apparatus at least to perform: determining from an audio signal at least a first part and a second part; encoding the first part of the audio signal with a first encoder for generating a first encoded audio signal; encoding the second part of the audio signal with a second encoder configured to generate a second encoded audio signal comprising for a first section of the second part an indicator to at least part of the first part of the audio signal; and determining the first section of the second part of the audio signal such that the first encoded audio signal and second encoded audio signal is within a defined encoding efficiency parameter. | 08-29-2013 |
20130238346 | LOW COMPLEXITY TARGET VECTOR IDENTIFICATION - It is inter alia disclosed to identify one or more target vectors from a plurality of candidate vectors, each candidate vector having sorted elements and being associated with a respective class of one or more code vectors of a codebook and at least one of the candidate vectors being associated with a respective class of two or more code vectors that comprise the respective candidate vector and at least one code vector obtainable from the respective candidate vector by one of permutation and signed permutation, the target vectors having, among all candidate vectors of the plurality of candidate vectors, smallest distances towards a at least sorted representation of an input vector. The identifying comprises checking, for a candidate vector of the plurality of candidate vectors, at least based on a distance between the candidate vector and a reference vector and on a distance between the reference vector and the at least sorted representation of the input vector, if a distance between the at least sorted representation of the input vector and the candidate vector is larger than a distance between the at least sorted representation of the input vector and the reference vector. The identifying further comprises computing, for the candidate vector, the distance between the at least sorted representation of the input vector and the candidate vector only if the checking yields a negative result. | 09-12-2013 |
20130246076 | CODING OF STRINGS - It is inter alia disclosed to apply a function on a string in accordance with a rule of a set of rules, the string comprising first and second representatives, wherein the function ensures that the string comprises at least one of a predetermined representative at an end of the string after the function has been applied; and to determine a representation of the string, wherein said representation comprises at least one encoded representative, each of said at least one encoded representative being associated with at least one representative of the string, wherein said representation does not comprise an encoded representative being associated with at least one of the at least one predetermined representative at the end of the string. | 09-19-2013 |
20140074488 | ENCODING OF STEREOPHONIC SIGNALS - A stereophonic signal is converted into a mid channel signal and a side channel signal. Noise is added to the side channel signal. The amount of noise is selected depending on masking thresholds for at least two channels of the stereophonic signal. The mid channel signal and the modified side channel signal are quantized for transmission. Alternatively or in addition, a set of quantization parameter for the quantization of the side channel signal is selected depending on the masking thresholds. | 03-13-2014 |
20140114653 | PITCH ESTIMATOR - An apparatus comprising an analysis window definer configured to define at least one analysis window for a first audio signal, wherein the at least one analysis window definer is configured to be dependent on the first audio signal and a pitch estimator configured to determine a first pitch estimate for the first audio signal, wherein the pitch estimator is dependent on the first audio signal sample values within the analysis window. | 04-24-2014 |
20140129216 | MULTIPLE SCALE CODEBOOK SEARCH - It is inter alia disclosed to determine, for each set of basis code vectors of a plurality of sets of basis code vectors, a potential basis code vector for encoding an input vector, wherein each set of basis code vectors is associated with at least one scale representative of a plurality of scale representatives, and to determine a code vector for encoding the input vector from a subset of code vectors, said subset of code vectors comprising, for each determined potential basis code vector and each scale representative associated with the set of basis code vectors of the respective potential basis code vector, a code vector based on the respective potential basis code vector scaled by the respective scale representative. | 05-08-2014 |
20140195253 | Audio Signal Encoder - An apparatus comprising: a coding rate determiner configured to determine a first coding bitrate for at least one first frame audio signal multi-channel parameter and a second coding bitrate for at least one second frame audio signal multi-channel parameter, wherein the combined first and second coding bitrate is less than a bitrate limit; a channel analyser configured to determine for a first frame the at least one first frame audio signal multi-channel parameter and configured to determine for a second frame the at least one second frame audio signal multi-channel parameter; a multi-channel parameter determiner configured to generate an encoded first frame audio signal multi-channel parameter within the first coding bitrate from the at least one first frame audio signal multi-channel parameter and configured to generate an encoded at least one second frame audio signal parameter within the second coding bitrate from the at least one second frame audio signal multi-channel parameter; and a multiplexer configured to combine the encoded at least one first frame audio signal multi-channel parameter and the encoded at least one second frame audio signal multi-channel parameter. | 07-10-2014 |
20140247945 | METHOD AND APPARATUS FOR COMMUNICATING WITH AUDIO SIGNALS HAVING CORRESPONDING SPATIAL CHARACTERISTICS - A method, apparatus computer program product are provided to facilitate the utilization of the spatial position of audio signals in order to improve voice quality. In the context of a method, a main mono signal is determined from one or more audio signals that were received. The method also includes determining one or more ambience signals from the one or more audio signals that were received, such as following removal of the main mono signal therefrom. The method also adjusts at least one of a virtual position of the main mono signal for provision to a recipient device or the one or more ambience signals for provision to the recipient device. | 09-04-2014 |
20140254817 | Orientation Free Handsfree Device - Methods, apparatuses, and computer program products are provided to indicate or automatically configure headphone channel orientation based on a physical orientation determination. An apparatus is provided that is configured to at least determine an orientation of the headphone device; analyze the determined orientation; and provide an indication of the determined orientation or adjust the output channel configuration of the apparatus for the headphone device. The apparatus may be further configured to determine the orientation of the headphone device based on at least one of: a head turn position; a direction of one or more audio signals; a direction of movement, wherein the movement is determined based on a determination of acceleration or trajectory of the headphone device; two or more compass data, wherein at least one compass is located in each of the apparatus and the headphone device; and a difference in characteristics of one or more audio signals. | 09-11-2014 |
20140257826 | METHOD AND APPARATUS FOR AUDIO CODING USING CONTEXT DEPENDENT INFORMATION - A method comprising determining a first geographical location; processing contextual dependent data to generate a priori information indicative of the quality of a communication channel associated with the first geographical location, wherein the contextual dependent data comprises at least one communication channel quality measure relating to the first geographical location; determining a codec function signal dependent on the a priori information indicative of the quality of the communication channel associated with the first geographical location; and encoding an audio signal according to the determined codec function signal. | 09-11-2014 |
20140285312 | Audio Mixing Based Upon Playing Device Location - A method including determining location of at least one second device relative to a first device, where at least two of the devices are configured to play audio sounds based upon audio signals; and mixing at least two of the audio signals based, at least partially, upon the determined location(s). | 09-25-2014 |
20140330415 | METHOD AND APPARATUS FOR DETECTING AUDIO SAMPLING RATE - It is inter alia disclosed to receive a set of encoded audio parameters for an audio frame, wherein the set comprises indices representing at least two quantized line spectral frequency coefficients, wherein the audio frame when decoded comprises audio samples digitally sampled at a sampling frequency, wherein the sampling frequency is one of a plurality of sampling frequencies for an audio decoder; to convert the indices to the at least two quantized line spectral frequency coefficients; and to determine the sampling frequency for the audio frame by checking the value of a highest order quantized line spectral frequency coefficient of the at least two quantized line spectral frequency coefficients. | 11-06-2014 |
20140348342 | AUDIO LENS - An apparatus configured to: determine a viewing angle associated with at least one apparatus camera; determine from at least two audio signals at least one audio source orientation relative to an apparatus; and generate at least one spatial filter including at least a first orientation range associated with the viewing angle and a second orientation range relative to the apparatus. | 11-27-2014 |
20150077421 | CREATING A CINEMAGRAPH - An apparatus receives first image data that is based on image data captured by a first camera and second image data that is based on image data captured by a second camera. The apparatus then creates a cinemagraph using the first image data for a static part of the cinemagraph and using the second image data for an animated part of the cinemagraph. Another apparatus could provide at least one of the first and second image data based on a detected corresponding element. | 03-19-2015 |
20150113401 | Method and Apparatus for Rendering of a Media Item - A method comprising determining that a first separate apparatus is proximate to the apparatus, receiving information indicative of a first media item candidate from the first separate apparatus, such that the first media item is associated with the first separate apparatus, determining that a second separate apparatus is proximate to the apparatus, receiving information indicative of a second media item candidate from the second separate apparatus, such that the second media item is associated with the second separate apparatus, determining a rendering media item based, at least in part, on the first media item candidate and the second media item candidate, and causing rendering of the rendering media item is disclosed. | 04-23-2015 |
20150124972 | AUDIO PROCESSING FOR MONO SIGNALS - It is inter alia disclosed to generate a signal representation at least based on a noise reduced component from a signal and on a noise component from the signal, said signal representation comprising at least two channel representations. | 05-07-2015 |
20150138370 | METHOD AND APPARATUS FOR CALIBRATING AN AUDIO PLAYBACK SYSTEM - A method, apparatus and computer program product are provided to facilitate calibration of an audio playback system with a video presented upon a display. In the context of a method, an image including a display from a first location is received. The method also includes determining a dimension of the display within the image and determining an angle of the display based upon the dimension of a display determined within the image and the first location. The method further includes permitting an audio playback system associated with the display to be calibrated, such as with a video to be presented upon the display, based upon the determined angle. A corresponding apparatus and computer program product are also provided. | 05-21-2015 |
20150310871 | STEREO AUDIO SIGNAL ENCODER - An apparatus comprising: a channel analyser configured to determine at least one set of parameters defining a difference between at least two audio signal channels; a value analyser configured to analyse the at least one set of parameters to determine an initial trend; a mapper configured to map instances of the at least one set of parameters according to a first mapping to generate mapped instances with associated order position instances based on the initial trend; and an encoder configured to encode the mapped instances based on the order position of the mapped instances. | 10-29-2015 |
20150380054 | METHOD AND APPARATUS FOR SYNCHRONIZING AUDIO AND VIDEO SIGNALS - A method, apparatus and computer program product are provided to synchronize audio signals with video images that are replayed with a modified motion. In a method, a trajectory is determined for each audio object of an audio signal. The method also determines each of the audio objects to be a transient or non-transient object. The method also causes a respective audio object to be differently extended depending upon whether the audio object is determined to be a transient object or a non-transient object, thereby synchronizing video signals that are to be played back with a predefined motion. The method causes the respective audio object to be differently extended by splitting the transient object into transient segments, inserting silent segments therebetween and maintaining the trajectories of the transient object and/or by repeating the non-transient object with a trajectory that varies based on the predefined motion of the video signals. | 12-31-2015 |
20160027445 | STEREO AUDIO SIGNAL ENCODER - An apparatus comprising a mapper configured to map an instance of a parameter according to a first mapping to generate a first mapped instance; a remapper configured to remap the first mapped instance dependent on the frequency distribution of mapped instances to generate a remapped instance with an associated order position; and an encoder configured to encode the remapped instance dependent on an order position of the remapped instance. | 01-28-2016 |
Patent application number | Description | Published |
20080205309 | VIRTUAL ADAPTATION LAYER FOR WIRELESS COMMUNICATION - A system for improving communication efficiency in a communication medium. In at least one embodiment of the present invention, communication efficiency in a wireless communication medium may be improved by routing communication packets to destination layers in a wireless protocol stack using a minimal amount of information. Communication packets may be routed by maintaining a set of virtual packet identification indicators for identifying and routing information to an appropriate communication layer, receiving information including a virtual packet identification; and resolving an information type and a communication protocol layer to which the received data should be routed by mapping the virtual packet identification included in the received information with the virtual packet identification indicators. | 08-28-2008 |
20090164480 | METHODS, APPARATUS AND COMPUTER PROGRAM PRODUCT FOR ALTERING DEVICE FUNCTIONALITY - A method, apparatus, system and computer program product are provided which permit the functionality of a device to be adapted or otherwise altered without requiring the device to be completely reprogrammed. In this regard, attributes which at least partially define the functionality of the device may be changed or supplemented in order to correspondingly alter the device functionality which, in turn, at least partially depends upon the attributes stored by the device. | 06-25-2009 |
20100303236 | METHOD AND APPARATUS FOR PROPAGATING ENCRYPTION KEYS BETWEEN WIRELESS COMMUNICATION DEVICES - A system for propagating encryption key information between wireless communication devices without the requirement of pairing each and every device. A wireless communication device may be paired with at least one device in a group of devices. When a secure link is established between these devices, a determination may be made as to whether encryption key information should be passed from one device to another. The additional encryption key information may allow a wireless communication device to create a secure link with other devices without having to first establish a trusted relationship (e.g., go through a pairing process) with the other devices. | 12-02-2010 |
20120042098 | Method and Apparatus for Implementing Address Privacy in Communications Networks - Various methods for implementing address privacy in communications networks are provided. One method may include receiving a lower layer address block. The lower layer address block may include a random component and a lower layer solution component. The random component may include a random value and the lower layer solution component may be based at least in part on the random value and a shared key. The method may also include verifying the lower layer address block via the random value and the shared key. The method may further include receiving a higher layer address block. The higher layer address block may include a higher layer solution component. The higher layer solution component may be based at least in part on the random value and a shared key. The method may further include verifying the higher layer address block via the random value and the shared key. Similar apparatuses and computer program products are also provided. | 02-16-2012 |
20120196534 | METHOD, APPARATUS, AND COMPUTER PROGRAM PRODUCT FOR BROADCASTING IN SHORT-RANGE COMMUNICATION - Method, apparatus, and computer program product example embodiments establish a broadcast operating mode on a Bluetooth Low Energy data channel by creating operating parameters for a data channel broadcast connection. Then data channel broadcast connection parameters are transmitted to other devices indicating the data channel broadcast connection and the operating parameters associated with the data channel broadcast connection are transmitted on a Bluetooth Low Energy advertising channel. Then information on the Bluetooth Low Energy data channel broadcast connection to the other devices, according to the operating parameters associated with the data channel broadcast connection. The bit rate of the Bluetooth Low Energy data channel used for broadcasting is not constrained by the required limits placed on the bit rate in the Bluetooth Low Energy advertising channels. | 08-02-2012 |
20130023295 | METHOD, APPARATUS, AND COMPUTER PROGRAM PRODUCT FOR WIRELESS NETWORK DISCOVERY BASED ON GEOGRAPHICAL LOCATION - Method, apparatus, and computer program product embodiments are disclosed for wireless resource sharing between heterogeneous wireless networks to enable coexistence of secondary networks. An example embodiment of the invention includes a method, comprising: receiving, at an apparatus or entity, information associated with a wireless network; determining, by the apparatus or entity, a geographic communication area and one or more geographic interference areas associated with the wireless network based on the received information; transmitting, by the apparatus or entity, a message to a destination to register the wireless network and the determined geographic communication area and one or more geographic interference areas associated with the wireless network; and receiving, by the apparatus or entity, confirmation of the registering of the wireless network at the destination and information associated with zero or more wireless networks that at least one of potentially interfere with the determined geographic communication area associated with the wireless network, or potentially experience interference caused by the determined one or more interference areas associated with the wireless network. | 01-24-2013 |
Patent application number | Description | Published |
20120258123 | BIOMARKERS FOR SENSITIVE DETECTION OF STATIN-INDUCED MUSCLE TOXICITY - The present invention inter alia provides a method, and uses thereof, of predicting statin-induced muscle toxicity or its complications, such as myalgia, myopathy and rhabdomyolysis, by detecting the lipid concentrations or lipid-lipid concentration ratios of a biological sample and comparing them to a control. This method has identified lipid markers that are more specific and sensitive in detecting these statin-induced muscle toxicity than the currently utilized clinical markers. Also provided is an antibody towards said lipids, and the use thereof for predicting, diagnosing, statin-induced muscle toxicity. The invention additionally relates to kits comprising lipids and/or an antibody thereto, for use in the prediction and/or diagnosis of statin-induced muscle toxicity. | 10-11-2012 |
20130045217 | LIPIDOMIC BIOMARKERS FOR ATHEROSCLEROSIS AND CARDIOVASCULAR DISEASE - The present invention inter alia provides a method, and use thereof, of diagnosing and/or predicting atherosclerosis or CVD by detecting the lipid concentrations or lipid ratios of a biological sample and comparing it to a control and has identified specific lipid markers that are more specific and sensitive in detecting and predicting atherosclerosis and CVD than currently utilized clinical markers. Also provided is an antibody towards said lipids, and the use thereof for predicting, diagnosing, preventing and/or treating atherosclerosis or CVD. The invention additionally relates to kits comprising lipids and/or an antibody thereto, for use in the prediction and/or diagnosis of atherosclerosis or CVD. | 02-21-2013 |
20130216560 | Lipidomic Biomarkers for Identification of High-Risk Coronary Artery Disease Patients - The present invention inter alia provides a method, and use thereof, of predicting severe CVD complications such as AMI or CVD death by detecting the lipid concentrations or lipid ratios of a biological sample and comparing it to a control and has identified specific lipid markers that are more specific and sensitive in predicting these CVD complications than currently utilized clinical markers. Also provided is an antibodies towards said lipids, and the use thereof for predicting, diagnosing, preventing and/or treating CVD complications. The invention additionally relates to kits comprising lipids and/or an antibody thereto, for use in the prediction and/or diagnosis of CVD complications. | 08-22-2013 |
20140031332 | Biomarkers for Sensitive Detection of Statin-Induced Muscle Toxicity - The present invention inter alia provides a method, and uses thereof, of predicting statin-induced muscle toxicity or its complications, such as myalgia, myopathy and rhabdomyolysis, by detecting the lipid concentrations or lipid ratios of a biological sample and comparing it to a control. This method has identified lipid markers that are more specific and sensitive in detecting these statin-induced muscle toxicity than the currently utilized clinical markers. Also provided is an antibody towards said lipids, and the use thereof for predicting, diagnosing, statin-induced muscle toxicity. The invention additionally relates to kits comprising lipids and/or an antibody thereto, for use in the prediction and/or diagnosis of statin-induced muscle toxicity. | 01-30-2014 |
20140295466 | LIPIDOMIC BIOMARKERS FOR THE PREDICTION OF CARDIOVASCULAR OUTCOMES IN CORONARY ARTERY DISEASE PATIENTS UNDERGOING STATIN TREATMENT - The present invention inter alia provides a method, and use thereof, of predicting severe CVD complications such as AMI or CVD death by detecting the lipid concentrations or lipid ratios of a biological sample and comparing it to a control and has identified specific lipid markers that are more specific and sensitive in predicting these CVD complications than currently utilized clinical markers. Also provided are antibodies towards said lipids, and the use thereof for predicting, diagnosing, preventing and/or treating CVD complications. The invention additionally relates to kits comprising lipids and/or an antibody thereto, for use in the prediction and/or diagnosis of CVD complications. | 10-02-2014 |
20140295467 | LIPIDOMIC BIOMARKERS FOR THE PREDICTION OF CARDIOVASCULAR OUTCOMES IN CORONARY ARTERY DISEASE PATIENTS NOT UNDERGOING STATIN TREATMENT - The present invention inter alia provides a method, and use thereof, of predicting severe CVD complications such as AMI or CVD death by detecting the lipid concentrations or lipid ratios of a biological sample and comparing it to a control and has identified specific lipid markers that are more specific and sensitive in predicting these CVD complications than currently utilized clinical markers. Also provided are antibodies towards said lipids, and the use thereof for predicting, diagnosing, preventing and/or treating CVD complications. The invention additionally relates to kits comprising lipids and/or an antibody thereto, for use in the prediction and/or diagnosis of CVD complications. | 10-02-2014 |
20150160247 | Sensitive Efficacy and Specificity Biomarkers for Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition - The present invention inter alia provides a method, and uses thereof, to measure drug efficacy and specificity of treatment with an inhibitor of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) by detecting the concentrations of lipids and/or lipid-lipid concentration ratios of a biological sample and comparing it to a control. The invention is applicable, inter alia, to determining whether a PCSK9 inhibiting drug is functioning efficiently in lowering serum low-density lipoprotein (LDL) concentration and whether a PCSK9 inhibiting drug displays any adverse side-effects, such as liver toxicity. Provided are lipid markers that are more specific and sensitive in detecting drug efficacy and possible adverse drug-induced side-effects than the currently utilized clinical markers. Also provided is an antibody towards said lipids, and the use thereof for predicting and diagnosing of PCSK9 inhibiting drug-induced adverse reactions. The invention additionally relates to kits comprising lipids and/or an antibody thereto, for the determination of PCSK9 inhibiting drug efficacy and drug-induced adverse reactions. | 06-11-2015 |
20150247873 | LIPIDOMIC BIOMARKERS FOR ATHEROSCLEROSIS AND CARDIOVASCULAR DISEASE - The present invention inter alia provides a method, and use thereof, of diagnosing and/or predicting atherosclerosis or CVD by detecting the lipid concentrations or lipid ratios of a biological sample and comparing it to a control and has identified specific lipid markers that are more specific and sensitive in detecting and predicting atherosclerosis and CVD than currently utilized clinical markers. Also provided is an antibody towards said lipids, and the use thereof for predicting, diagnosing, preventing and/or treating atherosclerosis or CVD. The invention additionally relates to kits comprising lipids and/or an antibody thereto, for use in the prediction and/or diagnosis of atherosclerosis or CVD. | 09-03-2015 |
20150260737 | LIPIDOMIC BIOMARKERS FOR THE PREDICTION OF CARDIOVASCULAR OUTCOMES IN CORONARY ARTERY DISEASE PATIENTS NOT UNDERGOING STATIN TREATMENT - The present invention inter alia provides a method, and use thereof, of predicting severe CVD complications such as AMI or CVD death by detecting the lipid concentrations or lipid ratios of a biological sample and comparing it to a control and has identified specific lipid markers that are more specific and sensitive in predicting these CVD complications than currently utilized clinical markers. Also provided are antibodies towards said lipids, and the use thereof for predicting, diagnosing, preventing and/or treating CVD complications. The invention additionally relates to kits comprising lipids and/or an antibody thereto, for use in the prediction and/or diagnosis of CVD complications. | 09-17-2015 |
20150260738 | LIPIDOMIC BIOMARKERS FOR THE PREDICTION OF CARDIOVASCULAR OUTCOMES IN CORONARY ARTERY DISEASE PATIENTS UNDERGOING STATIN TREATMENT - The present invention inter alia provides a method, and use thereof, of predicting severe CVD complications such as AMI or CVD death by detecting the lipid concentrations or lipid ratios of a biological sample and comparing it to a control and has identified specific lipid markers that are more specific and sensitive in predicting these CVD complications than currently utilized clinical markers. Also provided are antibodies towards said lipids, and the use thereof for predicting, diagnosing, preventing and/or treating CVD complications. The invention additionally relates to kits comprising lipids and/or an antibody thereto, for use in the prediction and/or diagnosis of CVD complications. | 09-17-2015 |
20150362513 | CERAMIDES AND THEIR USE IN DIAGNOSING CVD - The present invention inter alia provides a method, and use thereof, of predicting CV complications such as AMI, ACS, stroke, and CV death by determining the concentrations of at least one ceramide of Group A and at least one ceramide of Group B in a biological sample and comparing those concentrations to a control. Finding a decreased concentration of at least one Group A ceramide and an increased concentration of at least one Group B ceramide indicates that the subject has an increased risk of developing one or more CV complications. Also provided are a newly identified subset of ceramide molecules, labelled versions thereof, and kits and compositions comprising the same for use in predicting and/or diagnosing CV complications. | 12-17-2015 |