Patent application number | Description | Published |
20090011036 | Drug containing hollow protein nanoparticles of particle-forming protein, fused with disease-treating target-cell-substance - The subject invention provides a disease-treating drug that uses hollow protein nanoparticles to specifically act on a target cell or tissue. The present invention allows a protein drug to be effectively capsulated in the particles. The invention also provides a therapeutic method using such a drug. The drug according to the present invention is capable of recognizing a specific cell, such as hepatocytes, and manufactured by fusing a disease-treating substance for a target cell (for example, interferon, hepatocyte growth factor etc.) with hollow nanoparticles of a particle-forming protein (for example, hepatitis B virus surface-antigen protein). | 01-08-2009 |
20090275110 | Microorganism that Displays Biotin on Cell Surface - Provided is a microorganism that can display, on the cell surface, any molecules other than a molecule comprising amino acids, more specifically, a microorganism that displays biotin on a cell surface. The microorganism is capable of co-expressing a biotinylating enzyme and an acceptor peptide having a sequence recognized by the biotinylating enzyme, wherein the acceptor peptide is expressed on the cell surface, so that lysine of the acceptor peptide is biotinylated to display biotin on the cell surface. Also provided is a method for displaying an intended molecule, including not only a molecule comprising amino acids but also any molecules, on a cell surface of a microorganism. | 11-05-2009 |
20100190223 | YEAST FOR TRANSFORMATION, TRANSFORMATION METHOD, AND METHOD FOR PRODUCING SUBSTANCE - Yeast for transformation is provided, which enables introduction of a greater number of copies of a target gene or a greater number of types of target genes. A method provided herein comprises the steps of introducing a target gene into yeast for transformation, which has homothallic properties and a plurality of selection markers, and selecting a strain in which the target gene has been introduced based on the selection markers in the yeast for transformation, whereby multiple target genes were introduced owing to the homothallic properties of the yeast for transformation. | 07-29-2010 |
20110033906 | METHOD FOR PRODUCING USEFUL SUBSTANCE FROM CELLULOSE-CONTAINING MATERIAL - The present invention provides a method for producing a useful substance efficiently from cellulose without using any cellulase preparation. According to the disclosures of the present specification, in the production of a useful substance from a cellulose-containing material, the cellulose-containing material is brought into contact with an ionic liquid to cause the ionic liquid to permeate the cellulose-containing material, and a carbon source comprising the cellulose in the cellulose-containing material is simultaneously saccharified and fermented by a cellulase-producing microorganism in the presence of the ionic liquid. | 02-10-2011 |
20120149116 | CELLULOSE DEGRADABLE YEAST AND METHOD FOR PRODUCTION THEREOF - The present invention provides a method for producing a cellulose degradable yeast, comprising the step of co-introducing genes coding for at least two cellulose-degrading enzymes into a yeast host via integration with a yeast δ sequence. According to the invention, a yeast having an improved cellulose degradation ability are provided. | 06-14-2012 |
20130017266 | Radiation Therapy AgentAANM Ogino; ChiakiAACI Kobe-shiAACO JPAAGP Ogino; Chiaki Kobe-shi JPAANM Tanaka; TsutomuAACI Kobe-shiAACO JPAAGP Tanaka; Tsutomu Kobe-shi JPAANM Sasaki; RyoheiAACI Kobe-shiAACO JPAAGP Sasaki; Ryohei Kobe-shi JPAANM Kondo; AkihikoAACI Kobe-shiAACO JPAAGP Kondo; Akihiko Kobe-shi JP - Provided is a radiotherapeutic agent, including a composite particle, which is obtained by binding a molecule that specifically recognizes a target to a substrate particle including titanium peroxide, and which generates reactive oxygen through irradiation with a radiation. Further, because the radiotherapeutic agent contains the molecule that specifically recognizes a target, the radiotherapeutic agent has a function of accumulating in the target. The radiotherapeutic agent is capable of enhancing effects of radiotherapy, and is capable of reducing side effects on a living body to efficiently attack the target. | 01-17-2013 |
20140120598 | Novel Method For Producing Ethanol - Provided is a novel method of producing ethanol by using a cellulose-based biomass as a raw material. In particular, provided is a novel method of producing ethanol by which ethanol can be effectively produced in the presence of a substance having an inhibitory action on fermentation of ethanol. Ethanol can be effectively produced by using a microorganism engineered to suppress the expression of at least one kind of phosphatase among the phosphatases intrinsically possessed by the microorganism, even under a condition where a substance that has heretofore been believed to have a fermentation inhibitory action, specifically, a weakly acidic substance and/or a furan compound are/is incorporated. | 05-01-2014 |
Patent application number | Description | Published |
20130274367 | SURFACE MODIFICATION METHOD, SURFACE-MODIFIED ELASTIC BODY, GASKET FOR INJECTOR, INJECTOR, AND TIRE - Provided are: surface modification method for imparting slidability to surface of elastic body such as vulcanized rubber or thermoplastic elastomer without using expensive self-lubricating resin; surface-modified elastic body with polymer brush formed on its surface; and gasket for injector and injector formed of surface-modified elastic body. The surface modification method applies to surface of thermoplastic elastomer or vulcanized rubber. The surface modification method comprises the step of forming hydroxyl group on surface of to-be-modified object such as rubber so that water contact angle of the surface becomes 8 to 50 degrees smaller than original water contact angle in unmodified condition, the step of forming polymerization initiation site by subjecting the hydroxyl group to action of secondary or tertiary organic halide, and the step of growing polymer brush on the surface of to-be-modified object by subjecting monomer to radical polymerization at the polymerization initiation site acting as a point of initiation. | 10-17-2013 |
20150231337 | GASKET FOR PREFILLED SYRINGE AND PREFILLED SYRINGE - A gasket for prefilled syringe according to the present invention is a gasket for prefilled syringe that includes a fluid contacting portion, a sliding portion with a circumferential surface, a film layer made of a fluororesin coated on the fluid contacting portion and sliding portion and further, and a coating layer including trimethylsiloxysilicate laminated on the film layer covering the sliding portion. | 08-20-2015 |
20150266984 | SURFACE MODIFICATION METHOD, SURFACE-MODIFIED ELASTIC BODY, GASKET FOR INJECTOR, INJECTOR, AND TIRE - Provided are: surface modification method for imparting slidability to surface of elastic body such as vulcanized rubber or thermoplastic elastomer without using expensive self-lubricating resin; surface-modified elastic body with polymer brush formed on its surface; and gasket for injector and injector formed of surface-modified elastic body. The surface modification method applies to surface of thermoplastic elastomer or vulcanized rubber. The surface modification method comprises the step of forming hydroxyl group on surface of to-be-modified object such as rubber so that water contact angle of the surface becomes 8 to 50 degrees smaller than original water contact angle in unmodified condition, the step of forming polymerization initiation site by subjecting the hydroxyl group to action of secondary or tertiary organic halide, and the step of growing polymer brush on the surface of to-be-modified object by subjecting monomer to radical polymerization at the polymerization initiation site acting as a point of initiation. | 09-24-2015 |