Kolodkin
Alex L. Kolodkin, Berkeley, CA US
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20080312158 | Semaphorin Gene Family - A novel class of proteins, semaphorins, nucleic acids encoding semaphorins, semaphorin peptides, and methods of using semaphorins and semaphorin-encoding nucleic acids are disclosed. Semaphorin peptides and receptor agonists and antagonists provide potent modulators of nerve cell growth and regeneration. The invention provides pharmaceutical compositions, methods for screening chemical libraries for regulators of cell growth/differentiation; semaphorin gene-derived nucleic acids for use in genetic mapping, as probes for related genes, and as diagnostic reagents for genetic neurological disease; specific cellular and animal systems for the development of neurological disease therapy. | 12-18-2008 |
Alex L. Kolodkin, Baltimore, MD US
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20110256544 | MOLECULES INTERACTING WITH CASL (MICAL) POLYNUCLEOTIDES, POLYPEPTIDES, AND METHODS OF USING THE SAME - The present invention provides MICAL and MICAL-Like polypeptides and polynucleotides. Also provided are methods that for identifying agents that affect axon growth and placement. Furthermore, provided herein are methods for affecting axon growth and placement. | 10-20-2011 |
Alex Leo Kolodkin, Baltimore, MD US
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20120208207 | Sample Processing Device - A floating chamber set may include a plurality of containers coupled to a frame such that each container translates vertically within a limited vertical range independent of the other containers. Each container may be perforated to allow liquid penetration. | 08-16-2012 |
Arkadi Kolodkin, Tel Aviv IL
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20080196577 | Safe Inspection System and Kit - A safe inspection system for the manual inspection of personal luggage, which comprises an inspection module including at least one inspection member which defines an inspection surface, for supporting a potentially explosive object for manual inspection by an inspector; a blast containment container arranged in a position of immediate communication with the inspection module; and transfer means for effecting the immediate transfer of a suspicious inspected object from the inspection surface to the blast containment container by an inspector without requiring further handling of the object by the inspector, thereby to immediately confine the object within the blast containment container and so as to thus reduce the reduce blast damage in the event that the suspicious object explodes after confinement therewithin. The present invention also includes a kit for converting a blast containment container to a safe inspection system. | 08-21-2008 |
Nikolai Kolodkin, St. Petersburg RU
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20100158900 | ANTI-MARINOBUFAGENIN ANTIBODIES AND METHODS FOR THEIR USE - Described herein are deposited hybridoma cell lines and the monoclonal antibodies produced by these hybridomas, and antigen binding fragments thereof. These monoclonal antibodies and antigen binding fragments specifically bind marinobufagenin. The disclosure also encompasses the use of these monoclonal antibodies or antigen binding fragments in a method for detecting the presence of marinobufagenin in a biological sample. Also provided are methods for the use of these monoclonal antibodies or antigen binding fragments as prophylactic, therapeutic, and diagnostic agents for the detection, inhibition and treatment of a cardiovascular disease, for example, essential hypertension, hypertension associated with preeclampsia, eclampsia, or renal failure, or myocardial fibrosis in a subject. | 06-24-2010 |