Koller, CH
Adrian A. Koller, Pfeffikon CH
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20160037711 | SINGULATING HAND PLANTER AND FERTILIZER APPLICATOR - A device and method for hand planting cereal grain seed, and other crops where singulation (single seeds planted per strike) is taught. The device and method are capable of serving as a small scale fertilizer and alternative product applicator. The inventive method includes the capability of applying fertilizer and/or other products that are collected and dispensed via a reciprocating drum device. The device preferably includes a tapered (or pointed) soil engagement component capable of striking or penetrating the soil surface. With each planter strike to the soil surface, the device is actuated to meter a granular material product and the reciprocating drum rotates to expose the cavity to a material hopper. As the actuation force is released, the reciprocating drum rotates in the opposite direction to its original location and drops the material that has been metered. | 02-11-2016 |
Beat Koller, Uster CH
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20130342225 | Capacitive Analysis of a Moving Test Material - The capacitive measuring circuit for a moved elongated test material contains at least two measuring capacitors, each of which is configured for receiving the test material. It further contains electrically actuatable selection means, by means of which one of the measuring capacitors can be selected in such a way that only the selected measuring capacitor contributes to the measurement, whereas the other measuring capacitors do not. As a result, the total capacitance of the measuring circuit is reduced and its sensitivity is increased. | 12-26-2013 |
Claudia Ferrara Koller, Zuerich CH
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20080248510 | HUMAN Fc GAMMA RECEPTOR III - The present invention relates to the field of human immunoglobulin receptors, specifically the glycostructure of a human Fc gamma receptor IIIa recombinantly expressed in human embryonic kidney cells and Chinese hamster ovary cells. | 10-09-2008 |
20110183354 | HUMAN Fc GAMMA RECEPTOR III - The present invention relates to the field of human immunoglobulin receptors, specifically the glycostructure of a human Fc gamma receptor IIIa recombinantly expressed in human embryonic kidney cells and Chinese hamster ovary cells. | 07-28-2011 |
Edmond Koller, Geneve CH
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20140294676 | HYDROGEN SENSOR WITH ACTIVE LAYER AND METHOD OF MANUFACTURING HYDROGEN SENSORS - Hydrogen sensor including a substrate (S) on which there is deposited an active layer of material comprising a first element selected from the rare earth family, a second element selected from the platinum group metals (PGMs) and a third element selected from the alkaline earth metal family. | 10-02-2014 |
Erich Koller, Basel CH
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20150315580 | COMPOUNDS AND METHODS FOR IMPROVING CELLULAR UPTAKE OF OLIGOMERIC COMPOUNDS - The present invention provides method of optimizing the efficacy and potency of antisense drugs. In certain embodiments, the invention provides assays useful for determining favorable oligonucleotide characteristics and excipeints for improved cellular uptake. | 11-05-2015 |
20150322428 | COMPOUNDS AND METHODS FOR IMPROVED CELLULAR UPTAKE OF ANTISENSE COMPOUNDS - The present invention provides method of increasing the efficacy and potency of antisense compounds. In certain embodiments, the invention provides methods for improved cellular uptake. In certain embodiments, the resulting antisense activity is greater at a particular concentration of antisense compound than the antisense activity at the same concentration of the antisense compound in the absence of the ESCRT modulator. | 11-12-2015 |
Felix Koller, Schniznach-Dorf CH
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20100116018 | METHOD FOR CHECKING A KNOCKING DEVICE - A method is provided for checking a knocking device which is intended for cleaning the surface of a heat exchanger element arranged on the inside of a boiler housing of a garbage incineration plant and which has a knocking ram guided through the wall of the boiler housing and movable in the direction toward the inside of the boiler. The heat exchanger element is deflected out of its position of rest into a deflection position by means of the knocking ram, and the force required for deflecting the heat exchanger element and/or the attenuation behavior of the heat exchanger element released after deflection are/is determined. | 05-13-2010 |
Horst Koller, Engelburg CH
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20110062047 | Method Of Preparing Macromolecule Deterrent Surface On a Pharmaceutical Packages - A method of preparing a macromolecule deterrent surface on a pharmaceutical package. In particular, the present invention relates to a method of preparing a protein deterrent surface on a pharmaceutical package by applying a coating or coatings directly to the pharmaceutical package that reduces the adsorption of proteins onto pharmaceutical packaging while not affecting the activity of the protein solution contained. | 03-17-2011 |
Horst Koller, Uznach CH
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20100044268 | PHARMACEUTICAL PACKAGE HAVING A MULTI-FUNCTIONAL SURFACE AND A METHOD OF PREPARING A MULTI-FUNCTIONAL SURFACE ON A PHARMACEUTICAL PACKAGE - The present invention relates to a multi-functional pharmaceutical package surface and a method of preparing a multi-functional pharmaceutical package surface. In particular, the present invention relates to a pharmaceutical package having a protein deterrent and lubricious surface and methods of preparing said surface by applying coatings directly to the pharmaceutical package that (a) reduce the adsorption of proteins onto pharmaceutical packaging while not affecting the activity of the protein solution and (b) provide a lubricious surface. The pharmaceutical package surface may also contain a barrier coating. Coatings can be deposited on a variety of pharmaceutical packaging materials and configurations by various methods. | 02-25-2010 |
20110177955 | MULTIPLEXED PROTEIN ADSORPTION ASSAY - A multiplexed assay method capable of measuring the interaction of one or more protein, polypeptide or peptide solutions with one or more substrate surfaces comprises contacting each of the wells of a multiwell substrate with the same or different protein solution, the surfaces of said wells being the same as that of said substrate or being substrate surface treated and/or coated to provide test surfaces, and determining the level of protein adsorption in each of said wells. | 07-21-2011 |
Manuel Koller, Basel CH
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20140018376 | Use of 1H-Quinazoline-2,4-Diones - The invention concerns the use of competitive AMPA receptor antagonists for the treatment, prevention or delay of progression of Rasmussen's encephalitis and/or certain forms of epilepsy. | 01-16-2014 |
Manuel Koller, Schliern CH
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20080262030 | Organic Compounds - The present invention relates to compounds of formula (I) | 10-23-2008 |
20090023797 | Indol-Alanine Derivatives as Selective S1P4-Agonists - The present invention relates to agonists of the S1P4 receptor, which are selective for the S1P4 receptor over one or more of the S1P1, S1P2, S1P3 or S1P5 receptors of at least 10 fold, in particular new indol-alanine derivatives of structure 1, process for their production, their uses, in particular in transplantation, and pharmaceutical compositions containing them | 01-22-2009 |
20090029960 | MACROCYCLIC COMPOUNDS USEFUL AS BASE INHIBITORS - The invention relates to novel macrocyclic compounds of the formula | 01-29-2009 |
20100144747 | 1H-QUINAZ0LINE-2,4-DIONES - The present invention relates to 1H-Quinazoline-2,4-diones of formula (I) | 06-10-2010 |
20100179127 | PYRIMIDINE DERIVATIVES - The invention relates to novel heterocyclic compounds of the formula | 07-15-2010 |
20100184775 | ORGANIC COMPOUNDS - The present invention relates to compounds of formula (I) wherein n represents 0, 1, 2, 3, 4 or 5, R represents independent from each other hydroxyl, cyano, nitro, halogen, alkyl, alkoxy alkylcarbonyl, alkoxycarbonyl, alkylamine, dialkylamine, alkylcarbonylamine, alkylcarbamate Y represents one of the following groups: (Ia) in free base or acid addition salt form, to processes for their production, to pharmaceutical compositions comprising them and their use in the manufacture of a medicament for the treatment and/or delay of progression of psychotic and neurodegenerative disorders. | 07-22-2010 |
20110294818 | 1H-QUINAZOLINE-2,4-DIONES - The present invention relates to 1H-Quinazoline-2,4-diones of formula (I) | 12-01-2011 |
20130274294 | 4-(Hetero)Aryl-Ethynyl-Octahydro-Indole-1-Esters - The invention relates to compound of the formula (I) or a salt thereof, wherein the substituents are as defined in the specification; to its preparation, to its use as medicament and to medicaments comprising it. | 10-17-2013 |
20130296332 | 1H-QUINAZOLINE-2,4-DIONES - The present invention relates to 1H-Quinazoline-2,4-diones of formula (I) | 11-07-2013 |
20140057902 | Diazepinone derivatives - The invention relates to compound of the formula I | 02-27-2014 |
20140256940 | 1-AZA-BICYCLO[3.3.1] NON-4-YL)-[5-(1H-INDOL-5-YL)-HETEROARYL]-AMINES AS CHOLINERGIC LIGANDS OF THE N-ACHR FOR THE TREATMENT OF PSYCHOTIC AND NEURODEGENERATIVE DISORDERS - The present invention related to compounds of formula (I) wherein n represents 0, 1, 2, 3, 4 or 5, represents independent from each other hydroxyl, cyano, nitro, halogen, alkyl, alkoxy alkylcarbonyl, alkoxycarbonyl, alkylamine, dialkylamine, alkylcarbonylamine, alkylcarbamate, Y represents one of the following groups: (Ia) in free base or acid addition salt form, to processes for their production, to pharmaceutical compositions comprising them and their use in the manufacture of a medicament for the treatment and/or delay of progression of psychotic and neurodegenerative disorders. | 09-11-2014 |
20140357625 | DIAZEPINONE DERIVATIVES - The invention relates to compound of the formula I | 12-04-2014 |
Martin Koller, Wildegg CH
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20120151922 | STEAM TURBINE OVERSPEED PROTECTION METHOD AND SYSTEM - A method and system is disclosed for generating a steam turbine overspeed control system fault alert. The method can include providing an overspeed control system with a control valve configured and located to adjust a speed of the steam turbine, the control valve having a control position. The method can also include monitoring the control position of the control valve and detecting a deloading event. Upon detection of a deloading event, a control system fault alert is generated when the control valve does not achieve a predefined control position within a predefined time from the deloading event. | 06-21-2012 |
20130061591 | ADIABATIC COMPRESSED AIR ENERGY STORAGE SYSTEM AND METHOD - During an adiabatic compressed air energy storage (ACAES) system's operation, energy imbalances may arise between thermal energy storage (TES) in the system and the thermal energy required to raise the temperature of a given volume of compressed air to a desired turbine entry temperature after the air is discharged from compressed air storage of the ACAES system. To redress this energy imbalance it is proposed to selectively supply additional thermal energy to the given volume of compressed air after it received thermal energy from the TES and before it expands through the turbine. The additional thermal energy is supplied from an external source, i.e. fuel burnt in a combustor. The amount of thermal energy added to the given volume of compressed air after it received thermal energy from the TES is much smaller than the amount of useful work obtained from the given volume of compressed air by the turbine. | 03-14-2013 |
Martin Koller, Baden CH
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20110265475 | METHOD AND APPARATUS FOR COLD STARTING A STEAM TURBINE - The disclosure relates to a method and apparatus for cold starting a steam turbine by preheating a steam turbine component using eddy currents. The process includes providing an electrically conducting steam turbine component, an electro-magnetic coil, and a supply of AC to the coil. The coil is located relative to the component so that the coil is capable of forming eddy currents in the component. In this location, an AC current is passed through the coil thus heating the component. | 11-03-2011 |
Michael Koller, Dottingen CH
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20100253004 | ELEMENT FOR SEALING OR REINFORCING A CAVITY AND METHOD FOR INTRODUCING A PENETRATING ELEMENT INTO SUCH AN ELEMENT - In the case of an element for sealing or reinforcing a cavity of a structural element, in particular of a vehicle, the element comprises a base element a foamable part, and an opening for receiving a penetrating element. A wing is arranged on the base element, the opening is open at the side, and an actuator which moves the wing when the penetrating element is introduced is arranged on the wing. | 10-07-2010 |
Tobias Loreaz Florien Koller, Zurich CH
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20090051876 | Presbyopia Correction Program - A method of generating a computer program for control of an apparatus for photorefractive treatment of presbyopia by ablation of corneal tissue or a contact lens, comprising the following steps: | 02-26-2009 |
Tobias Lorenz Florian Koller, Zurich CH
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20110190743 | Presbyopia Correction Program - Systems and methods for treating presbyopia are provided. In one embodiment, a system for photorefractive treatment of presbyopia includes a laser source configured for ablating corneal tissue and a control system in communication with the laser source and configured to control the laser source to ablate conical tissue of a patient to achieve a desired corneal shape. In some instances, the control system controls the laser source by calculating a global optimum regarding curvature and asphericity of the cornea. In some instances, control system controls the laser source by calculating a central steep island and calculating a curvature and asphericity for the rest of the cornea. In some embodiments, a laser source is controlled to ablate the cornea of the patient in accordance with a calculated shape profile to achieve a desired corneal shape. | 08-04-2011 |