Patent application number | Description | Published |
20100111967 | BISPECIFIC ANTI-VEGF/ANTI-ANG-2 ANTIBODIES - The present invention relates to bispecific antibodies against human VEGF and against human ANG-2, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 05-06-2010 |
20110236388 | BISPECIFIC, BIVALENT ANTI-VEGF/ANTI-ANG-2 ANTIBODIES - The present invention relates to bispecific, bivalent antibodies against human vascular endothelial growth factor (VEGF/VEGF-A) and against human angiopoietin-2 (ANG-2), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 09-29-2011 |
20120020988 | Antibodies specifically binding to human TSLPR and methods of use - An antibody specifically binding to human thymic stromal lymphopoietin receptor (TSLPR), characterized in comprising as heavy chain variable domain CDR regions a CDR1 region of SEQ ID NO:2 or 17, a CDR2 region of SEQ ID NO:3 or 10, and CDR3 region of SEQ ID NO:4, and as light chain variable domain CDR regions a CDR1 region of SEQ ID NO:6 or 12, a CDR2 region of SEQ ID NO:7, 13 or 15, and a CDR3 region of SEQ ID NO:8. is useful for the treatment of immunological diseases. | 01-26-2012 |
20120190609 | METHOD FOR PRODUCING A LIPID PARTICLE, THE LIPID PARTICLE ITSELF AND ITS USE - A method for producing a lipid particle comprising the following: i) providing a first solution comprising denatured apolipoprotein, ii) adding the first solution to a second solution comprising at least two lipids and a detergent but no apolipoprotein, and iii) removing the detergent from the solution obtained in ii) and thereby producing a lipid particle. | 07-26-2012 |
20120237506 | Antigen Binding Proteins - The present invention relates to antigen binding proteins comprising two Fc parts, methods for their production, pharmaceutical compositions containing said antigen binding proteins, and uses thereof. | 09-20-2012 |
20120237507 | Monovalent Antigen Binding Proteins - The present invention relates to monovalent antigen binding proteins with a CH1-CL domain exchange, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 09-20-2012 |
20120321627 | BISPECIFIC ANTI-VEGF/ANTI-ANG-2 ANTIBODIES - The present invention relates to bispecific antibodies against human VEGF and against human ANG-2, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 12-20-2012 |
20130065277 | SEQUENCE DEPENDENT AGGREGATION - Herein is reported a method for reducing the aggregation of an immunoglobulin in solution comprising the steps of i) comparing the amino acid sequence of the fourth framework region of the heavy chain of an antibody with a reference or germline sequence and determining whether one or more threonine residues and/or serine residues have been replaced by a different amino acid residue, and ii) modifying the amino acid sequence of the immunoglobulin by reverting the exchanged threonine residues and/or serine residues back to threonine or serine of the reference or germline sequence and thereby reducing the aggregation of an immunoglobulin in solution. | 03-14-2013 |
20150132307 | BISPECIFIC ANTIBODIES AGAINST HUMAN TWEAK AND HUMAN 1L17 AND USES THEREOF - The present invention relates to Bispecific antibodies against human TWEAK and human IL17 (bispecific TWEAK-IL17 antibodies), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof | 05-14-2015 |
20150175685 | HUMANIZED ANTI-Tau(pS422) ANTIBODIES AND METHODS OF USE - The invention provides humanized anti-human Tau(pS422) antibodies and methods of using the same. | 06-25-2015 |
20150191535 | BISPECIFIC, BIVALENT ANTI-VEGF/ANTI-ANG2 ANTIBODIES - The present invention relates to bispecific, bivalent antibodies against human vascular endothelial growth factor (VEGF/VEGF-A) and against human angiopoietin-2 (ANG-2), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 07-09-2015 |
Patent application number | Description | Published |
20100038875 | Vehicle Suspension Including a Link - A link of a vehicle suspension is elastic and includes three suspension points. A first point is adapted to be pivotally connected to a wheel carrier of the corresponding vehicle. A second point is adapted to be pivotally connected to a rigid chassis of the corresponding vehicle. The third point is adapted to be pivotally connected to a shackle, the shackle pivotally connecting the third point to the rigid chassis of the vehicle. | 02-18-2010 |
20150183285 | Vehicle Wheel Suspension of Control Blade Design - A vehicle wheel suspension of a control blade design has three wheel-guiding control arms essentially oriented in the transverse direction of the vehicle and one longitudinal control arm fastened rigidly to the wheel carrier and barely limiting its transverse movement with respect to the vehicle body. The longitudinal control arm is constructed of a fiber composite material and is also rigidly fastened to the vehicle body and thereby takes over the function of a main spring between the wheel carrier and the vehicle body. Other than stop springs integrated in a vibration damper, no further main spring element is provided between the wheel carrier and the vehicle body. The above-mentioned longitudinal control arm may be formed by two, in a wide area, individual control arm parts, which are essentially situated in a common vertical plane, specifically such that the first control arm part of the longitudinal control arm is fastened to the wheel carrier above the wheel center, and second control arm part is fastened to the wheel carrier below the wheel center. The two control arm parts, guided together with their other ends in a common fastening element, are, as required, slightly elastically fastened to the vehicle body. | 07-02-2015 |