Patent application number | Description | Published |
20080200930 | APPARATUS FOR MANIPULATING AND SECURING TISSUE - Apparatus for manipulating and securing tissue are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have an elongate tubular member, an engagement member slidably disposed through the tubular member and a distal end adapted to engage tissue via a helical member, tissue stabilizing members positioned at the tubular member distal end which are adapted to stabilize tissue therebetween, and a delivery tube pivotable about the tissue stabilizer. The stabilizing members can be adapted to become angled relative to a longitudinal axis of the elongate tubular member. Moreover, one or all the articulation controls and functions can be integrated into a singular handle assembly connectable to the tissue manipulation assembly via a rigid or flexible tubular body. | 08-21-2008 |
20080208225 | APPARATUS FOR SEALING SURGICAL PUNCTURES - Apparatus is provided for sealing a puncture within a vessel or tissue to provide hemostasis, comprising a first disk coupled to either a second disk or a spring, and sealingly engaged to the vessel or tissue surrounding the puncture. At least the first disk is preferably configured to substantially conform to the profile of the vessel or tissue when deployed. In one embodiment, the disks may be released from engagement with the vessel or tissue to reposition the disks after deployment. | 08-28-2008 |
20080208226 | APPARATUS FOR SEALING SURGICAL PUNCTURES - Apparatus is provided for sealing a puncture within a vessel or tissue to provide hemostasis, comprising a first disk coupled to either a second disk or a spring, and sealingly engaged to the vessel or tissue surrounding the puncture. At least the first disk is preferably configured to substantially conform to the profile of the vessel or tissue when deployed. In one embodiment, the disks may be released from engagement with the vessel or tissue to reposition the disks after deployment. | 08-28-2008 |
20090076598 | Everting Heart Valve - The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve. In some embodiments, the replacement valve is adapted to wrap about the anchor, for example, by everting during endovascular deployment. In some embodiments, the replacement valve is not connected to expandable portions of the anchor. In some embodiments, the anchor is configured for active foreshortening during endovascular deployment. In some embodiments, the anchor includes expandable lip and skirt regions for engaging the patient's heart valve during deployment. In some embodiments, the anchor comprises a braid fabricated from a single strand of wire. In some embodiments, the apparatus includes a lock configured to maintain anchor expansion. The invention also includes methods for endovascularly replacing a patient's heart valve. In some embodiments, the method includes the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve, wrapping at least a portion of the replacement valve about the anchor, and expanding the anchor to a deployed configuration. | 03-19-2009 |
20090264997 | Everting Heart Valve - The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve. In some embodiments, the replacement valve is adapted to wrap about the anchor, for example, by everting during endovascular deployment. In some embodiments, the replacement valve is not connected to expandable portions of the anchor. In some embodiments, the anchor is configured for active foreshortening during endovascular deployment. In some embodiments, the anchor includes expandable lip and skirt regions for engaging the patient's heart valve during deployment. In some embodiments, the anchor comprises a braid fabricated from a single strand of wire. In some embodiments, the apparatus includes a lock configured to maintain anchor expansion. The invention also includes methods for endovascularly replacing a patient's heart valve. In some embodiments, the method includes the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve, wrapping at least a portion of the replacement valve about the anchor, and expanding the anchor to a deployed configuration. | 10-22-2009 |
20100137860 | APPARATUS FOR PERFORMING A NON-CONTINUOUS CIRCUMFERENTIAL TREATMENT OF A BODY LUMEN - Methods and apparatus are provided for non-continuous circumferential treatment of a body lumen. Apparatus may be positioned within a body lumen of a patient and may deliver energy at a first lengthwise and angular position to create a less-than-full circumferential treatment zone at the first position. The apparatus also may deliver energy at one or more additional lengthwise and angular positions within the body lumen to create less-than-full circumferential treatment zone(s) at the one or more additional positions that are offset lengthwise and angularly from the first treatment zone. Superimposition of the first treatment zone and the one or more additional treatment zones defines a non-continuous circumferential treatment zone without formation of a continuous circumferential lesion. Various embodiments of methods and apparatus for achieving such non-continuous circumferential treatment are provided. | 06-03-2010 |
20100249773 | HANDLE ASSEMBLIES FOR INTRAVASCULAR TREATMENT DEVICES AND ASSOCIATED SYSTEMS AND METHODS - The present disclosure comprises handle assemblies for intravascular treatment devices. In one embodiment, a handle assembly comprises an actuator for deflecting a distal region of an intravascular treatment device. In one embodiment, a handle assembly comprises a rotator for rotating an intravascular treatment device independently of the handle assembly. In one embodiment, a handle assembly comprises a rotation limiting element for limiting independent rotation of an intravascular treatment device relative to the handle assembly. Methods and systems for intravascular delivery, deflection and placement of an intravascular treatment device via a handle assembly of the present invention are also provided. | 09-30-2010 |
20100305608 | AUTOLOGOUS WOUND SEALING APPARATUS - The apparatus is provided for sealing a vascular puncture tract by forming the autologous plug within the puncture tract, and extruding that plug into the puncture tract. The apparatus of the present invention forms an autologous blood plug by drawing blood into the apparatus from a vessel, mixing a blood congealing agent with the drawn blood, and ejecting a plug formed from the clotted blood within the puncture tract. Also provided are various closure elements to isolate the drawn blood from the vessel during mixture with the blood congealing agent, and to facilitate placement of the apparatus relative to the vessel. | 12-02-2010 |
20100325008 | METHODS FOR TRANSFORMING AN AUCTIONED ITEM OF UNKNOWN VALUE AND BUYER INTO AN AUCTIONED ITEM OF KNOWN VALUE AND BUYER - Methods, including methods conducted with a computer system and/or over a telecommunications network, are provided for transforming an auctioned item of unknown value and buyer into an auctioned item of known value and buyer. The methods comprise sealed bid, second-best price auctions that diminish the effects of information asymmetry while aligning the interests of buyers and sellers by reducing common auction risks of the winner's curse, buyer's remorse, bid shading, shill bidding, bid sniping, and/or collusion. Bidders submit sealed bids for the auctioned item. At a successful auction's conclusion, a highest bidder is established as the item's buyer and a second-best price is established as the value. This second-best price is the second highest sealed bid obtained, or a reserve price that the highest bidder accepts as the value for the auctioned item when the highest sealed bid is the only sealed bid at least equal to the reserve price. The second-best price optionally may be one bid increment more than the second highest sealed bid or the reserve price. | 12-23-2010 |
20110190772 | POWERED TISSUE MODIFICATION DEVICES AND METHODS - A device for modifying tissue in a spine may include: a shah having a proximal portion and a distal portion, the distal portion having dimensions which allow h to be passed into an epidural space of the spine and between target and non-target tissues at least one distal force application member extending from the distal portion of the shall and configured to facilitate application of at least one of anchoring force and tensioning force to the shaft; at least one movable tissue modifying member coupled with the shaft at or near its distal portion; at least one drive member coupled with the at least one tissue modifying member to activate the at least one tissue modifying member; and at least one power transmission member coupled with the at least one drive member to deliver power to the at least one drive member. | 08-04-2011 |
20110200171 | METHODS AND APPARATUS FOR RENAL NEUROMODULATION VIA STEREOTACTIC RADIOTHERAPY - The present disclosure describes methods and apparatus for renal neuromodulation via stereotactic radiotherapy for the treatment of hypertension, heart failure, chronic kidney disease, diabetes, insulin resistance, metabolic disorder or other ailments. Renal neuromodulation may be achieved by locating renal nerves and then utilizing stereotactic radiotherapy to expose the renal nerves to a radiation dose sufficient to reduce neural activity. A neural location element may be provided for locating target renal nerves, and a stereotactic radiotherapy system may be provided for exposing the located renal nerves to a radiation dose sufficient to reduce the neural activity, with reduced or minimized radiation exposure in adjacent tissue. Renal nerves may be located and targeted at the level of the ganglion and/or at postganglionic positions, as well as at pre-ganglionic positions. | 08-18-2011 |
20110264011 | MULTI-DIRECTIONAL DEFLECTABLE CATHETER APPARATUSES, SYSTEMS, AND METHODS FOR RENAL NEUROMODULATION - Multi-directional deflectable catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device comprising an elongated shaft. The elongated shaft is sized and configured to deliver a thermal element to a renal artery via an intravascular path. Thermally or electrical renal neuromodulation may be achieved via direct and/or via indirect application of thermal and/or electrical energy to heat or cool, or otherwise electrically modulate, neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. | 10-27-2011 |
20110264075 | CATHETER APPARATUSES, SYSTEMS, AND METHODS FOR RENAL NEUROMODULATION - Catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device comprising an elongated shaft. The elongated shaft is sized and configured to deliver an energy delivery element to a renal artery via an intravascular path. Thermal or electrical renal neuromodulation may be achieved via direct and/or via indirect application of thermal and/or electrical energy to heat or cool, or otherwise electrically modulate, neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. | 10-27-2011 |
20120027872 | APPARATUS FOR SEALING A PUNCTURE BY CAUSING A REDUCTION IN THE CIRCUMFERENCE OF THE PUNCTURE - Apparatus is provided for sealing a vascular puncture by causing a reduction in the circumference of the puncture tract through delivery of a closure agent into tissue surrounding the puncture tract. A resultant inflammatory response and volumetric increase cause the tissue to swell into the puncture tract, thereby sealing it. | 02-02-2012 |
20120124719 | METHODS AND APPARATUS FOR EAR PROTECTION - Methods and apparatus are provided for protecting the external ear from the elements, heat, cold, wind, rain and/or snow. In some embodiments, an ear protector comprises a conforming anchor with an opening through which the external ear may be passed. The ear protector further comprises an insulating outer covering that, in combination with the anchor, forms the ear protector with a chamber positioned between the outer covering and the anchor. During use, the chamber is configured to receive the external ear, with the anchor's opening conformably positioned in proximity to at least a portion of the ear's root. The perimeter of the conforming anchor's opening resiliently deforms during passage of the external ear through the opening and into the chamber, and then conforms to the geometry of at least a portion of the ear root in order to securely and comfortably maintain the ear protector in position over the external ear without additional external support. The conforming anchor preferably is fabricated from a closed cell foamed elastomer. | 05-24-2012 |
20120165924 | Method and Device for Treatment of Mitral Insufficiency - A device for treatment of mitral annulus dilation is disclosed, wherein the device comprises two states. In a first of these states the device is insertable into the coronary sinus and has a shape of the coronary sinus. When positioned in the coronary sinus, the device is transferable to the second state assuming a reduced radius of curvature, whereby the radius of curvature of the coronary sinus and the radius of curvature as well as the circumference of the mitral annulus is reduced. | 06-28-2012 |
20120296348 | APPARATUS FOR MANIPULATING AND SECURING TISSUE - Apparatus for manipulating and securing tissue are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have an elongate tubular member, an engagement member slidably dispose through the tubular member and a distal end adapted to engage tissue via a helical member, tissue stabilizing members positioned at the tubular member distal end which are adapted to stabilize tissue therebetween, and a delivery tube pivotable about the tissue stabilizer. The stabilizing members can be adapted to become angled relative to longitudinal axis of the elongate tubular member. Moreover, one or all the articulation controls and functions can be integrated into a singular handle assembly connectable to the tissue manipulation assembly via a rigid or flexible tubular body. | 11-22-2012 |
20130006300 | AUTOLOGOUS WOUND SEALING APPARATUS - The apparatus is provided for sealing a vascular puncture tract by forming the autologous plug within the puncture tract, and extruding that plug into the puncture tract. The apparatus of the present invention forms an autologous blood plug by drawing blood into the apparatus from a vessel, mixing a blood congealing agent with the drawn blood, and ejecting a plug formed from the clotted blood within the puncture tract. Also provided are various closure elements to isolate the drawn blood from the vessel during mixture with the blood congealing agent, and to facilitate placement of the apparatus relative to the vessel. | 01-03-2013 |
20130012867 | METHODS AND APPARATUS FOR PERFORMING A NON-CONTINUOUS CIRCUMFERENTIAL TREATMENT OF A BODY LUMEN - Methods and apparatus are provided for non-continuous circumferential treatment of a body lumen. Apparatus may be positioned within a body lumen of a patient and may deliver energy at a first lengthwise and angular position to create a less-than-full circumferential treatment zone at the first position. The apparatus also may deliver energy at one or more additional lengthwise and angular positions within the body lumen to create less-than-full circumferential treatment zone(s) at the one or more additional positions that are offset lengthwise and angularly from the first treatment zone. Superimposition of the first treatment zone and the one or more additional treatment zones defines a non-continuous circumferential treatment zone without formation of a continuous circumferential lesion. Various embodiments of methods and apparatus for achieving such non-continuous circumferential treatment are provided. | 01-10-2013 |
20130238019 | METHOD FOR PREVENTING BLOOD LEAKAGE FROM A VESSEL - A method is provided for preventing leakage of blood from a vessel. The method includes inserting a portion of an apparatus into a puncture tract extending through tissue to a puncture in the vessel; the apparatus including a thrombogenic matrix disposed in a distal portion of the apparatus. The method also includes deploying the thrombogenic matrix from the distal portion of the apparatus and into the puncture tract, the thrombogenic matrix being exposed to blood and compressively engaging the tissue surrounding the vessel to prevent leakage of blood. | 09-12-2013 |
20130310837 | POWERED TISSUE MODIFICATION DEVICES AND METHODS - A device for modifying tissue in a spine may include: a shaft having a proximal portion and a distal portion, the distal portion having dimensions which allow it to be passed into an epidural space of the spine and between target and non-target tissues; at least one distal force application member extending from the distal portion of the shaft and configured to facilitate application of at least one of anchoring force and tensioning force to the shaft; at least one movable tissue modifying member coupled with the shaft at or near its distal portion; at least one drive member coupled with the at least one tissue modifying member to activate the at least one tissue modifying member; and at least one power transmission member coupled with the at least one drive member to deliver power to the at least one drive member. | 11-21-2013 |
20140148828 | APPARATUS AND METHODS FOR FORMING AND SECURING GASTROINTESTINAL TISSUE FOLDS - Apparatus and methods are provided for forming a gastrointestinal tissue fold by engaging tissue at a first tissue contact point and moving the first tissue contact point from a position initially distal to, or in line with, a second tissue contact point to a position proximal of the second contact point, thereby forming the tissue fold, and extending an anchor assembly through the tissue fold from a vicinity of the second tissue contact point. Adjustable anchor assemblies; as well as anchor delivery systems, shape-lockable guides and methods for endoluminally performing medical procedures, such as gastric reduction, treatment of gastroesophageal reflux disease, resection of lesions, and treatment of bleeding sites; are also provided. | 05-29-2014 |
20140303618 | MULTI-DIRECTIONAL DEFLECTABLE CATHETER APPARATUSES, SYSTEMS, AND METHODS FOR RENAL NEUROMODULATION - Multi-directional deflectable catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device comprising an elongated shaft. The elongated shaft is sized and configured to deliver a thermal element to a renal artery via an intravascular path. Thermally or electrical renal neuromodulation may be achieved via direct and/or via indirect application of thermal and/or electrical energy to heat or cool, or otherwise electrically modulate, neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. | 10-09-2014 |
20150057654 | Catheter Apparatuses, Systems, and Methods for Renal Neuromodulation - Catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device comprising an elongated shaft. The elongated shaft is sized and configured to deliver an energy delivery element to a renal artery via an intravascular path. Thermal or electrical renal neuromodulation may be achieved via direct and/or via indirect application of thermal and/or electrical energy to heat or cool, or otherwise electrically modulate, neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. | 02-26-2015 |