Patent application number | Description | Published |
20080221062 | Hyaluronic Acid Derivative and Drug Containing the Same - A hyaluronic acid derivative in which an anti-inflammatory drug is bound to hyaluronic acid through a covalent bond via a spacer having a biodegradable region, and a production process thereof. | 09-11-2008 |
20080251591 | THERMOELEMENT AND THERMOSTAT APPARATUS USING THE THERMOELEMENT - According to the present invention, there is provided a thermoelement that suppresses the corrosion or corrosion products occurring on an outer peripheral surface of a piston and an inner wall of a guide portion so that the piston reciprocates surely and smoothly, and a thermostat apparatus using this thermoelement. The thermoelement according to the present invention includes a wax case that internally has a wax, which is an expanding body, a piston to which responsive action of the expansion and contraction of the wax is transmitted, and a guide portion that guides the sliding of the piston, wherein the guide portion is made of brass containing 69 mass % or more and 80 mass % or less of copper component, 2 mass % or more and 4 mass % or less of silicon component, 0.1 mass % or less of lead component, and the balance of zinc, and the piston is made of stainless steel. | 10-16-2008 |
20080306022 | Agent for Applying to Mucosa and Method for the Production Thereof - An agent for applying to mucosa capable of persistently exerting a therapeutic effect on disorders such as inflammation and lesions in the mucosa even by a lower frequency of administration because the agent can stay at a diseased site for a long period of time by exhibiting a high staying property in a mucosal epithelial layer is provided, said agent for application to mucosa containing glycosaminoglycan (GAG) into which a hydrophobic group is introduced via a binding chain, as an active ingredient. | 12-11-2008 |
20090118348 | DRUG-INTRODUCED PHOTO-CROSSLINKED HYALURONIC ACID DERIVED GEL - A drug-introduced photo-crosslinked hyaluronic acid derived gel which is a photo-crosslinked hyaluronic acid gel into which a drug is introduced through a covalent bond, and has characteristics that are capable of extruding from an injection device. The drug-introduced photo-cross-linked hyaluronic acid derived gel is capable of extruding, for example, by an injection needle of 20 to 25 gauge with a pressure of 0.5 to 5 kg/cm | 05-07-2009 |
20110053885 | PHARMACEUTICAL AGENT HAVING LONG-LASTING EFFECT OF TREATING ARTHRITIC DISORDERS - The present invention relates to an injection solution for intra-articular administration for treating arthritic disorders comprising a cross-linked hyaluronic acid derivative wherein part of functional groups of a hyaluronic acid are cross-linked with a cross-linking group to the extent of 0.6 to 15% of cross-linking extent as an active ingredient in an amount having a long-lasting analgesic effect and a pharmaceutically acceptable carrier, and an analgesic composition for suppressing a cartilage degeneration caused by arthritic disorders or a composition for suppressing a cartilage degeneration or an inflammation of synovium caused by arthritic disorders each comprising the cross-linked hyaluronic acid derivative and a pharmaceutically acceptable carrier. | 03-03-2011 |
20110207695 | AGENT FOR APPLYING TO MUCOSA AND METHOD FOR THE PRODUCTION THEREOF - An agent for applying to mucosa capable of persistently exerting a therapeutic effect on disorders such as inflammation and lesions in the mucosa even by a lower frequency of administration because the agent can stay at a diseased site for a long period of time by exhibiting a high staying property in a mucosal epithelial layer is provided, said agent for application to mucosa containing glycosaminoglycan (GAG) into which a hydrophobic group is introduced via a binding chain, as an active ingredient. | 08-25-2011 |
20150094280 | PHARMACEUTICAL AGENT HAVING LONG-LASTING EFFECT OF TREATING ARTHRITIC DISORDERS - The present invention relates to an injection solution for intra-articular administration for treating arthritic disorders comprising a cross-linked hyaluronic acid derivative wherein part of functional groups of a hyaluronic acid are cross-linked with a cross-linking group to the extent of 0.6 to 15% of cross-linking extent as an active ingredient in an amount having a long-lasting analgesic effect and a pharmaceutically acceptable carrier, and an analgesic composition for suppressing a cartilage degeneration caused by arthritic disorders or a composition for suppressing a cartilage degeneration or an inflammation of synovium caused by arthritic disorders each comprising the cross-linked hyaluronic acid derivative and a pharmaceutically acceptable carrier. | 04-02-2015 |
20150196574 | AGENT FOR APPLYING TO MUCOSA AND METHOD FOR THE PRODUCTION THEREOF - An agent for applying to mucosa capable of persistently exerting a therapeutic effect on disorders such as inflammation and lesions in the mucosa even by a lower frequency of administration because the agent can stay at a diseased site for a long period of time by exhibiting a high staying properly in a mucosal epithelial layer is provided, said agent for application to mucosa containing glycosaminoglycan (GAG) into which a hydrophobic group is introduced via a binding chain, as an active ingredient. | 07-16-2015 |