Keightley
John Andrew Keightley, Kansas City, MO US
Patent application number | Description | Published |
---|---|---|
20090210207 | SYSTEM AND METHOD FOR SEQUENCE VARIATION/PREDICTION AND GENETIC ENGINEERING DETECTION USING DOCUMENTED CODON/AMINO ACID MUTATION AND/OR SUBSTITUTION PATTERNS - The present invention primarily relates to protein identification and can be particularly useful for bioinformaticists employing a mass spectrometry analysis. The present invention provides systems and methods to produce virtual databases, virtual database entries, or virtual amino acid sequences that can be used to improve the identification of unknown proteins and facilitate recognizing engineered proteins and distinguishing between natural and engineered genes and proteins. The present invention uses variations, such as mutation or substitution patterns, evident in and derived from known DNA, RNA, and protein sequences to predict and generate virtual DNA, RNA, and amino acid sequences that may not be represented in the current databases but that are likely to occur in nature. Substitution patterns may be derived from either the chemical, physical, and biological patterns of mutation or the derived, observable patterns of evolutionary fixation of such mutations between or within species. These virtual sequences (or databases/datafiles of such virtual sequences) contain novel, but statistically likely sequences for use in comparing to unknown proteins (peptides) for protein identification. The use of such synthetic sequences and/or databases facilitate the recognition and distinction between naturally occurring and genetically engineered DNA, RNA, and protein sequences. | 08-20-2009 |
John Howard Keightley, Langley CA
Patent application number | Description | Published |
---|---|---|
20100060904 | HAND-HELD SURFACE PROFILER - A light-emitting hand-held surface profiler for scanning and profiling the surfaces of objects has a transparent housing, a focusable light source, a conical mirror aligned to redirect light emitted by the light source onto a surface to be profiled, an imaging sensor and a lens aligned to redirect toward the imaging sensor light reflected by the surface onto the lens. The light source, conical mirror, imaging sensor and lens are mounted within the housing and positionally referentially coupled to the housing. | 03-11-2010 |
Kym Keightley, Fairview Park AU
Patent application number | Description | Published |
---|---|---|
20140183827 | CHUCK TOOL AND BITS - A tool arrangement and chuck apparatus for quick change of a range of tools; particularly, a quick change chuck adapted to engage various diameter drill bits, tools and tool holders. The tools are rotatable in a chuck or adaptor and have at one end a centering shaft portion having a constant diameter for multiple tool end diameters and shapes, a drive shoulder portion and a lock portion. The chucks have a tool centering arrangement for accommodating the constant diameter centering shaft. The chucks are also described as having tool bit release mechanism operable to disengage the tool from a retention mechanism when a force is applied inwards of the body of the chuck by the user to allow the tool bit to be removed longitudinally from the chuck but also arrange to allow the tool bit to be inserted longitudinally into the chuck without requiring any other user operation. | 07-03-2014 |
Kym John Keightley, Fairview Park AU
Patent application number | Description | Published |
---|---|---|
20090038353 | Dual lock apparatus - The present invention relates to a dual lock apparatus ( | 02-12-2009 |
20100067995 | HOLE SAW ASSEMBLY INCLUDING DRIVE SHAFTS SUPPORTED BY A ROTATABLE ANNULUS - A hole-saw assembly including a hole-saw having at one end a plurality of cutting teeth and at the other end a base having two holes therethrough. two shafts. The assembly includes a mandrel coaxially aligned with said hole-saw and including a body having two bores therethrough, and an annulus located on top of the body which is coaxially aligned with said mandrel and hole saw. The annulus includes two shafts co-axial with the mandrel bores, and is rotatable around its longitudinal axis from a first to a second position. In the first position the annulus shafts are aligned with the base holes allowing the shafts to be freely insertable and removable and in the second position the shafts are misaligned to lock the shafts to the base. In one embodiment the mandrel bores are shaped to accommodate rotation of the shafts, and in a further embodiment, the shafts are configures to rotate within circular mandrel bores. Such an arrangement allows the hole-saw and the mandrel to be easily and quickly mountable and demountable. | 03-18-2010 |
20100080665 | HOLE SAW WITH INTERCHANGEABLE CUTTING BLADES - A hole saw having a central body portion adapted to receive a hole saw blade portion. The body and the blade have correspondingly shaped apertures and lugs that co-operate together to hold the blade in place. A locking means further assists in ensuring that the blade remains locked to the body and includes a sliding klatch that engages an aperture in the blade and the body and is itself locked in place to thereby lock the blade to the body. | 04-01-2010 |
Kym John Keightley, Adelaide AU
Patent application number | Description | Published |
---|---|---|
20100247258 | Hole saw assembly - The present invention relates to a hole-saw assembly includes a hole-saw having at one end a plurality of cutting teeth and with a boss attached to the hole-saw at the other end two shafts. The assembly includes a mandrel coaxially aligned with said hole-saw and including a body having two bores there through coaxially aligned with said shafts. An annulus located on top of the body is coaxially aligned with said mandrel and hole saw and includes two holes, the annulus rotatable around its longitudinal axis from a first to a second position. In the first position the annulus holes are aligned with the bores and shafts allowing the shafts to be freely insertable and removable and in the second position the holes are misaligned to lock the shafts to the annulus. The mandrel further includes a pair of driving pins adapted to engage driving apertures found in hole-saws especially larger ones. Typically the driving pins may be biased to enable the assembly to be used even with those hole-saws that do not include driving apertures and that also enables easier assembly of the device. A compressible O-ring may further facilitate the operation of the assembly. This device avoids the problem of thread stripping. The invention further provides for a boss that can be used with larger hole-saws and includes notches that accommodate driving pains extending on the side of the boss and where appropriate into the driving apertures. | 09-30-2010 |
20100322730 | Hole Saw Assembly - The present invention relates to a hole-saw assembly ( | 12-23-2010 |
Kym John Keightley, South Australia AU
Patent application number | Description | Published |
---|---|---|
20080260480 | Hole Saw Assembly - The present invention relates to a hole-saw assembly ( | 10-23-2008 |
Leo P. Keightley, Waltham, MA US
Patent application number | Description | Published |
---|---|---|
20110004090 | SHIELDED ELECTRODE CONNECTOR - An ECG lead set is described which is shielded against electrostatic charge hazards. An electrical shield ( | 01-06-2011 |