Patent application number | Description | Published |
20100260567 | Rotary Tool, in Particular a Drill - In order to provide a rotary tool, in particular a drill, with a long service life together with high-quality drill holes, particularly in the case of through bores, the invention provides a cutting head which extends along a rotational axis and has a plurality of main cutting edges which extend radially outwards and each end at a cutting corner having a corner bevel, wherein the corner bevels are of differing designs, specifically in the form of a roughing bevel and in the form of a finishing bevel. | 10-14-2010 |
20110158757 | ROTARY CUTTING TOOL HAVING SEALED MARGINS AND METHOD OF MAKING SAME - A rotary cutting tool includes a generally cylindrical body having a first end, a second end and a longitudinal axis therebetween. A mounting portion is disposed about the first end, a head portion having an outer diameter is disposed about the second end, and a body relief portion having an outer diameter less than the head portion is disposed therebetween. The head portion is structured to engage and cut a workpiece. A number of flutes extend from the second end of the cylindrical body along the head portion and along at least a portion of the body relief portion. The head portion includes a number of margin relief surfaces, each disposed between adjacent flutes and inset a distance from the outer diameter of the head portion and extending from the second end of the cylindrical body and terminating at a margin seal within the head portion. | 06-30-2011 |
20110318128 | DRILL TIP AND DRILLING TOOL HAVING A DRILL TIP - The invention relates to a drill tip ( | 12-29-2011 |
20130004253 | DRILLING/REAMING TOOL - A drilling/reaming tool includes a basic body which extends in a longitudinal direction. The basic body includes at least one end-side drilling major cutting edge, a main flute which is assigned to said drilling major cutting edge and is wound at a first helix angle, and a plurality of reaming cutting edges which are arranged circumferentially on the basic body and have in each case one reamer flute which is assigned to the respective reaming cutting edge and is wound at a second helix angle. The reaming cutting edges adjoin the at least one major cutting edge directly in the longitudinal direction. Each reamer flute is merged into the main flute. | 01-03-2013 |
20130121778 | MANUFACTURING OF HOLEMAKING TOOLS - A process for producing a tool having a main body which extends in a longitudinal direction and at least one blade for machining a workpiece includes providing a base coating on the tool; grinding the at least one blade in a manner that removes the base coating in the region of the at least one blade; and providing a second, fine coating, to the at least one ground blade. | 05-16-2013 |
20140017022 | COUPLING POINT FOR A MODULAR ROTARY TOOL AND TOOL HEAD CARRIER FOR A MODULAR ROTARY TOOL - A coupling point for a modular rotary which extends in an axial direction. The coupling point includes a first coupling part disposed on a tool head and a second coupling part disposed on a carrier. The coupling parts can be coupled to one another by bidirectional rotation with the formation of an interference fit which acts in the radial direction. Each coupling part includes two coupling faces which lie opposite one another and have contact regions in which the interference fit is formed. In the first coupling part, at least one of the coupling faces has at least two contact regions which are spaced apart from one another in the circumferential direction, and, to this end, at least one first clearance portion is formed between the contact regions, in which clearance portion the two coupling parts do not bear against one another in the coupled state. | 01-16-2014 |
20140308086 | DRILL HEAD - A tool head includes a main body having a nominal diameter, a face end center formed on the main body, and at least two major cutting edges which each run radially outward from and adjoin the face end center. The face end center is formed by a cone of circular cross-sectional area, which cone extends from a cone apex through to a cone base. | 10-16-2014 |
20150071718 | METHOD TO PRODUCE A RADIAL RUN-OUT TOOL AS WELL AS A RADIAL RUN-OUT TOOL - The radial run-out tool ( | 03-12-2015 |
Patent application number | Description | Published |
20100272780 | CELL LINES THAT PRODUCE PROSTAGLANDIN F2 ALPHA (PGF2a) AND USES THEREOF - The invention provides cells and cell lines the are genetically modified to express the hCox-2 enzyme, which, in turn, results in the upregulation of prostaglandin F2 alpha (PGF2a) production. The invention also provides encapsulated cell therapy devices containing such cells or cell lines that are capable of delivering PGF2a as well as methods of using these devices to deliver PGF2a to the eye and to treat ophthalmic disorders in patients suffering therefrom. | 10-28-2010 |
20110111008 | Use of PEDF in an Encapsulated Cell-Based Delivery System - The invention relates to a device for delivery of pigment epithelium derived factor (PEDF) to the eye utilizing encapsulated PEDF-secreting cells and related methods for the treatment and prevention of ophthalmic diseases and disorders. | 05-12-2011 |
20110236457 | Micronized Device for the Delivery of Biologically Active Molecules and Methods of Use Thereof - The invention provides micronized encapsulated cell therapy devices that are capable of delivering a biologically active molecule to the eye. Also provided are methods of using the same to deliver biologically active molecules to the eye and to treat ophthalmic disorders in patients suffering there from. | 09-29-2011 |
20150024024 | Cell Lines That Produce Prostaglandin F2 Alpha (PGF2A) And Uses Thereof - Cells and cell lines that are genetically modified to express the hCox-2 enzyme, which results in the upregulation of prostaglandin F2 alpha (PGF2a) on the cells have been obtained. Encapsulated cell therapy devices containing such cells or cell lines that are capable of delivering PGF2a, as well as methods of using these devices to deliver PGF2a to the eye and to treat ophthalmic disorders in patients suffering therefrom are also described. | 01-22-2015 |
Patent application number | Description | Published |
20080254078 | Chitosan-Based Particles - The present invention provides a new binary system of hydrophilic nanoparticles and microparticles, using chitosan and polyanionic polysaccharides carrying carboxymethyl groups, sulfate groups or carboxy plus sulfate groups. | 10-16-2008 |
20090117195 | Hydrophilic Particles Based on Cationic Chitosan Derivatives - The present invention provides new nanoparticles and microparticles of hydrophilic character, prepared out of a cationic chitosan derivative and a polyanionic polymer. | 05-07-2009 |
20110244044 | COMPOUND, MEDICAMENT, VACCINE COMPOSITION AND NANOCAPSULES - The present invention relates to a compound comprising a polyelectrolyte and, covalently linked thereto, an immunological adjuvant and/or cell targeting ligand, wherein the covalently linked entity can have both adjuvant and cell targeting characteristics. The compound is used in the preparation of hydrophilic vaccine nanoparticles, which preferably have an antigenic compound or therapeutic agent, or genetic information encoding such compounds or agents entrapped in their matrix, or covalently linked to their surfaces. Vaccine compositions comprising the particles of the invention are advantageous, because a strong and long-lasting immune response is obtained following administration of a single dose. In a preferred embodiment, the polyelectrolyte of the compound is an anionic polymer, and the particle comprises a matrix comprising chitosan. | 10-06-2011 |