Kaohsiung Medical University
Kaohsiung Medical University, Kaohsiung City TW
Patent application number | Description | Published |
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20130072694 | 18 -GLYCYRRHETINIC ACID DERIVATIVES AND SYNTHETIC METHOD THEREOF - The present invention provides a chemical compound having the structure being one selected from a group consisting of | 03-21-2013 |
20130089601 | METHOD FOR TREATING ATHEROSCLEROSIS - The invention provides a method for treating atherosclerosis in a subject in need thereof, including administering an effective amount of microRNA-195 to the subject in need thereof. The microRNA-195 may be packaged in a pharmaceutically acceptable carrier. Moreover, the pharmaceutically acceptable carrier may includes a liposome, lipid particle or viral vector. | 04-11-2013 |
20130177976 | COMBINATION OF CATIONIC POLYMERS AND POLYSACCHARIDES NANOPARTICLES AS A GENE CARRIER - The present invention discloses a gene carrier and the preparation method thereof. The chondroitin sulfate (CS) is reacted with methacrylic anhydride (MA) to form a chondroitin sulfate-methacrylate (CSMA), which is further covalently bound with 2-(dimethylamino)ethyl methacrylate (DMAEMA) to form the “CM-DM” gene carrier. The novel nonviral and lower cytotoxic gene delivery vector/carrier with the sugar functionality reduced the cytotoxicity of poly(2-dimethylaminoethyl methacrylate) (PDMAEMA), and can successfully deliver plasmid DNA to cancer cells via the caveolae-mediated and CD44-mediated endocytosis mechanisms. | 07-11-2013 |
Kaohsiung Medical University, Kaohsiung TW
Patent application number | Description | Published |
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20130137597 | Microrna-based method for anti-colorectal cancer effects and prognosis of colorectal cancer - The present invention discloses a method of providing anti-oncogenic effects in a subject suffered from colorectal cancer. The present invention also discloses a method for screening an anti-colorectal cancer agent. The present invention further discloses a method of determining the prognosis of a subject with colorectal cancer. | 05-30-2013 |
20130177917 | NUCLEOTIDE SEQUENCE FOR COLUMBIDAE GENDER AND NUCLEOTIDE PRIMER PAIR FOR COLUMBIDAE GENDER - The invention provides a nucleotide sequence for Columbidae gender identification, including SEQ ID NO: 9 or a complementary sequence thereof, and also provides a nucleotide primer pair for Columbidae gender identification, including a first primer pair of a first primer designed within the region of the SEQ ID NO: 9 or a complementary sequence thereof, and a P2 primer (SEQ ID NO: 1) or a complementary sequence thereof. | 07-11-2013 |
Kaohsiung Medical University US
Patent application number | Description | Published |
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20130210134 | Hybrid Superparamagnetic Iron Oxide Nanoparticles and Polyethylenimine as a Magnetocomplex for Gene Transfection - Disclosed are the nanoparticle and the method for the same, and the preparing method includes steps of mixing polyethylenimine (PEI) with the poly(acrylic acid)-bound iron oxide (PAAIO) to form a PEI-PAAIO polyelectrolyte complex (PEC) and mixing the PEI-PAAIO PEC with genetic material such as plasmid DNA to form the PEI-PAAIO/pDNA magnetic nanoparticle. The PEI-PAAIO/pDNA magnetoplex is highly water dispersible and suitable for long term storage, shows superparamagnetism, low cytotoxicity, high stability and nice transfection efficiency, and thus the PEI-PAAIO PEC can replace PEI as a non-viral gene vector. | 08-15-2013 |