Jonathan Michael
Jonathan Michael Benns, Salt Lake City, UT US
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20140017177 | SILENE CAPENSIS FOR INHIBITING CRAVINGS - A composition can include: silene extract; and a carrier having the silene extract. The composition can include an active agent, such as a pharmaceutical or a nutraceutical. The composition can be in a form of a solid, paste, gel, gum, or combination thereof. The carrier can facilitate retention in the mouth, chewing, sucking, holding in the lip next to the gums, or other non-liquid format. A method can provide an alternative to an activity that reduces desire to perform the activity, the method can include: administering to a subject in need thereof the composition having silene. The method can include administering the composition in an effective amount to treat one or more of smoking dependence, tobacco withdrawal symptoms, and tobacco dependence in the subject, wherein the activity is smoking. | 01-16-2014 |
Jonathan Michael Chergurovich, Collegeville, PA US
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20140100213 | TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS - This invention relates to the use of triazolone derivatives for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of triazolones in the treatment of cancer. | 04-10-2014 |
Jonathan Michael Ghergurovich, Collegeville, PA US
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20140194415 | FATTY ACID SYNTHASE INHIBITORS - This invention relates to spirocyclic piperidines according to Formula (I) and the use of spirocyclic piperidines for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of spirocyclic piperidines in the treatment of cancer. | 07-10-2014 |
Jonathan Michael Gloag, Cambridge GB
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20130039685 | Motor Control System - A motor control system includes a motor having an associated rotary position encoder, and a controller for controlling the operation of the motor, wherein the motor is switchable between a position control mode and a torque control mode. | 02-14-2013 |
Jonathan Michael Gray, Hermosa Beach, CA US
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20150261580 | PLANNER FOR CLUSTER MANAGEMENT SYSTEM - A processing device receives a starting cluster layout for a first cluster, a target cluster layout for the first cluster, and a cluster management operation for creating or modifying the first cluster. The processing device determines a plurality of node level tasks to transition the first cluster from the starting cluster layout to the target cluster layout, determines dependencies between the plurality of node level tasks, and determines an order for the plurality of node level tasks based on the cluster management operation and the dependencies. The processing device then creates an execution plan that divides the cluster management operation into the plurality of node level tasks in the determined order. | 09-17-2015 |
20150264119 | SOLVER FOR CLUSTER MANAGEMENT SYSTEM - A processing device receives a first cluster management operation request, wherein the first cluster management operation request is for a deployment operation of a first cluster and comprises a cluster template, a specified number of nodes to deploy and a configuration. The processing device determines a plurality of constraints from at least one of the cluster template or the configuration. The processing device deterministically solves for and outputs a first cluster layout comprising the specified number of nodes, each of the specified number of nodes comprising a hardware type, an image type and one or more services, wherein the first cluster layout satisfies the plurality of constraints. | 09-17-2015 |
20150264122 | PROVISIONER FOR CLUSTER MANAGEMENT SYSTEM - A processing device executing a provisioner requests a node level task from a server. The processing device receives an assignment of a first node level task, wherein the first node level task is associated with a cluster management operation for a first cluster. The processing device determines a first plugin capable of performing the first node level task from a plurality of plugins, wherein each of the plurality of plugins comprises a self-contained program for performing a specific set of node level tasks. The processing device performs the first node level task by the first plugin, wherein the first node level task is an operation on a remote target host that does not include software associated with the provisioner. The processing device reports a result of the node level task to the server. | 09-17-2015 |
Jonathan Michael Kinnick, Ontario, CA US
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20150032235 | SYSTEMS AND METHODS FOR AUTOMATED ANALYSIS OF FITNESS DATA - Systems and methods are provided for processing and analyzing workout or other fitness data associated with a user. For example, a fitness analysis system may electronically receive workout data indicating performance of a user with respect to each of a number of different workouts completed by the user, where a given workout may include multiple movements. The workout data may be processed and analyzed to determine features or aspects of fitness or health that are relatively strong or weak for the given user by applying one or more rule sets and/or based on comparisons among a variety of the processed data. One or more user interfaces may then be generated providing graphical or other indications of fitness strengths or weaknesses determined by the fitness analysis system. | 01-29-2015 |
20150032236 | SYSTEMS AND METHODS FOR GENERATING A FITNESS REPORT - Systems and methods are provided for processing workout or other fitness data associated with a user and generating scores, reports and/or other analysis based on the processed data. For example, a fitness analysis system may electronically receive workout data indicating performance of a user with respect to each of a number of different workouts completed by the user, where a given workout may include multiple movements. A fitness category may be automatically assigned to a given workout by, for example, analyzing attributes of movements included in the workout. A category-based score may then be generated for the user for each of a number of different fitness categories, and an overall fitness score determined based at least in part on the generated category scores. | 01-29-2015 |
Jonathan Michael Krafcik, Mountain View, CA US
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20150066593 | DETERMINING A PRECISION FACTOR FOR A CONTENT SELECTION PARAMETER VALUE - Systems and methods for content selection with precision controls include receiving device identifier data from multiple sources. A machine learning model may be applied to the device identifier data and content selection parameter values may be predicted. Percentiles for the predicted content selection parameter values may be analyzed to determine precision factors for the predicted content selection parameter values. | 03-05-2015 |
20150066630 | CONTENT SELECTION WITH PRECISION CONTROLS - Systems and methods for content selection with precision controls include receiving a content selection parameter value and a degree of precision specified by a content provider. A content selection parameter value for a device identifier may be predicted using a predictive model. A precision factor may be associated with the predicted content selection parameter value. Content from the provider may be selected based on a comparison between the predicted selection parameter value and precision factor for the device identifier and the selection parameter value and degree of precision specified by the content provider. | 03-05-2015 |
Jonathan Michael Krafcik, Los Gatos, CA US
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20140032321 | VALUING AUDIENCE DATA - Systems, apparatus, and methods allow for revenue sharing between data providers and web page publishers. In one aspect, a computer-implemented method includes: receiving a request for alternative content based on a request for content; receiving user identifier data from at least one data provider; selecting at least one first alternative content from a first pool of alternative content that is contextually related to the requested content; determining a first cost of the at least one first alternative content; selecting, by at least one processing circuit, at least one second alternative content from the first pool, and from the second pool of alternative content that is related to the user identifier data; determining a second cost of the at least one second alternative content; and determining a pricing value of the user identifier data based on a difference between the second and the first costs. | 01-30-2014 |
Jonathan Michael Moore, Bristol GB
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20130142620 | METHOD OF POSITIONING A CONTROL SURFACE TO REDUCE HYSTERESIS - A method of determining the actual position of a control surface ( | 06-06-2013 |
Jonathan Michael Perez De Alderete, Carlisle, MA US
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20150297363 | Prosthetic Limb - A prosthetic limb includes a plurality of extendable segments configured to adjust the length of the prosthetic limb. Also included is a first end assembly operatively coupled to the plurality of extendable segments, wherein the first end assembly is radially adjustable to manipulate the thickness of the prosthetic limb. Further included is a second end assembly operatively coupled to the plurality of extendable segments, wherein the second end assembly is radially adjustable to manipulate the thickness of the prosthetic limb. | 10-22-2015 |
Jonathan Michael Salz, Taipei TW
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20150161110 | TECHNIQUES FOR A GENDER WEIGHTED PINYIN INPUT METHOD EDITOR - A computer-implemented technique can receive a first input from a user including one or more characters of a first language, which is a transliteration of a second language. The technique can determine a coefficient indicative of a gender of the recipient. The technique can determine and display potential translations of the first input to the second language based on the coefficient. The technique can receive a selection by the user of one of the potential translations to obtain a selected character. The technique can adjust the coefficient based on the selected character to obtain a modified coefficient. The technique can determine and display potential translations of second input from the user to the second language based on the modified coefficient. | 06-11-2015 |
Jonathan Michael Smith, Williamsport, PA US
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20140116964 | METHOD AND SYSTEM FOR DISPOSING OF DRILL CUTTINGS - A method and apparatus for disposing of drill cuttings includes collecting drilling mud from a wellbore, the drilling mud comprising liquid and solids, separating the liquid from the solids in a first separation step, separating the liquid from the solids in a second separation step, and transferring the solids to a container with a vacuum pump. | 05-01-2014 |
Jonathan Michael White, Laxey GB
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20130337132 | LIQUID HEATING APPARATUS - An infusion beverage making apparatus ( | 12-19-2013 |
20140233928 | FLOW HEATERS - A flow heater is provided including a heating element, a channel heated by said heating element for heating liquid flowing therethrough, and temperature sensing means in thermal communication with both the heating element and the channel so as to be sensitive to the temperature of the liquid in the channel and the temperature of the heating element. | 08-21-2014 |
Jonathan Michael Wojciak, San Diego, CA US
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20130261287 | ANTIBODY DESIGN USING ANTI-LIPID ANTIBODY CRYSTAL STRUCTURES - Methods for designing optimized antibodies, including optimized humanized or human antibodies, to target bioactive lipids are provided. These methods may be performed in silico and may be intended to enhance binding affinity of an antibody to its original target lipid, and/or to alter binding specificity. Antibodies produced by these methods are also provided, as are methods for using them. | 10-03-2013 |
Jonathan Michael Wojciak, Encinitas, CA US
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20100034814 | COMPOSITIONS AND METHODS FOR BINDING LYSOPHOSPHATIDIC ACID - Compositions and methods for making and using anti-LPA agents, for example, monoclonal antibodies, are described. Variable domain and complementarity determining region amino acid sequences of several monoclonal antibodies against LPA are disclosed, as is a consensus anti-LPA monoclonal antibody variable domain sequence. | 02-11-2010 |
20100292443 | Humanized platelet activating factor antibody design using anti-lipid antibody templates - Methods for designing a humanized antibody to platelet activating factor are provided. These methods may be performed in silico. | 11-18-2010 |
20110044990 | ANTIBODY DESIGN USING ANTI-LIPID ANTIBODY CRYSTAL STRUCTURES - The present invention provides crystalline forms of an anti-lipid antibody or fragment thereof, which may further comprise a lipid ligand of said antibody and/or salts, metals, or co-factors. Methods for making such crystals and co-crystals are provided. The lipid may be a bioactive lipid, including sphingolipids such as S1P. X-ray coordinates of such a crystal are provided, as are methods of using this information in antibody design or optimization. Methods for designing a humanized antibody to a lipid are provided. These methods may be performed in silico and may be intended to enhance binding affinity of an antibody to its original target lipid, and/or to alter binding specificity. Antibodies produced by these methods are also provided. | 02-24-2011 |
20110118443 | ANTIBODY DESIGN USING ANTI-LIPID ANTIBODY CRYSTAL STRUCTURES - Methods for designing optimized antibodies, including optimized humanized or human antibodies, to target bioactive lipids are provided. These methods may be performed in silico and may be intended to enhance binding affinity of an antibody to its original target lipid, and/or to alter binding specificity. Antibodies produced by these methods are also provided, as are methods for using them. | 05-19-2011 |
20110212088 | ANTI-PAF ANTIBODIES - Monoclonal antibodies to platelet activating factor (PAF) are described, along with methods for their production and use. Such antibodies can be formulated and used for therapeutic purposes, as well as for diagnosis and detection. | 09-01-2011 |
20120034631 | ANTI-LYSOPHOSPHOLIPID ANTIBODY DESIGN USING ANTIBODY STRUCTURES - The present invention provides crystalline forms of an anti-LPA antibody or fragment thereof, which may further comprise a lipid ligand of said antibody and/or salts, metals, or co-factors. Methods for making such crystals and co-crystals are provided, as are methods of using structural information in antibody design or optimization. Methods for designing a humanized antibody to a lipid are provided. These methods may be performed in silico and may be intended to enhance binding affinity of an antibody to its original target lipid, and/or to alter binding specificity. Optimized variant anti-LPA antibodies are also provided. | 02-09-2012 |
20130344087 | COMBINATIONS OF ANTI-S1P ANTIBODIES AND SHPINGOLIPID PATHWAY INHIBITORS - Methods for administering combinations of compositions comprising anti-S1P antibodies or antibody fragments and modulators of sphingolipid metabolic pathway enzymes are described. Such methods allow aberrant or undesirable levels of S1P to be reduced in patients known or suspected to have a disease or disorder correlated with aberrant S1P levels, and thus will be useful in treating such diseases and disorders. | 12-26-2013 |
20150152172 | COMPOSITIONS AND METHODS FOR BINDING CYSTEINYL LEUKOTRIENES (CYSLTS) FOR TREATMENT OF DISEASE - Methods are provided for using antibodies that bind one or more cysteinyl leukotrienes (cysLTs) for treatment of diseases, including inflammatory diseases and asthma, associated with aberrant levels of one or more cysLTs. Anti-cysLT antibodies and antigen-binding antibody fragments, and compositions containing such antibodies and antibody fragments, are also provided. | 06-04-2015 |