John Stephen
John Stephen Almasi, Springville, NY US
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20150321261 | AIR EJECTOR FOR LATHE - A part ejector is shown and described wherein a machined part in a CNC lathe is ejected from a spindle of the lathe by means of an air pressure differential. The part ejector includes inner and outer tubes that are coupled to, and aligned with a spindle collet. Machined parts are received within the inner tube and a pin tool moves a pin into the inner tube to pneumatically seal the inner tube and push a machined part past one or more air ports that pneumatically connect the inner tube with an air channel located between the inner and outer tubes. Pressurized air is applied to the air channel and the pin is partially retracted to uncover the air ports thus allowing the pressurized air to enter the inner tube and eject the machined part out. | 11-12-2015 |
John Stephen Baross, Aberdeenshire GB
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20080277123 | Offshore Vessel Mooring and Riser Inboarding System - There is disclosed an offshore vessel mooring and riser inboarding system ( | 11-13-2008 |
John Stephen Bratt, Newcastle-Under-Lyme GB
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20120032374 | MOULD FOR PRODUCING BONE CEMENT PELLETS - A mould for producing bone cement pellets, the mould comprising a plurality of complementarily shaped mould segments which fit together to make a composite mould having a plurality of individual mould cavities and one or more injection ports for feeding, in use, hardenable bone cement to said mould segments and said plurality of individual mould cavities. | 02-09-2012 |
John Stephen Bubulka, Westchester, IL US
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20090230760 | FABRICATED VEHICLE AXLE - A fabricated vehicle axle is provided with a single piece main body having an inverted U-shaped configuration. The ends of the main body are curved upwardly to define a pair of gooseneck portions. A first king pin fixture having a king pin bore is secured to one of the gooseneck portions, while a second king pin fixture having a king pin bore is secured to the other gooseneck portion. A bottom plate is secured to the main body and has ends extending beyond the gooseneck portions to provide seats for the king pin fixtures. | 09-17-2009 |
20120056469 | FABRICATED VEHICLE AXLE - A fabricated vehicle axle is provided with a main body defined by the combination of a channel having an inverted U-shaped configuration and a bottom plate. The ends of the main body are curved upwardly to define a pair of gooseneck portions. Axle head sections are formed at the ends of the axle and are closed off by end extensions extending from the front and rear walls of the channel and a cover flap extension extending from the top wall of the channel. A head plate is inserted within the space between the cover flap and the top edges of the end extensions. King pin bolt holes are machined at each axle head section into the cover flaps, head plates and each end of the bottom plate to permit a king pin to be installed therein. | 03-08-2012 |
John Stephen Cox, Stafford GB
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20160029883 | EYE TRACKING CALIBRATION - Method, system and apparatus for calibrating an eye tracker comprising presenting a subject with a visual target. Detemiining a physical arrangement in space of the subject. Obtaining an eye measurement of the subject. Storing a record of the subject's physical arrangement in space and data derived from the eye measurement of the subject, associated with the visual target presented to the subject. Repeating for one or more further different visual targets. | 02-04-2016 |
John Stephen Danaher, Brooklyn, NY US
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20130007118 | COLLABORATIVE ONLINE SPREADSHEET APPLICATION - A distributed spreadsheet application executes at a server and a client in a network. The networked spreadsheet application can generally be used without requiring a user to install any specific spreadsheet software prior to using the application. In one implementation, the spreadsheet application may include a client engine that executes within browser programs of a plurality of client computing devices and server logic. The server logic may be configured to distribute the client engines to the plurality of client computing devices of the spreadsheet application when requested through the browser programs of each of the plurality of client computing devices. The server logic synchronizes a single spreadsheet document that is simultaneously open at the plurality of client computing devices. | 01-03-2013 |
20130254270 | COLLABORATIVE ONLINE SPREADSHEET APPLICATION - A distributed spreadsheet application executes at a server and a client in a network. The networked spreadsheet application can generally be used without requiring a user to install any specific spreadsheet software prior to using the application. In one implementation, the spreadsheet application may include a client engine that executes within browser programs of a plurality of client computing devices and server logic. The server logic may be configured to distribute the client engines to the plurality of client computing devices of the spreadsheet application when requested through the browser programs of each of the plurality of client computing devices. The server logic synchronizes a single spreadsheet document that is simultaneously open at the plurality of client computing devices. | 09-26-2013 |
20130254644 | COLLABORATIVE ONLINE SPREADSHEET APPLICATION - A distributed spreadsheet application executes at a server and a client in a network. The networked spreadsheet application can generally be used without requiring a user to install any specific spreadsheet software prior to using the application. In one implementation, the spreadsheet application may include a client engine that executes within browser programs of a plurality of client computing devices and server logic. The server logic may be configured to distribute the client engines to the plurality of client computing devices of the spreadsheet application when requested through the browser programs of each of the plurality of client computing devices. The server logic synchronizes a single spreadsheet document that is simultaneously open at the plurality of client computing devices. | 09-26-2013 |
20130262975 | COLLABORATIVE ONLINE SPREADSHEET APPLICATION - A distributed spreadsheet application executes at a server and a client in a network. The networked spreadsheet application can generally be used without requiring a user to install any specific spreadsheet software prior to using the application. In one implementation, the spreadsheet application may include a client engine that executes within browser programs of a plurality of client computing devices and server logic. The server logic may be configured to distribute the client engines to the plurality of client computing devices of the spreadsheet application when requested through the browser programs of each of the plurality of client computing devices. The server logic synchronizes a single spreadsheet document that is simultaneously open at the plurality of client computing devices. | 10-03-2013 |
20150212980 | CONVERTING SPREADSHEET APPLICATIONS TO WEB-BASED APPLICATIONS - A networked version of a spreadsheet application can be automatically created from an existing “conventional” spreadsheet. In one implementation, a server may obtain a data file, where the data file represents a networked version of a spreadsheet application that was converted from the “conventional” application and the data file defines characteristics of the networked version of the spreadsheet application including logic and interactivity attributes of cells in the networked version of the spreadsheet application. A remote request may be received from a client to access the networked version of the spreadsheet application. In response, the server may transmit a document to the client that represents a portion of the networked version of the spreadsheet application that the interactivity attributes specify as being displayable to the client. | 07-30-2015 |
John Stephen Derov, Lowell, MA US
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20120274525 | Steering Radio Frequency Beams Using Negative Index Metamaterial Lenses - A method and apparatus are present for steering a radio frequency beam. The radio frequency beam is emitted from an array of antenna elements at a first angle into a lens at a location for the lens. The first angle of the radio frequency beam is changed to a second angle when the radio frequency beam exits the lens. The second angle changes when the location at which the radio frequency beam enters the lens changes. The second angle of the radio frequency beam is changed to a third angle when the radio frequency beam with the second angle passes through a negative index metamaterial lens located over the lens. | 11-01-2012 |
John Stephen Drewery, Santa Clara, CA US
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20090266707 | Pad-assisted electropolishing - Pad-assisted electropolishing of the substrate is conducted by performing anodic dissolution of metal at a first portion of the substrate and simultaneously mechanically buffing a second portion of the substrate with a buffing pad. Anodic dissolution includes forming a thin liquid layer of electropolishing liquid between the anodic substrate and a cathodic electropolishing head. The location of electrical contacts between the substrate and power supply allow peripheral edge regions of the substrate to be mechanically buffed with the pad. Preferably, a substrate is further planararized using an isotropic material-removal technique. An apparatus includes an electropolishing head that is movable to a position proximate to a first portion of a substrate to form a thin gap, and a buffing pad that mechanically buffs a second portion of the substrate using minimal pressure. | 10-29-2009 |
20090277801 | Photoresist-free metal deposition - Selectively accelerated or selectively inhibited metal deposition is performed to form metal structures of an electronic device. A desired pattern of an accelerator or of an inhibitor is applied to the substrate; for example, by stamping the substrate with a patterned stamp or spraying a solution using an inkjet printer. In other embodiments, a global layer of accelerator or inhibitor is applied to a substrate and selectively modified in a desired pattern. Thereafter, selective metal deposition is performed. | 11-12-2009 |
20090277802 | Pad-assisted electropolishing - Pad-assisted electropolishing of the substrate is conducted by performing anodic dissolution of metal at a first portion of the substrate and simultaneously mechanically buffing a second portion of the substrate with a buffing pad. Anodic dissolution includes forming a thin liquid layer of electropolishing liquid between the anodic substrate and a cathodic electropolishing head. The location of electrical contacts between the substrate and power supply allow peripheral edge regions of the substrate to be mechanically buffed with the pad. Preferably, a substrate is further planararized using an isotropic material-removal technique. An apparatus includes an electropolishing head that is movable to a position proximate to a first portion of a substrate to form a thin gap, and a buffing pad that mechanically buffs a second portion of the substrate using minimal pressure. | 11-12-2009 |
20090280243 | Photoresist-free metal deposition - Selectively accelerated or selectively inhibited metal deposition is performed to form metal structures of an electronic device. A desired pattern of an accelerator or of an inhibitor is applied to the substrate; for example, by stamping the substrate with a patterned stamp or spraying a solution using an inkjet printer. In other embodiments, a global layer of accelerator or inhibitor is applied to a substrate and selectively modified in a desired pattern. Thereafter, selective metal deposition is performed. | 11-12-2009 |
20140014522 | PHOTORESIST-FREE METAL DEPOSITION - Selectively accelerated or selectively inhibited metal deposition is performed to form metal structures of an electronic device. A desired pattern of an accelerator or of an inhibitor is applied to the substrate; for example, by stamping the substrate with a patterned stamp or spraying a solution using an inkjet printer. In other embodiments, a global layer of accelerator or inhibitor is applied to a substrate and selectively modified in a desired pattern. Thereafter, selective metal deposition is performed. | 01-16-2014 |
John Stephen Eadicicco, West Chester, OH US
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20100035933 | Kits, Recloseable Containers, Blanks And Methods Of Treatment - Kits include a recloseable container and an inner container housed within the recloseable container. The recloseable container can include a front wall and a front flap operable to transition between an open position and a closed position, wherein the front flap releasably engages the front wall when in the closed position. Methods of treatment which utilize the kits are also disclosed. Blanks for the recloseable container are also disclosed. | 02-11-2010 |
20140155435 | Kit for Treatment of Upper Gastrointestinal Tract Conditions - Disclosed herein are kits useful for facilitating compliance with a treatment regimen. In one embodiment, the kits are useful for compliance with a defined method of treatment which utilizes a composition comprising a gastric acid secretion inhibitor. In an alternative or additional embodiment, the kits comprise an outer container and at least two inner containers, wherein each of the inner containers comprise, independently, a plurality of unit doses of a composition comprising a therapeutically effective amount of a gastric acid secretion inhibitor. | 06-05-2014 |
John Stephen Godbehere, Ochlocknee, GA US
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20130178364 | Odor mitigating fumigant composition - An odor mitigating agricultural fumigant includes a mixture of DMDS and 1,3-dichloropropene, which is added to the mixture as an ingredient of Telone® or Telone II®. This mixture significantly reduces the Mercaptan-like odor that normally accompanies Paladin® (DMDS) and Paladin® based mixtures. | 07-11-2013 |
John Stephen Haggas, West Yorkshire GB
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20130053984 | PROSTHETIC APPARATUS AND ARTIFICIAL JOINT - An artificial joint with two degrees of freedom has two rotary motors that move the joint in one degree of freedom when operated in respective senses of rotation and move the joint in the other degree of freedom when one of the motors is reversed. The movement depends on balancing the operation of the motors, which are controlled by a microprocessor. Sensors on the joint are connected to the microprocessor in a closed-loop feedback. A prosthetic device includes a tendon received in one end of a slot in a movable member, whereby movement of the tendon moves the movable member. A prosthesis has two parts moveable relative to one another, an actuator, and a user control. A transducer connected to the control and the actuator provides signals indicating movement effected by the actuator. A prosthesis cover includes a silicone laminate and a reinforcing liner. | 02-28-2013 |
John Stephen Hill, Solvang, CA US
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20140314667 | METHODS OF TREATING EPIDERMAL GROWTH FACTOR DELETION MUTANT VIII RELATED DISORDERS - The present invention relates to methods of treating treating epidermal growth factor deletion mutant vIII (EGFRvIII) related disorders, such as glioblastoma or anaplastic astrocyte tumors, using antigen binding proteins, including antibodies against EGFRvIII conjugated to a drug. Diagnostic and therapeutic formulations of such antibodies and drug conjugates thereof are also provided. | 10-23-2014 |
John Stephen Hiltpold, Sugar Land, TX US
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20100084588 | Deepwater Hydraulic Control System - A hydraulic control system and method utilizing a retrievable control pod for the actuation of subsea blowout preventer stacks are disclosed. In one embodiment, the hydraulic control system comprises a subsea hydraulic umbilical line, a lower marine riser package having a hydraulic receptacle, a hydraulic control pod having a hydraulic connector for hydraulically mating with the hydraulic receptacle, at least one pod umbilical hydraulic connector hydraulically connected through umbilical connector piping to the hydraulic control pod, and at least one lower marine riser package umbilical hydraulic connector for hydraulically mating with the pod umbilical hydraulic connector and the subsea hydraulic umbilical line. | 04-08-2010 |
20100155073 | RETRIEVABLE HYDRAULIC SUBSEA BOP CONTROL POD - Systems and methods for improved hydraulic control systems for actuation of subsea equipment in deep water are disclosed. The hydraulic control system relies on smaller fluid flow associated with a hydraulic pressure pulse to actuate the small volume actuation control valve. In one embodiment, the system includes small diameter control umbilical hoses and pilot-operated valves with low actuation volumes. Particularly, a hydraulic control system for reducing the signal time to a subsea blowout preventer in water depth up to and greater than about 5000 feet. Some embodiments comprise a valve arrangement which hydraulically actuate one side of a hydraulic control function, while simultaneously evacuating the opposing circuit both at the seabed and at the surface. Some embodiments comprise an umbilical hose located proximate the center of an umbilical bundle. Preferably, the umbilical hose has a plurality of layers of reinforcing fibers which increase with the diameter of the reinforcement layer. | 06-24-2010 |
John Stephen Mysak, Rochester, MN US
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20140255004 | AUTOMATICALLY DETERMINING AND TAGGING INTENT OF SKIPPED STREAMING AND MEDIA CONTENT FOR COLLABORATIVE REUSE - A method, system, and computer program product for bypassing as portion of content of a media. A history of skipped sections for a media is accumulated. Each portion of skipped content is detected during a display of the media. A reason is automatically determined for each portion of media content that is skipped based on a set of predefined criteria and resulting in a measured value for each portion of skipped content. Each portion of skipped content is tagged with the associated measured value. Information associated with the tagged portions of skipped content is shared across a social network for collaborative reuse. A determination is also made whether or not the previously skipped portion or media content exceeds a predetermined user display threshold. Responsive to a user-configurable policy for bypassing content, the content of the media is automatically displayed on a user device and content exceeding the predetermined display threshold is skipped. | 09-11-2014 |
John Stephen Peanasky, Big Flats, NY US
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20120301914 | High Resolution Label-Free Sensor - An optical sensor for label-independent detection, having improved spatial resolution and reduced angular sensitivity, the sensor including: | 11-29-2012 |
20130101596 | DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS - The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, HUMIRA (Adalimumab). | 04-25-2013 |
20130171456 | Glass Articles With Low-Friction Coatings - Low-friction coatings and glass articles with low-friction coatings are disclosed. According to one embodiment, a coated glass article may include a glass body comprising a first surface and a low-friction coating positioned on at least a portion of the first surface of the glass body. The low-friction coating may include a polymer chemical composition. The coated glass article may be thermally stable at a temperature of at least about 260° C. for 30 minutes. A light transmission through the coated glass article may be greater than or equal to about 55% of a light transmission through an uncoated glass article for wavelengths from about 400 nm to about 700 nm. The low-friction coating may have a mass loss of less than about 5% of its mass when heated from a temperature of 150° C. to 350° C. at a ramp rate of about 10° C./minute. | 07-04-2013 |
20130196094 | DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS - The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, NEUPOGEN (filgrastim), NEULASTA (pegfilgrastim), EPOGEN (epoetin alfa) or ENBREL (etanercept). | 08-01-2013 |
20130196095 | DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS - The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, LEVEMIR, NOVOLOG, NOVOLIN 70-30, NOVOLIN R, NOVOLIN N, NOVOLOG MIX 70-30 and NOVOLIN L. | 08-01-2013 |
20130196096 | DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS - The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, PROCRIT (epoetin alfa), REMICADE (Infliximab) or DORIBAX (doripenem). | 08-01-2013 |
20130196097 | DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS - The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, LANTUS (insulin glargine [rDNA]), LOVENOX (Enoxaparin), PENTACT-HIB ( | 08-01-2013 |
20130202823 | DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS - The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, RITUXAN (rituximab), AVASTIN (Bevacizumab), LUCENTIS (Ranibizumab) or HERCEPTIN (trastuzumab). | 08-08-2013 |
20130213848 | DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS - The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, HUMALOG (insulin lispro), HUMALOG MIX 75-25 (insulin lispro), HUMALOG MIX 50-50 (insulin lispro), HUMILIN 70-30 (insulin), HUMILIN N (insulin), HUMULIN R (insulin) or GEMZAR (gemcitabine). | 08-22-2013 |
20130216742 | DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS - The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient. | 08-22-2013 |
20130224407 | Glass Articles With Low-Friction Coatings - Low-friction coatings and glass articles with low-friction coatings are disclosed. According to one embodiment, a coated glass article may include a glass body comprising a first surface and a low-friction coating positioned on at least a portion of the first surface of the glass body. The low-friction coating may include a polymer chemical composition. The coated glass article may be thermally stable at a temperature of at least about 260° C. for 30 minutes. A light transmission through the coated glass article may be greater than or equal to about 55% of a light transmission through an uncoated glass article for wavelengths from about 400 nm to about 700 nm. The low-friction coating may have a mass loss of less than about 5% of its mass when heated from a temperature of 150° C. to 350° C. at a ramp rate of about 10° C./minute. | 08-29-2013 |
20140001076 | DELAMINATION RESISTANT GLASS CONTAINERS WITH HEAT-TOLERANT COATINGS | 01-02-2014 |
20140034544 | STRENGTHENED BOROSILICATE GLASS CONTAINERS WITH IMPROVED DAMAGE TOLERANCE - According to one embodiment, a glass container may include a body formed from a Type I, Class B glass composition according to ASTM Standard E438-92. The body may have an inner surface, an outer surface and a wall thickness extending between the outer surface and the inner surface. The body may also include a compressively stressed layer extending into the wall thickness from at least one of the outer surface and the inner surface. A lubricous coating may be positioned on at least a portion of the outer surface of the body, wherein the outer surface of the body with the lubricous coating has a coefficient of friction less than or equal to 0.7. | 02-06-2014 |
20140069886 | DELAMINATION RESISTANT GLASS CONTAINERS WITH HEAT-TOLERANT COATINGS - Delamination resistant glass containers with heat-tolerant coatings are disclosed. In one embodiment, a glass container may include a glass body having an interior surface, an exterior surface and a wall thickness extending from the exterior surface to the interior surface. At least the interior surface of the glass body is delamination resistant. The glass container may further include a heat-tolerant coating positioned on at least a portion of the exterior surface of the glass body. The heat-tolerant coating may be thermally stable at temperatures greater than or equal to 260° C. for 30 minutes. | 03-13-2014 |
20140151320 | GLASS CONTAINERS WITH DELAMINATION RESISTANCE AND IMPROVED DAMAGE TOLERANCE - The glass containers described herein have at least two performance attributes selected from resistance to delamination, improved strength, and increased damage resistance. In one embodiment, a glass container may include a body having an inner surface, an outer surface and a wall thickness extending between the outer surface and the inner surface. At least the inner surface of the body may have a delamination factor less than or equal to 10. A tenacious inorganic coating may be positioned around at least a portion of the outer surface of the body. The outer surface of the body with the tenacious inorganic coating may have a coefficient of friction less than or equal to 0.7. | 06-05-2014 |
20140151321 | GLASS CONTAINERS WITH IMPROVED STRENGTH AND IMPROVED DAMAGE TOLERANCE - The glass containers described herein have at least two performance attributes selected from resistance to delamination, improved strength, and increased damage resistance. In one embodiment, a glass container may include a body having an inner surface, an outer surface and a wall thickness extending between the outer surface and the inner surface. A compressively stressed layer may extend from the outer surface of the body into the wall thickness. The compressively stressed layer may have a surface compressive stress greater than or equal to 150 MPa. A lubricous coating may be positioned around at least a portion of the outer surface of the body. The outer surface of the body with the lubricous coating may have a coefficient of friction less than or equal to 0.7. | 06-05-2014 |
20140151370 | STRENGTHENED GLASS CONTAINERS RESISTANT TO DELAMINATION AND DAMAGE - The glass containers described herein are resistant to delamination, have improved strength, and increased damage resistance. In one embodiment, a glass container may include a body having an inner surface, an outer surface and a wall thickness extending between the outer surface and the inner surface. At least the inner surface of the body may have a delamination factor less than or equal to 10. The body may also have a compressively stressed layer extending from the outer surface of the body into the wall thickness. The compressively stressed layer may have a surface compressive stress greater than or equal to 150 MPa. A lubricous coating may be positioned around at least a portion of the outer surface of the body, such that the outer surface of the body with the lubricous coating has a coefficient of friction less than or equal to 0.7. | 06-05-2014 |
20140151371 | GLASS CONTAINERS WITH DELAMINATION RESISTANCE AND IMPROVED STRENGTH - The glass containers described herein have at least two performance attributes selected from resistance to delamination, improved strength, and increased damage resistance. In one embodiment, a glass container with resistance to delamination and improved strength may include a body having an inner surface, an outer surface and a wall thickness extending between the outer surface and the inner surface. At least the inner surface of the body may have a delamination factor less than or equal to 10. The glass container may further include a compressively stressed layer extending from the outer surface of the body into the wall thickness. The compressively stressed layer may have a surface compressive stress greater than or equal to 150 MPa. | 06-05-2014 |
20140339122 | DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS - The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, VELCADE (bortezomib), STELARA (Ustekinumab), SIMPONI (golimumab), siltuximab, and AMG 403 (fulranumab). | 11-20-2014 |
20140339125 | DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS - The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, daclizumab (ZENAPAX®). | 11-20-2014 |
20140339126 | DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS - The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, PEDIARIX® (Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Hepatitis B (Recombinant) and Inactivated Poliovirus Vaccine), HAVRIX® (Hepatitis A Vaccine), ENGERIX-B® (Hepatitis B Vaccine (Recombinant)), TWINRIX® (Hepatitis A & Hepatitis B (Recombinant) Vaccine), EPERZAN® (albiglutide), MAGE-A3 Antigen-Specific Cancer Immunotherapeutic (astuprotimut-R), GSK2402968 (drisapersen), and HZ/su (herpes zoster vaccine). | 11-20-2014 |
20140341883 | DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS - The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, GAMMAGARD LIQUID (an immune globulin infusion (human)); ADVATE (Antihemophilic Factor (Recombinant), Plasma/Albumin-Free Method, (rAHF)); BAX 111 (vonicog alfa, or [618-threonine,709-aspartic acid] von Willebrand factor | 11-20-2014 |
20140341888 | DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS - The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, FORTEO® (recombinant human teriparatide), DULAGLUTIDE® (LY2189265), recombinant insulin glargine, RAMUCIRUMAB® (IMC-1121B), SOLANEZUMAB® (LY2062430), IXEKIZUMAB® (LY2439821), TABALUMAB® (LY2127399), NECITUMUMAB® (IMC-11F8), or CIXUTUMUMAB® (IMC-A12). | 11-20-2014 |
20140341889 | DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS - The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, Prolia® (denosumab), Xgeva® (denosumab), Aranesp® (darbepoetin alfa), AMG-145, romosozumab (AMG-785), ganitumab (AMG-479), trebananib (AMG-386), brodalumab (AMG-827), and rilotumumab (AMG-102). | 11-20-2014 |
20140341890 | DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS - The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, LUCENTIS® (ranibizumab), BEXSERO® (meningococcal group B vaccine [rDNA, component, adsorbed]), AIN457 (secukinumab) or RELAXIN® (serelaxin). | 11-20-2014 |
20140341891 | DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS - The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, LYXUMIA (lixisenatide), LEMTRADA (alemtuzumab), REGN727/SAR236553 (alirocumab), SAR2405550/BSI-201 (iniparib), OTAMIXABAN (otamixaban), SARILUMAB (sarilumab), LANTUS and LYXUMIA (insulin glargine and lixisenatide) or VISAMERIN/MULSEVO (semuloparin sodium). | 11-20-2014 |
20140341945 | DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS - The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, PREVNAR 13 (Pneumococcal 13-valent Conjugate Vaccine). | 11-20-2014 |
20140342979 | DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS - The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, Victoza (liraglutide), Tresiba (insulin degludec), Ryzodeg (insulin degludec/insulin aspart), IDegLira (liraglutide and insulin degludec), NovoSeven (recombinant human coagulation factor VIIa), NovoSeven RT (recombinant human coagulation factor VIIa), or Turoctocog alfa (third-generation recombinant coagulation factor VIII). | 11-20-2014 |
20150071913 | DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS - The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, PERJETA (pertuzumab), ACTEMRA (tocilizumab), KADCYLA (trastuzumab emtansine), MetMAb (onartuzumab), obinutuzumab, ocrelizumab or lebrikizumab. | 03-12-2015 |
20150085365 | LOW BIREFRINGENT SENSOR SUBSTRATE AND METHODS THEREOF - A resonant waveguide article, including: a polymeric substrate having at least one integral grating region, wherein the article has a low birefringence property of for example, from about 5 to 270 nm/cm, as defined herein. Also disclosed is a microplate including the resonant waveguide article, and an integral well plate bonded to the sensor article, as defined herein. Also disclosed are methods of making a sensor article, and a method of making and using the microplate including the sensor article, as defined herein. | 03-26-2015 |
20150329416 | GLASS ARTICLES WITH LOW-FRICTION COATINGS - Coated pharmaceutical packages are disclosed. In embodiments, a coated pharmaceutical package includes a glass body comprising a first surface. A low-friction coating may be positioned on at least a portion of the first surface of the glass body. The low-friction coating may include a polymer chemical composition. A light transmission through the coated pharmaceutical package may be greater than or equal to about 55% of a light transmission through an uncoated pharmaceutical package for wavelengths from about 400 nm to about 700 nm. The low-friction coating may have a mass loss of less than about 5% of its mass when heated from a temperature of 150° C. to 350° C. at a ramp rate of about 10° C./minute. | 11-19-2015 |
20150360999 | GLASS ARTICLES WITH LOW-FRICTION COATINGS - Coated pharmaceutical packages are disclosed. In embodiments, a coated pharmaceutical package may include a glass body comprising a first surface. A low-friction coating may be positioned on at least a portion of the first surface of the glass body. The low-friction coating may include a polymer chemical composition. The coated pharmaceutical package may be thermally stable at a temperature of at least about 260° C. for 30 minutes. The low-friction coating may have a mass loss of less than about 5% of its mass when heated from a temperature of 150° C. to 350° C. at a ramp rate of about 10° C./minute. | 12-17-2015 |
20150366756 | DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS - The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient. | 12-24-2015 |
20150374582 | DELAMINATION RESISTANT PHARMACEUTICAL GLASS CONTAINERS CONTAINING ACTIVE PHARMACEUTICAL INGREDIENTS - The present invention is based, at least in part, on the identification of a pharmaceutical container formed, at least in part, of a glass composition which exhibits a reduced propensity to delaminate, i.e., a reduced propensity to shed glass particulates. As a result, the presently claimed containers are particularly suited for storage of pharmaceutical compositions and, specifically, a pharmaceutical solution comprising a pharmaceutically active ingredient, for example, NEUPOGEN (filgrastim), NEULASTA (pegfilgrastim), EPOGEN (epoetin alfa) or ENBREL (etanercept). | 12-31-2015 |
John Stephen Pipis, Jr., Washington, IL US
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20090000581 | Variable valve actuator having self-centering pivotal piston - A variable valve actuator for a power system is provided. The variable valve actuator may have a hydraulic piston extendable to interrupt cyclical movement of an engine valve. The variable valve actuator may also have a pin member pivotally received by the hydraulic piston, and a retaining ring configured to axially align the pin member with the hydraulic piston as the hydraulic piston is retracted. | 01-01-2009 |
John Stephen Robinson, Cambridge GB
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20150232460 | NOVEL COMPOUNDS - The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, | 08-20-2015 |
John Stephen Robinson, Newhouse GB
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20100184761 | 6-PHENYL-1H-IMIDAZO[4,5-c]PYRIDINE-4-CARBONITRILE DERIVATIVES - The present invention relates to 6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives having the general Formula I | 07-22-2010 |
John Stephen Rosettie, Corning, NY US
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20080202364 | Means of attaining large screen print area with new squeegee design - An adjustable variable pressure squeegee for screen printing includes a holder having a compliant member coupled to a retainer member and a squeegee blade having an edge coupled to the retainer member. | 08-28-2008 |
20100132568 | Screen printing system and method of screen printing - A screen printing system includes a screen made of a porous material and an adjustable variable pressure squeegee having a squeegee blade. The squeegee blade has a first edge for contacting the screen and pushing an ink medium deposited on the screen through a print area of the screen. The squeegee blade has a second edge retained in a holder. The holder has a compliant member configured to distribute a downward force applied to a point on the compliant member along a length of the squeegee blade in order to maintain contact between the first edge and the screen along the length of the squeegee blade. | 06-03-2010 |
20100297534 | Seal Structures for Solid Oxide Fuel Cell Devices - Disclosed are seals and seal structures for use in electrochemical devices such as solid oxide fuel cell devices. Exemplary seal structures are configured such that at least a portion of the interface between the seal and electrolyte sheet deviates from planarity by extending either (i) upwardly and inwardly (ii) or downwardly and inwardly, toward the active portion of the electrolyte sheet surface where one or more device electrodes are deposited. By angling the seal portion of the electrolyte sheet, the sharpness of any resulting bends or deformations that may occur during use can be reduced, thus reducing the likelihood of any cracks forming in the typically high stress regions of the electrolyte sheet. Further, preferably at least a portion of the electrolyte sheet contacting the seal composition, the seal-electrolyte interface may deviate from planarity by at least 0.1 mm from the seal-electrolyte interface, where the deviation from planarity extends normal to the seal or inwardly toward the active surface region of the electrolyte sheet. Also disclosed are methods for manufacturing the inventive seal structures and electrochemical device assemblies comprising same. | 11-25-2010 |
20110041469 | Ceramic Radial Wall Flow Particulate Filter - The present disclosure relates to radial wall flow particulate filters comprised of ceramic material. The filters include a filter body that has a plurality of adjacent troughs circumferentially arranged around a longitudinal axis. | 02-24-2011 |
John Stephen Smith, Saajox, CA US
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20090109002 | ASSEMBLY COMPRISING A FUNCTIONAL DEVICE AND A RESONATOR AND METHOD OF MAKING SAME - A Radio Frequency Identification (RFID) device. The RFID device comprises an antenna assembly and a resonator assembly. The antenna assembly comprises a first substrate and an antenna element. The resonator assembly comprises a second substrate having an integrated circuit connected to a resonator loop. The first substrate and the second substrate are attached to one another. The integrated circuit electrically couples to the antenna element without a direct mechanical contact. | 04-30-2009 |
John Stephen Smith, Cupertino, CA US
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20150242037 | TRANSPARENT FORCE SENSOR WITH STRAIN RELIEF - A transparent force sensor for detecting an applied force on a surface of a device. The transparent force sensor includes a transparent force-sensitive film having an array of strain-relief features oriented along a first direction. The transparent force-sensitive film is formed from a transparent piezoelectric material that exhibits a substantially reduced net charge when strained along a primary direction. The force sensor also includes a display element disposed on one side of the transparent force-sensitive film. | 08-27-2015 |
John Stephen Smith, Berkeley, CA US
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20100075463 | Method and apparatus for fabricating self-assembling microstructures - A method and apparatus for assembling microstructures onto a substrate through fluid transport. The microstructures being shaped blocks self-align into recessed regions located on a substrate such that the microstructure becomes integral with the substrate. The improved method includes a step of transferring the shaped blocks into a fluid to create a slurry. Such slurry is then dispensed evenly or circulated over the top surface of a substrate having recessed regions thereon. The microstructure via the shape and fluid tumbles onto the surface of the substrate, self-aligns, and engages into a recessed region. | 03-25-2010 |
20100207739 | METHODS AND APPARATUSES TO IDENTIFY DEVICES - Embodiments of the present invention include systems with Readers and Tags in which a Reader queries the Tags with a parameter that includes a level of probability of reply according to which the Tags individually and randomly decide whether or not to reply. In one embodiment, the Tags can switch between two states: A and B. The query command also specifies a state (A or B) so that only the Tags in the specified state can reply. After successfully sending the Tag identification data from a Tag to the Reader, the Tag switches to the other state from the specified state. In one embodiment, the operations about the two states are symmetric. In one embodiment, the Tags can remember the parameters used in a query so that a short form of query command can be used to repeat the query with the same query parameters. | 08-19-2010 |
20120154123 | METHODS AND APPARATUSES TO IDENTIFY DEVICES - An apparatus and method to identify devices including a first set of commands to identify devices in a first state and a second set of commands to identify devices in a second state, wherein devices identified in the first state are placed in the second state and devices identified in the second state are placed in the first state. | 06-21-2012 |
John Stephen Szobota, Morristown, NJ US
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20140197071 | FIELD ENHANCED SEPARATION OF HYDROCARBON FRACTIONS - Systems and methods are provided for using field enhanced separations to produce multiple fractions from a petroleum input. A liquid thermal diffusion and/or electric field separation is used to produce the fractions. The fractions can then be used to form multiple outputs that share a first feature while being different with regard to a second feature. For example, a first fraction from the plurality of fractions can have a desired value for a first property such as viscosity index. Two or more additional fractions from the plurality of fractions can then be blended together to make a blended fraction or output. The blended fraction can have a value for the first property that is substantially similar to the value for the first fraction. However, for a second property, the first fraction and the blended fraction can have distinct values. As a result, multiple output fractions can be formed that share a first feature but differ in a second feature. | 07-17-2014 |
20140197075 | FIELD ENHANCED SEPARATION OF HYDROCARBON FRACTIONS - Systems and methods are provided for using field enhanced separations to produce multiple fractions from a petroleum input. A liquid thermal diffusion and/or electric field separation is used to produce the fractions. The fractions can then be used to form multiple outputs that share a first feature while being different with regard to a second feature. For example, a first fraction from the plurality of fractions can have a desired value for a first property such as viscosity index. Two or more additional fractions from the plurality of fractions can then be blended together to make a blended fraction or output. The blended fraction can have a value for the first property that is substantially similar to the value for the first fraction. However, for a second property, the first fraction and the blended fraction can have distinct values. As a result, multiple output fractions can be formed that share a first feature but differ in a second feature. | 07-17-2014 |
John Stephen West, San Diego, CA US
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20090093378 | Method for sequencing a polynucleotide template - The invention relates to methods for pairwise sequencing of a double-stranded polynucleotide template, which methods result in the sequential determination of nucleotide sequences in two distinct and separate regions of the polynucleotide template. | 04-09-2009 |
John Stephen West, Hayward, CA US
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20090247414 | Method and device for nucleic acid sequencing using a planar waveguide - The present invention is concerned with improvements to methods of imaging nucleotides incorporated into polynucleotides and in particular with improved methods of determining the sequence of template nucleic acid molecules using multiple cycle nucleic acid “sequencing-by-synthesis” reactions. | 10-01-2009 |
John Stephen Williams, Bromsgrove GB
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20090119898 | Method of assembling the head of a stirling machine - A method of assembling the head of a Stirling machine. Two sets of fins are fixed within the head casing. At least one regenerator element is passed through a central opening in the fins and is located in place between the two sets of fins. The regenerator elements are made from compacted wire and decompress in situ. | 05-14-2009 |