Patent application number | Description | Published |
20090285750 | AGENT, COMPOSITION AND METHOD - The present application relates to agents, compositions and methods for use in medicine. In particular, the application relates to an agent comprising a binding moiety capable of selectively binding to Ku protein for use in medicine, in particular in the treatment and diagnosis of cancers. | 11-19-2009 |
20100111959 | ENGINEERED ANTI-IL-13 ANTIBODIES, COMPOSITIONS, METHODS AND USES - The present invention relates to engineered antibodies immunospecific for human interleukin-13 (IL-13) protein or fragment thereof, as well as methods of making and using thereof, including therapeutic indications. | 05-06-2010 |
20100261620 | Methods of Humanizing and Affinity-Maturing Antibodies - Methods of humanizing and affinity-maturing antibodies are disclosed. | 10-14-2010 |
20110092372 | Methods of Affinity Maturing Antibodies - The invention relates to methods of affinity maturing antibodies. | 04-21-2011 |
20120045438 | ENGINEERED ANTI-IL-13 ANTIBODIES, COMPOSITIONS, METHODS AND USES - The present invention relates to engineered antibodies immuno specific for human interleukin-13 (IL-13) protein or fragment thereof, as well as methods of making and using thereof, including therapeutic indications. | 02-23-2012 |
20120093833 | Human Oncostatin M Antibodies and Methods of Use - Antibodies and compositions capable of neutralizing oncostatin M biological functions are useful in treating diseases and disorders associated with oncostatin M, such as osteoarthritis and idiopathic pulmonary fibrosis. | 04-19-2012 |
20120225085 | DISPLAY OF DISULFIDE LINKED DIMERIC PROTEINS IN FILAMENTOUS PHAGE - Methods are provided for the display of a complex homodimer protein on the surface of a bacteriophage particle and combinatorial synthetic libraries of such proteins displayed as a fusion polypeptide with filamentous phage pIX coat protein. Heterodimeric or more complex interchain bonded structure, such as disulfide-linked, multimeric proteins, may be displayed using the method of the invention. | 09-06-2012 |
20130243795 | HUMAN ANTI-CD27 ANTIBODIES, METHODS AND USES - Human antibodies immunospecific for human CD27 are capable of blocking CD27 binding to its ligand CD70 and neutralizing bioactivity of CD27 including, but not limited to, CD27 intracellular signaling, T-cell proliferation and activation, B-cell proliferation and differentiation, plasmablast formation and alleviation of antibody responses, stimulation of tumor cells by CD70, and the production of soluble mediators from T and B-cells. The antibodies are useful in diagnosing or treating CD27 activity associated diseases and conditions. | 09-19-2013 |
20140099315 | Human Oncostatin M Antibodies and Methods of Use - Antibodies and compositions capable of neutralizing oncostatin M biological functions are useful in treating diseases and disorders associated with oncostatin M, such as osteoarthritis and idiopathic pulmonary fibrosis. | 04-10-2014 |