Patent application number | Description | Published |
20080293769 | Polymorphs of a C-Met/Hgfr Inhibitor - This invention relates to polymorphs of (R)-3-[1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine that are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to compositions including such salts and polymorphs, and to methods of using such compositions in the treatment of abnormal cell growth in mammals, especially humans. | 11-27-2008 |
20090221608 | PYRAZOLE COMPOUNDS - The present invention is directed to compounds of Formula (I), | 09-03-2009 |
20100105656 | TRIAZOLOPYRAZINE DERIVATIVES - The invention relates to compounds of the formula I | 04-29-2010 |
20100324061 | ENANTIOMERICALLY PURE AMINOHETEROARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS - Enantiomerically pure compound of formula 1 | 12-23-2010 |
20110039856 | POLYMORPHS OF A C-MET/HGFR INHIBITOR - This invention relates to polymorphs of 2-[4-(3-Quinolin-6-ylmethyl-3H-[1,2,3]triazolo[4,5-b]pyrazin-5-yl)-pyrazol-1-yl]-ethanol that are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to compositions including such salts and polymorphs, and to methods of using such compositions in the treatment of abnormal cell growth in mammals, especially humans. | 02-17-2011 |
20120263706 | ENANTIOMERICALLY PURE AMINOHETEROARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS - Enantiomerically pure compound of formula 1 | 10-18-2012 |
20130196952 | HETEROCYCLIC DERIVATIVES FOR THE TREATMENT OF DISEASES - The invention relates to compounds of Formula (1) and to processes for the preparation of intermediates used in the preparation of compositions containing and the uses of such derivatives. The compounds according to the present invention are useful in numerous diseases in which ALK protein is involved or in which inhibition of ALK activity may induce benefit, especially for the treatment of cancer mediated by a mutated EML4-ALK fusion protein. | 08-01-2013 |
20130252961 | MACROCYCLIC DERIVATIVES FOR THE TREATMENT OF DISEASES - The invention relates to compounds of formula (Φ) | 09-26-2013 |
20140135339 | MACROCYCLIC DERIVATIVES FOR THE TREATMENT OF DISEASES - The invention relates to compounds of formula (Φ) | 05-15-2014 |
20140288086 | ENANTIOMERICALLY PURE AMINOHETEROARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS - Enantiomerically pure compound of formula 1 | 09-25-2014 |