Patent application number | Description | Published |
20100033027 | Automatic Pole - An automatic pole includes a mechanical push device and a circuit board device electric-connected with each other. The mechanical push device includes a magnetic inductance device, a contact device, and a housing. The circuit board device comprises a control circuit and an internal cell. The control circuit includes a first optoelectronic coupler and a second optoelectronic coupler electric-connected with each other, and a first transistor which base is connected to the first optoelectronic coupler and a second transistor which base is connected to the second optoelectronic coupler. | 02-11-2010 |
20110281756 | COMPOSITIONS AND METHODS FOR MICRO-RNA EXPRESSION PROFILING OF COLORECTAL CANCER - The present invention relates compositions and methods for microRNA (miRNA) expression profiling of colorectal cancer. In particular, the invention relates to a diagnostic kit of molecular markers for identifying one or more mammalian target cells exhibiting or having a predisposition to develop colorectal cancer, the kit comprising a plurality of nucleic acid molecules, each nucleic acid molecule encoding a miRNA sequence, wherein one or more of the plurality of nucleic acid molecules are differentially expressed in the target cells and in one or more control cells, and wherein the one or more differentially expressed nucleic acid molecules together represent a nucleic acid expression signature that is indicative for the presence of or the predisposition to develop colorectal cancer. The invention further relates to corresponding methods using such nucleic acid expression signatures for identifying one or more mammalian target cells exhibiting or having a predisposition to develop colorectal cancer as well as for preventing or treating such a condition. Finally, the invention is directed to a pharmaceutical composition for the prevention and/or treatment of colorectal cancer. | 11-17-2011 |
20110306595 | SPIROPYRROLIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE - The present invention is directed to spiropyrrolidine compounds of formula (I) which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved. | 12-15-2011 |
20130135858 | LIGHTING BULB - A lighting bulb is provided. The lighting bulb has a housing, a lighting unit and an electrical connector. The housing is configured for accommodating a circuit board and a heat-dissipating sealant is filled in the housing. The lighting unit is coupled to the circuit board for emitting the light and the electrical connector is configured for providing power to the circuit board and the lighting unit. A protruding member disposed on the inner surface of the housing and the circuit board form a mechanical interference against the floating force of the heat-dissipating sealant to the circuit board. | 05-30-2013 |
20130138415 | METHOD AND MODEL FOR MONITORING PRETREATMENT PROCESS OF LOW-K BLOCK LAYER - The present invention provides a method and model for monitoring the pretreatment process of a low-k block layer. The method comprises measuring film parameters of the film formed on the silicon substrate after applying the pretreatment process for different time periods; creating a statistical process control curve according to the film parameters; setting a SPC control limit; determining the pretreatment process normal when the data point of measurement in the SPC curve is within the control limit while determining the pretreatment process abnormal when the data point of measurement in the SPC curve exceeds the control limit. According to the present invention, the failure of the pretreatment process can be prevented to improve the product reliability and stability. | 05-30-2013 |
20140185440 | METHOD AND APPARATUS FOR CONFIGURING CHANNEL RESOURCE, BASE STATION, AND USER EQUIPMENT - A method and an apparatus for configuring a channel resource, a base station, and a user equipment are disclosed. The method includes: determining load information of a cell; according to the load information, that the cell reaches a congested state, configuring channel resource configuration information for a new user equipment accessing the cell, where the configuration information includes: a first DPCH Pilot bit transmit power offset and/or a first number of pilot bits, the first DPCH Pilot bit transmit power offset is smaller than a power offset configured for a user equipment in a non-congested state, and the first number of Pilot bits is smaller than a number of Pilot bits that is configured for a user equipment in a non-congested state, and sending the configuration information to the new user equipment. The method can improve downlink throughput of the cell and reducing a call drop rate. | 07-03-2014 |
20140189995 | METHODS FOR INSTALLING REACTOR COOLANT LOOP PIPING IN A NUCLEAR POWER PLANT - Method for installing reactor coolant loop (RCL) piping of a reactor coolant system (RCS) system in a pressurized water reactor (PWR) nuclear power plant by positioning the reactor vessel, steam generator, or both, into position after attaching one or more coolant pumps, surveying coolant loop piping and a plurality of nozzles on the reactor vessel, the steam generator and coolant pump casing, or a combination thereof, with a precise measurement and 3D modeling technology for positioning data, then performing weld prep machining for the coolant loop piping on the reactor vessel side, and machining for the coolant loop piping on the steam generator side and coolant pump side based on the positioning data, and installing temporary supports for coolant loop piping and finishing the fit-up and welding between the coolant loop piping and the reactor vessel, steam generator, and each coolant pump. | 07-10-2014 |
20140323466 | THIENYL [3,2-D] PYRIMIDIN-4-ONE COMPOUNDS, PREPARATION METHOD, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF - Disclosed are new thienyl[3,2-d]pyrimidin-4-one compounds shown as the general formula (I), preparation method, pharmaceutical compositions and pharmacological use thereof. The compounds are strong DPPIV (dipeptide peptidase IV) inhibitors and can treat type II diabetes through well inhibiting DPPIV indirectly increasing the content of GLP-1 in vivo and inducing a series of physiological actions in vivo. Therefore, the compounds could be developed as new promising drugs for treating diabetes. | 10-30-2014 |
20150038490 | SPIROPYRROLIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE - The present invention is directed to spiropyrrolidine compounds of formula (I) which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved. | 02-05-2015 |