Patent application number | Description | Published |
20080287342 | Compositions Comprising Modified Collagen and Uses Therefor - The invention provides modified collagen and related therapeutic and diagnostic methods. | 11-20-2008 |
20090047740 | CULTURE AID FOR CELLS AND TISSUES - A biological culture medium provides a three-dimensional framework for cell growth. The medium comprises a film and a matrix. | 02-19-2009 |
20090074868 | PHOTOINITIATED TISSUE FILLER - Visible light-activated polymer cosmetic filler preparations useful in a variety of applications are provided. In some embodiments, the photo-activated polymer composition comprises a conventional polymeric material, such as HA, together with a modified, cross-linkable polymer, such as PEG or PEODA, to permit the formation of crosslinks within the polymer matrix in situ on exposure to a visible light source, such as an IPL device. The preparations provide for a more stabilized composition that is contourable during gelation. | 03-19-2009 |
20090324722 | CARTILAGE FILLING DEVICE - Compositions and methods for treating a tissue defect. | 12-31-2009 |
20100137241 | IMIDATED BIOPOLYMER ADHESIVE AND HYDROGEL - Biologically compatible polymers carry an imide and can be used as an adhesive, a hydrogel or both. A second biologically compatible polymer reactive with the imidated polymer can be used therewith to seal openings. | 06-03-2010 |
20100227836 | PARENTERAL ADMINISTRATION OF A GLUCOSAMINE - Materials and methods for local delivery of a glucosamine are provided to facilitate bone and cartilage growth. | 09-09-2010 |
20110002997 | PHOTOINITIATED TISSUE FILLER - Visible light-activated polymer cosmetic filler preparations useful in a variety of applications are provided. In some embodiments, the photo-activated polymer composition comprises a conventional polymeric material, such as HA, together with a modified, cross-linkable polymer, such as PEG or PEODA, to permit the formation of crosslinks within the polymer matrix in situ on exposure to a visible light source, such as an IPL device. The preparations provide for a more stabilized composition that is contourable during gelation. | 01-06-2011 |
20110111034 | METHOD AND MATERIAL FOR ENHANCED TISSUE-BIOMATERIAL INTEGRATION - The present invention relates to the covalent binding of a hydrogel to an extracellular matrix (ECM). The integration of the hydrogel with the tissue is superior to that in previous techniques. Moreover, unlike previous techniques, the present invention does not require a photoinitiator. Potential therapeutic applications include tissue repair and delivery of drugs or cells. | 05-12-2011 |
20120189588 | Compositions and Methods for Implantation of Processed Adipose Tissue and Processed Adipose Tissue Products - The invention provides compositions and methods for the preparation of processed adipose tissue. The invention further provides methods of use of the processed adipose tissue. | 07-26-2012 |
20120231038 | Wound Healing Compositions Comprising Biocompatible Cellulose Hydrogel Membranes and Methods of Use Thereof - The present invention provides a wound healing composition comprising a biocompatible hydrogel membrane wherein the hydrogel membrane has one or more of the following properties: high water content, high transparency, high permeability, high biocompatibility, high tensile strength and an optimal thickness. The invention further provides methods of treating a wound in a subject in need thereof, comprising contacting the wound with a biocompatible cellulose hydrogel membrane of the invention. | 09-13-2012 |
20130032059 | Cellulose-Based Hydrogels and Methods of Making Thereof - The present invention provides cellulose hydrogels having one or more of the following properties: high water content, high transparency, high permeability, high biocompatibility, high tensile strength and an optimal thickness. The present invention further provides a process for preparing a cellulose hydrogel comprising: (i) contacting cellulose with a solvent to activate the cellulose; (ii) optionally removing the solvent from the activated cellulose; (iii) substantially dissolving the activated cellulose to form a solution; (iv) allowing the solution to gel; and optionally (v) drying the gel and rehydrating the gel. The cellulose hydrogel can have many uses, including uses as contact lenses. | 02-07-2013 |
20130109808 | GLUCOSAMINE MATERIALS | 05-02-2013 |
20130116405 | COMPOSITIONS COMPRISING MODIFIED COLLAGEN AND USES THEREFOR - The invention provides modified collagen and related therapeutic and diagnostic methods. | 05-09-2013 |
20140112890 | INTRAOPERATIVE AND BLOOD DERIVED ADHESIVES - The invention features the production of an amine-reactive proteoglycan, specifically chondroitin sulfate or hyaluronic acid. This material can be provided in powder (solid) or liquid form and combined with blood derivatives including serum, platelets, platelet rich plasma, bone marrow, or with other tissue products to form hydrogels. The properties (physical and biological) are different for each of these hydrogels and can be further manipulated by controlling the conditions under which the hydrogels are formed. Such properties include the biodegradability of the hydrogel, the compressibility, the adhesive strength, the presence of pharmaceutical agents or therapeutic cells, and resiliency. | 04-24-2014 |
20140288022 | CROSS-LINKED POLYMER MATRICES, AND METHODS OF MAKING AND USING SAME - Functionalized chondroitin sulfate, cross-linked polymer matrices comprising functionalized chondroitin sulfate, and methods of making and using the same are provided. Such polymer matrices may be used for tissue engineering, reconstructing cartilage, and the like. Kits are also provided for detection of cartilage degrading enzymes. | 09-25-2014 |
20140369975 | BIOMATERIALS COMPRISING HYALURONIC ACID BINDING PEPTIDES AND BIFUNCTIONAL BIOPOLYMER MOLECULES FOR HYALURONIC ACID RETENTION AND TISSUE ENGINEERING APPLICATIONS - The present invention provides novel biomaterial compositions and methods having a technology to improve retention of hyaluronic acid (HA). The biomaterial compositions utilize small HA binding peptides that is tethered to synthetic biocompatible polymers. When tethered to the polymers, the peptide region allows the polymers to bind to HA. The biocompatible polymers are modified to contain a crosslinking group so that the HA can be incorporated into a scaffold and retained in place. The novel biomaterial | 12-18-2014 |
20150044446 | Cellulose Hydrogel Compositions and Contact Lenses for Corneal Applications - The present invention provides cellulose hydrogels having one or more of the following properties: high water content, high transparency, high oxygen permeability, high biocompatibility, high tensile strength and desirable thermal stability. The present invention further provides a process for preparing a cellulose hydrogel comprising (i) a step of activating cellulose, in which the activating step comprises contacting the cellulose with a solvent to activate the cellulose for a time duration from about 2 hours to about 30 hours; (ii) substantially dissolving the activated cellulose to form a solution; and (iii) gelling the solution to form a gel, in which the gelling step comprises allowing the solution to gel in an environment comprising a relative humidity from about 30% to about 80% at 35° C. | 02-12-2015 |