Patent application number | Description | Published |
20110190871 | Crush Recoverable Polymer Scaffolds - A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold has a pattern including an asymmetric closed cell connecting links connecting the closed cells. | 08-04-2011 |
20120073733 | PROCESSES FOR MAKING CRUSH RECOVERABLE POLYMER SCAFFOLDS - Methods for making scaffolds for delivery via a balloon catheter are described. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold structure has patterns that include an asymmetric or symmetric closed cell, and links connecting such closed cells. | 03-29-2012 |
20140058499 | Crush Recoverable Polymer Scaffolds - A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold has a pattern including an asymmetric closed cell connecting links connecting the closed cells. | 02-27-2014 |
20140075735 | Crush Recoverable Polymer Scaffolds - A method of crimping a stent is disclosed. The stent includes a minimum crimped diameter such that in the minimum crimped diameter, a pair of stent rings, between which marker support structures reside, do not make contact with the marker support structures. The crimped profile of the stent of the present invention can be as small as the crimped profile of a same stent but without the maker support structures. | 03-20-2014 |
20140090231 | Crush Recoverable Polymer Scaffolds - A method of manufacturing a stent is disclosed. The stent includes a minimum crimped diameter such that in the minimum crimped diameter, a pair of stent rings, between which marker support structures reside, do not make contact with the marker support structures. The crimped profile of the stent of the present invention can be as small as the crimped profile of a same stent but without the marker support structures. | 04-03-2014 |
Patent application number | Description | Published |
20110177498 | BASE-DETECTING PORE - The invention relates to a mutant α-hemolysin (α-HL) pore which is useful for detecting one or more nucleotides by stochastic sensing. The pore is particularly useful for sequencing DNA or RNA. A molecular adaptor that allows detection of the nucleotide(s) is covalently attached to the pore. The pore is specifically modified to facilitate positioning of the adaptor and may be modified to facilitate covalent attachment. | 07-21-2011 |
20110229877 | ENZYME-PORE CONSTRUCTS - The invention relates to constructs comprising a transmembrane protein pore subunit and a nucleic acid handling enzyme. The pore subunit is covalently attached to the enzyme such that both the subunit and enzyme retain their activity. The constructs can be used to generate transmembrane protein pores having a nucleic acid handling enzyme attached thereto. Such pores are particularly useful for sequencing nucleic acids. The enzyme handles the nucleic acid in such a way that the pore can detect its component nucleotides by stochastic sensing. | 09-22-2011 |
20120064599 | HYBRIDIZATION LINKERS - The invention provides method of covalently coupling two or more moieties, the method comprising: (a) providing a first moiety having covalently attached thereto (i) at least one first linker comprising a first hybridizable region and (ii) at least one first group capable of forming a covalent bond; (b) providing a second moiety having covalently attached thereto (i) at least one second linker comprising a second hybridizable region capable of hybridizing to the first hybridizable region and (ii) at least a second group capable of forming a covalent bond with the first group; (c) contacting the first and second moieties under conditions that allow the first and second hybridizable regions to hybridize and link the moieties; and (d) exposing the linked moieties to conditions that allow the formation of a covalent bond between the first and second groups. | 03-15-2012 |
20120100530 | ENZYME MUTANT - The invention relates to constructs comprising a nucleic acid binding protein and a surface. At least one native accessible cysteine residue is removed from the binding protein. The binding protein is attached to the surface via one or more accessible cysteine residues. The removal of other accessible cysteine residues from the protein allows control attachment to the surface. The constructs can be used to generate transmembrane pores having a nucleic acid binding protein attached thereto. Such pores are particularly useful for sequencing nucleic acids. The enzyme handles the nucleic acid in such a way that the pore can detect each of its component nucleotides by stochastic sensing. | 04-26-2012 |
20140051069 | ENZYME-PORE CONSTRUCTS - The invention relates to constructs comprising a transmembrane protein pore subunit and a nucleic acid handling enzyme. The pore subunit is covalently attached to the enzyme such that both the subunit and enzyme retain their activity. The constructs can be used to generate transmembrane protein pores having a nucleic acid handling enzyme attached thereto. Such pores are particularly useful for sequencing nucleic acids. The enzyme handles the nucleic acid in such a way that the pore can detect its component nucleotides by stochastic sensing. | 02-20-2014 |
20140186823 | MUTANT PORES - The invention relates to mutant forms of Msp. The invention also relates to nucleic acid characterisation using Msp. | 07-03-2014 |
20150031020 | ENZYME-PORE CONSTRUCTS - The invention relates to constructs comprising a transmembrane protein pore subunit and a nucleic acid handling enzyme. The pore subunit is covalently attached to the enzyme such that both the subunit and enzyme retain their activity. The constructs can be used to generate transmembrane protein pores having a nucleic acid handling enzyme attached thereto. Such pores are particularly useful for sequencing nucleic acids. The enzyme handles the nucleic acid in such a way that the pore can detect its component nucleotides by stochastic sensing. | 01-29-2015 |
20150068904 | MUTANT LYSENIN PORES - The invention relates to mutant forms of lysenin. The invention also relates to analyte characterisation using lysenin. | 03-12-2015 |
Patent application number | Description | Published |
20090149200 | System and method for device or system location optimization - Systems, devices and/or methods that facilitate location optimization of mobile devices and/or systems are presented. Location optimization can result in an improved user experience by providing information and/or software tailored to the location of the device and/or system. Location aware devices/systems can include a deterministic or inferential determination of the granular location of the device/system. Location aware devices/systems can also include deterministic or inferential determinations of potential location zone transitions. These determinations and/or inferences can be employed to determine the availability of, and relevance of, device/system updates. Available relevant updates can be downloaded to the device/system at varying levels of granularity and overlap. The downloaded updates can then be installed and made available to the user. | 06-11-2009 |
20090239593 | MOBILE DEVICE EMPLOYING A DEPLOYABLE RFID ANTENNA - Systems, devices and/or methods that facilitate improved form factors for RFID enabled mobile devices with RFID antenna component(s) are presented. These RFID antenna component(s) can be deployable, for example, foldable, slidable, detachable, or combinations thereof, among other means of deployment. By being able to place the RFID antenna component(s) in a packed configuration and/or one or more deployed configurations, the resulting improved form factor can improve usability, reduce maintenance complexity, and facilitate improved performance. Similarly, in a deployed configuration, the resulting form factor can function in a manner equivalent to, or at an improved level over, conventional devices, systems, and/or methods with regard to aspects related to the form factor. | 09-24-2009 |
20090289843 | Method and System for Rendering Changing GPS Position on a Web Page - Described is a method including receiving initial location values of an asset within a monitored region, inserting the initial location values into a web-based document, and rendering an initial position of an icon on the web-based document. Further described is a device including a communication interface receiving initial location values of an asset within a monitored region, a display displaying an image of the monitored region, and a processor inserting the initial location values into a web-based document and rendering an initial position of an icon on the web-based document. The icon represents a location of the asset within the monitored region. | 11-26-2009 |
20090322686 | Control And Navigation For A Device Implementing a Touch Screen - Described is a method which includes the following steps: detecting an input into a touch screen; detecting the release of the input from the touch screen; calculating an elapsed time between the input and the release of the touch screen; and activating a function based on the elapsed time. Described is also a device. The device includes a memory storing a plurality of functions and a corresponding time interval for each function; a tactile input detecting an activation and a release; a timer determining an elapsed amount of time between the activation and the release of the tactile input; and a processor activating one of the plurality of functions based on the elapsed time and the corresponding time interval. | 12-31-2009 |