Jatkoe
Tim Jatkoe, Gladstone, NJ US
Patent application number | Description | Published |
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20110009288 | METHODS AND REAGENTS FOR THE EARLY DETECTION OF MELANOMA - An assay for identifying early stage malignant melanocyte in biopsy tissues is provided by determining whether differential expression of a particular gene indicative of melanoma exceed a cut-off value. | 01-13-2011 |
20140303028 | GENOMIC DIAGNOSTICS USING CIRCULATING ENDOTHELIAL CELLS - Circulating Endothelial Cells are isolated from patient blood and gene expression of the cells is analyzed to assess a medical condition or the tissue of origin of the cell. Kits for conducting the method are also provided. | 10-09-2014 |
Tim Jatkoe, La Jolla, CA US
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20100009371 | SELECTION OF MARKERS - Methods of selecting a portfolio of markers for use in a diagnostic applications include defining diagnostic parameters, establishing a relationship among the parameters so that they are optimized, and selecting an optimal group of markers for the diagnostic application. The diagnostic parameters can include a measure of the relative degree of expression of a gene, a measure of the variation in the measurement of the degree of expression of the gene, and the relationship between the diagnostic and discriminating parameters can be a mean variance relationship. | 01-14-2010 |
Tim Jatkoe, Bedminster, NJ US
Timothy Jatkoe, San Diego, CA US
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20100021886 | Methods and Materials for Identifying the Origin of a Carcinoma of Unknown Primary Origin - The present invention provides a method of identifying origin of a metastasis of unknown origin by obtaining a sample containing metastatic cells; measuring Biomarkers associated with at least two different carcinomas; combining the data from the Biomarkers into a linear discrimination analysis where the linear discrimination analysis normalizes the Biomarkers against a reference; and imposes a cut-off which optimizes sensitivity and specificity of each Biomarker, weights the prevalence of the carcinomas and selects a tissue of origin determining origin based on highest probability determined by the linear discrimination analysis or determining that the carcinoma is not derived from a particular set of carcinomas; and optionally measuring Biomarkers specific for one or more additional different carcinoma, and repeating the steps for additional Biomarkers. | 01-28-2010 |
Timothy Jatkoe, Gladstone, NJ US
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20130059755 | Gene Based Prediction of PSA Recurrence for Clinically Localized Prostate Cancer Patients - Disclosed are methods, devices and kits for determining the likelihood of recurrence of prostate cancer using the expression levels of preferably three-gene classifier. The methods, devices and kits can be used independent of many nomograms currently in use or to improve the overall performance of such nomograms. | 03-07-2013 |
Timothy Jatkoe, Bedminster, NJ US
Patent application number | Description | Published |
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20150361496 | PREDICTIVE ANALYSIS FOR MYOCARDIAL INFARCTION - Compositions, systems and methods for the diagnosing the risk of acute myocardial infarction are provided. The methods described herein relate to the use of biomarkers, such as gene expression profiles, and analytical tools for providing information to a health care provider or the patient, that is relevant to the cardiovascular health of the patient. | 12-17-2015 |