Patent application number | Description | Published |
20100157309 | SPECKLE REDUCTION IN OPTICAL COHERENCE TOMOGRAPHY BY PATH LENGTH ENCODED ANGULAR COMPOUNDING - Speckle, a factor reducing image quality in optical coherence tomography (“OCT”), can limit the ability to identify cellular structures that are important for the diagnosis of a variety of diseases. Exemplary embodiments of the present invention can facilitate an implementation of an angular compounding, angular compounding by path length encoding (“ACPE”) for reducing speckle in OCT images. By averaging images obtained at different incident angles, with each image encoded by path length, ACPE maintains high-speed image acquisition and implements minimal modifications to OCT probe optics. ACPE images obtained from tissue phantoms and human skin in vivo demonstrate a qualitative improvement over traditional OCT and an increased signal-to-noise ratio (“SNR”). Accordingly, exemplary embodiments of an apparatus probe catheter and method can be provided for irradiating a structure. In particular, an interferometer may forward forwarding an electromagnetic radiation. In addition, a sample arm may receive the electromagnetic radiation, and can include an arrangement which facilitates a production of at least two radiations from the electromagnetic radiation so as to irradiate the structure. Such exemplary arrangement can be configured to delay a first radiation of the at least two radiations with respect to a second radiation of the at least two radiations. | 06-24-2010 |
20120281237 | SPECKLE REDUCTION IN OPTICAL COHERENCE TOMOGRAPHY BY PATH LENGTH ENCODED ANGULAR COMPOUNDING - Accordingly, exemplary embodiments of an apparatus probe catheter and method can be provided for irradiating a structure. In particular, an interferometer may forward forwarding an electromagnetic radiation. In addition, a sample arm may receive the electromagnetic radiation, and can include an arrangement which facilitates a production of at least two radiations from the electromagnetic radiation so as to irradiate the structure. Such exemplary arrangement can be configured to delay a first radiation of the at least two radiations with respect to a second radiation of the at least two radiations. | 11-08-2012 |
20120328241 | Apparatus for Obtaining Information For A Structure Using Spectrally-Encoded Endoscopy Techniques and Methods for Producing One or More Optical Arrangements - Exemplary apparatus for obtaining information for a structure can be provided. For example, the exemplary apparatus can include at least one first optical fiber arrangement which is configured to transceive at least one first electro-magnetic radiation, and can include at least one fiber. The exemplary apparatus can also include at least one second focusing arrangement in optical communication with the optical fiber arrangement. The second arrangement can include a ball lens, and be configured to focus and provide there through the first electro-magnetic radiation to generate focused electro-magnetic radiation. Further, the exemplary apparatus can include at least at least one dispersive third arrangement which can receive a particular radiation (e.g., the first and/or focused electro-magnetic radiation(s), and forward a dispersed radiation thereof to at least one section of the structure. An end of the fiber(s) can be directly connected to the second focusing arrangement and/or the third arrangement(s). | 12-27-2012 |
20130314716 | SPECKLE REDUCTION IN OPTICAL COHERENCE TOMOGRAPHY BY PATH LENGTH ENCODED ANGULAR COMPOUNDING - Accordingly, exemplary embodiments of an apparatus obtaining information associated with a structure can be provided. For example, with a first arrangement, it is possible to separate at least one first electro-magnetic radiation into a first radiation and a second radiation forwarded to the structure, with the first and second radiations having different path lengths. Using a second arrangement, it is possible to receive third and fourth radiations from the structure associated with the first and second radiations and a fifth radiation received from a reference. Further, with a third arrangement, it is possible to generate data corresponding to an amount of a ranging depth within the structure associated with the second arrangement. For example, a difference between the path lengths of the first and second radiations is equal or greater than the ranging depth. | 11-28-2013 |
20150045622 | SPECTRALLY-ENCODED ENDOSCOPY TECHNIQUES, APPARATUS AND METHODS - Exemplary apparatus for obtaining information for a structure can be provided. For example, the exemplary apparatus can include at least one first optical fiber arrangement which is configured to transceive at least one first electro-magnetic radiation, and can include at least one fiber. The exemplary apparatus can also include at least one second focusing arrangement in optical communication with the optical fiber arrangement. The second arrangement can be configured to focus and provide there through the first electro-magnetic radiation to generate the focused electro-magnetic radiation. Further, the exemplary apparatus can include at least at least one dispersive third arrangement which can receive a particular radiation (e.g., the first electro-magnetic radiation(s) and/or the focused electro-magnetic radiation), and forward a dispersed radiation thereof to at least one section of the structure. | 02-12-2015 |
Patent application number | Description | Published |
20100073634 | Hybrid Spectral Domain Optical Coherence Tomography Line Scanning Laser Ophthalmoscope - An apparatus for imaging an eye includes a housing and a system of optical components disposed in the housing. The apparatus is capable of operating in a line scanning laser opthalmoscope (LSLO) mode and an optical coherence tomography (OCT) mode. The system of optical components can include a first source to provide a first beam of light for the OCT mode and a second source to provide a second beam of light for the LSLO mode. In the OCT mode, a first optic is used that (i) scans, using a first surface of the first optic, the first beam of light along a retina of an eye in a first dimension, and (ii) descans, using the first surface, a first light returning from the eye in the first dimension to a detection system in the OCT mode. In the LSLO mode, the first optic is used where the second beam of light passes through a second surface of the first optic. | 03-25-2010 |
20100195048 | Adaptive Optics Line Scanning Ophthalmoscope - A first optical module scans a portion of an eye with a line of light, descans reflected light from the scanned portion of the eye and confocally provides output light in a line focus configuration. A detection device detects the output light and images the portion of the eye. A second optical module detects an optical distortion and corrects the optical distortion in the line of light scanned on the portion of the eye. | 08-05-2010 |
20100253908 | Stabilized Retinal Imaging With Adaptive Optics - A system provides an optical image of an object. A first module tracks a reference feature of the object. A second module includes a source for an imaging beam, a scanning device to move the imaging beam along a portion of the object and a detection device receives a signal associated with an image of the portion of the object. The first module controls the position of the imaging beam relative to the reference feature to correct for the motion of the object. A third module detects a distortion of the object and compensates for the distortion. | 10-07-2010 |
20110085136 | Hybrid Spectral Domain Optical Coherence Tomography Line Scanning Laser Ophthalmoscope - An apparatus for imaging an eye includes a housing and a system of optical components disposed in the housing. The apparatus is capable of operating in a line scanning laser ophthalmoscope (LSLO) mode and an optical coherence tomography (OCT) mode. The system of optical components can include a first source to provide a first beam of light for the OCT mode and a second source to provide a second beam of light for the LSLO mode. In the OCT mode, a first optic is used that (i) scans, using a first surface of the first optic, the first beam of light along a retina of an eye in a first dimension, and (ii) descans, using the first surface, a first light returning from the eye in the first dimension to a detection system in the OCT mode. In the LSLO mode, the first optic is used where the second beam of light passes through a second surface of the first optic. | 04-14-2011 |
20110152845 | STABILIZED RETINAL IMAGING WITH ADAPTIVE OPTICS - A system provides an optical image of an object. A first module tracks a reference feature of the object. A second module includes a source for an imaging beam, a scanning device to move the imaging beam along a portion of the object and a detection device receives a signal associated with an image of the portion of the object. The first module controls the position of the imaging beam relative to the reference feature to correct for the motion of the object. A third module detects a distortion of the object and compensates for the distortion. | 06-23-2011 |
20110234978 | Multi-functional Adaptive Optics Retinal Imaging - An optical apparatus includes a system of optical components capable of operating in a scanning laser ophthalmoscope (SLO) mode and an optical coherence tomography (OCT) mode. The system of optical components includes a first optical module for the SLO mode, a second optical module for the OCT mode, and a first scanning device. The first optical module for the SLO mode includes a first source adapted to provide a first imaging beam for the SLO mode and a first detection device configured to receive a first signal associated with a first image of a retina of an eye. The second optical module for the OCT mode includes a second source adapted to provide a second imaging beam for the OCT mode and a second detection device configured to receive a second signal associated with a second image of the retina. The first scanning device is configured to move the first imaging beam along the retina in the slow axis of the SLO mode to acquire the first image and (ii) to move the second imaging beam along the retina in the fast axis of the OCT mode to acquire the second image. | 09-29-2011 |
20120062843 | Hybrid Spectral Domain Optical Coherence Tomography Line Scanning Laser Ophthalmoscope - A method of imaging a retina of an eye includes combining an optical path of an optical coherence tomography (OCT) imager and an optical path of a line scanning laser ophthalmoscope (LSLO) imager using a system of optics. The method also includes using a single detector to switch between an OCT mode and a LSLO mode and acquiring images of the retina while switching between the OCT mode and the LSLO mode. | 03-15-2012 |
20120101390 | Multi-Modal Imaging for Diagnosis of Early Stage Epithelial Cancers - Epithelial cancer screening can include a staining tissue with a cancer targeting agent, identifying a potentially cancerous lesion using fluorescence imaging, and imaging the potentially cancerous lesion for a cancer diagnosis using optical coherence tomography. | 04-26-2012 |
20130229620 | Enhanced Sensitivity Line Field Detection - A retinal imaging device includes an optical system configured to (i) scan a portion of the retina of the eye with a line of light, (ii) descan reflected light from the scanned portion of the retina, and (iii) provide output light in a line focus configuration. The device includes a detection device including a linear array of asymmetric pixels having at least a 2:1 ratio of length to width, a detection device with multiple adjacent linear arrays, and/or a detection device using a time delay and integration (TDI) architecture. | 09-05-2013 |
20140031677 | Apparatus and Method for Aiding Needle Biopsies - A handheld optical coherence tomography imaging and tissue sampling system and method of imaging and sampling a tissue is disclosed. The method includes inserting a catheter probe into a biopsy needle. The biopsy needle can be attached to a hand-held scanning and sampling device. The biopsy needle is maneuvered to an investigation site. A three-dimensional image of the tissue at the investigation site is captured with the catheter probe. | 01-30-2014 |
20140213897 | Combined Reflectance Confocal Microscopy-Optical Coherence Tomography System for Imaging of Biological Tissue - A dual-modality apparatus for imaging of biological tissue includes a reflectance confocal microscopy (RCM) imaging apparatus and an optical coherence tomography (OCT) imaging apparatus. A first optical component reflects a first beam of light provided by a RCM imaging apparatus towards a sample and passes a second beam of light provided by an OCT imaging apparatus towards the sample, such that the first and second beam of lights share at least a portion of an imaging path. | 07-31-2014 |
20140247425 | Multi-Functional Adaptive Optics Retinal Imaging - An optical apparatus includes a system of optical components capable of operating in a scanning laser ophthalmoscope (SLO) mode and an optical coherence tomography (OCT) mode. The system of optical components includes a first optical module for the SLO mode, a second optical module for the OCT mode, and a first scanning device. The first optical module for the SLO mode includes a first source adapted to provide a first imaging beam for the SLO mode and a first detection device configured to receive a first signal associated with a first image of a retina of an eye. The second optical module for the OCT mode includes a second source adapted to provide a second imaging beam for the OCT mode and a second detection device configured to receive a second signal associated with a second image of the retina. The first scanning device is configured to move the first imaging beam along the retina in the slow axis of the SLO mode to acquire the first image and (ii) to move the second imaging beam along the retina in the fast axis of the OCT mode to acquire the second image. | 09-04-2014 |