Hüseyin
Hüseyin Aygün, Frankfurt Am Main DE
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20100144010 | Enzymatic Asymmetric Decarboxylation of Disubstituted Malonic Acids - A process for the stereoselective decarboxylation of malonic acid derivatives with mutated decarboxylases is disclosed. | 06-10-2010 |
Hüseyin Firat, Paris FR
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20110250650 | LENTIVIRAL VECTORS FOR THE PREPARATION OF IMMUNOTHERAPEUTICAL COMPOSITIONS - The invention relates to an immunogenic composition comprising a recombinant vector characterized in that it comprises a polynucleotide comprising the cis-acting central initiation region (cPPT) and the cis-acting termination region (CTS), these regions being of retroviral or retroviral-like origin, said vector comprising in addition a defined nucleotide sequence (transgene or sequence of interest) and regulatory signals of retrotranscription, expression and encapsidation of retroviral or retroviral-like origin, wherein the composition is capable of inducing or of stimulating a cell-mediated response for instance a CTL (Cytotoxic T Lymphocytes) response or a CD4 response, against one or several epitopes encoded by the transgene sequence present in the vector. | 10-13-2011 |
20120095083 | USE OF TRIPLEX STRUCTURE DNA IN TRANSFERRING NUCLEOTIDE SEQUENCES - A method to induce an immune response in a host in need thereof, comprises administering to the host, recombinant lentiviral vector particles comprising: | 04-19-2012 |
20120252113 | USE OF TRIPLEX STRUCTURE DNA IN TRANSFERRING NUCLEOTIDE SEQUENCES - The invention concerns a recombinant vector characterized in that it comprises a polynucleotide comprising a central initiation cis-active region (cPPT) and a termination cis-active region (CTS), the regions being of retroviral or retroviral-like origin, and the vector further comprising a predetermined nucleotide sequence (transgene or nucleotide sequence of interest) and retrotranscription regulating, expressing, and packaging signals of retroviral or retroviral-like origin. | 10-04-2012 |
20120252114 | USE OF TRIPLEX STRUCTURE DNA IN TRANSFERRING NUCLEOTIDE SEQUENCES - The invention concerns a recombinant vector characterized in that it comprises a polynucleotide comprising a central initiation cis-active region (cPPT) and a termination cis-active region (CTS), the regions being of retroviral or retroviral-like origin, and the vector further comprising a predetermined nucleotide sequence (transgene or nucleotide sequence of interest) and retrotranscription regulating, expressing, and packaging signals of retroviral or retroviral-like origin. | 10-04-2012 |
Hüseyin Hacihabiboglu, Guildford GB
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20120093337 | Microphone Array - Embodiments of the invention improve upon the prior art array by having more carefully defined directivity functions designed to meet two criteria, being firstly to minimise cross-talk between non-adjacent microphones in the array, and secondly to design the array response such that it approximates stereophonic panning curves that have been shown to provided for good auditory localisation. One embodiment therefore provides a microphone array, comprising N microphones, wherein N is greater than or equal to 3. The microphones are substantially equiangularly arranged over a circular arc subtending an angle ε, wherein ε is less than or equal to 2π, with the directional axes of the N microphones facing substantially radially outwards. Each of the N microphones have a substantially common directivity function Γ(θ) defining the directional response of the microphone, wherein θ=0 is the directional axis, and the directivity function Γ(θ) is arranged such that a sound source in acoustical free field is effectively captured by no more than two consecutive microphones in the array. By arranging the directivity function in this manner crosstalk between non-adjacent microphones can be minimised, which has been shown to improve auditory localisation performance. | 04-19-2012 |
Hüseyin Oguz, Istanbul TR
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20110211809 | VIDEO-GENRE CLASSIFICATION - An exemplary embodiment of the invention relates to a method for classifying a video sequence (VS), characterized by the steps of analyzing the video sequence using a plurality of genre-specific detector modules (M | 09-01-2011 |
Hüseyin Sirma, Elmshorn DE
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20100135966 | AGENTS FOR TREATING FLAVIVIRIDAE INFECTIONS - The invention relates to agents for the treatment, therapy and inhibition of Flaviviridae virus infections, which agents comprise proteasome inhibitors as the active component. The agents which are used for inhibiting the release, maturation and replication of Flaviviridae comprise, as the active component in pharmaceutical preparations, substance classes which share the common property of inhibiting the 26S proteasome in cells. These substance classes include, in particular, proteasome inhibitors which affect the activities of the ubiquitin/proteasome pathway, in particular the enzymic activities of the 26S and the 20S proteasome complex. The application of the invention lies in the antiviral therapy of Flaviviridae infections, especially in preventing the establishment and maintenance of a chronic hepatitis C virus infection and a hepatopathogenesis which is associated therewith. | 06-03-2010 |
Hüseyin Sirma, Elmshorn DE
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20090105186 | Beta-L-N4-Hydroxycytosine Deoxynucleosides and their use as Pharmaceutical Agents in the Prophylaxis or Therapy of Viral Diseases - The invention relates to β-L-N4-hydroxycytosine nucleo-sides, pharmaceutical agents comprising same, and to the use of said β-L-N4-hydroxycytosine nucleosides and pharmaceutical agents in the prophylaxis or therapy of an infection caused by hepatitis B virus (HBV) or human immunodeficiency virus (HIV). The invention also relates to a method for the preparation of said β-L-nucleoside analogs. | 04-23-2009 |
20100135966 | AGENTS FOR TREATING FLAVIVIRIDAE INFECTIONS - The invention relates to agents for the treatment, therapy and inhibition of Flaviviridae virus infections, which agents comprise proteasome inhibitors as the active component. The agents which are used for inhibiting the release, maturation and replication of Flaviviridae comprise, as the active component in pharmaceutical preparations, substance classes which share the common property of inhibiting the 26S proteasome in cells. These substance classes include, in particular, proteasome inhibitors which affect the activities of the ubiquitin/proteasome pathway, in particular the enzymic activities of the 26S and the 20S proteasome complex. The application of the invention lies in the antiviral therapy of Flaviviridae infections, especially in preventing the establishment and maintenance of a chronic hepatitis C virus infection and a hepatopathogenesis which is associated therewith. | 06-03-2010 |
Hüseyin Tüblüker, Heiligenhaus DE
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20100148559 | HEAD RESTRAINT FOR A SEAT, IN PARTICULAR A VEHICLE SEAT - A headrest ( | 06-17-2010 |
Hüseyin Tüblüker, Heiligenhaus DE
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20100148559 | HEAD RESTRAINT FOR A SEAT, IN PARTICULAR A VEHICLE SEAT - A headrest ( | 06-17-2010 |