Patent application number | Description | Published |
20110110922 | Wound Healing Peptides and Methods of Use Thereof - Methods and compositions for the treatment of wounds in a mammalian subject are provided. Particularly, novel polypeptides and encoding nucleic acids that stimulate keratinocyte and endothelial cell motility and/or proliferation are provided. | 05-12-2011 |
20120178901 | NUCLEIC ACIDS ENCODING PEPTIDES FOR TREATING WOUNDS, ANTI-ANGIOGENIC COMPOUNDS AND USES THEREOF - The present disclosure relates to protein and peptide chemistry. More particularly, it relates to compounds, compositions and uses thereof for promoting and inhibiting angiogenesis. The peptides of the present disclosure include peptides comprising SEQ ID NOs: 1-4 which promote angiogenesis and cell proliferation. Further, the anti-angiogenic compounds of the present disclosure include antisense oligonucleotides that hybridize or are complementary to the polynucleotides of SEQ ID NOs: 5-16, and the like. | 07-12-2012 |
20130108614 | WOUND HEALING PEPTIDES AND METHODS OF USE THEREOF | 05-02-2013 |
20130316956 | NUCLEIC ACIDS ENCODING PEPTIDES FOR TREATING WOUNDS, ANTI-ANGIOGENIC COMPOUNDS AND USES THEREOF - The present disclosure relates to protein and peptide chemistry. More particularly, it relates to compounds, compositions and uses thereof for promoting and inhibiting angiogenesis. The peptides of the present disclosure include peptides comprising SEQ ID NOs: 1-4 which promote angiogenesis and cell proliferation. Further, the anti-angiogenic compounds of the present disclosure include antisense oligonucleotides that hybridize or are complementary to the polynucleotides of SEQ ID NOs: 5-16, and the like. | 11-28-2013 |
20140371154 | NUCLEIC ACIDS ENCODING PEPTIDES FOR TREATING WOUNDS, ANTI-ANGIOGENIC COMPOUNDS AND USES THEREOF - The present disclosure relates to protein and peptide chemistry. More particularly, it relates to compounds, compositions and uses thereof for promoting and inhibiting angiogenesis. The peptides of the present disclosure include peptides comprising SEQ ID NOs: 1-4 which promote angiogenesis and cell proliferation. Further, the anti-angiogenic compounds of the present disclosure include antisense oligonucleotides that hybridize or are complementary to the polynucleotides of SEQ ID NOs: 5-16, and the like. | 12-18-2014 |
20140371155 | NUCLEIC ACIDS ENCODING PEPTIDES FOR TREATING WOUNDS, ANTI-ANGIOGENIC COMPOUNDS AND USES THEREOF - The present disclosure relates to protein and peptide chemistry. More particularly, it relates to compounds, compositions and uses thereof for promoting and inhibiting angiogenesis. The peptides of the present disclosure include peptides comprising SEQ ID NOs: 1-4 which promote angiogenesis and cell proliferation. Further, the anti-angiogenic compounds of the present disclosure include antisense oligonucleotides that hybridize or are complementary to the polynucleotides of SEQ ID NOs: 5-16, and the like. | 12-18-2014 |
20150353612 | NUCLEIC ACIDS ENCODING PEPTIDES FOR TREATING WOUNDS, ANTI-ANGIOGENIC COMPOUNDS AND USES THEREOF - The present disclosure relates to protein and peptide chemistry. More particularly, it relates to compounds, compositions and uses thereof for promoting and inhibiting angiogenesis. The peptides of the present disclosure include peptides comprising SEQ ID NOs: 1-4 which promote angiogenesis and cell proliferation. Further, the anti-angiogenic compounds of the present disclosure include antisense oligonucleotides that hybridize or are complementary to the polynucleotides of SEQ ID NOs: 5-16, and the like. | 12-10-2015 |
Patent application number | Description | Published |
20150126438 | Novel ChREBP Isoforms and Methods Using the Same - The invention provides diagnostic and prognostic methods and methods of evaluating treatment protocols for disorders such as obesity, diabetes, metabolic syndrome, cancer and vascular disease by detecting the levels of a novel isoform of ChREBP, termed ChREBP β. The invention also provides nucleic acids, proteins, reporter constructs based on ChREBP β and methods of identifying one or more agents that modulate the expression of a ChREBP β target gene. | 05-07-2015 |
20150133551 | Lipids That Increase Insulin Sensitivity And Methods Of Using The Same - The invention provides, inter alia, fatty acyl hydroxy fatty acid (FAHFA; a novel class of estolide-related molecules) and diagnostic and treatment methods for a variety of disorders—including diabetes-related disorders, Metabolic Syndrome, polycyctic ovarian syndrome, cancer, and inflammatory disorders using them; as well as methods of screening for additional compounds that are useful in treating these disorders and/or that modulate FAHFA levels, FAHFA-mediated signaling, and FAHFA-mediated biological effects. | 05-14-2015 |
Patent application number | Description | Published |
20090289706 | Cube coordinate subspaces for nonlinear digital predistortion - A method or corresponding apparatus relates to a mathematical approach to efficiently search for and localize regions in a multi-dimensional signal space to enable inversion of power amplifier nonlinearities with a significant reduction in computational complexity and an efficient hardware implementation. To linearize a wideband power amplifier, an example embodiment of the present invention may represent a response of the wideband power amplifier using coefficients in a cube coefficient subspace, and search over the full multi-dimensional subspace according to an optimization criterion in order to identify a vector of cube coefficient subspace coefficients. The vector of coefficient subspace coefficients may be used to linearize the wide-band power amplifier. | 11-26-2009 |
20120147943 | Method and Apparatus for Complex In-Phase/Quadrature Polyphase Nonlinear Equalization - Complex polyphase nonlinear equalizer (cpNLEQs) mitigate nonlinear distortions generated by complex in-phase/quadrature (I/Q) time-interleaved analog-to-digital converters (TIADCs). Example cpNLEQs upsample the digital waveform emitted by the TIADC, e.g., by a factor of two, then separate the upsampled digital waveform into upsampled in-phase and quadrature components. Processors in the cpNLEQs create real and imaginary nonlinear compensation terms from the upsampled in-phase and quadrature components. The nonlinear compensation terms are downsampled, and the downsampled imaginary nonlinear compensation term is phase-shifted, then combined with the downsampled real component to produce an estimated residual distortion. Subtracting the estimated residual distortion from the digital waveform emitted by the TIADC yields an equalized digital waveform suitable for further processing. | 06-14-2012 |
20120176190 | Polyphase Nonlinear Digital Predistortion - Polyphase nonlinear digital predistorters (pNDPs) mitigate nonlinear distortions generated by time-interleaved digital-to-analog converters (TIDACs). Processors in an example pNDP compute nonlinear and linear compensation terms representative of channel mismatches and other imperfections in the TIDAC based on the digital input to the TIDAC. The pNDP subtracts these compensation terms from a delayed copy of the digital input to yield a predistorted digital input. The TIDAC converts on the predistorted digital input into a fullband analog output that is substantially free of nonlinear distortion. | 07-12-2012 |
Patent application number | Description | Published |
20130299567 | Vessel and Method for Making the Same - A vessel composed of a sheet of flexible material, cut, rolled, and affixed to form a frusto-conically shaped base region. The sheet when rolled including an upper region having two opposing flaps, each flap delineated from a remaining portion of the sheet by a path along which the sheet is scored, so that the flaps, when folded along their respective paths, define a single elevated drinking portion having a spout formed between an extension of the base region and at least one of the two flaps. | 11-14-2013 |
20150021382 | Vessel and Method for Making the Same - A vessel composed of a sheet of flexible material, cut, rolled, and affixed to form a frusto-conically shaped base region. The sheet when rolled including an upper region having two opposing flaps, each flap delineated from a remaining portion of the sheet by a path along which the sheet is scored, so that the flaps, when folded along their respective paths, define a single elevated drinking portion having a spout formed between an extension of the base region and at least one of the two flaps. | 01-22-2015 |
20150272361 | Vessel With Folded Dam - A vessel has an inner flap and an outer flap that fold across a base of the vessel to form a cover. The inner flap includes a dam tab along the outer edge of the inner flap. When the inner flap is folded down, the free edge of this tab contacts the wall of the vessel and bends upward forming a “folded edge” dam. This folded edge dam can either be one segment or be made of two or more segments divided by one or more V-shaped cuts to allow each segment to fold down and fit together seamlessly. A restrictive channel is formed by the outer and inner flaps together with the “folded edge” dam, which is present in-between the outer and inner flaps. | 10-01-2015 |
Patent application number | Description | Published |
20090030404 | CONTAINMENT DEVICE WITH MULTI-LAYER RESERVOIR CAP STRUCTURE - Devices and methods are provided for the controlled release or exposure of reservoir contents. The device includes a substrate, a plurality of reservoirs in the substrate, reservoir contents disposed in the reservoirs, discrete reservoir caps covering each reservoir to seal the reservoir contents in the reservoirs, and control circuitry for selectively disintegrating the reservoir caps to release or expose the reservoir contents in vivo. At least one of the reservoir caps comprises a first electrically conductive layer coated with one or more protective layers. In one embodiment, the control circuitry comprises an electrical input lead and an electrical output lead connected to and directly contacting each of said reservoir caps and a source of electric power for applying an electrical current through each reservoir cap in an amount effective to rupture each of the reservoir caps. | 01-29-2009 |
20100023071 | SYSTEMS AND DEVICES FOR NEURAL STIMULATION AND CONTROLLED DRUG DELIVERY - Medical devices and methods are provided for electrical stimulation of neural tissue and controlled drug delivery to a patient. The device includes an implantable drug delivery module which comprises a plurality of reservoirs, a release system comprising at least one drug contained in each of the reservoirs, and control means for selectively releasing a pharmaceutically effective amount of drug from each reservoir; a neural electrical stimulator which comprises a signal generator connected to at least one stimulation electrode for operable engagement with a neural tissue of the patient; and at least one microcontroller for controlling operational interaction of the drug delivery module and the neural electrical stimulator. The microcontroller may control the signal generator and the control means of the drug delivery module. The device may further include a sensor operable to deliver a signal to the microcontroller, for example to indicate when to deliver electrical stimulation, drug, or both. | 01-28-2010 |
20110172587 | METHOD AND SYSTEM FOR DRUG DELIVERY TO THE EYE - Methods and systems are provided for delivering drug to the eye. The method and system may include implanting into the eye a device which comprises two or more discrete reservoirs, each reservoir containing a drug; and directing focused light to the implanted device to open a first one of the reservoirs and thereby permit the drug to diffuse from the first reservoir to the patient's eye. | 07-14-2011 |
20140107417 | Cannula with Integrated Camera and Illumination - A cannula assembly includes a tubular element forming a lumen, a deployable element of a subassembly, and an electronic component mounted to the deployable element. The tubular element has a proximal end and a distal end adapted to be inserted into a body cavity. The deployable element is coupled through the subassembly to the tubular element, and is adapted to transition between a closed position and an open position. The electronic component has at least one imaging device and at least one illumination source. The subassembly, including the deployable element and the electronic component, are releasable from the tubular element. | 04-17-2014 |