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Guoqiang Wang, Belmont US

Guoqiang Wang, Belmont, MA US

Patent application numberDescriptionPublished
200802622086-11 Bridged Oxime Erythromycin Derivatives - The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof:10-23-2008
200901185066,11-BRIDGED BIARYL MACROLIDES - The present invention discloses compounds of formula I, II or, or pharmaceutically acceptable salts, esters, or prodrugs thereof:05-07-2009
20090209547C-8 HALOGENATED MACROLIDES - The present invention discloses compounds of formula (I) or pharmaceutically acceptable salts, esters, or prodrugs thereof:08-20-2009
200902643806,11-BRIDGED BIARYL MACROLIDES - The present invention discloses compounds of formula I, II or X, or pharmaceutically acceptable salts, esters, or prodrugs thereof:10-22-2009
201000416186-11 Bridged Oxime Erythromycin Derivatives - The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof:02-18-2010
20100196316CYCLOSPORIN ANALOGUES FOR PREVENTING OR TREATING HEPATITIS C INFECTION - The present invention relates to cyclosporin analogues having antiviral activity against HCV and useful in the treatment of HCV infections. More particularly, the invention relates to novel cyclosporin analogue compounds, compositions containing such compounds and methods for using the same, as well as processes for making such compounds.08-05-2010
20110008284NOVEL CLYCLOSPORIN ANALOGUES - The present invention provides novel cyclosporin analogue compounds, pharmaceutical compositions comprising these compounds and methods of using these compounds for the treatment of disorders and diseases, including immune disorders, inflammatory disorders and viral infections.01-13-2011
20110008285NOVEL CYCLOSPORIN ANALOGUES - The present invention provides novel cyclosporin analogue compounds, pharmaceutical compositions comprising these compounds and methods of using these compounds for the treatment of disorders and diseases, including immune disorders, inflammatory disorders and viral infections.01-13-2011
20110008286NOVEL PROLINE SUBSTITUTED CYCLOSPORIN ANALOGUES - The present invention provides novel proline substituted cyclosporinanalogue compounds, pharmaceutical compositions comprising these compounds and methods of using these compounds for the treatment of disorders and diseases, including immune disorders, inflammatory disorders and viral infections.01-13-2011
20110033420MACROCYCLIC COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS - The present invention discloses compounds of formula I or pharmaceutically acceptable salts, esters, or prodrugs thereof:02-10-2011
20110123496BISMACROCYCLIC COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS - The present invention discloses compounds of formula Ia or Ib or pharmaceutically acceptable salts, esters, or prodrugs thereof:05-26-2011
20110206637ANTIVIRAL AGENTS - The present invention provides antiviral compounds of formula (I),08-25-2011
20110218175ANTIVIRAL AGENTS - The present invention relates to antiviral compounds of formula (I),09-08-2011
201200353526-11 Bicyclic Ketolide Derivatives - The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof:02-09-2012
20120070416Macrocyclic Proline Derived HCV Serine Protease Inhibitors - The present invention discloses compounds of Formula I or pharmaceutically acceptable salts, esters, or prodrugs thereof:03-22-2012
20120101031MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS - The present invention relates to novel macrocyclic compounds and methods of treating a hepatitis C infection in a subject in need of such therapy with said macrocyclic compounds. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient.04-26-2012
201202374802'ALLENE-SUBSTITUTED NUCLEOSIDE DERIVATIVES - The present invention relates to 2′-allene-substituted nucleoside derivatives of the general formula (I):09-20-2012
201300782172'-CHLOROACETYLENYL SUBSTITUTED NUCLEOSIDE DERIVATIVES - The present invention relates to 2′-chloroacetylenyl-substituted nucleoside derivatives of the general formula (I):03-28-2013
201301656416,11-BRIDGED BIARYL MACROLIDES - The present invention discloses compounds of formula I, II or X, or pharmaceutically acceptable salts, esters, or prodrugs thereof:06-27-2013
20130183267CYCLOSPORIN ANALOGUES FOR PREVENTING OR TREATING HEPATITIS C INFECTION - The present invention relates to cyclosporin analogues having antiviral activity against HCV and useful in the treatment of HCV infections. More particularly, the invention relates to novel cyclosporin analogue compounds, compositions containing such compounds and methods for using the same, as well as processes for making such compounds.07-18-2013
20130315864MACROCYCLIC NUCLEOSIDE PHOSPHORAMIDATE DERIVATIVES - The present invention provides nucleoside phosphoramidate compounds of Formula I,11-28-2013
201401354856-11 BICYCLIC KETOLIDE DERIVATIVES - The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof:05-15-2014
20140154208Novel [N-Me-4-hydroxyleucine]-9-Cyclosporin Analogues for Treatment and Prevention of Hepatitis C Infection - The present invention relates to novel cyclosporine analogues having antiviral activity against HCV and useful in the treatment of HCV infections. More particularly, the invention relates to novel cyclosporine analogue compounds, compositions containing such compounds and methods for using the same, as well as processes for making such compounds.06-05-2014
201401877806,11-BRIDGED BIARYL MACROLIDES - The present invention discloses compounds of formula I, II or X, or pharmaceutically acceptable salts, esters, or prodrugs thereof:07-03-2014
20140187793PROCESSES FOR THE PREPARATION OF 5-AZASPIRO[2.4]HEPTANE-6-CARBOXYLIC ACID AND ITS DERIVATIVES - The present invention relates generally to an improved process for the preparation of 5-azaspiro[2.4]heptane-6-carboxylic acid and its derivatives which are useful intermediates in the synthesis of biologically active molecules, especially in the synthesis of hepatits C virus NS5A inhibitors. In particular, the present invention relates to processes and intermediates for the preparation of compounds of formulae (Ia), (Ib) and (Ic):07-03-2014
20140194350MACROCYCLIC PROLINE DERIVED HCV SERINE PROTEASE INHIBITORS - The present invention discloses compounds of Formula I or pharmaceutically acceptable salts, esters, or prodrugs thereof:07-10-2014
201402199585, 6-D2 URIDINE NUCLEOSIDE/TIDE DERIVATIVES - In one aspect, the invention provides compounds represented by Formula I,08-07-2014
20140287992MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS - The present invention relates to novel macrocyclic compounds and methods of treating a hepatitis C infection in a subject in need of such therapy with said macrocyclic compounds. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient.09-25-2014
20140316143PROCESSES FOR THE PREPARATION OF NOVEL BENZIMIDAZOLE DERIVATIVES - The present invention relates to processes and intermediates for the preparation of novel benzimidazole derivatives, especially in the synthesis of hepatitis C virus NS5A inhibitors. In particular, the present invention relates to processes and intermediates for the preparation of compounds of formulae (I-a):10-23-2014
20150056165NOVEL CYCLOSPORIN ANALOGUES FOR PREVENTING OR TREATING HEPATITIS C INFECTION - The present invention relates to novel cyclosporine analogues having antiviral activity against HCV and useful in the treatment of HCV infections. More particularly, the invention relates to novel cyclosporine analogue compounds, compositions containing such compounds and methods for using the same, as well as processes for making such compounds.02-26-2015

Patent applications by Guoqiang Wang, Belmont, MA US

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