Patent application number | Description | Published |
20090169576 | INFLUENZA COMBINATORIAL ANTIGEN VACCINE - The invention provides a combinatorial influenza vaccine composition for use in providing prophylactic protection in humans against influenza viruses or animals, and a method of producing the vaccine. | 07-02-2009 |
20090176654 | Universal fibronectin type III binding-domain libraries - Walk-through mutagenesis and natural-variant combinatorial fibronectin Type III (FN3) polypeptide libraries are described, along with their method of construction and use. Also disclosed are a number of high binding affinity polypeptides selected by screening the libraries against a variety of selected antigens. | 07-09-2009 |
20090215639 | Method of Producing Human IgG Antibodies with Enhanced Effector Functions - A method for generating human IgG | 08-27-2009 |
20090299046 | SELF-ASSEMBLING OLIGONUCLEOTIDES AND METHODS - A composition comprising individual single-stranded oligonucleotides capable of self assembling to form a pair of complementary, substantially contiguous single strands of a double-stranded nucleic acid filament, and a method for forming such filaments are disclosed. | 12-03-2009 |
20100152063 | UNIVERSAL FIBRONECTIN TYPE III BINDING-DOMAIN LIBRARIES - Walk-through mutagenesis and natural-variant combinatorial fibronectin Type III (FN3) polypeptide libraries are described, along with their method of construction and use. Also disclosed are a number of high binding affinity polypeptides selected by screening the libraries against a variety of selected antigens. | 06-17-2010 |
20110021746 | UNIVERSAL FIBRONECTIN TYPE III BINDING-DOMAIN LIBRARIES - Fibronectin Type III (FN3) polypeptide libraries are described, along with their use in identifying fibronectin-type binding peptides having hign binding affinities, e.g., greater than 300 nM, for VEGFR2 or Axl proteins. | 01-27-2011 |
20110124527 | UNIVERSAL FIBRONECTIN TYPE III BINDING-DOMAIN LIBRARIES - Walk-through mutagenesis and natural-variant combinatorial fibronectin Type III (FN3) polypeptide libraries are described, along with their method of construction and use. Also disclosed are a number of high binding affinity polypeptides selected by screening the libraries against a variety of selected antigens. | 05-26-2011 |
20110245108 | Universal Antibody Libraries - Universal antibody libraries are described which are synthetic and derived from expressed human antibody sequences selected accordingly to certain criteria, for example, that the sequences are derived from naturally-occurring antibodies expressed in response to a certain antigen class (e.g., small molecule, polysaccharide, peptide, or protein) and having CDR regions engineered for optimal diversity. Methods for making and screening such libraries for isolating therapeutics suitable for treating disease are also disclosed. | 10-06-2011 |
20140135474 | UNIVERSAL FIBRONECTIN TYPE III BINDING-DOMAIN LIBRARIES - Fibronectin Type III (FN3) polypeptide libraries are described, along with their use in identifying fibronectin-type binding peptides having high binding affinities, e.g., greater than 300 nM, for VEGFR2 or Axl proteins. | 05-15-2014 |
20140206576 | UNIVERSAL FIBRONECTIN TYPE III BINDING-DOMAIN LIBRARIES - Walk-through mutagenesis and natural-variant combinatorial fibronectin Type III (FN3) polypeptide libraries are described, along with their method of construction and use. Also disclosed are a number of high binding affinity polypeptides selected by screening the libraries against a variety of selected antigens. | 07-24-2014 |