Gordon A.
Gordon A. Anderson, Benton City, WA US
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20100161530 | METHOD FOR ENHANCED ACCURACY IN PREDICTING PEPTIDES ELUTION TIME USING LIQUID SEPARATIONS OR CHROMATOGRAPHY - A method for predicting the elution time of a peptide in chromatographic and electrophoretic separations by first providing a data set of known elution times of known peptides, then creating a plurality of vectors, each vector having a plurality of dimensions, and each dimension representing positional information about at least a portion of the amino acids present in the known peptides. A hypothetical vector is then created by assigning dimensional values for at least one hypothetical peptide, and a predicted elution time for the hypothetical vector is created by performing at least one multivariate regression fitting the hypothetical peptide to the plurality of vectors. Preferably, the multivariate regression is accomplished by the use of an artificial neural network and the elution times are first normalized using linear regression. | 06-24-2010 |
20120261570 | MICROCHIP AND WEDGE ION FUNNELS AND PLANAR ION BEAM ANALYZERS USING SAME - Electrodynamic on funnels confine, guide, or focus ions in gases using the Dehmelt potential of oscillatory electric field. New funnel designs operating at or close to atmospheric gas pressure are described. Effective on focusing at such pressures is enabled by fields of extreme amplitude and frequency, allowed in microscopic gaps that have much higher electrical breakdown thresholds in any gas than the macroscopic gaps of present funnels. The new microscopic-gap funnels are useful for interfacing atmospheric-pressure ionization sources to mass spectrometry (MS) and on mobility separation (IMS) stages including differential IMS or FAIMS, as well as IMS and MS stages in various configurations. In particular, “wedge” funnels comprising two planar surfaces positioned at an angle and wedge funnel traps derived therefrom can compress on beams in one dimension, producing narrow belt-shaped beams and laterally elongated cuboid packets. This beam profile reduces the ion density and thus space-charge effects, mitigating the adverse impact thereof on the resolving power, measurement accuracy, and dynamic range of MS and IMS analyzers, while a greater overlap with coplanar light or particle beams can benefit spectroscopic methods. | 10-18-2012 |
20140299766 | ION MANIPULATION DEVICE - An ion manipulation method and device is disclosed. The device includes a pair of substantially parallel surfaces. An array of inner electrodes is contained within, and extends substantially along the length of, each parallel surface. The device includes a first outer array of electrodes and a second outer array of electrodes. Each outer array of electrodes is positioned on either side of the inner electrodes, and is contained within and extends substantially along the length of each parallel surface. A DC voltage is applied to the first and second outer array of electrodes. A RF voltage, with a superimposed electric field, is applied to the inner electrodes by applying the DC voltages to each electrode. Ions either move between the parallel surfaces within an ion confinement area or along paths in the direction of the electric field, or can be trapped in the ion confinement area. | 10-09-2014 |
20150076343 | ION MANIPULATION DEVICE TO PREVENT LOSS OF IONS - An ion manipulation method and device to prevent loss of ions is disclosed. The device includes a pair of surfaces. An inner array of electrodes is coupled to the surfaces. A RF voltage and a DC voltage are alternately applied to the inner array of electrodes. The applied RF voltage is alternately positive and negative so that immediately adjacent or nearest neighbor RF applied electrodes are supplied with RF signals that are approximately 180 degrees out of phase. | 03-19-2015 |
Gordon A. Bekkala, Cokato, MN US
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20140256234 | System for Dispensing Abrasive Particles in a Liquid Jet Apparatus - A submersible liquid jet apparatus is provided for a system with a portable liquid jet tool that may be handled by human divers or remotely operated vehicles (ROV). The present apparatus facilitates the portability of a liquid jet tool with a support unit supplying high pressure working liquid and pressurized hydraulic fluid. The apparatus further provides portable delivery of an abrasive suspension to enhance the effectiveness of the high pressure working liquid. | 09-11-2014 |
Gordon A. Bergfors, Wake Forest, NC US
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20100194013 | CNC MATERIAL PROCESSING SYSTEM WITH WORKPIECE TRAVEL - A CNC system including a travelling drive bar assembly for support of material to be processed. A CNC system including a cutting tool operates on a work piece in at least three axes, with a gantry across the machine that a carriage moves along and a tool that moves vertically on the carriage. A drive bar, oriented perpendicularly to the gantry and to a vertical axis, may travel to support and move the workpiece along its line of orientation. The drive bar may include an elongated structural member, two tracks mounted longitudinally to the elongated member on opposite sides of the elongated member, and a rack, adapted to accept a pinion to urge the drive bar to move, also mounted longitudinally to the elongated member. Guide wheels may receive the tracks to support and align the drive bar. Rollers may further support material that is mounted to the drive bar. | 08-05-2010 |
Gordon A. Drukier, New Haven, CT US
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20130259389 | IMAGE ANALYSIS BY OBJECT ADDITION AND RECOVERY - The invention described herein is generally directed to methods for analyzing an image. In particular, crowded field images may be analyzed for unidentified, unobserved objects based on an iterative analysis of modified images including artificial objects or removed real objects. The results can provide an estimate of the completeness of analysis of the image, an estimate of the number of objects that are unobserved in the image, and an assessment of the quality of other similar images. | 10-03-2013 |
20140136135 | CROWD-SOURCED HARDWARE CALIBRATION - Systems and methods for calibrating multiple electronic devices are described herein. Such methods may include obtaining, by a processor, data from a plurality of reference electronic devices, analyzing, by a processor, the data and calibrating, by the processor, the electronic device based on the analyzed data obtained from the plurality of reference electronic devices. | 05-15-2014 |
20140254944 | IMAGE ANALYSIS BY OBJECT ADDITION AND RECOVERY - The invention described herein is generally directed to methods for analyzing an image. In particular, crowded field images may be analyzed for unidentified, unobserved objects based on an iterative analysis of modified images including artificial objects or removed real objects. The results can provide an estimate of the completeness of analysis of the image, an estimate of the number of objects that are unobserved in the image, and an assessment of the quality of other similar images. | 09-11-2014 |
20140323157 | SYSTEMS AND METHODS FOR HAZARDOUS MATERIAL SIMULATIONS AND GAMES USING INTERNET-CONNECTED MOBILE DEVICES - Embodiments of the invention are directed to systems, devices, and methods for using mobile devices to detect a simulated source, and games and training exercises using these systems, devices, and methods. In some embodiments, the source may be a simulated hazardous material that emits energy, particles, or vapors that can also be simulated by the mobile devices. In such embodiments, the systems, devices, and methods can be used to simulate an incident involving the release of hazardous materials such as, for example, a chemical or radioactive material spill or attack by chemical, biological, nuclear, or radioactive (dirty bomb) weapons. In other embodiments, the system can be used to simulate an object used in a game such as a ball, puck, or goal and monitor movement of the object and players using a mobile device. | 10-30-2014 |
Gordon A. Ebanks, New York, NY US
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20100094869 | Method of Presenting Search Results to a User of a Social Network Site - Method of presenting search results to a user of a social network site on the Internet, in which each user of the social network site has a user profile with information regarding the user, includes obtaining content items satisfying a search of information on the Internet by a first user. The content items are ranked as a function of the information in the user profile of the first user such that the content items which are related to the information in the user profile of the first user are ranked higher than the content items which are unrelated to the information in the user profile of the first user. The content items according to ranking are then transferred to a display of the first user via the Internet such that higher ranked content items are displayed on the display prior to lower ranked content items being displayed on the display. | 04-15-2010 |
20120005201 | Method of Ranking Search Results Presented to a User of a Social Network Site - Method of presenting search results to a user of a social network site on the Internet, in which each user of the social network site has a user profile with information regarding the user, includes obtaining content items satisfying a search of information on the Internet by a first user. The content items are ranked as a function of the information in the user profile of the first user such that the content items which are related to the information in the user profile of the first user are ranked higher than the content items which are unrelated to the information in the user profile of the first user. The content items according to ranking are then transferred to a display of the first user via the Internet such that higher ranked content items are displayed on the display prior to lower ranked content items being displayed on the display. | 01-05-2012 |
20140365482 | Method of Presenting Internet Search Results - A method of presenting Internet search results includes obtaining Internet search results in response to a search request from a first user of a site. Users of the site have profiles with information regarding the users. The first user has a profile with information associating certain of the users to the first user. The search results are ranked such that the search results related to the information regarding the users associated with the first user are ranked highest. The search results are displayed on a display according to the ranking | 12-11-2014 |
Gordon A. Jamieson, Jr., Arlington, MA US
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20090163564 | Translational Dysfunction Based Therapeutics - Provided are methods and compositions for inhibiting eukaryotic translation initiation factor eIF4E. Such methods and compositions may be used alone or in conjunction with other therapies, such as gene therapies, for inhibiting cell proliferation and/or treating cancer. | 06-25-2009 |
20100317043 | MASS SPECTROMETRY ASSAY FOR eIF4E AND eIF4E REGULON ACTIVITY - Provided is a highly sensitive high throughput mass spectrometry-based quantitative assay for 4E/4E regulon pathway proteins has been developed which provides for single sample multiplexed analysis, as well as the analysis of protein phosphorylation states. It may be adapted for use as the first single sample analytical method of the 4E/4E regulon biological pathway. | 12-16-2010 |
20110319295 | MASS SPECTROMETRY ASSAY FOR eIF4E AND eIF4E REGULON ACTIVITY - Provided is a highly sensitive high throughput mass spectrometry-based quantitative assay for 4E/4E regulon pathway proteins has been developed which provides for single sample multiplexed analysis, as well as the analysis of protein phosphorylation states. It may be adapted for use as the first single sample analytical method of the 4E/4E regulon biological pathway. | 12-29-2011 |
20140199692 | TRANSLATIONAL DYSFUNCTION BASED THERAPEUTICS - Provided are methods and compositions for inhibiting eukaryotic translation initiation factor eIF4E. Such methods and compositions may be used alone or in conjunction with other therapies, such as gene therapies, for inhibiting cell proliferation and/or treating cancer. | 07-17-2014 |
Gordon A. Janaway, Carlsbad, CA US
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20140053095 | Visualization Tool for qPCR Genotyping Data - Systems and methods are used to display data obtained from a qPCR instrument. Each of two or more samples is probed with a first labeling probe and a second labeling probe. A first data set is received from a qPCR instrument at a first cycle number that includes for each sample a first labeling probe intensity, and a second labeling probe intensity. A second data set is received at a second cycle number that includes for each sample a first labeling probe intensity and a second labeling probe intensity. A first plot of first labeling probe intensity as a function of second labeling probe intensity is created using the first data set. A second plot of first labeling probe intensity as a function of second labeling probe intensity is created using the second data set. The first plot and the second plot are displayed in response to user defined input to provide dynamic and real-time analysis of genotyping data. | 02-20-2014 |
Gordon A. Janaway, Castro Valley, CA US
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20140236496 | Methods and Systems for Visualizing and Evaluating Data - A computer-implemented method of generating a digital polymerase chain reaction (dPCR) result is provided. The method includes detecting a first set of emission data from a plurality of samples, each included in a sample region of a plurality of sample regions, at a first time during an amplification period. The method further includes determining a positive or negative amplification determination for each sample of the plurality of samples based in part on the first set of emission data. A dPCR result is generated based on the positive or negative amplification determinations for the plurality of samples. | 08-21-2014 |
Gordon A. Janaway, Hayward, CA US
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20100228496 | Methods for the Determination of a Copy Number of a Genomic Sequence in a Biological Sample - Methods for the determination of a copy number of a target genomic sequence; either a target gene or genomic sequence of interest, in a biological sample are described. Various methods utilize a model drawn from a probability density function (PDF) for the assignment of a copy number of a target genomic sequence in a biological sample. Additionally, the methods provide for the determination of a confidence value for a copy number assigned to a sample based on attributes of the sample data. Accordingly, the various methods for the determination of a copy number provide the end user with significant information for the evaluation of a copy number of a target genomic sequence; either a gene or genomic sequence of interest. | 09-09-2010 |
20110200989 | SINGLE MOLECULE NUCLEIC ACID SEQUENCING USING MULTIPHOTON FLUORESCENCE EXCITATION - A system for detection of nucleic acids can include an excitation source configured to transmit excitation energy to a reaction site including a single molecule of nucleic acid reacted with a two-photon absorption moiety. The system also can include an optical system configured to focus the excitation energy transmitted from the excitation source to a focal region containing the reaction site, wherein said excitation energy within the focal region is sufficient to cause two-photon absorption by the two-photon absorption moiety. The system can further include a detector configured to detect emissions generated at the reaction site resulting from two-photon absorption of the excitation energy by the two-photon absorption moiety. | 08-18-2011 |
20140248623 | System and Method for Determining Copies-per-Unit-Volume Using PCR and Flow Control of Droplets - Methods and systems for quantification of a target nucleic acid in a sample are provided. The method includes forming a plurality of discrete sample portions. Each of the plurality of discrete sample portions comprising a portion of the sample, and a reaction mixture. The method further includes amplifying the plurality of discrete sample portions to form a plurality of discrete processed sample portions. At least one discrete processed sample portion containing nucleic acid amplification reaction products. Fluorescence signals are detected from the at least one of the plurality of discrete processed sample portions to determine a presence of the at least one target nucleic acid. The method also includes determining the respective volumes of the plurality of the plurality of discrete processed sample portions, and estimating the number of copies-per-unit-volume of the at least one target nucleic acid in the sample. Estimating the number of copies-per-unit-volume is based on the number of discrete processed sample portions determined to contain the at least one target nucleic acid therein. | 09-04-2014 |
Gordon A. Jones, Lancashire GB
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20120286152 | ION SOURCE WITH SURFACE COATING - A mass spectrometer includes an Electron Impact (“EI”) or a Chemical Ionisation (“CI”) ion source, and the ion source includes a first coating or surface. The first coating or surface is formed of a metallic carbide, a metallic boride, a ceramic or DLC, or an ion-implanted transition metal. | 11-15-2012 |
20120292500 | MASS SPECTROMETER SAMPLING CONE WITH COATING - A mass spectrometer includes an ion source, which includes a coating or surface formed of a metallic carbide, a metallic boride, a ceramic or DLC, or an ion-implanted transition metal. | 11-22-2012 |
20130277550 | Mass Spectrometer Sampling Cone With Coating - A sampling cone of a mass spectrometer is disclosed having a metallic boride coating such as titanium diboride. | 10-24-2013 |
20130299691 | Ion Source With Surface Coating - A mass spectrometer includes an Electron Impact (“EI”) or a Chemical Ionisation (“CI”) ion source, and the ion source includes a first coating or surface. The first coating or surface is formed of a metallic carbide, a metallic boride, a ceramic or DLC, or an ion-implanted transition metal. | 11-14-2013 |
Gordon A. Olsen, Tigard, OR US
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20140120857 | MAGNITUDE AND PHASE RESPONSE CALIBRATION OF RECEIVERS - An integrated calibrator provides for magnitude and phase response calibration of RF receivers to produce amplitude flatness and phase linearity across the frequency range of the RF receiver by using a simple square law diode detector and a frequency-stepped two-tone source. A two-tone source generator provides two sinusoidal signals separated by a specified frequency delta about a center frequency. The center frequency is stepped across the bandwidth of the RF receiver. At each center frequency the two sinusoidal signals are input to the RF receiver and to the diode detector. The two sinusoidal signals are processed by both the receiver path and the calibrator path, and the results are used by the calibrator to generate coefficients for a correction filter in the receiver path at each of the stepped center frequencies. | 05-01-2014 |
20140139279 | AUTOMATIC QUADRATURE NETWORK WITH PHASE AND AMPLITUDE DETECTION - An automatic quadrature network with amplitude and phase detection produces quadrature signals for an input oscillator signal, the quadrature signals being equal in amplitude and having ideal quadrature phase between them. An RC circuit provides one quadrature path, and a CR circuit provides another quadrature path. The outputs from the RC/CR circuits are amplitude detected to produce an amplitude control signal. The outputs also are amplitude limited, and the phase between the limiter outputs is detected to produce a phase control signal. The amplitude and phase control signals are combined to generate respective control signals for the RC/CR circuits to automatically align them so that the quadrature signals are of equal amplitude and ideal quadrature phase. | 05-22-2014 |
Gordon A. Putney, Lake Geneva, WI US
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20140338942 | Ball Deflecting Chamfer - A cam shaft is disclosed having an asymmetric chamfer for guiding a ball bearing deeper into a cam shaft groove to avoid ball loss when an immediate deceleration force is applied. The chamfer spaces the ball from an opening in the front face of a hammer that moves axially relative to the cam shaft when a tool having the cam shaft and hammer is dropped. The ball is therefore less likely to escape through the front opening of the hammer when the impact wrench is dropped. | 11-20-2014 |
Gordon A. Stewart, Sebastopol, CA US
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20100010682 | IRRIGATION SYSTEM - A technique for controlling an irrigation system is disclosed. The technique comprises receiving landscape information, receiving environmental information, deriving an irrigation schedule based on the landscape information and the environmental information, and sending the irrigation schedule to an irrigation control unit. | 01-14-2010 |
Gordon A. Uehling, Iii, Cresskill, NJ US
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20110124444 | VIDEO-BASED SYSTEM FOR TENNIS TRAINING INCORPORATING MATS - In accordance with the invention, the inventive mat comprises a planar member. A first marking is disposed on the planar member corresponding to the position of the ball of the foot of the first foot at a first swing first point in time during the execution of a first tennis swing. The first swing first point in time is relatively proximate to the commencement of the execution of the first tennis swing. The first foot is the right foot of a right-hand dominant player or the left foot of a left-hand dominant player practicing a two-handed backhand. The first marking may comprise an indication of the sole of a first shoe and indicate the placement of the heel of the first shoe. A second marking is disposed on the planar member corresponding to the position of the sole of the second foot at the first swing first point in time during the execution of the first tennis swing. A third marking is disposed on the planar member corresponding to the position of the first foot at a first swing second point in time during the execution of the first tennis swing. The second marking corresponds to the position of the second foot at the first swing second point in time during the execution of the first tennis swing. The first swing second point in time is after the first swing first point in time. | 05-26-2011 |
20110124445 | VIDEO-BASED SYSTEM FOR TENNIS TRAINING - The inventive system comprises a first plurality of cameras disposed around a first point in a practice area to generate a plurality of first images of an individual positioned at the first point in the course of the execution of a swing by the individual. A second plurality of cameras is disposed around a second point in a practice area, the second point being displaced from the first point. The second plurality of cameras is symmetrically positioned with respect to the first plurality of cameras about an axis defined by the position of a first theoretical line positioned between the first and second plurality of cameras, and transverse to a second theoretical line extending between the first and second plurality of cameras. The second plurality of cameras generating a plurality of second images of an individual positioned at the second point in the course of the execution of a swing by the individual. The inventive mat is placed in the practice area at a position below that damaged by the cameras, in order to guide the movements of an individual practicing tennis swings. | 05-26-2011 |