Goldstein, US
Adam Goldstein US
Adam Goldstein, Las Vegas, NV US
Adam S. Goldstein, New Market, MD US
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20090215126 | NUCLEIC ACID-FREE THERMOSTABLE ENZYMES AND METHODS OF PRODUCTION THEREOF - The present invention provides thermostable enzymes, such as DNA polymerases and restriction endonucleases, that are substantially free from contamination with nucleic acids. The invention also provides methods for the production of these enzymes, and kits comprising these enzymes which may be used in amplifying or sequencing nucleic acid molecules, including through use of the polymerase chain reaction (PCR). | 08-27-2009 |
20110281276 | NUCLEIC ACID-FREE THERMOSTABLE ENZYMES AND METHODS OF PRODUCTION THEREOF - The present invention provides thermostable enzymes, such as DNA polymerases and restriction endonucleases, that are substantially free from contamination with nucleic acids. The invention also provides methods for the production of these enzymes, and kits comprising these enzymes which may be used in amplifying or sequencing nucleic acid molecules, including through use of the polymerase chain reaction (PCR). | 11-17-2011 |
Alan Goldstein, Marietta, GA US
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20090248506 | MERCHANT FUNDED REWARDS NETWORK IMPLEMENTING CARDHOLDER LOYALTY REBATE PROGRAM - A system and method for implementing a program such as a loyalty program. An account (e.g., card) system includes a plurality of participating account holders (e.g., cardholders) of an issuer, a plurality of non-participating account holders (e.g., cardholders) of the issuer and of other issuers, a plurality of non-preferred merchants of the issuer and of other issuers and a plurality of preferred merchants of the issuer. A filter is used to evaluate transactions to identify qualifying program transactions involving both a participating account holders (e.g., cardholders) of the issuer and a preferred merchant of the issuer. Rebates are provided for identified, qualifying program transactions. | 10-01-2009 |
Albert M. Goldstein, Farmington Hills, MI US
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20100084125 | MICROCLIMATE CONTROL SYSTEM - A heating/cooling garment is provided that comprises a microclimate system, as well as methods of manufacturing and using same. | 04-08-2010 |
Andrew H. Goldstein, Branford, CT US
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20100152526 | Blood pump device and method of producing - A pumping system for blood for a patient includes a sensorless pump having no sensors disposed in the pump itself for moving the blood, a motor and a blood transport port through which blood is received from the patient and is pumped into the patient. The system also includes a controller connected to the pump for controlling the pump so a desired flow rate of blood can be maintained by the pump. | 06-17-2010 |
Andrew S. Goldstein, Portland, OR US
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20090170072 | DEVICE FOR COLLECTION AND ASSAY OF ORAL FLUIDS - A device for collecting and transporting aqueous fluid from the oral cavity to a lateral chromatographic strip for test is disclosed. The lateral chromatographic strip is placed within and extend along a cavity defined in a housing. At least one inspection site to the lateral chromatographic strip is provided to enable inspection of selected sites on the lateral chromatographic strip for test results. A porous wick material protrudes from the housing to a collection site exterior of the housing at one end and communicates to the lateral chromatographic strip at the other end. The porous wick material has particulate construction, the particles adsorbing aqueous oral fluid to transport the fluid from the mouth to the lateral chromatographic strip without substantial absorption. The particles of the porous wick material are bound together to define a continuous interstitial volume for the flow of oral fluid to be transported and are treated to be hydrophilic to the adsorbed oral fluids. The porous wick material readily releases oral fluid to the lateral chromatographic strip. Prevention of reverse flow to the oral cavity from the lateral chromatographic strip naturally occurs due to the circuitous flow path of the porous wick material. A bite plate is coupled to the housing and insertable between the teeth of the patient to position the porous wick in the oral cavity for collecting the oral fluid. The bite plate is typically held in place by the occlusal force of the teeth, preferably the molars and/or the bicuspids, to position the porous wick in the buccal space. By observing the lateral chromatographic strip while the test device is in the mouth immediate test results are obtained. | 07-02-2009 |
20100239458 | COLLECTION DEVICE FOR ASSAY OF ORAL FLUIDS - An apparatus and process for transporting aqueous fluid from the oral cavity to a lateral chromatographic strip for test is disclosed. A lateral chromatographic strip is placed within a cavity defined in a housing. The lateral chromatography strip extends within the cavity and is disposed along the housing to an inspection site. At least one inspection site to the lateral chromate phic strip is provided to enable inspection of selected sites on the lateral chromatographic strip for test results. A porous wick material protrudes from the housing to a collection site exterior of the housing at one end and communicates to the lateral chromatographic strip at the other end. This porous wick material has particulate construction, the particles adsorbing aqueous oral fluid to transport the fluid from the mouth to the lateral chromatographic strip without substantial absorption. The particles of the porous wick material are bound together to define a continuous interstitial volume for the flow of oral fluid to be transported and are treated to be hydrophilic to the adsorbed oral fluids. The porous wick material readily releases oral fluid to the lateral chromatographic strip. Prevention of reverse flow to the oral cavity from the lateral chromatographic strip naturally occurs due to the circuitous flow path of the porous wick material. By observing the lateral chromatographic strip while the entire test device is in the mouth immediate test results are obtained. | 09-23-2010 |
20120083711 | DIAGNOSTIC DEVICE AND METHOD FOR SENSING HYDRATION STATE OF A MAMMALIAN SUBJECT - Timed sensing of collection of saliva in a liquid collection element of predetermined volumetric capacity may be used to determine salivary secretion rate, as may be indicative of state of euhydration or dehydration. Sensing of salivary flow rate may be further augmented by sensing concentration of at least one analyte in saliva (e.g., with an immunochromatographic assay performed in a lateral flow device) in order to determine a state of euhydration or dehydration. Production of saliva may be stimulated, and collected saliva may be analyzed to generate an analyte detection signal that indicative of presence and/or correlative of concentration of at least one analyte in the collected saliva to sense a state of euhydration or dehydration. | 04-05-2012 |
20120149124 | DEVICE FOR COLLECTION AND ASSAY OF ORAL FLUIDS - A method and a device for collection and assay of oral fluids are disclosed. The method places an assay device into an oral cavity, removes the device, and determines the presence or absence of an analyte. The assay device comprises an assay portion housing a lateral flow assay strip, a neck portion extending from the assay portion and forming a channel for fluid delivery to the assay strip; a collection strip in fluid communication with the lateral flow assay strip; and a blocking strip coupled between and in flow communication with the lateral flow assay strip and the collection strip. The channel is defined by a narrow part proximal to the assay portion and a part which receives oral fluid and has a substantially wider channel width. The collection strip has a first portion disposed within the channel and a second portion protruding outwardly from the neck opening. | 06-14-2012 |
20120289863 | DIAGNOSTIC DEVICE AND METHOD FOR SENSING HYDRATION STATE OF A MAMMALIAN SUBJECT - Timed sensing of collection of saliva in a liquid collection element of predetermined volumetric capacity may be used to determine salivary secretion rate, as may be indicative of state of euhydration or dehydration. Sensing of salivary flow rate may be further augmented by sensing concentration of at least one analyte in saliva (e.g., with an immunochromatographic assay performed in a lateral flow device) in order to determine a state of euhydration or dehydration. Production of saliva may be stimulated, and collected saliva may be analyzed to generate an analyte detection signal that indicative of presence and/or correlative of concentration of at least one analyte in the collected saliva to sense a state of euhydration or dehydration. | 11-15-2012 |
Arthur Allen Goldstein, Mayfield Village, OH US
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20090151845 | PNEUMATIC TIRE - A pneumatic radial tire has a chipper in place of a traditional apex, the chipper located between a carcass main portion and turnup portion. The chipper layer may be composed of a chopped carbon fiber and aramid composite reinforced elastomeric layer. The tire sidewalls have a radial height SH and a section width SW located within a range of 0.4 to 0.44 of the sidewall radial height SH measured from the bead core. The section width SW may further be located within a range of 0.1″ to 0.3″ inches from a radially outward end of the chipper layer in a radial direction. The tread may of a dual layer construction, having a radially inward first layer formed of a relatively low rolling resistance compound and a radially outward second layer formed of a compound containing silica. | 06-18-2009 |
20110114240 | PNEUMATIC TIRE - A pneumatic radial tire having a circumferentially extending equatorial plane of the tire, the tire comprising a carcass, a tread radially outward of the carcass, the carcass comprising at least one carcass reinforcing ply, opposing bead portions, and opposing sidewalls, the carcass reinforcing ply having a main portion extending between the opposing bead portions and a pair of turnup portions, each turnup portion extending from one end of the main portion, each bead portion having a bead core, and a reinforcement cavity outward of each bead core, the cavity located between the main portion and one turnup portion of the at least one reinforcing ply, the tire characterized by: | 05-19-2011 |
20120285590 | TIRE WITH TREAD HAVING BASE LAYER COMPRISED OF DIVERSE ZONED RUBBER COMPOSITIONS - The invention relates to a tire having a rubber tread comprised of cap/base construction where the tread outer cap rubber layer contains the running surface of the tread and the tread base rubber layer underlies the tread cap layer wherein the base layer provides a transition zone between the tread cap layer and the remainder of the tire carcass and is not intended to be ground-contacting. For this invention, the tread base rubber layer is comprised of three distinct zones, namely a circumferential annular central rubber zone positioned between two lateral annular rubber zones. In one aspect, the rubber tread cap layer and zoned rubber tread base layer are co-extruded together to form an integral tread rubber composite. | 11-15-2012 |
20130126060 | STIFFNESS ENHANCED TREAD - A pneumatic tire includes a tread base comprised of a first material, a tread cap comprised of a second material, and a plurality of plugs comprised of a third material. The tread cap is disposed radially outward of the tread base and in operational contact with a ground surface. The plurality of plugs are disposed at least partially within the tread cap. The plurality of plugs yield a tread stiffness in one direction greater than stiffness in at least one other direction. | 05-23-2013 |
20140114558 | VEHICLE WEIGHT AND CENTER OF GRAVITY ESTIMATION SYSTEM AND METHOD - A load estimation system and method for estimating vehicle load includes a tire rotation counter for generating a rotation count from rotation of a tire; apparatus for measuring distance travelled by the vehicle; an effective radius calculator for calculating effective radius of the tire from the distance travelled and the rotation count; and a load estimation calculator for calculating the load carried by the vehicle tire from the effective radius of the tire. A center of gravity height estimation may be made from an estimated total load carried by the tires supporting the vehicle pursuant to an estimation of effective radius for each tire and a calculated load carried by each tire from respective effective radii. | 04-24-2014 |
Avery N. Goldstein, Troy, MI US
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20100112396 | FIELD HYDROGEN GENERATION SYSTEM - A field hydrogen generation system. Includes a flexible housing transparent to visible light and a photoelectrochemical cell adapted to be received within a volume of the housing. A quantity of feedstock liquid within the housing is in contact with said photoelectrochemical cell. A conduit is in fluid communication between the volume of the housing and a hydrogen collection vessel. | 05-06-2010 |
Barry Goldstein, Bala Cynwyd, PA US
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20100056445 | ADIPONECTIN FOR THE TREATMENT AND DIAGNOSIS OF ALBUMINURIA - Disclosed are methods relating to the treatment and/or prevention of kidney disorders, especially kidney disorders characterized by or involving albuminuria. Methods described include the administration of an adiponectin polypeptide or a nucleic acid encoding such a polypeptide to treat or prevent the development of albuminuria. Also described are methods in which adiponectin is measured as a predictor of a subject's likelihood of having or developing a kidney disorder characterized by or involving albuminuria. Also described are methods of treating or preventing a kidney disorder involving administering an AMPK agonist and/or an inhibitor of Nox4 activity. | 03-04-2010 |
Brett Goldstein, Potomac, MD US
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20110030539 | Device and Method for Controlled Breaching of Reinforced Concrete - A breaching apparatus includes an impactor element and a self-contained energy source. The self-contained energy source enables the impactor element to impact a first surface of a structure. The impactor element is configured to transmit a localized shock wave through the structure upon impact. The self-contained energy source is capable of accelerating the impactor element to a velocity sufficient to induce spalling at a second surface of the structure. Multiple breaching apparatuses can be supported by a frame to facilitate simultaneous or successive breaching of the structure. The breaching apparatus can be used in a method to breach a concrete structure. | 02-10-2011 |
Brett Goldstein, Kensington, MD US
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20100038068 | CENTRALIZER-BASED SURVEY AND NAVIGATION DEVICE AND METHOD - A Centralizer based Survey and Navigation (CSN) device designed to provide borehole or passageway position information. The CSN device can include one or more displacement sensors, centralizers, an odometry sensor, a borehole initialization system, and navigation algorithm implementing processor(s). Also, methods of using the CSN device for in-hole survey and navigation. | 02-18-2010 |
Bridget A. Goldstein, Waikoloa, HI US
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20130012234 | Systems and Methods for Position Tracking and Reporting of Objects - Geographic location and environmental conditions of a tracking target are reported by a position tracking and reporting (“PTR”) device. Reports are aggregated and stored by a server system, which also provides access to the information for interactive and automatic programmatic use. A mobile phone (smartphone) interface allows system conditions to be examined, and PTR device operating envelope to be modified. | 01-10-2013 |
Dahna Goldstein, Washington, DC US
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20090117529 | Grant administration system - A method and system are disclosed for facilitating the completion of a questionnaire. A storage medium stores a plurality of questions and associated answers. Similar questions are linked. An interface presents to a user through a computer network a presented question as part of a questionnaire to be completed. The interface also presents to the user answers associated with similar questions linked to the presented question. Upon user selection, an answer to a similar question is stored as an answer to the selected question. The user may modify the answer. The method and system may present additional questions and answers associated with similar questions linked to the additional question. A user may have access to stored questions, add questions, and link similar questions. Answers to questions may be stored before the user completes the questionnaire. The questionnaire may include fields populated with information previously supplied by the user without user selection. The storage medium may be a database. | 05-07-2009 |
Daniel E. Goldstein, Mundelein, IL US
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20130048660 | WASTE CONTAINER ASSEMBLY - A container for disposing of waste includes a receptacle and a first pivoting member functionally associated with the receptacle. The first pivoting member includes a first disposal surface. A second pivoting member functionally associated with the receptacle includes a second disposal surface. The second pivoting member is operatively coupled to the first pivoting member such that waste deposited on either the first disposal surface or the second disposal surface causes concurrent counter rotation of both the first pivoting member and the second pivoting member to dispose of the waste into the receptacle. | 02-28-2013 |
20150034665 | WASTE CONTAINER ASSEMBLY - A container for disposing of waste includes a receptacle, a first pivoting member having a first disposal surface and a first pair of opposing sides, and a second pivoting member having a second disposal surface and a second pair of opposing sides. The second pair of opposing sides are operatively coupled to the first pair of opposing sides such that waste deposited on either the first disposal surface or the second disposal surface causes concurrent counter rotation of both the first pivoting member and the second pivoting member. The first pivoting member includes a pair of opposing projections secured in a stationary position to the first pair of opposing sides and the second pivoting member includes a pair of opposing apertures formed in a stationary position in the second pair of opposing sides. The opposing projections translate within the opposing apertures during the concurrent counter rotation. | 02-05-2015 |
David Goldstein, Durham, NC US
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20100297080 | GENETIC MARKERS ASSOCIATED WITH INTERFERON-ALPHA RESPONSE - The present invention provides genetic markers on human chromosome 19 that are associated with a beneficial response to interferon alpha (IFN-α). These IFN-α response markers arc useful, inter alia, to identify patients who are most likely to benefit from treatment with IFN-α pharmaceutical compositions and drug products, in methods of treating patients having a disease susceptible to treatment with an IFN-α, and in methods for selecting the most appropriate therapy for such patients. | 11-25-2010 |
David Goldstein, Chester, VA US
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20090039102 | BEAD FEEDER - A bead feeder for serially delivering beads to a downstream location comprises a bead supply wheel which rotates about a vertical axis. The bead supply wheel includes a bead supply bowl and a plurality of radially arranged channels below the bowl connected to rotate with the bowl. Discharge openings in the bowl are in alignment with the radially arranged channels to delivery beads to those channels, and a bead receiving pocket is positioned at the outer end of each channel. A transfer wheel picks up beads from the bead receiving pockets and transfers those beads to a delivery wheel by vacuum transfer and release. The delivery wheel serially delivers the beads to the downstream location. | 02-12-2009 |
David B. Goldstein, Durham, NC US
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20120282224 | MARKERS ASSOCIATED WITH RIBAVIRIN-INDUCED ANEMIA - The present invention provides genetic markers and biomarkers that are associated with anemia induced by ribavirin therapy. The genetic markers are located in the ITPA gene and elsewhere on human chromosome 20 and the biomarkers are low ITPA activity phenotypes. These markers of ribavirin-induced anemia are useful, inter alia, to identify patients who are least likely to develop anemia upon treatment with ribavirin pharmaceutical compositions and drug products, in methods of treating patients having a disease susceptible to treatment with ribavirin, and in methods for selecting the most appropriate therapy for such patients. | 11-08-2012 |
20130251677 | GENETIC MARKERS ASSOCIATED WITH INTERFERON-ALPHA RESPONSE - The present invention provides genetic markers on human chromosome 19 that are associated with a beneficial response to interferon alpha (IFN-α). These IFN-α response markers are useful, inter alia, to identify patients who are most likely to benefit from treatment with IFN-α pharmaceutical compositions and drug products, in methods of treating patients having a disease susceptible to treatment with an IFN-α, and in methods for selecting the most appropriate therapy for such patients. | 09-26-2013 |
David H. Goldstein, Boulder, CO US
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20080208679 | SYSTEM AND PROGRAM PRODUCT FOR SELECTING A SUPPLIER - Under the present invention, componentized costs for providing/producing an item are collected from a plurality of suppliers. The componentized costs include the fixed and variable costs associated with raw materials and production for providing the item according to various specifications and order quantities. When a buyer wishes to obtain the item, a particular order specification and a demand forecast for the item will be provided. Based on the particular specification, the demand forecast and the componentized costs, an optimal order quantity for the item will be calculated. Then, a total (lifetime) cost for providing the item will be calculated for each supplier. The supplier having the lowest total cost for the projected lifetime of the item will be identified to the buyer. | 08-28-2008 |
Douglas S. Goldstein, Waikoloa, HI US
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20130012234 | Systems and Methods for Position Tracking and Reporting of Objects - Geographic location and environmental conditions of a tracking target are reported by a position tracking and reporting (“PTR”) device. Reports are aggregated and stored by a server system, which also provides access to the information for interactive and automatic programmatic use. A mobile phone (smartphone) interface allows system conditions to be examined, and PTR device operating envelope to be modified. | 01-10-2013 |
Eliot Goldstein, Fairfax, VA US
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20090308582 | Heat Exchanger - A heat exchanger and a method for fabricating the heat exchanger are disclosed. The heat exchanger comprises a heat exchanger core that is formed from a plurality of stacked aluminum panels that are joined together via friction stir welding. Each panel in the core is formed from at least two aluminum extrusions that are joined to one another via friction stir welding. | 12-17-2009 |
Elizabeth Goldstein, Carlisle, PA US
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20090018987 | Computational Intelligence System - A method of computational intelligence is disclosed. | 01-15-2009 |
Eric J. Goldstein, Tucson, AZ US
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20110239364 | Portable Commode, Shower and Bath Wheelchair Apparatus - A portable commode, shower, and bath wheelchair apparatus comprising a first support frame, a second support frame, a mechanical interface interconnecting the first support frame to the second support frame thereby forming a first contiguous support member and a second contiguous support member. A seat assembly is slidingly attached to both the first contiguous support member and to the second contiguous support member. | 10-06-2011 |
James Goldstein, Bloomfield Hills, MI US
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20110248193 | METHOD AND APPARATUS FOR SHIELDING MEDICAL PERSONNEL FROM RADIATION - Systems and methods for shielding medical personnel from radiation are provided. A radiation-shielding barrier is positioned between the medical personnel and the radiation source. The radiation-shielding barrier includes an opening such that a portion of the table extends through the opening in the barrier. Medical personnel are protected from secondary radiation transmitted through the patient via a special layering technique of a first, flexible sterile drape, a flexible radiation-resistive drape, and a second flexible sterile drape. The system includes an upper shield and a lower shield of independent movement and a linking mechanism between the two, while maintaining the radiation seal. The system also includes a mechanism for maintaining the radiation barrier between the upper shield and the patient aperture hoop, preventing a radiation gap from forming between the flexible portions of the system (e.g. flexible drapes, curtains, etc.) and the non-flexible portions of the system (e.g. upper shield, lower shield, radiopaque transparent window, etc.). | 10-13-2011 |
James A. Goldstein, Bloomfield Hill, MI US
Jason Goldstein, Decatur, GA US
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20080300206 | Alpha-Synuclein Kinase - The invention provides agents and methods for treatment of diseases associated with Lewy body diseases (LBDs) in the brain of a patient. Preferred agents include inhibitors of PLK2 kinase. | 12-04-2008 |
20110207796 | ALPHA-SYNUCLEIN KINASE - Agents and methods for treatment of diseases associated with Lewy body diseases (LBDs) in the brain of a patient are provided. Preferred agents include inhibitors of PLK2 kinase. | 08-25-2011 |
Jason Goldstein, Salem, NH US
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20110022324 | MOLECULAR READER - Systems and methods disclosed include: a support apparatus configured to detachably receive a chip; movable pins extendible from a first position to a second position, where, in the first position, the movable pins do not contact a chip positioned on the support apparatus, and in the second position, the movable pins contact electrical terminals of a heating element within a chip positioned on the support apparatus; a radiation source configured to direct radiation to be incident on a chip positioned on the support apparatus; a detector; and an electronic processor, the electronic processor being configured to detect molecules in a sample positioned within the chip, and to determine a temperature of the chip by measuring an electrical resistance between two of the multiple pins connected to the electrical terminals. | 01-27-2011 |
Jay Scott Goldstein, Centerville, VA US
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20100046848 | Compression For Holographic Data and Imagery - Image pixel intensity data is transformed to a holographic representation of the image. A subset of the holographic representation is modeled. Model parameters constitute a compressed image representation. A two-dimensional Fourier transform can be applied to obtain the holographic image. Modeling includes applying an analysis portion of an adaptive analysis/synthesis prediction methodology to a subset of the holographic representation. Linear prediction can be the adaptive analysis/synthesis prediction methodology. Prior to modeling, one-dimensional Fourier transform can be performed on the holographic representation and the linear prediction is one-dimensional. Model parameters are preferably quantized. Embodiments include determining error between the model and the model's input data. There the compressed image representation the error, which also can be quantized. The subset of the holographic representation can be less than all the representation. The subset can be a plurality of complete rows; preferably substantially symmetric about 0 Hz. | 02-25-2010 |
Jeffrey Goldstein, Wilmington, DE US
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20090093461 | Methods of Treating Anxiety and Mood Disorders - Methods of treating at least one symptom or condition associated with Anxiety Disorders and/or Mood Disorders comprising administering an effective amount of a compound of Formula I | 04-09-2009 |
Jeffrey M. Goldstein, Wilminton, DE US
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20110136785 | METHOD OF TREATMENT - A method of treating at least one symptom or condition associated with but not limited to: 1) Substance-Related Disorders including but not limited to Substance Dependence, Substance Abuse, Substance Intoxication, Substance Withdrawal, Alcohol-Related Disorders, Amphetamine (or Amphetamine-Like)-Related Disorders, Caffeine-Related Disorders, Cannabis-Related Disorders, Cocaine-Related Disorders, Hallucinogen-Related Disorders, Inhalant-Related Disorders, Nicotine-Related Disorders, Opioid-Related Disorders, Phencyclidine (or Phencyclidine-Like)-Related Disorders, and Sedative-, Hypnotic- or Anxiolytic-Related Disorders. 2) Attention-Deficit and Disruptive Behavior Disorders. 3) Eating Disorders. 4) Personality Disorders including but not limited to Obsessive-Compulsive Personality Disorder. 5) Impulse-Control Disorders, comprising administering an effective amount of Formula I | 06-09-2011 |
Jeffrey M. Goldstein, Wilmington, DE US
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20090093460 | Compositions - Pharmaceutical compositions, oral pharmaceutical compositions, and solid dosage forms comprising up to about 750 mg of 11-piperazin-1-yldibenzo[b,f] [1,4]thiazepine, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier or diluent are provided. | 04-09-2009 |
20110136784 | Method of Treating Anxiety Disorders - A method of treating at least one symptom or condition associated with but not limited to: Anxiety Disorders including but not limited to Panic Disorder Without Agoraphobia, Panic Disorder With Agoraphobia, Agoraphobia Without History of Panic Disorder, Specific Phobia, Social Phobia, Obsessive-Compulsive Disorder, Postaumatic Stress Disorder, Acute Stress Disorder, Generalized Anxiety Disorder and Generalized Anxiety Disorder Due to a General Medical Condition comprising administering an effective amount of Formula I | 06-09-2011 |
20110136786 | METHOD OF TREATING MOOD DISORDERS - Methods of treating mood disorders comprising administering an effective amount of 11-piperazin-1-yldibenzo[b,f][1,4]thiazepine or a pharmaceutically acceptable salt thereof and pharmaceutical compositions therefor. | 06-09-2011 |
20110144088 | METHOD OF TREATING SLEEP DISORDERS - A method of treating at least one symptom or condition associated with but not limited to: Sleep Disorders including but not limited to 1) Dyssomnia Disorders including but not limited to: a) Primary inomnia, b) Primary Hypersomnia, and c) narcolepsy; and 2) Parasomnias Disorders including but not limited to a) Nightmare Disorder, Sleep Terror Disorder and Sleepwalking Disorder, comprising administering an effective amount of Formula I | 06-16-2011 |
20110144089 | METHOD OF TREATING SCHIZOPHRENIA AND OTHER DISORDERS - A method of treating at least one symptom or condition associated with but not limited to: 1) Schizophrenia and other Psychotic Disorders including but not limited to Psychotic Disorder, Schizophreniform Disorder, Schizoaffective Disorder, Delusional Disorder, Brief Psychotic Disorder, Shared Psychotic Disorder, and Psychotic Disorder Due to a General Medical Condition and 2) Dementia and other Cognitive Disorders comprising administering an effective amount of Formula I | 06-16-2011 |
Jonathan D. Goldstein, Kirkland, WA US
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20090125550 | TEMPORAL EVENT STREAM MODEL - Disclosed is a temporal stream model that provides support both for query language semantics and consistency guarantees, simultaneously. A data stream is modeled as a time varying relation. The data stream model incorporates a temporal data perspective, and defines a clear separation in different notions of time in streaming applications. The temporal stream model further refines the conventional application time into two temporal dimensions of valid time and occurrence time, and utilizes system time (the clock of the stream processor) for modeling out-of-order event delivery but thereby providing three temporal dimensions. The methods for assigning timestamps and quantifying latency form the basis for defining a spectrum of consistency levels. Based on the selected consistency level, an output can be produced. The utilization of system time facilitates the retraction of incorrect output and the insertion of the correct revised output. | 05-14-2009 |
20090125635 | CONSISTENCY SENSITIVE STREAMING OPERATORS - A new approach for handling stream imperfections based on speculative execution involves the retraction of incorrect events facilitated using operators to remove speculatively produced incorrect output. Additionally, parameters are disclosed that define a spectrum of consistency levels. A first parameter, maximum blocking time, exposes a tradeoff between a degree of speculation and latency. A second parameter, the maximum time data is remembered before being purged from the system, exposes a tradeoff between state size and correctness. Varying these two parameters produces a spectrum of consistency levels (e.g., strong, middle, weak) which address the specific tradeoffs built into other systems. Retraction is accomplished using operators that include Select, AlterLifetime, Join, Sum, Align, and Finalize. | 05-14-2009 |
20090319687 | STREAMING OPERATOR PLACEMENT FOR DISTRIBUTED STREAM PROCESSING - A streaming operator assignment system and method for determining a streaming operator assignment that minimizes overload in a data processing system. Embodiments of the streaming operator assignment system include an optimization goals definition module, which defines optimization goals in terms of fundamental quantities that system administrators and application writers want to control, such as minimizing the worst case latency over all periods of time, or minimizing how much the system is backlogged with work. Embodiments of the streaming operator assignment system also include an optimization goals solution module that optimizes and solves a selected optimization goal. A specialized optimization technique is used to find the best operator (or load) assignment using the optimization goals to measure of the value of the assignment. This technique minimizes an optimization goal by iterating over all possible operators assignments over all possible nodes to find the operator assignment that minimizes the desired optimization goal. | 12-24-2009 |
20100088325 | Streaming Queries - The described implementations relate to recursive streaming queries. One technique processes a recursive streaming query through a query graph. The technique also detects when output produced by executing the query graph advances to a specific point. | 04-08-2010 |
20110282812 | DYNAMIC PATTERN MATCHING OVER ORDERED AND DISORDERED DATA STREAMS - Architecture introduces a new pattern operator referred to as called an augmented transition network (ATN), which is a streaming adaptation of non-reentrant, fixed-state ATNs for dynamic patterns. Additional user-defined information is associated with automaton states and is accessible to transitions during execution. ATNs are created that directly model complex pattern continuous queries with arbitrary cycles in a transition graph. The architecture can express the desire to ignore some events during pattern detection, and can also detect the absence of data as part of a pattern. The architecture facilitates efficient support for negation, ignorable events, and state cleanup based on predicate punctuations. | 11-17-2011 |
20110283295 | EXTENSIBILITY MODEL FOR STREAM-BASED OPERATORS AND AGGREGATES - An extensibility framework that allows a user to write user-defined modules that include user-defined operators (UDO) and user-defined aggregators (UDA) in a non-temporal fashion without the need to worry about temporal attributes of events (or event types). The temporal domain is managed on behalf of the user, and allows the user to write operators and aggregates in the temporal data streaming domain as well as to port existing libraries of non-temporal UDOs/UDAs to the temporal data streaming domain. Temporal attributes and event types are managed for non-temporal UDOs/UDAs by the extensibility framework on behalf of the UDO/UDA writer. Windows can be employed to bridge the gap between the non-temporal domains and temporal domains. Support for complex event processing (CEP) is provided in UDOs/UDAs for base classes related to a CEP operator, CEP aggregate, CEP time sensitive operator, and CEP time sensitive aggregate. | 11-17-2011 |
20120084322 | RECURSIVE PROCESSING IN STREAMING QUERIES - The described implementations relate to recursive streaming queries. One technique processes a recursive streaming query through a query graph. The technique also detects when output produced by executing the query graph advances to a specific point. | 04-05-2012 |
20140250151 | DYNAMIC PATTERN MATCHING OVER ORDERED AND DISORDERED DATA STREAMS - Architecture introduces a new pattern operator referred to as called an augmented transition network (ATN), which is a streaming adaptation of non-reentrant, fixed-state ATNs for dynamic patterns. Additional user-defined information is associated with automaton states and is accessible to transitions during execution. ATNs are created that directly model complex pattern continuous queries with arbitrary cycles in a transition graph. The architecture can express the desire to ignore some events during pattern detection, and can also detect the absence of data as part of a pattern. The architecture facilitates efficient support for negation, ignorable events, and state cleanup based on predicate punctuations. | 09-04-2014 |
Jonathan D. Goldstein, Woodinville, WA US
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20120304003 | OPERATOR STATE CHECKPOINTS - A checkpoint marker can be received at a first operator. The first operator can process the checkpoint marker by sending the checkpoint marker to a second operator and sending state checkpoint information representing a state of the first operator to a checkpoint writer. The checkpoint information can be used to rehydrate the state of one or more operators. For example, after a system failure, system shutdown, etc., checkpoint information can be received from a reader unit at a checkpoint information input queue of the first operator. A state of the first operator can be rehydrated using the checkpoint information. Processing of information in a data input queue of the first operator can be suspended while the checkpoint information is used to rehydrate the state of the first operator. Other operators in a system with the first operator (e.g., the second operator) may be checkpointed and rehydrated in the same manner as the first operator. | 11-29-2012 |
20120324453 | EFFICIENT LOGICAL MERGING OVER PHYSICALLY DIVERGENT STREAMS - A logical merge module is described herein for producing an output stream which is logically compatible with two or more physically divergent input streams. Representative applications of the logical merge module are also set forth herein. | 12-20-2012 |
Jonathan David Goldstein, Kirkland, WA US
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20090319501 | TRANSLATION OF STREAMING QUERIES INTO SQL QUERIES - A query translation system and method for processing a streaming language query on existing or stored data. The streaming language query is applied against a data stream log by first translating the streaming language query into a database management system query (such as a SQL query) and then applying the translated streaming language query against the data stream log. Embodiments of the query translation system and method include a bitemporal converter that converts a bitemporal data stream log into a canonical history table format. Once in this format, embodiments of the query translation system and method translate a streaming language query into a SQL query. A categorization of each of the streaming operators that make up the streaming language query is performed to determine which translation technique to use. In general, one of three general translation techniques is used based on these categorizations of the streaming operators. | 12-24-2009 |
20110320586 | Flexible and Safe Monitoring of Computers - Described is a server monitoring technology that is scalable to large numbers of servers, e.g., in a datacenter. Agents on servers run queries to monitor data sources for that server, such as performance counters and other events. The agents monitor their resource usage and those of monitored events to stay within an administrator-specified resource budget (policy), e.g., by modifying the running queries and/or monitoring parameters. A controller receives results of the monitoring, analyzes the results, and takes action as needed with respect to server operation and monitoring. The controller may dynamically update an agent's queries, monitoring parameters and/or monitored data post-processing operations. The controller may issue alerts and reports, including alerts indicative of inter-server problems between two or more servers. | 12-29-2011 |
20120166417 | ASYNCHRONOUS TRANSFER OF STATE INFORMATION BETWEEN CONTINUOUS QUERY PLANS - Described herein are technologies pertaining to migrating state information of operators in a first continuous query plan to a second continuous query plan in an asynchronous manner, such that the first continuous query plan need not cease executing during the migrating of the state information. State information pertaining to stateful operators, such as join operators, is migrated from the first continuous query plan to the second continuous query plan by way of a transformation plan. State matching is utilized to generate the transformation plan. | 06-28-2012 |
Jonathan David Goldstein, Woodinville, WA US
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20120297080 | Stream Operator - Aspects of the subject matter described herein relate to stream operators. In aspects, a stream event is received. Based on a timestamp associated with the stream event and the number of stream operators that have asked to be activated prior to or at the timestamp, zero or more stream objects are informed of one or more time events and torn down if no longer needed. In addition, a destination stream operator is instantiated, if needed, data (e.g., the timestamp and packet, if any) corresponding to the stream event is provided to a stream operator, output data, if any, is received from the stream operator, and the stream operator is torn down if it no longer needs state data between invocations. | 11-22-2012 |
20140337362 | MERGING OF SORTED LISTS USING ARRAY PAIR - The formulation of a merged sorted list from multiple input sorted lists in multiple phases using an array pair. Initially, the first array is contiguously populated with the input sorted lists. In the first phase, the first and second input sorted lists are merged into a first intermediary merged list within the second array. Each subsequent phase merges a prior intermediary merged list resulting from the prior phase and, a next input sorted list in the first array to generate a next intermediary merged list, or a merged sorted list if there or no further input in the first array. The intermediary merged lists alternate between the first array and the second array from one phase to the next phase. | 11-13-2014 |
Joshua Goldstein, Radnor, PA US
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20090175784 | Anti-Alpha V Immunoliposome Composition, Methods, and Uses - An immunoliposome composition targeted to the alphaV-integrin subunit of integrin receptors comprised of ligand-targeted liposomes bearing at least one targeting-ligand derived from an antibody and having binding specificity for at least one integrin receptor comprising an alpha V subunit including αvβ1, αvβ3 αvβ5, αvβ6, or αvβ8 integrin cell receptors is described. The antibody-derived targeting ligand may be a Fab′ fragment, a scFv, or the like. Binding of the immunoliposome to αv-integrin expressing cells, preferably results in internalization of the immunoliposome for cytoplasmic delivery of a liposome-entrapped agent. | 07-09-2009 |
20110268655 | ANTI-ALPHA V IMMUNOLIPOSOME COMPOSITIONS, METHODS AND USES - An immunoliposome composition targeted to the alphaV-integrin subunit of integrin receptors comprised of ligand-targeted liposomes bearing at least one targeting-ligand derived from an antibody and having binding specificity for at least one integrin receptor comprising an alpha V subunit including αvβ1, αvβ3 αvβ5, αvβ6, or αvβ8 integrin cell receptors is described. The antibody-derived targeting ligand may be a Fab′ fragment, a scFv, or the like. Binding of the immunoliposome to αv-integrin expressing cells, preferably results in internalization of the immunoliposome for cytoplasmic delivery of a liposome-entrapped agent. | 11-03-2011 |
Joshua Goldstein, Malvern, PA US
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20090171072 | Process for Preparing Unaggregated Antibody FC Domains - Methods useful for producing a solution of purified Fc peptide chains are disclosed. The methods employ protein A chromatography to separate high molecular weight, aggregated peptide chains comprising antibody Fc domains from lower molecular weight unaggregated peptide chains that also comprise antibody Fc domains. The solutions of purified Fc peptide chains obtained by the methods of the invention contain less than 5% aggregate and greater than 70% of the Fc peptide chains subjected to purification. | 07-02-2009 |
Kathryn Marlene Goldstein, Chicago, IL US
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20120211134 | Handbag with Removable Liner - A handbag includes a containment structure with a pair of opposed sidewalls, and a pair of opposed end walls. Each end wall is adjacent the pair of sidewalls and a lower wall interconnects the sidewalls and the end walls. The lower wall includes an upper inner surface. A liner is removably secured to the upper inner surface of the lower wall. The liner has a length and width to substantially cover the upper inner surface of the lower wall. A method of applying the liner is also provided. | 08-23-2012 |
Larry J. Goldstein, Doylestown, PA US
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20100063395 | Telemedicine platform for standardized interpretation of vascular data using vascular analysis - A system and method, for obtaining and analyzing vascular data and generating results, that uses vascular test data to determine the state of the vessel. The data and the determinations can be used to generate reports, render diagnoses or identifying ailments, and may do so remotely. The system includes a telemedicine server and may include a number of other modules such as work stations, review tools, data storage modules, etc. The invention allows rapid and efficient analysis of the data, and provides mechanisms for comparing patient data to know or measured normative data sets, remotely if desired, and provides more accurate and less invasive diagnoses based on vascular conditions. The invention permits remote receipt, processing and distribution of the data and diagnoses. | 03-11-2010 |
Leonard Goldstein, Shoreview, MN US
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20090000090 | METHOD FOR INSULATIVE FILM FOR CAPACITOR COMPONENTS - The present subject matter includes an apparatus including a capacitor stack, including at least one substantially planar anode layer arranged in stacked alignment adjacent at least one substantially planar cathode layer, with at least one separator layer disposed therebetween. In this embodiment, the present subject matter includes at least one conformed film at least partially enveloping the capacitor stack in a bound state and adapted to electrically isolate the capacitor stack. | 01-01-2009 |
Leonard I. Goldstein, Shoreview, MN US
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20110094093 | METHOD AND APPARATUS FOR A SELF-ALIGNING POWER SOURCE CASING - By way of example, the present subject matter provides a method, including stacking a plurality of substantially planar electrodes into a stack, in alignment, encapsulating the stack by pressing a first beveled edge of a first cup-shaped housing piece against a second beveled edge of a second cup-shaped housing piece, with the first beveled edge of the first cup-shaped housing piece encouraged into substantially coextensive alignment with the second beveled edge of the second cup-shaped housing piece and joining the first beveled edge of the first cup-shaped housing piece to the second beveled edge of the second cup-shaped housing piece. | 04-28-2011 |
Mark Goldstein, Chantilly, VA US
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20090293018 | HISTORY-BASED TRACKING OF USER PREFERENCE SETTINGS - A process is disclosed for using the existing Universal Resource Identifier (URI) history feature of browsers to maintain user preference settings, or other state information, used by one or more web sites or other systems. In one embodiment, when a user makes a particular preference selection on a web site, the user's selection is recorded in the browser's URI history by causing the browser to access a URI (or a set of URIs) representing the particular selection. The same or a different web site may subsequently test the browser's URI history for this particular URI by including appropriate JavaScript or other executable code in a page requested by the browser. Depending upon the outcome of this test, the web site and/or the page's executable code may take an appropriate action or inaction consistent with the preference selection. | 11-26-2009 |
Mark H. Goldstein, Chantilly, VA US
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20140337376 | HISTORY-BASED TRACKING OF USER PREFERENCE SETTINGS - A process is disclosed for using the existing Universal Resource Identifier (URI) history feature of browsers to maintain user preference settings, or other state information, used by one or more web sites or other systems. In one embodiment, when a user makes a particular preference selection on a web site, the user's selection is recorded in the browser's URI history by causing the browser to access a URI (or a set of URIs) representing the particular selection. The same or a different web site may subsequently test the browser's URI history for this particular URI by including appropriate JavaScript or other executable code in a page requested by the browser. Depending upon the outcome of this test, the web site and/or the page's executable code may take an appropriate action or inaction consistent with the preference selection. | 11-13-2014 |
Michael Goldstein, Ridgefield, CT US
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20130060537 | METHOD OF MODELING FOR DRUG DESIGN, EVALUATION AND PRESCRIPTION IN THE TREATMENT OF DISEASE - A method implemented on at least one specifically programmed computer to improve the outcome of a drug trial. The method includes (a) generating a parameterized mathematical model of disease and immune response, (b) including in the parameterized mathematical model effects from one or more drugs with time-dependent variables that can change during a therapy, (c) creating a calibrated model using empirical data to aid in determining parameters of the parameterized mathematical model, (d) determining responses of the calibrated model to a series of time-dependent drug therapies, and (e) selecting at least one therapy based on the determined responses of the model. | 03-07-2013 |
Michael Louis Goldstein, Denver, CO US
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20090119693 | APPARATUS, SYSTEM AND METHOD FOR DELIVERING POLLING AND USER GENERATED CONTENT TO DISPARATE COMMUNICATION - Various embodiments of apparatus, systems and/or methods are described for providing user generated content relating to a subject, and collecting polling data relating to the subject, on multiple disparate communication devices. User generated content is received from one or more disparate communication devices and provided for presentation on at least one of the communication devices. Polling data is also received from at least one of the end-users of the communication devices viewing the user generated content, and tabulated to generate poll results displayable on the communication devices. | 05-07-2009 |
20090169178 | APPARATUS, SYSTEM AND METHOD FOR STORING AND PRESENTING TO A USER DIFFERENT TYPES OF CONTENT REGARDING A SUBJECT - Various embodiments of apparatus, systems and/or methods are described for presenting different types of content regarding a subject to a user. The different types of content may include user generated content, media content, advertisements, polls and poll results. The content may also include candidate content if the subject is an election. The different types of content may be transmitted to a digital video recorder (DVR) and saved for subsequent presentation to a user. A user may participate in a poll, and the user's responses to the poll may be utilized to determine which portions of the content are presented to the user. | 07-02-2009 |
Norman Goldstein, Ellicott City, MD US
Peter Goldstein, Providence, RI US
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20090099786 | BIOPOLYMER SEQUENCING BY HYBRIDIZATION OF PROBES TO FORM TERNARY COMPLEXES AND VARIABLE RANGE ALIGNMENT - Methods for sequencing a biopolymer by forming local ternary complexes along the length of the double-stranded biopolymer target molecule using one or more probes and obtaining information about the location of the probe(s) using a detector. These methods offer particular advantage when implemented with nanopore (including micropore) detection systems. | 04-16-2009 |
20100261285 | TAGGED-FRAGMENT MAP ASSEMBLY - A method for determining a sequence of a biomolecule, the method including binding a plurality of uniform probes to a biomolecule fragment, creating a collection of binding signatures for the fragment with each binding signature representing a series of distances between binding sites within the fragment, and grouping the binding signatures into a plurality of signature clusters based at least in part on distances between the binding sites in each binding signature. For each binding signature in a first cluster, a potential successor binding signature is selected from signature clusters other than the first signature cluster, and one of the potential successor binding signatures is identified as a successor binding signature. The last two steps are repeated until the successor signature represents a terminal signature, resulting in a sequence of signatures representing at least a portion of the biomolecule. | 10-14-2010 |
20130011934 | BIOPOLYMER SEQUENCING BY HYBRIDIZATION OF PROBES TO FORM TERNARY COMPLEXES AND VARIABLE RANGE ALIGNMENT - Methods for sequencing a biopolymer by forming local ternary complexes along the length of the double-stranded biopolymer target molecule using one or more probes and obtaining information about the location of the probe(s) using a detector. These methods offer particular advantage when implemented with nanopore (including micropore) detection systems. | 01-10-2013 |
Rachel A. Goldstein, Chicago, IL US
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20110092773 | VIDEO LARYNGOSCOPE PROVIDING SUCTION - A video laryngoscope is provided that includes a body having a handle portion and a blade portion. The blade portion terminates in a tip and defines at least one aperture formed proximal to the tip. The blade portion is dimensioned for oral insertion into a subject buccal cavity. A fiber optic light source terminates within the blade portion and upon light source activation illuminates an area including the tip. A video system is coupled to the body and relays imagery of the tip and surrounding area to a video monitor. A channel extending through the body provides fluid communication to the aperture and an external source of suction. As a result, an operator is capable of visualizing debris and/or obstructions in a subject airway and is able to observe and guide the scope for suction removal. | 04-21-2011 |
Robert C. Goldstein, Grand Blanc, MI US
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20090145894 | Passive inductor for improved control in localized heating of thin bodies - The present invention is a magnetic flux controlling device in the form of a passive inductor which improves heat pattern control for induction heating of objects such as thin, flat bodies. The device comprises a magnetic core and at least one electrical conductor that together do not form a closed electrical loop. The device is located on the opposite side of the object to be heated from the induction coil and may be adjusted along the axis of the induction coil to manipulate the heat pattern in different zones of the part. | 06-11-2009 |
Robert S. Goldstein, Bridgeport, CT US
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20080243553 | Methods and systems for providing a nutraceutical program specific to an individual animal - The present invention relates to methods and systems for providing an animal with a nutraceutical program that is specifically tailored to address the deficiencies and/or needs of the particular animal. Blood is drawn from the animal and analyzed at a lab to obtain blood test results. The blood test results are scored to obtain at least one blood test score for at least one corresponding blood parameter. If the at least one blood test score falls within a normal range but outside of an optimal range, one or more nutraceuticals needed to bring the animal within the optimal range for the at least one corresponding blood parameter are identified. A prescribed dosage amount is then calculated for at least one of the one or more identified nutraceuticals for the animal. The calculation of the prescribed dosage amount is based on at least the blood test score for the corresponding blood parameter and a deviation of the blood test score from the optimal range. | 10-02-2008 |
20090130702 | Methods and systems for providing a nutraceutical program specific to an individual animal - The present invention relates to methods and systems for providing an animal with a nutraceutical program that is specifically tailored to address the deficiencies and/or needs of the particular animal. Blood is drawn from the animal and analyzed at a lab to obtain blood test results. The blood test results are scored to obtain at least one blood test score for at least one corresponding blood parameter. If the at least one blood test score falls within a normal range but outside of an optimal range, one or more nutraceuticals needed to bring the animal within the optimal range for the at least one corresponding blood parameter are identified. A prescribed dosage amount is then calculated for at least one of the one or more identified nutraceuticals for the animal. The calculation of the prescribed dosage amount is based on at least the blood test score for the corresponding blood parameter and a deviation of the blood test score from the optimal range. | 05-21-2009 |
Robert Turk Goldstein, Crownsville, MD US
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20120300579 | DIRECT FIELD ACOUSTIC TESTING SYSTEM AND METHOD - A direct field acoustic testing system includes at least one control microphone, a controller operatively coupled to the control microphone such that the controller receives at least one input signal from the control microphone, and at least four acoustic transducers operatively coupled to the controller such that each transducer is separately controllable by the controller such that a separate output signal is received by each transducer from the controller. A setup is applied to each of the acoustical transducers. The acoustic output of each of the acoustical transducers is monitored using the at least one control microphone. The output signal of each control microphone with respect to each acoustical transducer is compared to a reference spectrum to create a matrix of error functions, and a corrected drive signal computed for each acoustical transducer is applied to the respective acoustical transducer. | 11-29-2012 |
20120300580 | DIRECT FIELD ACOUSTIC TESTING SYSTEM, CONTROLS, AND METHOD - A direct field acoustic testing system includes at least one control microphone, a controller operatively coupled to the control microphone such that the controller receives at least one input signal from the control microphone, and at least four acoustic transducer groups operatively coupled to the controller such that each transducer is separately controllable by the controller such that a separate output signal is received by each transducer from the controller. A setup signal is applied to each of the acoustical transducers. The acoustic output of each of the acoustical transducers is monitored using the at least one control microphone. Assumptions regarding the relationship between the acoustic fields measured by the control microphones are made to enable the controller to reduce the number of calculations needed to compute error functions and corrected drive signals to be applied to the acoustic transducer groups. | 11-29-2012 |
Robin L. Goldstein, Bellevue, WA US
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20090300658 | DEFINING, DISTRIBUTING AND PRESENTING DEVICE EXPERIENCES - Platforms and techniques for defining, authorizing/authenticating, distributing, and presenting dynamic device experiences using a number of hierarchically-related, declarative language data structures, such as extensible markup language (“XML”) elements or attributes. A dynamic device experience is presented when two electronic devices are in communication via a communication medium. The data structures are processed to present a graphical user interface to a user—the graphical user interface implements a dynamic device experience associated with the other electronic device. In one exemplary scenario, independent hardware vendors (“IHVs”) author XML documents that include device experience information (such as branding or advertising information, access to Web services or applications, and access to device functionality), in the form of items of data stored in the data structures. The XML documents are verified against a predetermined schema, secured using a cryptographic technique such as a digital signature, and discovered/distributed in flexible, tamper-resistant manners. | 12-03-2009 |
Samuel Goldstein, Merion, PA US
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20090199700 | Knob for Adjusting a Rotatable Control on an Instrument Pedal - A knob for adjusting a rotatable control on a foot operated musical instrument effects pedal is disclosed. The knob has a shaft having a first end, a second end, and an outer perimeter bounding a first cross-sectional area, the first end being securable to the rotatable control. The knob also has a wheel located at the second end of the shaft, the wheel having an outer perimeter bounding a second cross-sectional area which is greater than the first cross-sectional area, a bottom surface rigidly attached to the second end of the shaft, and a top surface located opposite the bottom surface, wherein at least a portion of the top surface has a frictional surface adapted to receive a user's foot for rotating the knob and thereby adjusting the rotatable control. | 08-13-2009 |
Seth Goldstein, Exeter, NH US
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20110306396 | Dance Game and Tutuorial - Presented herein are methods, apparatuses, programs, and systems for scoring a player performance comprising one or more poses in a dance-based video game. a performance 3D skeleton is received that indicates a pose of the player. A score is calculated by comparing a position, a timing, or both, associated with one or more joints of the performance 3D skeleton to a position, a timing, or both, associated with one or more joints of a target pose and altering one or more characteristics of the dance-based video game based on the score. | 12-15-2011 |
Seth David Goldstein, Exeter, NH US
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20100174734 | ASYNCHRONOUS DATABASE UPDATES BETWEEN COLLABORATIVE APPLICATIONS AND SEARCH UTILITIES - Tools and techniques for asynchronous database updates between client applications and search utilities are provided. These tools may receive indications of updates occurring within a workspace in which two or more users are collaborating. Updates to the collaborative workspace may be committed to a collaboration database maintained internally by a collaboration application. The tools may generate request to commit these updates to a search utility, so that the updates are searchable. The search utility maintains a search database that is decoupled from and operates independently of the collaboration database. The tools may increment a notification counter associated with the collaborative workspace, with the notification counter tracking how many requests to commit updates are pending. Finally, the tools may send the request to commit the update to the search database asynchronously with respect to the collaboration database. | 07-08-2010 |
Steven Goldstein, Atlanta, GA US
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20100285587 | Tissue Graft - A method of preparing a tissue graft material is disclosed. The disclosure also relates to a multipurpose tissue graft material and to methods of using same as a replacement for vascular and non-vascular tissue. | 11-11-2010 |
20120009644 | Tissue Implants for Implantation and Methods for Preparing the Same - A method is provided for preparing a tissue implant for implantation. The method includes harvesting a tissue material from a human or an animal donor, treating the tissue material with water or a hypotonic solution to lyse native cells of the tissue material, treating the tissue material in a nuclease-containing solution which includes an antimicrobial, treating the tissue material with an alkaline alcohol solution, treating the tissue material with a chlorine dioxide treatment solution, and sterilizing the tissue material. | 01-12-2012 |
20120010725 | Tissue Implants for Implantation and Methods for Preparing the Same - A method is provided for preparing a tissue implant for implantation. The method includes treating a pericardium tissue material, which has been harvested from a donor and rendered essentially acellular, with a chlorine dioxide treatment solution; and thereafter treating the pericardium tissue material with an antioxidant solution, which comprises ascorbic acid or a salt thereof. | 01-12-2012 |
20140271904 | METHODS FOR PREPARING TISSUE IMPLANTS - A method is provided for preparing a biological tissue for implantation. The method includes providing a biological tissue from a human or animal donor, treating the biological tissue with an antiviral treatment formulation, lysing the biological tissue, decellularizing the biological tissue with a decellularization treatment formulation, and decontaminating the biological tissue with an alkaline alcohol solution. The antiviral treatment formulation may include a solution of peracetic acid and an alcohol, wherein the peracetic acid is present in the antiviral treatment formulation at a concentration from about 0.03% to about 1.2% (v/v). The decellularization solution may include a solution of a polar aprotic solvent, such as dimethyl sulfoxide, benzyl alcohol and ethanol. | 09-18-2014 |
Steven A. Goldstein, Chicago, IL US
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20110009283 | IDENTIFICATION OF TOXIN LIGANDS - The disclosure relates to a method and system of screening for ligands which specifically bind to receptors. The method comprises expressing at least one receptor. The at least one receptor is contacted with a sample comprising at least one ligand. Whether the ligand selectively binds to the receptor is determined. | 01-13-2011 |
Steven A. Goldstein, Ann Arbor, MI US
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20090198184 | Percutaneous biomedical devices with regenerative materials interface - A percutaneous biomedical device comprising a body having a lumen extending longitudinally at least partially through the body, an implantable interface region disposed on the body, the implantable interface region having a plurality of radially extending conduits through the body, each of the conduits are in fluid communication with the lumen and in fluid communication with an exit port. The exit ports extrude a skin-interface composition between the subject's skin and the percutaneous biomedical device. Methods for implanting a percutaneous biomedical device includes implanting a percutaneous biomedical device percutaneously in a subject and aligning the exit ports of the implantable interface region between the epidermis and the hypodermis skin layers of the subject. | 08-06-2009 |
20100189792 | IN VIVO GENE TRANSFER METHODS FOR WOUND HEALING - The present invention relates to an in vivo method for specific targeting and transfer of DNA into mammalian repair cells. The transferred DNA may include any DNA encoding a therapeutic protein of interest. The invention is based on the discovery that mammalian repair cells proliferate and migrate into a wound site where they actively take up and express DNA. The invention further relates to pharmaceutical compositions that may be used in the practice of the invention to transfer the DNA of interest. Such compositions include any suitable matrix in combination with the DNA of interest. | 07-29-2010 |
20120100107 | IN VIVO TRANSFER METHODS FOR WOUND HEALING - The present invention relates to an in vivo method for specific targeting and transfer of DNA into mammalian repair cells. The transferred DNA may include any DNA encoding a therapeutic protein of interest. The invention is based on the discovery that mammalian repair cells proliferate and migrate into a wound site where they actively take up and express DNA. The invention further relates to pharmaceutical compositions that may be used in the practice of the invention to transfer the DNA of interest. Such compositions include any suitable matrix in combination with the DNA of interest. | 04-26-2012 |
Steven J. Goldstein, Madison, WI US
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20090104611 | METHODS OF WHOLE GENOME ANALYSIS - Methods are provided for ascertaining the sequence of a genomic DNA sample by nicking the DNA sample with a restriction nicking enzyme, followed by nick translation with labeled nucleotides, such that the labeled nucleotides can be quantified and compared to a known, reference genome. | 04-23-2009 |
Wayne Goldstein, Highland Park, IL US
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20120101584 | PATELLAR IMPLANT WITH VARIABLE WEIGHTS FOR KNEE REPAIR SURGERY - The present disclosure relates to a device for repairing a patient patella. The device comprises a patellar trial piece and a patellar implant. The patellar trial piece has selectable variable weights to correct mechanical properties of the patient patella. Such mechanical properties to be corrected include a moment of inertia and/or a center of gravity of the patient patella. The patellar implant has embedded weights correspond to the variable weights of the patellar trial piece. In one embodiment, the patellar trial piece has a plurality of variable weights to be inserted into a plurality of holes in the patellar trial piece. The weights are made of different materials. In another embodiment, the patellar trial piece has a rounded top surface and a substantially flat bottom surface with a plurality of pegs. The pegs are selected from pegs with variable weights that are made of different materials. | 04-26-2012 |
Wayne M. Goldstein, Highland Park, IL US
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20090326661 | IMPLANTABLE PATELLA COMPONENT HAVING A THICKENED SUPERIOR EDGE - An orthopaedic implant includes a patella component having a posterior bearing surface configured to articulate with the femoral condyles of a femur, and an anterior surface having a number of pegs extending outwardly therefrom. The superior edge of the patella component is thickened relative to conventional dome-shaped patella components. | 12-31-2009 |
20090326662 | IMPLANTABLE PATELLA COMPONENT HAVING A THICKENED SUPERIOR EDGE - An orthopaedic implant includes a patella component having a posterior bearing surface configured to articulate with the femoral condyles of a femur, and an anterior surface having a number of pegs extending outwardly therefrom. The superior edge of the patella component is thickened relative to conventional dome-shaped patella components. | 12-31-2009 |
20120123550 | IMPLANTABLE PATELLA COMPONENT HAVING A THICKENED SUPERIOR EDGE - An orthopaedic implant includes a patella component having a posterior bearing surface configured to articulate with the femoral condyles of a femur, and an anterior surface having a number of pegs extending outwardly therefrom. The superior edge of the patella component is thickened relative to conventional dome-shaped patella components. | 05-17-2012 |
Yehonathan Goldstein, Washington, DC US
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20100307239 | Food Preparation and Presentation Cylinder with Measurement Indicia - A food preparation and presentation cylinder with measurement indicia used for preparing and presenting food. The food preparation and presentation cylinder with measurement indicia can also be in the shape of a cube, a cone or other polygon. The cylinder is made of PYREX™, any type of transparent polypropylene or any transparent material. The cylinder can also be made of heat resistant and food grade material and is freezer safe, oven safe and microwave oven safe. The cylinder's measurement indicia can be a plurality of circumferential rings around the circumference of the cylinder or incremental etched markings on the front side and the back side of the cylinder. | 12-09-2010 |
Yeshayahu Goldstein, Gaithersburg, MD US
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20110113952 | Apparatus and method for the protection of a vehicle from rocket-propelled grenades - An apparatus for protecting a vehicle having a body from a rocket-propelled grenade (RPG), comprising a panel comprised of a plurality of spaced, generally parallel bars positioned in spaced outward relation to said body of said vehicle. | 05-19-2011 |
Yeshayahu S. Goldstein, Gaithersburg, MD US
Patent application number | Description | Published |
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20090193995 | INERTIAL DELAY FUSE - An inertial delay mechanism for use in an explosive projectile is provided. The delay mechanism consists of an inertial delay fuse that is precise, doesn't require sensitive primary explosives and doesn't utilize electronic circuitry. The inertial delay fuse includes a free sliding charge element that strikes an anvil located opposite to the sliding charge element. A delay gap is provided between the sliding charge element and the anvil. Upon impact, the sliding charge element slides forward and impacts the anvil, thereby inducing a shock wave in an initiator charge that subsequently results in detonation of main charges. The design is mechanically simple and robust enough to withstand severe g-loading forces that occur during firing and penetration of a projectile. | 08-06-2009 |
20130213252 | Inertial Delay Fuse - An inertial delay mechanism for use in an explosive projectile is provided. The delay mechanism consists of an inertial delay fuse that is precise, doesn't require sensitive primary explosives and doesn't utilize electronic circuitry. The inertial delay fuse includes a free sliding charge element that strikes an anvil located opposite to the sliding charge element. A delay gap is provided between the sliding charge element and the anvil. Upon impact, the sliding charge element slides forward and impacts the anvil, thereby inducing a shock wave in an initiator charge that subsequently results in detonation of main charges. The design is mechanically simple and robust enough to withstand severe g-loading forces that occur during firing and penetration of a projectile. | 08-22-2013 |
Yeshayahu Shyke Goldstein, Gaithersburg, MD US
Patent application number | Description | Published |
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20120107173 | SYSTEM AND METHOD FOR CHEMICAL AND BIOLOGICAL AGENT DECONTAMINATION - A system and method for decontamination of chemical and biological agents over terrain in an outdoor environment is provided that utilizes ultraviolet radiation to break up hydrogen peroxide into radical species that interact with chemical and biological agents to render them harmless. In a preferred embodiment, peroxide is dispersed in a contaminated area and the peroxide is then exposed to ultraviolet radiation that causes the peroxide to dissociate into radical species. The interaction of the radical species formed by the peroxide dissociation with the chemical and biological agents renders them useless. | 05-03-2012 |