Gleeson, US
Bentley F. Gleeson, Plymouth Meeting, PA US
Patent application number | Description | Published |
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20080308135 | Apparatus for cleaning stacked vessels with low head clearance - An apparatus for cleaning vessels stacked on racks with a minimum of head clearance. The cleaning apparatus has a drive unit with a turbine wheel connected to a multi-stage gear train. The output motion of the gear train connects through an angular transmission within a fluid conveying elbow to a rotatable housing having a rotatable nozzle angularly assembled thereto. The elbow has a pressure channel and a suction channel there through. The length of the apparatus from the elbow to the housing is short enough to be passed into the bunghole of a vessel, e.g. a wine barrel, while racked. A flexible suction hose is connected to a suction line in the apparatus for removing spent cleaning fluid from within the vessel. | 12-18-2008 |
20100051057 | Rotary apparatus and method for cleaning liquid storage tanks - A rotary apparatus and method is provided for cleaning liquid storage tanks, particularly above ground tanks. The rotary cleaning apparatus includes a Tee housing that is rotated around a vertical axis and a nozzle housing mounted to the Tee housing for rotation around a horizontal axis, resulting in a 360° spherical spray pattern. A set of downspray nozzles is mounted to the Tee housing at an angle to the vertical axis to rotate with the housing and generate a conical spray pattern. In the preferred embodiment, the apparatus draws liquid stored in the tank through a filter and pumps the filtered liquid through the rotary cleaning apparatus. | 03-04-2010 |
Brandon L. Gleeson, Fort Collins, CO US
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20140209070 | Heat Exchange in a Vehicle Engine System - In some aspects of what is described here, a heat exchanger has a first fuel port and a first heat transfer fluid port at a first end of an elongate heat exchanger body. The heat exchanger has a second fuel port and a second heat transfer fluid port at a second, opposite end of the elongate heat exchanger body. The heat exchanger has a fuel flow path that is straight between the first and second fuel ports, and a heat transfer fluid flow path that is straight between the first and second heat transfer fluid ports. The heat transfer fluid flow path is parallel to, and beside, the fuel flow path. The heat exchanger includes a heat transfer wall between the fuel flow path and the heat transfer fluid flow path. Fins extend from the heat transfer wall into the flow paths. | 07-31-2014 |
Brian Gleeson, Sewickley, PA US
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20110318604 | High-Temperature Coatings With Pt Metal Modified gamma-Ni + gamma'-Ni3Al Alloy Compositions - An alloy including a Pt-group metal, Ni and Al in relative concentration to provide a γ-Ni+γ′-Ni | 12-29-2011 |
Brian Gleeson, Ames, IA US
Patent application number | Description | Published |
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20080292490 | HIGH-TEMPERATURE COATINGS AND BULK ALLOYS WITH PT METAL MODIFIED GAMMA-NI + GAMMA'-NI3AL ALLOYS HAVING HOT-CORROSION RESISTANCE - An alloy including a Pt-group metal, Ni and Al, wherein the concentration of Al is limited with respect to the concentration of Ni and the Pt-group metal such that the alloy includes substantially no β-NiAl phase, and wherein the Pt-group metal is present in an amount sufficient to provide enhanced hot corrosion resistance. | 11-27-2008 |
20090324993 | HIGH-TEMPERATURE COATINGS AND BULK ALLOYS WITH PT METAL MODIFIED GAMMA-NI +GAMMA'-NI3AL ALLOYS HAVING HOT-CORROSION RESISTANCE - An alloy including a Pt-group metal, Ni and Al, wherein the concentration of Al is limited with respect to the concentration of Ni and the Pt-group metal such that the alloy includes substantially no β-NiAl phase, and wherein the Pt-group metal is present in an amount sufficient to provide enhanced hot corrosion resistance. | 12-31-2009 |
20110197999 | METHODS FOR MAKING HIGH-TEMPERATURE COATINGS HAVING PT METAL MODIFIED GAMMA-NI +GAMMA'-NI3AL ALLOY COMPOSITIONS AND A REACTIVE ELEMENT - A method for making an oxidation resistant article, including (a) depositing a layer of a Pt group metal on a substrate to form a platinized substrate; and (b) depositing on the platinized substrate layer of Pt group metal a layer of a reactive element selected from the group consisting of Hf, Y, La, Ce and Zr and combinations thereof to form a surface modified region thereon, wherein the surface modified region includes the Pt-group metal, Ni, Al and the reactive element in relative concentration to provide a γ-Ni+γ-Ni3Al phase constitution. | 08-18-2011 |
20110229735 | HIGH-TEMPERATURE COATINGS WITH PT METAL MODIFIED GAMMA-NI+GAMMA'-NI3AL ALLOY COMPOSITIONS - An alloy including a Pt-group metal, Ni and Al in relative concentration to provide a γ-Ni+γ′-Ni | 09-22-2011 |
20110229736 | HIGH-TEMPERATURE COATINGS WITH PT METAL MODIFIED GAMMA-NI+GAMMA'-NI3AL ALLOY COMPOSITIONS - An alloy including a Pt-group metal, Ni and Al in relative concentration to provide a γ-Ni+γ′-Ni | 09-22-2011 |
Brian M. Gleeson, Sewickley, PA US
Patent application number | Description | Published |
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20100012235 | Pt METAL MODIFIED y-Ni + y'-Ni3Al ALLOY COMPOSITIONS FOR HIGH TEMPERATURE DEGRADATION RESISTANT STRUCTURAL ALLOYS - An alloy comprising 5 at % ≦Al<16 at %, about 0.05 at % to 1 at % of a reactive element selected from the group consisting of Hf, Y, La, Ce, Zr, and combinations thereof, and Ni, wherein the alloy composition has a predominately γ-Ni+γ′-Ni | 01-21-2010 |
20100028712 | y'-Ni3Al MATRIX PHASE Ni-BASED ALLOY AND COATING COMPOSITIONS MODIFIED BY REACTIVE ELEMENT CO-ADDITIONS AND Si - An alloy including about 16 at % to about 23 at % Al; about 3 at % to about 10 at % Cr; up to about 5 at % Si; up to about 0.3 at % of at least two reactive elements selected from Y, Hf, Zr, La, and Ce; and Ni. The alloy has a volume fraction of γ′-Ni | 02-04-2010 |
Daniel James Gleeson, Frederica, DE US
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20160097172 | PORTABLE FLEXIBLE SEALING DEVICE FOR GRATED OPENINGS - A lightweight watertight cover that is easily installed and positively secured in place, which provides a reliable seal to prevent flood water from entering openings such as subway ventilation shaft gratings and other porous openings that serve as entry point for flood water. | 04-07-2016 |
Eamon Patrick Gleeson, Atlanta, GA US
Patent application number | Description | Published |
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20080288120 | Methods and Systems for Modifying Turbine Control Systems - Methods and systems for modifying a turbine control system may be provided for. A method may include replacing at least one legacy main controller processor communicating in a first communication protocol with a current main control processor communicating in a second communication protocol, retaining at least one legacy IO processor in communication with at least one turbine monitoring device communicating in the first communication protocol, and providing at least one converter in communication with the current main controller processor or processors and in communication with the legacy IO processor or processors. The converter may translate communications between the current main controller processor or processors and the legacy IO processor or processors by translating between the second communication protocol and the first communication protocol. | 11-20-2008 |
Garrett Gleeson, Carlsbad, CA US
Patent application number | Description | Published |
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20120239096 | INSTRUMENT AND METHOD FOR SPINAL COMPRESSION AND DISTRACTION - An instrument for multilevel compression and distraction of vertebrae in a spinal column includes a first arm, a second arm, a third arm, a linking member, and a coupler. The first arm includes a distal end with a first aperture for receiving a first screw extender that attaches to a first vertebra. The second arm includes a distal end with a second aperture for receiving a second screw extender that attaches to a second vertebra. The third arm includes a distal end with a third aperture for receiving a third screw extender that attaches to a third vertebra. The linking member pivotally links proximal ends of the first, second, and third arms. The coupler positions the distal ends of the first arm and the second arm relative to the third arm to compress and distract the first vertebra and the second vertebra relative to the third vertebra. | 09-20-2012 |
20140316475 | SPINAL DEFORMITY CORRECTION INSTRUMENTS AND METHODS - An instrument for correction of spinal deformities includes an inner member with a proximal portion configured to receive a corrective force and a distal coupling portion configured to transfer the corrective force to a spinal implant in a vertebra. A slot extends transversely through the coupling portion and is configured to guide a fixation rod into the spinal implant. A threaded sleeve includes an external thread and a thru-bore that slides relative to the proximal portion. An outer member couples with the proximal portion and threadably engages the external thread to apply a reduction force as the outer member rotates relative to the inner member. A reduction blade includes a proximal interlocking portion that removably couples with the threaded sleeve and a distal rod engagement feature configured to engage the fixation rod and transfer the reduction force to reduce the fixation rod into the spinal implant. | 10-23-2014 |
Garrett Gleeson, Encinitas, CA US
Patent application number | Description | Published |
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20130110184 | SYSTEMS FOR VERTEBRAL ADJUSTMENTS AND ROD REDUCTION | 05-02-2013 |
20130289633 | INSTRUMENT AND METHOD FOR SPINAL COMPRESSION AND DISTRACTION - An orthopedic instrument for compression and distraction of bone segments includes a first receiver, a second receiver, a positioner member, and a guide member. The first receiver includes a first receiver aperture that receives a first screw extender. The second receiver includes a second extender aperture that receives a second screw extender. The positioner member translates the second receiver relative to the first receiver to apply one of a compression and a distraction force on the screw extenders. The guide member parallel to the positioner member guides the second receiver relative to the first receiver. | 10-31-2013 |
20150066091 | SYSTEMS FOR VERTEBRAL ADJUSTMENTS AND ROD REDUCTION - An instrument for compression and distraction of a vertebral segment and reducing a surgical rod includes a first arm, a second arm, a coupler, and a reducer. The first arm includes a first aperture for receiving a first screw extender that attaches to a first vertebra. The second arm pivotably couples to the first arm and includes a second aperture for receiving a second screw extender that attaches to a second vertebra. The coupler links the first arm to the second arm to position the first arm relative to the second arm for compression and distraction of the first vertebra relative to the second vertebra. The reducer is received within the second aperture for reducing a surgical rod within the second screw extender. | 03-05-2015 |
James A. Gleeson, Alta Loma, CA US
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20080203365 | Fiber Cement Building Materials With Low Density Additives - This invention relates to a formulation with the addition of low density additives of volcanic ash, hollow ceramic microspheres or a combination of microspheres and volcanic ash or other low density additives into cementitious cellulose fiber reinforced building materials. This formulation is advantageously lightweight or low density compared as compared to current fiber cement products without the increased moisture expansion and freeze-thaw degradation usually associated with the addition of lightweight inorganic materials to fiber cement mixes. The low density additives also give the material improved thermal dimensional stability. | 08-28-2008 |
20100242802 | Fiber cement building materials with low density additives - This invention relates to a formulation with the addition of low density additives of volcanic ash, hollow ceramic microspheres or a combination of microspheres and volcanic ash or other low density additives into cementitious cellulose fiber reinforced building materials. This formulation is advantageously lightweight or low density compared as compared to current fiber cement products without the increased moisture expansion and freeze-thaw degradation usually associated with the addition of lightweight inorganic materials to fiber cement mixes. The low density additives also give the material improved thermal dimensional stability. | 09-30-2010 |
20120260827 | FIBER CEMENT BUILDING MATERIALS WITH LOW DENSITY ADDITIVES - This invention relates to a formulation with the addition of low density additives of volcanic ash, hollow ceramic microspheres or a combination of microspheres and volcanic ash or other low density additives into cementitious cellulose fiber reinforced building materials. This formulation is advantageously lightweight or low density compared as compared to current fiber cement products without the increased moisture expansion and freeze-thaw degradation usually associated with the addition of lightweight inorganic materials to fiber cement mixes. The low density additives also give the material improved thermal dimensional stability. | 10-18-2012 |
James B. Gleeson, Columbus, OH US
Patent application number | Description | Published |
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20120282681 | Rapid Identification of Organisms in Bodily Fluids - There is provided a device that retains a collected sample for on-demand testing of a small portion of the collected sample while the rest of the sample remains for optional additional analysis. The on-demand test provides relatively immediate information about aspects of the sample, e.g. presence of microbes, chemistry, nutritional condition, presence of contaminants. | 11-08-2012 |
20130102772 | SYSTEMS, METHODS AND DEVICES FOR PRODUCING, MANUFACTURING AND CONTROL OF RADIOPHARMACEUTICALS-FULL - Systems, methods, and devices for generating radionuclides for use in production of radiopharmaceuticals; synthesizing the radionuclides generated and removing any unwanted products; measuring the quantity and activity level of the synthesized radionuclides; distributively delivering the radionuclides in appropriate quantities to modular cassette synthesis units in a modular cassette subsystem for contemporaneous/parallel production of radiopharmaceutical output and that allow reuse and/or quick, safe, and disposable replacement of portions of the subsystem; delivering non-radionuclide components to the modular cassette synthesis units as part of production of radiopharmaceutical output; measuring the quantity and activity level of each stream of radiopharmaceutical output; purifying the radiopharmaceutical output; dispensing individual doses in sterile vial(s); automatically producing labeling and dose related information; performing automated quality control on extracted samples of produced radiopharmaceutical output; and providing software and hardware controls for overall and sub-portion operation for optional remote data collection, communication, and/or control. | 04-25-2013 |
20150313677 | REMOTE MANIPULATOR DEVICE - A system for operating a catheter having a distal end adapted to be navigated in the body, and a proximal end having a handle with a translatable control and a rotatable control for acting on the distal end of the device includes a support for receiving and engaging the handle of the catheter; a translation mechanism for advancing and retracting the support to advance and retract a catheter whose handle is received in the support; a rotation mechanism for rotating the support to rotate a catheter whose handle is received in the support; a translation operator for engaging the translatable control of a catheter whose handle is received in the support and operating the translatable control to act on the distal end of the device; and a rotation operator for engaging the rotatable control of a catheter whose handle is received in the support and operating the rotatable control to act on the distal end of the device. | 11-05-2015 |
James T. Gleeson, Kent, OH US
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20080303376 | DEVICES AND METHODS FOR ENERGY CONVERSION BASEDON THE GIANT FLEXOELECTRIC EFFECT IN NON-CALAMITIC LIQUID CRYSTALS - Devices and methods for energy conversion based on the giant flexoelectric effect in non-calamitic liquid crystals. By preparing a substance comprising at least one type of non-calamitic liquid crystal molecules and stabilizing the substance to form a mechanically flexible material, flexible conductive electrodes may be applied to the material to create an electro-mechanical energy conversion device which relies on the giant flexoelectric effect to produce electrical and/or mechanical energy that is usable in such applications as, for example, power sources, energy dissipation, sensors/transducers, and actuators. The ability to directly and accurately measure the giant flexoelectric effect for different types of non-calamitic liquid crystal molecules is important for identifying molecules that may be effective for particular applications. | 12-11-2008 |
20100182026 | METHODS AND SYSTEMS FOR DETERMINING FLEXOELECTRIC EFFECT IN A LIQUID CRYSTAL - There are provided methods for creating energy conversion devices based on the giant flexoelectric effect in non-calamitic liquid crystals. By preparing a substance comprising at least one type of non-calamitic liquid crystal molecules and stabilizing the substance to form a mechanically flexible material, flexible conductive electrodes may be applied to the material to create an electro-mechanical energy conversion device which relies on the giant flexoelectric effect to produce electrical and/or mechanical energy that is usable in such applications as, for example, power sources, energy dissipation, sensors/transducers, and actuators. | 07-22-2010 |
20100207493 | ELECTRO-MECHANICAL ENERGY CONVERSION DEVICES AND SYSTEMS - There are provided methods for creating energy conversion devices based on the giant flexoelectric effect in non-calamitic liquid crystals. By preparing a substance comprising at least one type of non-calamitic liquid crystal molecules and stabilizing the substance to form a mechanically flexible material, flexible conductive electrodes may be applied to the material to create an electro-mechanical energy conversion device which relies on the giant flexoelectric effect to produce electrical and/or mechanical energy that is usable in such applications as, for example, power sources, energy dissipation, sensors/transducers, and actuators. | 08-19-2010 |
James W. Gleeson, Burke, VA US
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20110083994 | Onset haze measurement apparatus and procedure - An apparatus and method for determining at least one of the temperatures at which a petroleum product will manifest delayed haze and the temperature at which haze will not exist in the product is provided. The apparatus comprises a container for holding a sample of the product, a light source, light detector, heaters and coolers combined with microprocessor means for storing and analyzing at least one of light transmitted or scattered by the sample. Measurements are useful in determining the haze properties of the product and also for controlling a dehazing process to meet target haze properties. | 04-14-2011 |
20110083995 | Method for haze mitigation and filterability improvement base stocks - The present invention is a process for removing waxy haze from and improving the filterability of base stocks including heavy mineral oil base stocks, gas-to-liquids (GTL) and hydrodewaxed or hydroisomerized waxy feed basestocks by filtering the waxy haze causing particles out of the base stock employing a filter characterized by a high surface area of pores accessible to the haze wax particles which have particles dimensions of no more than about 5 microns. | 04-14-2011 |
James William Gleeson, Burke, VA US
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20090186786 | Method for haze mitigation and filterability improvement for gas-to-liquid hydroisomerized base stocks - Haze formation in heavy Gas-to-Liquids (GTL) base stock is mitigated by the addition to said GTL base stock of one or more particular additives. | 07-23-2009 |
20100236990 | Bubble separation to remove haze and improve filterability of lube base stocks - Provided is a bubble generating process used to treat dewaxed lube base stocks to improve their filterability, hazy appearance or both. In one form, the process for improving at least one of haze appearance and filterability of a dewaxed lubricating oil basestock contained in a storage vessel includes contacting the lubricating oil basestock with gas bubbles passed through a gas distribution grid for a time sufficient to form a mixture of froth and gas treated basestock, allowing the mixture of froth and gas treated basestock to settle for a time sufficient to form a froth layer and a gas treated basestock layer, and separating the froth layer from the gas treated basestock layer, wherein a basestock having improved haze, improved filterability or both may be isolated from the gas treated basestock layer. | 09-23-2010 |
Jim Gleeson, Columbus, OH US
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20120222774 | CLOSED VIAL FILL SYSTEM FOR ASEPTIC DISPENSING - A closed path vial fill system includes a bulk product vial, a peristaltic pump operated by a stepper motor, a dispensing manifold assembly to which may be coupled at least one final product vial, an optional quality check station, and an optional waste collection system. A concentration, activity, and volume (CAV) sensor may be incorporated into the system to receive a radiopharmaceutical product directly from a synthesizing unit. A control system may be integrated into the system to provide automated control of various aspects of the radiopharmaceutical dispensing process. The system is used to aseptically dispense finished radiopharmaceuticals into receiving vessels, such as a Quality Control vial, a sterility vial, and/or final product vials, while providing users an efficient means for removing and discarding contaminated disposable components. | 09-06-2012 |
Joseph G. Gleeson, San Diego, CA US
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20120278909 | COMPOSITIONS AND METHODS FOR DETERMINING GENETIC POLYMORPHISMS IN THE TMEM216 GENE - In alternative embodiments, the invention provides nucleic acid sequences that are genetic polymorphic variations of the human TMEM216 gene, and TMEM216 polypeptide encoded by these variant alleles. In alternative embodiments, the invention provides methods of determining or predicting a predisposition to, or the presence of, a ciliopathy (or any genetic disorder of a cellular cilia or cilia anchoring structure, basal body or ciliary function) in an individual, such as a Joubert Syndrome (JS), a Joubert Syndrome Related Disorder (JSRD) or a Meckel Syndrome (MKS). In alternative embodiments, the invention provides compositions and methods for the identification of genetic polymorphic variations in the human TMEM216 gene, and methods of using the identified genetic polymorphisms and the proteins they encode, e.g., to screen for compounds that can modulate the human TMEM216 gene product, and possibly treat JS, JSRD or MKS. In alternative embodiments, the invention provides cells, cell lines and/or non-human transgenic animals that can be used as screening or model systems for studying ciliopathies and testing various therapeutic approaches in treating ciliopathies, e.g., JS, JSRD or MKS. | 11-01-2012 |
20140072975 | COMPOSITIONS AND METHODS FOR DETERMINING GENETIC POLYMORPHISMS IN THE TMEM216 GENE - In alternative embodiments, the invention provides nucleic acid sequences that are genetic polymorphic variations of the human TMEM216 gene, and TMEM216 polypeptide encoded by these variant alleles. In alternative embodiments, the invention provides methods of determining or predicting a predisposition to, or the presence of, a ciliopathy (or any genetic disorder of a cellular cilia or cilia anchoring structure, basal body or ciliary function) in an individual, such as a Joubert Syndrome (JS), a Joubert Syndrome Related Disorder (JSRD) or a Meckel Syndrome (MKS). In alternative embodiments, the invention provides compositions and methods for the identification of genetic polymorphic variations in the human TMEM216 gene, and methods of using the identified genetic polymorphisms and the proteins they encode, e.g., to screen for compounds that can modulate the human TMEM216 gene product, and possibly treat JS, JSRD or MKS. | 03-13-2014 |
Margaret M. Gleeson, Berkeley Heights, NJ US
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20110166352 | PROCESS FOR MAKING STERILE ARIPIPRAZOLE OF DESIRED MEAN PARTICLE SIZE - A process is provided for making sterile aripiprazole having an average particle size less than 100 microns but preferably greater than 25 microns employing an impinging jet crystallization procedure. The resulting bulk aripiprazole of desired particle size may be used to form a sterile freeze-dried aripiprazole formulation, which upon constitution with water and intramuscular injection releases aripiprazole over a period of at least about one week and up to about eight weeks. | 07-07-2011 |
20130161848 | PROCESS FOR MAKING STERILE ARIPIPRAZOLE OF DESIRED MEAN PARTICLE SIZE - A process is provided for making sterile aripiprazole having an average particle size less than 100 microns but preferably greater than 25 microns employing an impinging jet crystallization procedure. The resulting bulk aripiprazole of desired particle size may be used to form a sterile freeze-dried aripiprazole formulation, which upon constitution with water and intramuscular injection releases aripiprazole over a period of at least about one week and up to about eight weeks. | 06-27-2013 |
Martin A. Gleeson, San Diego, CA US
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20090326208 | Methods and compositions for generating recombinant nucleic acid molecules - A method of generating a double stranded (ds) recombinant nucleic acid molecule covalently linked in both strands by contacting two or more ds nucleotide sequences with a topoisomerase under conditions such that both termini of at least one end of a first ds nucleotide sequence are covalently linked by the topoisomerase to both termini of at least one end of a second ds nucleotide sequence is provided. Also provided is a method for generating a ds recombinant nucleic acid molecule covalently linked in one strand, by contacting two or more ds nucleotide sequences with a type IA topoisomerase under conditions such that one strand, but not both strands, of one or both ends of a first ds nucleotide sequence are covalently linked by the topoisomerase. Compositions for performing such methods, and compositions generated from such methods also are provided, as are kits containing components useful for conveniently practicing the methods. | 12-31-2009 |
Martin A.g. Gleeson, San Diego, CA US
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20080241889 | METHODS AND COMPOSITIONS FOR SYNTHESIS OF NUCLEIC ACID MOLECULES USING MULTIPLE RECOGNITION SITES - The present invention provides compositions and methods for recombinational cloning. The compositions include vectors having multiple recombination sites and/or multiple topoisomerase recognition sites. The methods permit the simultaneous cloning of two or more different nucleic acid molecules. In some embodiments the molecules are fused together while in other embodiments the molecules are inserted into distinct sites in a vector. The invention also generally provides for linking or joining through recombination a number of molecules and/or compounds (e.g., chemical compounds, drugs, proteins or peptides, lipids, nucleic acids, carbohydrates, etc.) which may be the same or different. The invention also provides host cells comprising nucleic acid molecules of the invention or prepared according to the methods of the invention, and also provides kits comprising the compositions, host cells and nucleic acid molecules of the invention, which may be used to synthesize nucleic acid molecules according to the methods of the invention. | 10-02-2008 |
Martin Anthony Gleeson, San Diego, CA US
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20100190175 | METHODS OF RANDOM MUTAGENESIS AND METHODS OF MODIFYING NUCLEIC ACIDS USING TRANSLESION DNA POLYMERASES - The invention is related generally to methods of amplifying or synthesizing or producing nucleic acid molecules using Translesion DNA polymerases. In particular, the invention relates to methods of introducing a random mutation into a nucleic acid and encoded polypeptide using Translesion DNA polymerases. The invention also relates to methods of introducing a modified nucleotide into a nucleic acid using Translesion DNA polymerases. The invention also relates to mutagenized and modified nucleic acid molecules and proteins produced by these methods, and to fragments or derivatives thereof. The invention also relates to vectors and host cells comprising mutagenized nucleic acid molecules, fragments, or derivatives. The invention also relates to the use of mutagenized nucleic acid molecules to produce desired polypeptides and uses of modified nucleic acid molecules to analyze samples. The invention also relates to kits or compositions or compounds for use in the invention or for carrying out the invention. | 07-29-2010 |
20130295688 | OPTICAL ANALYTE DETECTION SYSTEMS AND METHODS OF USE - Various embodiments are drawn to systems and methods for detecting an analyte of interest in a sample including an optical sensor, a capture probe attached to a surface of the optical sensor wherein the capture probe is capable of binding to the analyte to form a duplex or complex, and an antibody capable of binding to the analyte, duplex, or complex. In several embodiments, systems and methods further include a particle attached to the antibody or capable of binding to the antibody. In several embodiments, systems and methods for analyte detection feature one or more of the following: high detection sensitivity and specificity, scalability and multiplex capacity, ability to analyze large analytes, and ability to detect or measure multiple individual binding events in real-time. | 11-07-2013 |
Matt Gleeson, San Francisco, CA US
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20110055343 | METHOD AND APPARATUS FOR FILTERING EMAIL SPAM USING EMAIL NOISE REDUCTION - A method and system for filtering email spam using email noise reduction are described. In one embodiment, the method includes detecting, in an email message, data indicative of noise added to the email message to avoid spam filtering. The method further includes modifying the content of the email message to reduce the noise, and comparing the modified content of the email message with the content of a spam message. | 03-03-2011 |
Michael Gleeson, Salt Lake City, UT US
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20080221993 | CAROUSEL ADVERTISING SYSTEM - Advertising system that adheres printed indicia to surfaces are described. The advertising system can contain a substrate containing the printed indicia layer and an adhesive layer. A protective layer, formed of a substantially clear or transparent material, can be used protect an exterior surface of the substrate. The printed indicia may be coated, screen printed, transfer laminated, etc., to the underlying surface to which the advertising system is attached, as can the protective layer and the adhesive layer when present. The advertising system can be used on non-durable surfaces, as well as surfaces which are exposed to extreme conditions and/or continuous wear have. The advertising system can also be used with moving and non-moving, vertical and horizontal surfaces. The advertising systems also allow application and removal of advertisements quickly and effectively without removing, mechanically altering, or damaging the surfaces to which they are applied. Other embodiments are described. | 09-11-2008 |
Michael B. Gleeson, Salt Lake City, UT US
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20110217674 | MANDIBULAR MANIPULATOR - Described is a mandibular manipulator instrument as a standalone tool or with associated mouthpiece that includes two interlocking laterally sliding frames comprising a movable upper and a lower incisor pull, shaped for receiving a patient's central incisor teeth and a pair of pinion shafts for driving the upper and lower incisor pulls. A screw thread is used to provide a precise lateral motion for the sagittal measurement. The mouthpiece is constructed of resilient rubber. The manipulator may be positioned and held in a resilient flexible mouthpiece by means of the two pinions protruding through acoustically tight apertures respective to each pinion's position. The manipulator can be used for other application in an embodiment without the mouthpiece and/or in combination with a bite registration shape that is part of the manipulator frame. | 09-08-2011 |
20130023797 | MANDIBULAR MANIPULATOR AND RELATED METHODS - Described is a mandibular manipulator instrument as a standalone tool or with associated mouthpiece that includes two interlocking laterally sliding frames comprising a movable upper and a lower incisor pull, shaped for receiving a patient's central incisor teeth and a pair of pinion shafts for driving the upper and lower incisor pulls. A screw thread is used to provide a precise lateral motion for the sagittal measurement. The mouthpiece is constructed of resilient rubber. The manipulator is positioned and held in the resilient rubber mouthpiece by means of the two pinions protruding through acoustically tight apertures respective to each pinion's position. The manipulator can be used for other applications in an embodiment without the mouthpiece and/or in combination with a bite registration shape that is part of the manipulator frame. | 01-24-2013 |
20140114146 | DIAGNOSTIC DEVICES, MANDIBULAR MANIPULATORS WITH TONGUE AND NASAL SENSORS, AUTOMATED MANDIBULAR MANIPULATORS AND RELATED METHODS - Diagnostic devices may include features for determining at least one of bilateral nasal flow and tongue position. Automated mandibular manipulators may include at least one motor including a feedback feature for communicating at least one position of at least a portion of the mandibular manipulator to a computer. | 04-24-2014 |
Michael Patrick Gleeson, San Clemente, CA US
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20130115201 | Fluid Supplement with Prenatal Vitamins - A fluid supplement is provided that is specifically tailored to meet the health and nutritional needs of a pregnant woman and her developing fetus. The fluid supplement also combats the symptoms of nausea and vomiting that are commonly associated with pregnancy. The fluid supplement contains vitamins, minerals, dietary supplements, and flavor-enhancing ingredients in amounts that safely provide health and nutritional benefits to both the woman and her developing fetus. By using the fluid supplement, a pregnant woman is able to obtain the health and nutritional benefits in a single dose of a palatable fluid supplement instead of having to swallow multiple pills per day. | 05-09-2013 |
Paul James Gleeson, Torrance, CA US
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20110281439 | APPLYING WAFER BACKSIDE COATINGS TO SEMICONDUCTOR WAFERS - A method for coating a silicon wafer comprises depositing a coating onto the exposed side of the wafer such that the coating is deposited on the entire surface area of the exposed side of the wafer, reaching to the edge of the wafer. This method either reduces significantly or eliminates die-fly during dicing of semiconductor wafers, and is effective for depositing thin layers, such as are needed for Al paste electrodes in solar cell fabrication. | 11-17-2011 |
Sean Gleeson, Pittsford, NY US
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20120056042 | TRACKING ROLLING STOCK IN A CONTROLLED AREA OF A RAILWAY SYSTEM - A system for monitoring the location of rolling stock within a controlled area of a railway system is provided. The system includes a plurality of axle counters within the controlled area, wherein the axle counts are associated with a global sequence identifier. A central controller processes the axle counts and associated global sequence identifier in conjunction with a list of rolling stock entering the controlled area to provide a real time map of the location of each piece of rolling stock within the controlled area. | 03-08-2012 |
Sean Gleeson, Upper Arlington, OH US
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20140095096 | NON-DESTRUCTIVE THERMOGRAPHIC WELD INSPECTION - A non-destructive system for characterizing welds that includes at least one weldment that further includes at least two components joined together a weld; at least one source of heat energy directed toward one side of the weldment, wherein the source of heat energy is operative to direct a predetermined amount of heat energy through the first component toward one side of the weld, through the weld and the area surrounding the weld, and through the second component to the opposite side of the weldment, and wherein the heat energy is sufficient to induce a temperature change in the weld and the area surrounding the weld; and a temperature measuring device directed toward the opposite side of the weldment for gathering temperature data from heat passing through the second component away from the weld and the area surrounding the weld, wherein the gathered temperature data is indicative of weld quality. | 04-03-2014 |
20140375169 | ACOUSTIC COUPLING SHOES FOR USE IN INSPECTING NON-FLAT SURFACES - A system for inspecting the surface of a curved object is provided. This system includes an object having a curved surface; at least one substantially flat interdigital transducer, wherein the interdigital transducer is operative to generate surface energy waves; and at least one coupling device disposed between the curved surface and the substantially flat interdigital transducer, wherein the coupling device is operative to conform to the curved surface, support the interdigital transducer, and provide a medium through which the surface energy waves can effectively travel from the interdigital transducer to the curved surface and across the curved surface in a predetermined direction. | 12-25-2014 |
Sean T. Gleeson, Columbus, OH US
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20140165730 | PORTABLE MATRIX PHASED ARRAY SPOT WELD INSPECTION SYSTEM - A portable system for non-destructively characterizing spot welds that includes at least one matrix phased array probe and a body, wherein the body is designed to be hand-held and further includes an ergonomically designed outer casing; at least one input for connecting to the at least one matrix phased array probe; ultrasonic phased array transmitting and receiving circuitry in electrical communication with the at least one input; a touch screen computer that further includes at least one data processor running software that includes at least one imaging algorithm for processing data received from the probe and generating color coded ultrasonic C-scan images of characterized welds; and at least one monitor for displaying the color coded ultrasonic C-scan images of the characterized welds in real time. | 06-19-2014 |
Shaun Francis Gleeson, Kansas City, MO US
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20150344979 | HIDE ROUTING SYSTEMS AND METHODS - Methods and systems for processing raw animal hides into leather are provided. In particular, one or more embodiments comprise a tanning manager that directs the routing of hides to a plurality of tanning drums. This allows the tanning manager to efficiently use the capacity of the plurality of tanning drums and provides improved consistency in the tanning of the hides. Furthermore, one or more embodiments enable the tanning manager to route hides to tanning drums based on various factors, such as hide type, hide weight, and hide size. In addition, one or more embodiments provide the tanning manager with greater control over the processing of hides into leather by customizing the tanning recipes applied to each batch of hides. | 12-03-2015 |
Tom J. Gleeson, Dekalb, IL US
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20110010192 | MEDICAL IMAGE METADATA PROCESSING - Enhanced techniques for the extraction and use of metadata from medical images are disclosed herein. Based on the information in the metadata, specific processing may be performed within an image order management system, radiology information system (RIS), or like system involved with healthcare imaging. In one specific embodiment, a radiology read order may be created, pre-populated, and transmitted via a processing system (e.g., a teleradiology image order management system) based on the metadata within the radiology image. For example, this metadata may exist within the header of a DICOM-formatted image data file or a DICOM communication protocol transmission. The processing system may then provide the pre-populated read order back to the source of the medical images for verification and submission. Other processing actions may also occur based on information extracted from the image metadata, such as custom workflows and handling based on an originating facility, or transferring the images to a particular radiologist or location. | 01-13-2011 |
20120265551 | MEDICAL IMAGE METADATA PROCESSING - Enhanced techniques for the extraction and use of metadata from medical images are disclosed herein. Based on the information in the metadata, specific processing may be performed within an image order management system, radiology information system (RIS), or like system. A radiology read order may be created, pre-populated, and transmitted via a processing system (e.g., a teleradiology image order management system) based on the metadata within the radiology image. For example, this metadata may exist within the header of a DICOM-formatted image data file or a DICOM communication protocol transmission. The processing system may then provide the pre-populated read order back to the source of the medical images for verification and submission. Other processing actions may also occur based on information extracted from the image metadata, such as custom workflows and handling based on an originating facility, or transferring the images to a particular radiologist or location. | 10-18-2012 |
20120310668 | ORGANIZING MEDICAL IMAGES FOR DISPLAY - The subject matter of this specification can be implemented in, among other things, a system for interfacing with multiple medical imaging modalities that includes a manifest generator for generating a manifest of medical images. The manifest can be used to determine an ordering or a layout of the medical images generated by the modalities, optionally as a function of the modality type, anatomical area, and other variables. In some embodiments, the various medical images and metadata may be received at an image order management system that parses the metadata and assembles the metadata into the manifest files that may be transmitted independently to remote interpretation sites, which in turn may be equipped with image viewer applications that analyze the manifest files and determine a rearranged ordering and/or grouping of the medical images, wherein the rearrangement is executed as a function of modality, anatomy, orientation and other variables. | 12-06-2012 |
20140142983 | MEDICAL IMAGE METADATA PROCESSING - Enhanced techniques for the extraction and use of metadata from medical images are disclosed herein. Based on the information in the metadata, specific processing may be performed within an image order management system, radiology information system (RIS), or like system. A radiology read order may be created, pre-populated, and transmitted via a processing system (e.g., a teleradiology image order management system) based on the metadata within the radiology image. For example, this metadata may exist within the header of a DICOM-formatted image data file or a DICOM communication protocol transmission. The processing system may then provide the prepopulated read order back to the source of the medical images for verification and submission. Other processing actions may also occur based on information extracted from the image metadata, such as custom workflows and handling based on an originating facility, or transferring the images to a particular radiologist or location. | 05-22-2014 |
Tom J. Gleeson, Madison, WI US
Patent application number | Description | Published |
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20100211409 | ORGANIZING MEDICAL IMAGES FOR DISPLAY - The subject matter of this specification can be implemented in, among other things, a system for interfacing with multiple medical imaging modalities that includes a manifest generator for generating a manifest of medical images. The manifest can be used to determine an ordering or a layout of the medical images generated by the modalities, optionally as a function of the modality type, anatomical area, and other variables. In some embodiments, the various medical images and metadata may be received at an image order management system that parses the metadata and assembles the metadata into the manifest files that may be transmitted independently to remote interpretation sites, which in turn may be equipped with image viewer applications that analyze the manifest files and determine a rearranged ordering and/or grouping of the medical images, wherein the rearrangement is executed as a function of modality, anatomy, orientation and other variables. | 08-19-2010 |
20110222746 | DISPLAYING RADIOLOGICAL IMAGES - The subject matter of this specification can be implemented in, among other things, a system for interfacing with multiple medical imaging modalities that includes a normalization module for normalizing hanging protocols for displaying medical images. The normalization can be executed as a function of similar image characteristics shared between multiple sequences of medical images. | 09-15-2011 |