Patent application number | Description | Published |
20130244955 | BINDING PROTEINS FOR HEPCIDIN - The present invention relates to novel, specific-binding therapeutic and/or diagnostic proteins directed against Hepcidin, which proteins preferably are muteins of a lipocalin protein. The invention also relates to nucleic acid molecules encoding such proteins and to methods for generation and use of such proteins and nucleic acid molecules. Accordingly, the invention also is directed to pharmaceutical and/or diagnostic compositions comprising such a lipocalin proteins, including uses of these proteins. | 09-19-2013 |
20140323389 | METHODS FOR PREVENTING OR TREATING DISORDERS BY INCREASING BIOAVAILABILITY OF IRON AND RELATED PHARMACEUTICAL FORMULATION - The present disclosure relates to methods of treating, ameliorating or preventing a disorder comprising administering a therapeutically effective amount of a composition to a subject in need thereof, which composition contains a lipocalin mutein or a fragment or a variant thereof capable of increasing the bioavailability of iron in the subject. | 10-30-2014 |
20150291675 | HUMAN NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN (HNGAL) MUTEINS THAT BIND HEPCIDIN AND NUCLEIC ACID ENCODING SUCH - The present invention relates to novel, specific-binding therapeutic and/or diagnostic proteins directed against Hepcidin, which proteins preferably are muteins of lipocalin protein. The invention also relates to nucleic acid molecules encoding such proteins and to methods for generation and use of such proteins and nucleic acid molecules. Accordingly, the invention also is directed to pharmaceutical and/or diagnostic compositions comprising such a lipocalin proteins, including uses of these proteins. | 10-15-2015 |
Patent application number | Description | Published |
20100265461 | GONIOSCOPE FOR IMPROVED VIEWING - Various embodiments relate to opthalmoscopic devices, systems and methods for viewing the anterior chamber, trabecular meshwork, iris root, scleral spur, and/or related nearby structures in the eye. In some embodiments, devices, systems and/or methods may employ a plurality of gonioscopic optical elements that form a virtual image that can be imaged by a microscope directly in front of a patient (e.g., without tilting the patient's head). Various embodiments described herein may be useful for opthalmologic diagnoses, treatments, monitoring and/or surgical procedures. Some embodiments include a gonioscopic attachment configured to attach to a conventional gonioscope and redirect light emitted by the gonioscope. Various embodiments described herein can be incorporated into disposable, single-use gonioscopes. | 10-21-2010 |
20110224661 | MINIMALLY INVASIVE SURGICAL SYSTEM FOR CO2 LASERS - A Minimally Invasive Surgical Laser Hand-piece (“MISLH”) for use with a probe is described. The MISLH has a MISLH proximal end and MISLH distal end, and the MISLH may include an optical coupler located at the MISLH proximal end, a substantially straight central bore within the MISLH, and an internal beam stop aperture within the central bore adjoined to the optical coupler. The central bore may extend from the optical coupler to the MISLH distal end and the central bore may be configured to accept the insertion of the probe within the central bore at the MISLH distal end. Additionally, the central bore may be configured to accept the insertion of the probe such that the probe is adjoined to the internal beam stop aperture. | 09-15-2011 |
20120257167 | GONIOSCOPE FOR IMPROVED VIEWING - Various embodiments relate to ophthalmoscopic devices, systems and methods for viewing the anterior chamber, trabecular meshwork, iris root, scleral spur, and/or related nearby structures in the eye. In some embodiments, devices, systems and/or methods may employ a plurality of gonioscopic optical elements that form a virtual image that can be imaged by a microscope directly in front of a patient (e.g., without tilting the patient's head). Various embodiments described herein may be useful for ophthalmologic diagnoses, treatments, monitoring and/or surgical procedures. Some embodiments include a gonioscopic attachment configured to attach to a conventional gonioscope and redirect light emitted by the gonioscope. Various embodiments described herein can be incorporated into disposable, single-use gonioscopes. Some embodiments include a gonioscopic optical element that is movable with respect to another gonioscopic optical element. Some embodiments include a gonioscopic instrument that is attached to a microscope. | 10-11-2012 |
20120265077 | Component-Based Catheter Lab Intravascular Ultrasound System - A componentized intravascular ultrasound system is disclosed that flexibly integrates with a catheter lab infrastructure for acquisition and display of intravascular information in a catheter lab environment. The system includes a patient interface module (PIM) adapted to hold a catheter having an imaging probe located near a distal end, a control panel, a monitor for displaying images and patient data, and a processing unit. The processing unit is communicatively coupled to the PIM, the control panel, and the monitor. Furthermore the processing unit adapted to: coordinate operation of the PIM, the control panel, and the monitor; and generate images from image data provides by the PIM. The PIM, control panel and monitor are independently positionable with regard to one another. | 10-18-2012 |
20150038893 | SYSTEM FOR DELIVERING MULTIPLE OCULAR IMPLANTS - Systems and methods for delivering multiple ocular implants to reduce intraocular pressure are disclosed. The ocular implants can be implanted at multiple sites within a single human eye without requiring removal of the delivery apparatus from the eye. A system for delivering multiple ocular implants can include at least two implants preloaded within a delivery device and configured to be implanted within the eye, a metering device configured to transfer energy to the implants for delivery at selected locations within the eye, wherein the metering device is configured to meter a variable amount of energy for each implant delivery event in the eye. The system can further include an injector mechanism configured to serially engage and drive each of the implants. | 02-05-2015 |
Patent application number | Description | Published |
20120098847 | SYSTEM AND METHOD FOR REDUCED RESOLUTION ADDRESSING - This disclosure provides systems, methods and apparatus including computer programs encoded on computer storage media for producing line multiplied images with better visual appearance. The line multiplying is shifted for one of the colors of the display with respect to at least one other color of the display. | 04-26-2012 |
20130100096 | DEVICE AND METHOD OF CONTROLLING BRIGHTNESS OF A DISPLAY BASED ON AMBIENT LIGHTING CONDITIONS - This disclosure provides systems, methods and apparatus, including computer programs encoded on computer storage media, for controlling brightness of a display based on ambient light conditions. In one aspect, a display device can include a reflective display and an auxiliary light source configured to provide supplemental light to the display. The display device further can include a sensor system configured to determine an illuminance of ambient light, and a controller configured to adjust the auxiliary light source to provide an amount of supplemental light to the display based at least in part on the determined illuminance. In one aspect, the amount of supplemental light remains substantially the same or substantially increases in response to increasing illuminance when the illuminance is below a first threshold, and substantially decreases in response to increasing illuminance when the illuminance is above a second threshold that is greater than or equal to the first threshold. | 04-25-2013 |
20130135338 | METHOD AND SYSTEM FOR SUBPIXEL-LEVEL IMAGE MULTITONING - This disclosure provides systems, methods and apparatus, including computer programs encoded on computer storage media, for displaying high resolution images using examples of a halftoning method based on diffusing quantization error from a subpixel displaying a color to one or more subpixels that display a different color. | 05-30-2013 |
20130182017 | DEVICE AND METHOD FOR HIGH REFLECTANCE MULTI-STATE ARCHITECTURES - This disclosure provides systems, methods and apparatus for device and methods for high reflectance multi-state architectures. In one aspect, a display device can include a plurality of reflective pixels including subpixels. Each subpixel can be selectively switched among first, second, and third states, with each state having a different spectral reflectance. Each subpixel has a spectral reflectance associated with a first set of primary colors and with a second set of primary colors. At least one of the colors in the second set of primary colors can be different from the colors in the first set of primary colors. The first set of primary colors can include colors that combine to produce white. A combination of colors of the first set of primary colors can have a brightness that is higher than the brightness of the combination of colors of the second set of primary colors. | 07-18-2013 |
20130249936 | MULTI-LEVEL STOCHASTIC DITHERING WITH NOISE MITIGATION VIA SEQUENTIAL TEMPLATE AVERAGING - Displays, and methods of displaying images with the displays, which have quantized display characteristics for each of the pixels are disclosed. The displays and methods relate to both spatially and temporally dithering images so that the effective resolution of the display is higher than the result of the native spatial and intensity resolutions of the display, defined by pixel size, pitch, and number of quantization levels of each of the pixels. | 09-26-2013 |
Patent application number | Description | Published |
20080266333 | HYBRID COLOR SYNTHESIS FOR MULTISTATE REFLECTIVE MODULAR DISPLAYS - A display device including a plurality of optical modulators and a plurality of filter elements on a reflective side of the plurality of optical modulators is provided. The plurality of optical modulators includes a first set of optical modulators and a second set of optical modulators. Each optical modulator of the plurality of optical modulators is configured to be selectively switched among at least a first state, a second state, and a third state. Each state has a different spectral reflectance. The plurality of filter elements includes a first set of filter elements corresponding to the first set of optical modulators and a second set of filter elements corresponding to the second set of optical modulators. The first set of filter elements has a different spectral transmittance than the second set of filter elements. | 10-30-2008 |
20090201318 | MULTI-LEVEL STOCHASTIC DITHERING WITH NOISE MITIGATION VIA SEQUENTIAL TEMPLATE AVERAGING - Displays, and methods of displaying images with the displays, which have quantized display characteristics for each of the pixels are disclosed. The displays and methods relate to both spatially and temporally dithering images so that the effective resolution of the display is higher than the result of the native spatial and intensity resolutions of the display, defined by pixel size, pitch, and number of quantization levels of each of the pixels. | 08-13-2009 |
20120236021 | METHODS AND APPARATUS FOR DITHER SELECTION - Systems, methods and apparatus including computer programs encoded on computer storage media optimize display image quality under a variety of imaging environments. Dynamic frame streams such as those present in video applications may require a higher frame rate to adequately convey motion in the stream. A line multiplying image pipeline may be utilized for dynamic frames, which lowers the resolution of the displayed image. When dithering line multiplied images, a noise signal including asymmetrical high frequency components around zero frequency may be utilized. The display of static frames, such as photographs, may be achieved with acceptable image quality using a relatively lower display frame rate. Such a frame rate may enable the display of a high resolution image. A noise signal tailored for higher resolution, non line multiplied frames, such as a noise signal with symmetric high frequency components around zero frequency may be utilized for static frames. | 09-20-2012 |
20120268479 | METHODS AND APPARATUS FOR IMPROVED DITHERING ON A LINE MULTIPLIED DISPLAY - This disclosure provides systems, methods and apparatus including computer programs encoded on computer storage media for producing line multiplied images with better visual appearance. In one aspect, before lines of the image are multiplied, they are dithered with a noise signal that increases faster with higher frequency along the multiplied dimension of the image data than along the non multiplied dimension of the image. This results in a line multiplied image was improved image quality. | 10-25-2012 |
20130046803 | DITHER-AWARE IMAGE CODING - This disclosure provides implementations of dither-aware image coding processes, devices, apparatus, and systems. In one aspect, a portion of received image data is selected. First spatial domain values in the selected portion of the image data are transformed to first transform domain coefficients. Second spatial domain values in a designated dither matrix are transformed to second transform domain coefficients. A ratio of each of the first transform domain coefficients to a respective second transform domain coefficient is determined. The first transform domain coefficients are selectively coded in accordance with the determined ratios to define coded first transform domain coefficients. A reverse transformation is performed to transform the coded first transform domain coefficients to third spatial domain values defining a coded portion of the image data. By way of example, transformations such as discreet cosine transforms or discreet wavelet transforms can be used. | 02-21-2013 |
20130069968 | METHODS AND APPARATUS FOR HYBRID HALFTONING OF AN IMAGE - This disclosure provides methods, apparatus, and computer programs encoded on computer storage media for tone based halftoning of digital images. By exploiting knowledge of local image features and tone levels, the halftoning method may be adaptively switched between error-diffusion and mask-based dithering with reduced boundary artifacts. By further utilizing a smart quantization error clipping scheme, artifacts inherent to the method of error diffusion are also reduced. The method consistently generates higher quality halftone images for both still and video applications when compared to conventional methods. | 03-21-2013 |
20130069974 | HYBRID VIDEO HALFTONING TECHNIQUES - This disclosure provides techniques related to halftoning video images for display on an electronic device. The techniques include adaptively selecting, on a pixel-by-pixel basis, between a mask-based dithering (MBD) and an error diffusion (ED) halftoning technique. The ED technique may be selected for halftoning pixels of an input frame of data having either a temporal change rate metric (CRM) or a spatial CRM exceeding a respective threshold. Where both the temporal CRM and spatial CRM are less than the respective thresholds, halftoning may be performed by the technique that produces a halftone value closer to a comparison halftone value of a comparison frame. The comparison frame may be a preceding frame, or an immediately preceding frame. | 03-21-2013 |
20140160137 | FIELD-SEQUENTIAL COLOR MODE TRANSITIONS - This disclosure provides systems, methods and apparatus, including computer programs encoded on computer storage media, for selecting an operational mode of a reflective display device from a plurality of operational modes that include at least one field-sequential color mode. The operational mode may be selected based, at least in part, on ambient light data. The ambient light data may include ambient light intensity data, ambient light spectrum data and/or ambient light direction data. The operational mode may be selected based, at least in part, on other criteria, such as display application type and/or battery state data. | 06-12-2014 |
20150310794 | GRAPHICAL ELEMENTS FOR WHITE-POINT CALIBRATION AND ADJUSTMENT TECHNIQUES FOR DISPLAYS - This disclosure describes techniques for calibrating and adjusting the white point of a display. The techniques for calibrating and adjusting the white point of a display may receive data indicative of a target color temperature for a white point of a display, and provide one or more user interface components that allow a user to select between multiple different candidate white points where each of the of the candidate white points has a correlated color temperature that corresponds to the target color temperature Different target white points for a display may exhibit different levels of luminance loss and/or tint. The techniques for calibrating and adjusting the white point of a display may allow a user to evaluate the trade-off between the luminance loss characteristics and/or tint characteristics of different white points. | 10-29-2015 |
20150346987 | DISPLAY MODE SELECTION ACCORDING TO A USER PROFILE OR A HIERARCHY OF CRITERIA - Some implementations provide automatic display mode selection for a device, such as a mobile display device, according to a hierarchy of criteria. Each display mode may correspond with a set of display parameter settings, which may include a color depth setting, a brightness setting, etc. In some examples, one of the criteria may correspond with a software application being executed on the device. Some implementations involve creating a display device user profile and controlling a display of a mobile display device according to the user profile. The user profile may be built gradually over some number of days/weeks/months after the first use of the device. In some implementations, display parameter setting information or other device setting information corresponding to data in a user profile, including but not limited to demographic data, may be received by a mobile display device from another device, such as a server. | 12-03-2015 |
Patent application number | Description | Published |
20140049653 | Authentication and Validation of Smartphone Imagery - A method, system, and processor-executable software for processing images or video captured by a smartphone or other digital image capture device for subsequent validation and authentication captures not only the image, but also metadata relevant to the authenticity of validity of the image, such as position, time, camera movement and orientation, image parameters, and so forth. The image is watermarked and both the watermarked image and the metadata, as well as a symmetric key used in the watermarking, are digitally signed and transmitted or uploaded to a web server or authentication centric entity for authentication and storage. When a third party submits an image to the web server or authentication centric entity, the submitted image is compared with the stored watermarked image for authentication and validation of the submitted image, and the metadata is then retrieved to enable analysis of the contents of authenticated and validated image. | 02-20-2014 |
20160070892 | SYSTEM AND METHOD FOR CREATING, PROCESSING, AND DISTRIBUTING IMAGES THAT SERVE AS PORTALS ENABLING COMMUNICATION WITH PERSONS WHO HAVE INTERACTED WITH THE IMAGES - A system and method for processing, storage, distribution, and interaction with electronic images created or captured by mobile devices having network communications capabilities, such as smartphones, allows a user whose image-displaying device includes enhanced viewer software to use an image displayed on the image-displaying device as a portal for communication with others who have interacted with the image, including authors and facilitators of the image. Watermarking and security measures are provided to enable source and content verification of a displayed image so that user morphing of imagery can be tracked to maintain stability of image-based interaction and so that malicious imagery tamper can be prevented. | 03-10-2016 |