Patent application number | Description | Published |
20100197937 | NOVEL COMPOUND, PROBE CONTAINING THE NOVEL COMPOUND, AND FLUORESCENCE-IMAGING CONTRAST AGENT CONTAINING THE NOVEL COMPOUND OR THE PROBE - A compound represented by Formula (1) below, | 08-05-2010 |
20130095038 | PARTICLES, AND PHOTOACOUSTIC IMAGING CONTRAST AGENT AND SLN CONTRAST AGENT INCLUDING THE PARTICLES - Provided are particles where a hydrophilic coloring agent having an anionic functional group, such as ICG, hardly leaks from the particles. The particles include a coloring agent having an anionic functional group, such as ICG, ions of a polyvalent metal, such as iron ions (Fe | 04-18-2013 |
20130224121 | PARTICLE CONTAINING HYDROPHOBIC DYE HAVING CYANINE STRUCTURE, AND CONTRAST AGENT CONTAINING THE PARTICLE - Provided is a particle which can stably hold a dye in itself even in an aqueous solution such as serum, in order to solve such a problem of a particle containing ICG, which has been conventionally used in a contrast agent or the like, that the ICG is a dye having a hydrophilic functional group and hence the ICG leaks out of the particle in an aqueous solution such as serum. More specifically, provided is a particle including a hydrophobic dye having a cyanine structure, in which the hydrophobic dye is represented by the following chemical formula (1). | 08-29-2013 |
20130243694 | PARTICLES AND CONTRAST AGENT INCLUDING THE SAME FOR OPTICAL IMAGING - A particle includes a copolymer of lactic acid and glycolic acid, and at least one compound selected from silicon naphthalocyanine and derivatives of silicon naphthalocyanine, in which the particle has a particle size of 10 nm or more and less than 1000 nm. | 09-19-2013 |
20130315837 | DYE-CONTAINING NANOPARTICLE FOR PHOTOACOUSTIC CONTRAST AGENT - An object of the present invention is to increase the dye content in nanoparticles and to improve the signal intensity per particle. According to the nanoparticle including at least a silicon naphthalocyanine or a derivative thereof and a surfactant, wherein the proportion of the silicon naphthalocyanine or the derivative thereof is 70% or more by weight in relation to the other component of the particle exclusive of the surfactant, the dye content in the nanoparticles can be increased and the signal intensity per particle can be improved without weakening the signal intensity per dye molecule (light absorptivity) | 11-28-2013 |
20140377180 | PHOTOACOUSTIC CONTRAST AGENT HAVING LIPID PARTICLE CONTAINING SILICON NAPHTHALOCYANINE ANALOG - A conventional silicon naphthalocyanine-containing liposome is required to incorporate a dye dispersed therein for use in photodynamic therapy, and is thus low in dye content and also low in photoacoustic signal. According to a lipid particle containing a silicon naphthalocyanine analog, in which the ratio A/B of an absorption coefficient A at a first absorption local maximum to an absorption coefficient B at a second absorption local maximum in a range from 700 nm to 800 nm is 5.0 or less, the dye content in the lipid particle can be increased and the photoacoustic signal intensity can be improved. | 12-25-2014 |
20150037254 | CONTRAST AGENT FOR PHOTOACOUSTIC IMAGING - Provided is a particle having a large photoacoustic signal per unit dye, the particle including: one of a hydrophobic metal naphthalocyanine dye and a hydrophobic metal phthalocyanine dye; one of an oil, a fatty acid, and a fatty acid ester as a matrix material; and a surfactant, in which a ratio of the weight of the matrix material to the weight of the particle is 50% or more. | 02-05-2015 |
20150037255 | PHTHALOCYANINE DYE-CONTAINING CONTRAST AGENT FOR PHOTOACOUSTIC IMAGING - To provide a particle promoting hydrophobic metal phthalocyanine aggregation, having absorption in a wavelength region suitable for a photoacoustic imaging method and having a high molar absorbance coefficient per particle by increasing the weight percentage of the dye in the particle. The particle of the present invention is a particle having a hydrophobic metal phthalocyanine and a surfactant, wherein the weight percentage of the hydrophobic metal phthalocyanine is 6% or more. | 02-05-2015 |