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| 20090097414 | COMMUNICATION DEVICE AND METHOD OF PROVIDING LOCATION INFORMATION THEREIN - A communication device, computer program product and method of providing location information therein are disclosed. The communication device includes a wireless communication unit configured to receive location information concerning the communication device, a display, a memory and a controller operatively connected to the wireless communication unit, the display and the memory, the controller configured to periodically store, in the memory, a current location and a current time of the communication device and generate a movement history of the communication device using the periodically stored current location and current time. | 04-16-2009 |
| 20130072459 | PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR THE TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE AND THE METHOD FOR PREVENTION OR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE USING THE SAME - The present invention provides a pharmaceutical composition for the prevention and treatment of a non-alcoholic fatty liver disease (NAFLD), containing an active ingredient selected from the group consisting of Compound 1 represented by formula 1, sitagliptin, vildagliptin, linagliptin or a pharmaceutically acceptable salt thereof. Further, the present invention provides a method for the prevention or treatment of a non-alcoholic fatty liver disease, including administering an effective amount of an active ingredient selected from the group consisting of Compound 1 represented by formula 1, sitagliptin, vildagliptin, linagliptin or a pharmaceutically acceptable salt thereof to a mammal including a human in need thereof. Further, the present invention provides use of Compound 1 represented by formula 1, sitagliptin, vildagliptin, linagliptin or a pharmaceutically acceptable salt thereof, for manufacturing a pharmaceutical composition for the prevention or treatment of a non-alcoholic fatty liver disease. | 03-21-2013 |
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| 20090075707 | PORTABLE SLIDE TERMINAL OPENED IN A BAR SHAPE - A portable terminal is provided, in which there is a first housing, a second housing is slidably engaged with the first housing, facing the first housing, and a connection member has one part slidably engaged with the first housing and another part slidably engaged with the second housing. The second housing slides to open or close a surface of the first housing with the guidance of the connection member and when the second housing is upright on a top end of the first housing, the second housing is selectively engaged with the first housing. | 03-19-2009 |
| 20100178939 | METHOD OF PROVIDING LOCATION-BASED SERVICE USING LOCATION INFORMATION OF MOBILE TERMINAL - Disclosed is a location-based service method using location information of a mobile terminal in a mobile communication system. In a location-based service providing method, second mobile terminals within a predetermined range of a first mobile terminal are searched for, status information and relative location information of one or more second mobile terminals found is collected, and display data comprising the relative locations and status information of the one or more second mobile terminals found is sent to the first mobile terminal. | 07-15-2010 |
| 20100295113 | SEMICONDUCTOR DEVICES COMPRISING A PLURALITY OF GATE STRUCTURES - Semiconductor devices including a plurality of gate structures disposed on a semiconductor substrate are provided. Each of the gate structures includes a tunnel dielectric layer, a floating gate, an inter-gate dielectric layer, a control gate, and a mask layer. Liners cover opposing sidewalls of adjacent floating gates. Spacers are disposed on the liners, the spacers protruding from opposing sidewalls of adjacent ones of the gate structures, and a top of each of the spacers is disposed below a top of a corresponding one of the gate structures. The liners define sidewalls of respective air gaps and the spacers define tops of the respective air gaps. | 11-25-2010 |
| 20110000704 | Printed Circuit Board and Method of Manufacturing the Same - Provided is a method of manufacturing a printed circuit board including, disposing first and second insulating members and first and second conductive films on both sides of a separating member to perform a thermocompression bonding process on the first and second insulating members and the first and second conductive films on the both sides of the separating member, so as to attach the first member to the second member with the separating member therebetween and attach the first insulating member to the first conductive film and attach the second insulating member to the second conductive film, selectively removing the first and second conductive films to form first and second circuit patterns, and cutting the separating member and the first and second insulating members to separate the first and second insulating members with the first and second circuit patterns from the separating member. | 01-06-2011 |
| 20110121455 | Semiconductor Devices Having Interconnection Structures - An interconnection structure for a semiconductor device may include lower interconnection patterns disposed in a checker board shape and upper interconnection patterns disposed in a checker board shape and connecting two adjacent lower interconnection patterns to each other. | 05-26-2011 |
| 20110163367 | Semiconductor Devices Comprising a Plurality of Gate Structures - Semiconductor devices are provided. The semiconductor devices may include a plurality of gate structures disposed on a semiconductor substrate, each of the gate structures including a floating gate, an inter-gate dielectric layer, and a control gate. The semiconductor devices may also include liners on opposing sidewalls of adjacent ones of the gate structures. The liners may define a gap. A first width of the gap may be less than a second width of the gap. | 07-07-2011 |
| 20130178044 | SEMICONDUCTOR DEVICES COMPRISING A PLURALITY OF GATE STRUCTURES - Methods for forming semiconductor memory structures including a gap between adjacent gate structures are provided. The methods may include forming an insulation layer between the adjacent gate structures. In some embodiments, the methods may include subsequently removing a portion of the insulation layer to leave the gap between the adjacent gate structures. | 07-11-2013 |
| 20140134319 | PROCESSED MEAT PRODUCT WITHOUT ADDED PHOSPHATE, AND METHOD OF PRODUCING SAME - The present invention relates to a processed meat product (sausage and ham) having no added phosphate, which is a harmful ingredient to humans and is used in processes for producing processed meat products, and to a method for producing same. According to the present invention, the pH of ground raw meat is raised to increase the water retention thereof, and a basic pH control agent, alone or combined with a hydrocolloid, is used as a substituting means for phosphate in order to improve syneresis and texture. According to the present invention, a processed meat product having added phosphate may be provided having improved quality without including phosphate. | 05-15-2014 |
| 20140134601 | USE OF PROTEIN NANOPARTICLE BASED HYDROGEL - The present invention relates to a use of a protein nanoparticle-based hydrogel, and more particularly, to a use of a protein nanoparticle-based hydrogel capable of highly sensitive and simultaneous multi-detection of disease markers by using a hydrogel to which a protein nanoparticle representing a disease marker detection probe is immobilized. | 05-15-2014 |
| 20140234521 | LOW FAT MAYONNAISE COMPOSITION AND METHOD OF PRODUCING THE SAME - Provided are a low fat mayonnaise composition to which cellulose ether is applied, and a method of producing the same, in which the low fat mayonnaise composition includes 50 wt % or less of an emulsion with respect to the total weight of the composition, and cellulose ether and an excipient as a fat substitute. Therefore, with the mayonnaise composition, low fat mayonnaise which includes an oil and fat content of ½ or less may be produced from only a vegetable material having phase stability at various temperatures without using eggs which may lead to an allergy and may serve as a primary source of increasing cholesterol. | 08-21-2014 |
| 20140358287 | REFRIGERATOR AND METHOD FOR CONTROLLING THE SAME - A refrigerator includes a communication unit to receive a list of food purchased by a user from a food server; a control unit to read information with respect to food on the received list of food, and identify a representative image that represents the food based on the read information; a display unit to display the received list of food such that the food on the list of food is displayed as the representative image that represents the food; and a storage unit to store the read information. Accordingly, a design effect is enhanced by expressing the information of the purchased food as a representative image and by displaying additional information of the representative image. In addition, the information with respect to the purchased food is easily stored at a refrigerator, and the information with respect to new products is easily and quickly obtained, thus a user convenience is enhanced. | 12-04-2014 |
| 20150110925 | LOW-CALORIE BEVERAGE COMPOSITION - Disclosed is a beverage composition. The beverage composition includes a sweetener and cellulose ether. Accordingly, the beverage composition provides a strong sweet taste with low levels of unpleasant tastes or residual tastes, and satisfactory body-viscosity. | 04-23-2015 |
| 20150236271 | NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME - The present invention relates to a novel compound and an organic electroluminescence device including the same, and the compound according to the present invention may be used in an organic material layer, preferably a light-emitting layer of an organic electroluminescence device, thereby enhancing the light-emitting efficiency, driving voltage, lifespan, and the like of the organic electroluminescence device. | 08-20-2015 |
| 20150272150 | FERMENTED MILK COMPOSITION CONTAINING CELLULOSE ETHER AND PRODUCTION METHOD THEREOF - The present invention relates to a fermented milk composition containing cellulose ether and a production method thereof, the fermented milk composition includes cellulose ether as a stabilizer for preventing a whey separation phenomenon, and the production method of fermented milk includes manufacturing a fermented base; manufacturing a cellulose ether syrup; and adding the cellulose ether syrup to the fermented base to perform homogenization and cooling. As described above, in the fermented milk composition, it is possible to provide a fermented milk beverage securing stabilized phase stability and having reduced sourness by applying cellulose ether in a small amount instead of pectin as the stabilizer for preventing the whey separation phenomenon. | 10-01-2015 |
| 20150313244 | RICE DOUGH COMPOSITION, AND RICE DOUGH PREPARED THEREFROM - Provided is a rice dough composition and a rice dough prepared therefrom. The rice dough composition includes rice flour, cellulose ether, gums, and emulsifier. The rice dough composition may be used to prepare a rice dough that may be eaten by people sensitive to gluten and has a mouthfeel different from a rice dough obtained from wheat flour. When the rice dough is re-cooked by heating after being stored in a frozen state, evaporation of water is inhibited and mouthfeel changes due to a hardening phenomenon may be reduced. | 11-05-2015 |
| 20150318483 | NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME - The present disclosure relates to a novel compound having excellent hole injection capabilities and transport capabilities, light-emitting capabilities, and the like, and an organic electroluminescent device which includes the compound in one or more organic material layers thereof so as to improve characteristics such as light-emitting efficiency, driving voltage, and a service life. | 11-05-2015 |
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| 20120168968 | EPOXY RESIN COMPOSITION FOR ENCAPSULATING A SEMICONDUCTOR DEVICE, METHOD OF ENCAPSULATING A SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE - An epoxy resin composition for encapsulating a semiconductor device, a method of encapsulating a semiconductor device, and a semiconductor device, the composition including an epoxy resin; a curing agent; a curing accelerator; an inorganic filler; and a flame retardant; wherein the flame retardant includes boehmite, and is present in an amount of about 0.1 to 20% by weight (wt %), based on a total weight of the epoxy resin composition. | 07-05-2012 |
| 20120302667 | EPOXY RESIN COMPOSITION FOR ENCAPSULATING SEMICONDUCTOR DEVICE AND SEMICONDUCTOR DEVICE ENCAPSULATED WITH THE SAME - An epoxy resin composition for encapsulating a semiconductor device includes a curing agent, a curing accelerator, inorganic fillers, and an epoxy resin, the epoxy resin including a first resin represented by Formula 1: | 11-29-2012 |
| 20140179833 | EPOXY RESIN COMPOSITION FOR ENCAPSULATION OF SEMICONDUCTOR DEVICE AND SEMICONDUCTOR DEVICE ENCAPSULATED USING THE SAME - A epoxy resin composition includes an epoxy resin including repeat units represented by Formulae 1 and 2; a curing agent; a curing accelerator; and an inorganic filler, | 06-26-2014 |
| 20140179834 | EPOXY RESIN COMPOSITION FOR ENCAPSULATION OF SEMICONDUCTOR DEVICE AND SEMICONDUCTOR DEVICE ENCAPSULATED USING THE SAME - An epoxy resin composition includes an epoxy resin including repeat units represented by Formulae 1 and 2; a curing agent; a curing accelerator; and an inorganic filler, | 06-26-2014 |
| 20160093547 | EPOXY RESIN COMPOSITION FOR ENCAPSULATING SEMICONDUCTOR DEVICE AND SEMICONDUCTOR PACKAGE ENCAPSULATED USING THE SAME - An epoxy resin composition for encapsulating a semiconductor device and a semiconductor package, the composition including an epoxy resin; a polyorganosiloxane resin represented by Formula 3, below; a curing agent; a curing accelerator; and an inorganic filler: | 03-31-2016 |
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| 20100270571 | SLIM LED PACKAGE - Disclosed herein is a slim LED package. The slim LED package includes first and second lead frames separated from each other, a chip mounting recess formed on one upper surface region of the first lead frame by reducing a thickness of the one upper surface region below other upper surface regions of the first lead frame, an LED chip mounted on a bottom surface of the chip mounting recess and connected with the second lead frame via a bonding wire, and a transparent encapsulation material protecting the LED chip while supporting the first and second lead frames. | 10-28-2010 |
| 20110108866 | LED PACKAGE AND METHOD FOR FABRICATING THE SAME - An LED package is disclosed herein. The disclosed LED package comprises a base having an LED chip mounted thereon, an encapsulation member formed by a light-transmittable resin to encapsulate the LED chip, and a housing formed to expose a top portion of the encapsulation member and to encompass a side surface of the encapsulation member, wherein the encapsulation member is formed by a transfer molding process using a mold to have a predetermined shape. Further, the housing may be light-transmittable. | 05-12-2011 |
| 20130020604 | SLIM LED PACKAGE - Disclosed herein is a slim LED package. The slim LED package includes first and second lead frames separated from each other, a chip mounting recess formed on one upper surface region of the first lead frame by reducing a thickness of the one upper surface region below other upper surface regions of the first lead frame, an LED chip mounted on a bottom surface of the chip mounting recess and connected with the second lead frame via a bonding wire, and a transparent encapsulation material protecting the LED chip while supporting the first and second lead frames. | 01-24-2013 |
| 20140110739 | LED PACKAGE AND METHOD FOR FABRICATING THE SAME - A light emitting diode (LED) package according to an exemplary embodiment of the present invention includes a base including a first lead terminal and a second lead terminal, an LED chip disposed on the base, a housing disposed on the base, the housing having a cavity in which the LED chip is disposed, and an encapsulation member having a side surface contacting the housing. The first lead terminal and the second lead terminal each have a first surface and a second surface opposite the first surface, and have an unbent form, respectively. The second surface is exposed to the outside of the LED package. | 04-24-2014 |
| 20140131762 | SLIM LED PACKAGE - Disclosed herein is a slim LED package. The slim LED package includes first and second lead frames separated from each other, a chip mounting recess formed on one upper surface region of the first lead frame by reducing a thickness of the one upper surface region below other upper surface regions of the first lead frame, an LED chip mounted on a bottom surface of the chip mounting recess and connected with the second lead frame via a bonding wire, and a transparent encapsulation material protecting the LED chip while supporting the first and second lead frames. | 05-15-2014 |
| 20140306257 | LED PACKAGE AND METHOD FOR FABRICATING THE SAME - A light emitting diode (LED) package according to an exemplary embodiment of the present invention includes a base including a first lead terminal and a second lead terminal, an LED chip disposed on the base, a housing disposed on the base, the housing having a cavity in which the LED chip is disposed, and an encapsulation member having a side surface contacting the housing. The first lead terminal and the second lead terminal each have a first surface and a second surface opposite the first surface, and have an unbent form, respectively. The second surface is exposed to the outside of the LED package. | 10-16-2014 |
| 20140374788 | LIGHT EMITTING DEVICE - Provided is a light emitting device. The light emitting device includes: a plurality of lead frame units spaced apart from each other, each of the lead frame units being provided with at least one fixing space perforating a body thereof in a vertical direction; a light emitting diode chip mounted on one of the lead frame units; and a molding unit that is integrally formed on top surfaces of the lead frame units and in the fixing spaces to protect the light emitting diode chip. | 12-25-2014 |
| 20150162514 | SLIM LED PACKAGE - Disclosed herein is a slim LED package. The slim LED package includes first and second lead frames separated from each other, a chip mounting recess formed on one upper surface region of the first lead frame by reducing a thickness of the one upper surface region below other upper surface regions of the first lead frame, an LED chip mounted on a bottom surface of the chip mounting recess and connected with the second lead frame via a bonding wire, and a transparent encapsulation material protecting the LED chip while supporting the first and second lead frames. | 06-11-2015 |
| 20150340570 | SLIM LED PACKAGE - Disclosed herein is a slim LED package. The slim LED package includes first and second lead frames separated from each other, a chip mounting recess formed on one upper surface region of the first lead frame by reducing a thickness of the one upper surface region below other upper surface regions of the first lead frame, an LED chip mounted on a bottom surface of the chip mounting recess and connected with the second lead frame via a bonding wire, and a transparent encapsulation material protecting the LED chip while supporting the first and second lead frames. | 11-26-2015 |
| 20160072032 | LIGHT EMITTING DEVICE - A light-emitting device includes first and second lead frames spaced apart from each other, the first and second lead frames each comprising a top surface, an opposing bottom surface, and sidewalls arranged between the top surface and the bottom surface thereof, at least one of the first and second lead frames comprise three inset sidewalls that at least partially define a fixing space, the fixing space undercutting at least one of the first lead frame and second lead frame, a light-emitting diode chip arranged on the first surface of the first or second lead frame, a resin part disposed in the fixing space to support the first and second lead frames, and the first and second lead frames exposed to the outside through bottom surface. | 03-10-2016 |
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| 20120004372 | ACRYL-BASED COPOLYMERS AND OPTICAL FILM INCLUDING THE SAME - The present invention relates to acryl-based copolymers including an alkyl(meth)acrylate-based monomer; a (meth)acrylate-based monomer containing an aromatic ring; and a maleimide-based monomer, a resin composition including the same, and an optical film prepared by using the same. | 01-05-2012 |
| 20130144023 | ACRYLIC COPOLYMER WITH HIGH HEAT RESISTANCE AND HIGH STRENGTH, AND OPTICAL FILM COMPRISING THE SAME - The present invention relates to an acrylic copolymer having high heat resistance and high strength, and an optical film comprising the same, and more particularly, to an acrylic copolymer for optical films in which alkyl (meth)acrylate monomers; (meth)acrylate monomers comprising aromatic rings and/or aliphatic rings; and (meth)acrylamide monomers are included and polymerized. An acrylic copolymer according to the present invention is excellent in heat resistance while maintaining transparency. Further, an optical film comprising a compound resin including the acrylic copolymer has superior transparency and heat resistance and is excellent in formability, adhesion, retardation properties, and durability. | 06-06-2013 |
| 20130150546 | HIGHLY HEAT RESISTANT AND HIGHLY STRONG ACRYLIC COPOLYMER, A RESIN COMPOSITION COMPRISING THE SAME AND AN OPTICAL FILM AND AN IPS MODE LIQUID CRYSTAL DISPLAY DEVICE COMPRISING THE SAME - Provided is an acrylic copolymer comprising; an alkyl (meth)acrylate monomer; a monomer comprising a cyclic pendant structure; and a tert-butyl (meth)acrylate monomer and/or (meth)acrylamide monomer. Also provided is a resin composition comprising the same and an optical film and an IPS mode liquid crystal display device using the same. | 06-13-2013 |
| 20130190451 | RESIN COMPOSITION FOR OPTICAL FILM, AND POLARIZER PROTECTIVE FILM AND LIQUID CRYSTAL DISPLAY INCLUDING THE SAME - Provided are a resin composition including an acryl-based copolymer resin including an alkyl(meth)acrylate-based monomer and an imide-based monomer, additionally copolymerizable with a styrene-based monomer, and a polycarbonate-based resin having a melt index (MI) of 30 g/10 min or more under conditions of a load of 1.2 kg and a temperature of 300° C., a polarizer protective film including the resin composition, and a liquid crystal display including the polarizer protective film. The polarizer protective film according to the present invention has excellent heat resistance, transparency, and optical properties. | 07-25-2013 |
| 20130314785 | RESIN COMPOSITION AND OPTICAL FILM FORMED BY USING THE SAME - Provided are a resin composition and an optical film formed by using the same, and more particularly, a resin composition including 85 to 95 parts by weight of a matrix copolymer resin including an alkyl(meth)acrylate-based unit, an acryl-based unit containing a benzene ring, and a (meth)acrylic acid unit, and 5 to 15 parts by weight of a polymer resin having a molecular weight range of 150,000 to 1,000,000 and an optical film formed by using the composition. A resin composition according to the present invention may provide a protective film for a polarizing plate having excellent heat resistance and toughness as well as excellent optical properties, and thus, an optical film formed by using the resin composition of the present invention may be used in information electronic devices such as display devices for various applications. | 11-28-2013 |
| 20140015152 | METHOD FOR PREPARING ACRYLIC COPOLYMER RESIN FOR OPTICAL FILM AND METHOD FOR FABRICATING OPTICAL FILM USING THE SAME - There is provided a method for preparing an acrylic copolymer resin for an optical film includes: suspension-polymerizing an acrylic monomer containing a benzene ring, an alkyl(meth)acrylate monomer, and a (meth)acrylic acid monomer to prepare a copolymer; and thermally treating the copolymer at a temperature ranging from 240° C. to 300° C. As the method for preparing an acrylic copolymer of the present invention, a resin having an effectively lowered CTE can be manufactured by inducing the formation of a glutaric anhydride structure by using suspension polymerization that facilitates adjustment of the molecular weight of a resin. | 01-16-2014 |
| 20140036363 | RESIN COMPOSITION FOR OPTICAL FILM AND OPTICAL FILM USING THE SAME - Provided are a resin composition for an optical film including an alkyl(meth)acrylate unit, a benzyl(meth)acrylate unit, a (meth)acrylic acid unit, and a unit expressed by Chemical Formula I, an optical film, a polarizing plate, and an image display device using the resin composition. | 02-06-2014 |
| 20160108224 | HEAT-RESISTANT SAN RESIN, METHOD FOR MANUFACTURING SAME, AND HEAT-RESISTANT ABS RESIN COMPOSITION COMPRISING SAME - Disclosed are a heat-resistant SAN resin, a method of preparing the same, and a heat-resistant ABS resin composition comprising the same. More particularly, a heat-resistant SAN resin comprising 60 to 75 wt % of α-methylstyrene, 25 to 35 wt % of a vinyl cyan compound, and 0 to 10 wt % of an aromatic vinyl compound (except for α-methylstyrene), the heat-resistant SAN resin having a degree of branching of 0.40 to 0.60, a molecular weight of 90,000 to 150,000 g/mol, and a glass transition temperature (Tg) of 124 to 140° C., a method of preparing the same, and a heat-resistant ABS resin composition comprising the same are disclosed. | 04-21-2016 |
| 20160115309 | (METH)ACRYLATE-BASED RESIN COMPOSITION HAVING EXCELLENT IMPACT RESISTANCE AND TRANSPARENCY - Disclosed is a (meth)acrylate-based resin composition comprising a poly(alkyl(meth)acrylate-phenyl(meth)acrylate) copolymer comprising phenyl(meth)acrylate having excellent surface hardness and a high refractive index, as a base resin and a (conjugated diene (meth)acrylate) graft copolymer having excellent impact absorption efficiency, the (meth)acrylate-based resin composition providing excellent transparency by exhibiting excellent impact resistance even using a small amount of impact modifier. The (meth)acrylate-based resin composition having excellent impact resistance and transparency comprises 1 to 29 wt % of the (conjugated diene-(meth)acrylate) graft copolymer and 71 to 99 wt % of the poly(alkyl(meth)acrylate-phenyl(meth)acrylate) copolymer. | 04-28-2016 |
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| 20130122685 | Method of Manufacturing a Semiconductor Device - A method of manufacturing a semiconductor device, the method including: forming a plurality of first trenches extending in one direction in at least a part of a substrate; forming a plurality of first filling layers for filling the plurality of first trenches and having protrusion portions extended from the substrate from the plurality of first trenches; forming spacers on side walls of the protrusion portions of the plurality of first filling layers so that a part of the substrate is exposed between the plurality of first filling layers; and forming a plurality of second trenches extending in parallel to the plurality of first trenches by etching the substrate exposed through the spacers. | 05-16-2013 |
| 20130234090 | SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME - A semiconductor device includes a first semiconductor layer extending in a first direction on a substrate, a plurality of second semiconductor layers spaced apart in the first direction on the first semiconductor layer, and an insulation layer structure surrounding side walls of the first semiconductor layer and the plurality of second semiconductor layers. The first semiconductor layer may have a first conductivity type, and the plurality of second semiconductor layers may have a second conductivity type. | 09-12-2013 |
| 20160020251 | MAGNETORESISTIVE RANDOM ACCESS MEMORY DEVICES AND METHODS OF MANUFACTURING THE SAME - An MRAM device may include semiconductor structures, a common source region, a drain region, a channel region, gate structures, word line structures, MTJ structures, and bit line structures arranged on a substrate. Each of the semiconductor structures may include a first semiconductor pattern having a substantially linear shape extending in a first direction that is substantially parallel to a top surface of the substrate, and a plurality of second patterns that each extend in a third direction substantially perpendicular to the top surface of the substrate. A common source region and drain region may be formed in each of the semiconductor structures to be spaced apart from each other in the third direction, and the channel region may be arranged between the common source region and the drain region. Gate structures may be formed between adjacent second semiconductor patterns in the second direction. Word line structures may electrically connect gate structures arranged in the first direction to each other. MTJ structures may be electrically connected to corresponding ones of the second semiconductor patterns. Each bit line structure may electrically connect two adjacent MTJ structures in the first direction to each other. | 01-21-2016 |
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| 20110096677 | APPARATUS AND METHOD FOR CONTROLLING UPLINK DEDICATED CHANNEL IN A MOBILE COMMUNICATION SYSTEM - A method for controlling an uplink dedicated channel by a Node B in a mobile communication system. The Node B generates configuration decision information including a UE Transmission Power Headroom (UPH) included in scheduling information received from a User Equipment (UE), and determines if there is a need for a change in the uplink dedicated channel configuration information based on the configuration decision information. When there is a need for a change in the uplink dedicated channel configuration information, the Node B sends to a Radio Network Controller (RNC) the configuration decision information and a message for requesting a change in the uplink dedicated channel configuration information. The Node B receives changed uplink dedicated channel configuration information that the RNC generated based on the configuration decision information. | 04-28-2011 |
| 20150026280 | APPARATUS AND METHOD FOR IMPROVED ELECTRONIC MAIL - An E-mail apparatus and method are provided. The e-mail apparatus includes a memory that stores display names and e-mail addresses corresponding to the display names, and a controller that extracts an e-mail address from a received e-mail message, retrieves from the memory a display name corresponding to the extracted e-mail address, modifies the display name of the received e-mail message to the retrieved display name, and outputs the modified display name. | 01-22-2015 |
| 20150189540 | QOS SWITCHING METHOD AND APPARATUS FOR QOS IN A WIRELESS COMMUNICATION SYSTEM - Quality of Service (QoS) switching method and apparatus in a mobile communication system are provided. The method includes determining, based on a total resource usage for providing a plurality of QoSs, the QoS switching relating to level adjustment of the plurality of QoSs corresponding to one of downgrade, upgrade, and grade maintenance, and adjusting levels of the plurality of QoSs according to the determined QoS switching. | 07-02-2015 |
| 20150323199 | BOILER SYSTEM USING FUEL CELL - Disclosed is a boiler system using a fuel cell including a boiler installed in a home, a building, or the like, a fuel cell for generating electricity and reaction heat by electrochemical reaction between a fuel and oxygen, a storage tank for recovering and storing the reaction heat generated by the fuel cell with a fluid, a room heating line buried beneath a room floor of the home, the building, or the like, a warm water line connected to supply warm water to a washroom or a kitchen of the home or the building through the boiler or the storage tank when water is supplied thereto from the outside, and a suction and exhaust integrated pipe having at least two of at least one first exhaust line, at least one first suction line of the boiler, at least one second exhaust line, and at least one second suction line of the fuel cell connected thereto to be used in common. | 11-12-2015 |
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| 20090093243 | RADIO LINK PARAMETER UPDATING METHOD IN MOBILE COMMUNICATION SYSTEM - A radio link (RL) parameter updating method of a high speed downlink packet access (HSDPA) system in a mobile communication system is disclosed. According to a radio channel situation of a terminal, an RL parameter applied to transmission and reception of control information between the terminal and a base station is dynamically controlled. For this purpose, the RL parameter updating method includes: a step in which the base station determines whether to update an HSDPA related parameter and transmits the parameter update information to the RNC to trigger updating of the RL parameter; and a step in which the RNC updates the HSDPA related parameter and transmits it to the terminal. The parameter update information is delivered through an RL parameter update response message, and the RNC is a serving RNC. | 04-09-2009 |
| 20100105727 | NOVEL BENZAMIDE DERIVATIVES AND PROCESS FOR THE PREPARTION THEREOF - The present invention provides a novel benzamide derivative represented by formula 1 and an isomer, a pharmaceutically acceptable salt or hydrate thereof, and a composition for activating a 5-HT4 receptor comprising the same, as an active ingredient. Benzamide derivatives of the present invention has superior affinity for 5-HT4 receptors, capability to reduce the gastric evacuation time, capability to alleviate ventricular tachycardia, ventricular fibrillation, torsades de pointes and QT prolongation, and low toxicity. Therefore, benzamide derivatives of the present invention are therapeutically effective for digestive system diseases. | 04-29-2010 |
| 20130124140 | Apparatus and Method for Driving Touch Sensor - Disclosed herein is an apparatus and method for driving a touch sensor, which is capable of improving touch sensitivity and accuracy. The touch sensor driving apparatus includes a touch sensor; a read-out circuit; and a signal processor configured to compare raw data from the read-out circuit with a predetermined primary reference value and secondary reference value so as to determine whether the touch node has been touched, wherein the signal processor collects the raw data of each touch node or each channel during a plurality of frames and resets and updates the secondary reference value of each touch node or each channel using the collected raw data. | 05-16-2013 |
| 20140042774 | FRONT SIDE MEMBER ASSEMBLY AND METHOD OF ASSEMBLING THE SAME - A front side member assembly includes a front side member body having at least one coupling hole at one surface thereof with a closed section shape, a bulkhead including a coupling portion and expansion foam that may be coupled to the coupling portion, wherein the bulkhead may be inserted into the front side member body in order to position the coupling portion at a position corresponding to the coupling hole, and the expansion foam may be hardened to reinforce rigidity of the front side member body. | 02-13-2014 |
| 20150370356 | TOUCH PANEL AND APPARATUS FOR DRIVING THEREOF - Embodiments relate to a touch panel and a method of operating the touch panel. The touch panel includes first electrodes and second electrodes separated from and intersecting the first electrodes. The first electrodes are applied with a touch driving pulse during a first sensing mode and a second sensing mode. The second electrodes sense a first touch sense signal responsive to the touch driving pulse in the first sensing mode. A subset of the second electrodes senses a second touch sense signal responsive to the touch driving pulse in the second sensing mode. | 12-24-2015 |
| 20160039804 | NOVEL OXAZOLIDINONE DERIVATIVE AS CETP INHIBITOR, ITS PREPARATION METHOD, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME - Disclosed are a novel oxazolidinone derivative exhibiting inhibitory activity against CETP, a preparation method thereof, and a pharmaceutical composition comprising the same. Exhibiting excellent inhibitory activity against CETP, the oxazolidinone derivative can be effectively applied to the prevention or treatment of various CETP enzyme activity- or HDL cholesterol level-related diseases such as dyslipidemia, atherosclerosis, and coronary heart disease. | 02-11-2016 |
| 20160051558 | PHARMACEUTICAL COMPOSITION FOR INHIBITING IMMUNE RESPONSE THROUGH INDUCING DIFFERENTIATION INTO REGULATOR T CELLS AND PROMOTING PROLIFERATION OF REGULATOR T CELLS - The present invention relates to new medical use of (tetrahydropyran-4-yl)-[2-phenyl-5-(1,1-dioxo-thiomorpholine-4-yl)methyl-1H-indol-7-yl]amine, and more particularly, to a pharmaceutical composition containing the compound as an active ingredient, which is used for inhibiting an immune response, and/or for inducing differentiation into regulator T cells from undifferentiated T cells and/or promoting proliferation of regulator T cells. | 02-25-2016 |
| 20160062504 | TOUCH PANEL AND APPARATUS FOR DRIVING THEREOF - Disclosed is a touch sensing display device capable of sensing both touch position and touch force, shortening a driving time for the touch sensing, and improving touch sensing efficiency, and an apparatus for driving thereof. The display device can include a color filter, a plurality of first touch electrodes for touch force sensing, and a plurality of second touch electrodes for touch position sensing and separated from the first touch electrodes by the color filter. The display can also include a force sensing touch driver for the first touch electrodes and a touch position touch driver for the second touch electrodes. | 03-03-2016 |
| 20160062505 | TOUCH PANEL HAVING A PLURALITY OF DUMMY SENSING ELECTRODES AND HAPTIC EFFECT - Embodiments relate to a touch panel with a haptic function and a method of operating the touch panel. The touch panel includes first electrodes and second electrodes intersecting the first electrodes. The touch panel further includes an elastic dielectric member disposed between the first electrodes and the second electrodes to separate the first electrodes and the second electrodes. The first electrodes are applied with a touch driving pulse during a sensing mode, and are applied with a voltage during a haptic mode. The second electrodes sense a touch sense signal responsive to the touch driving pulse in the sensing mode, and the second electrodes are applied with a reference voltage in the haptic mode. The elastic dielectric member vibrates in response to the voltage applied to the first electrodes in the haptic mode. | 03-03-2016 |
| 20160062537 | APPARATUS FOR DRIVING OF TOUCH PANEL - Embodiments relate to a touch panel operable in a first haptic mode and a second haptic mode. The touch panel includes first electrodes and second electrodes intersecting the first electrodes. The touch panel further includes an elastic dielectric member disposed between the first electrodes and the second electrodes to separate the first electrodes and the second electrodes. The first electrodes are applied with a first voltage during the first haptic mode. The second electrodes are applied with a reference voltage in the first haptic mode. A subset of the second electrodes is applied with a second voltage to generate electrostatic force between the subset of the second electrodes and a user's finger in the second haptic mode. The elastic dielectric member vibrates in response to the first voltage applied to the first electrodes in the first haptic mode. | 03-03-2016 |
| 20160062542 | MOBILE TERMINAL DEVICE AND DRIVING METHOD THEREOF - Disclosed is a mobile terminal device in which a locking mode is released based on a touch intensity in order to prevent an unlocking operation by an unintended touch, and a driving method thereof, wherein the driving method includes detecting a touch intensity for each touch when a plurality of touches occur in a locking mode, and releasing the locking mode on the basis of the plurality of touch intensities detected, or executing a function corresponding to the plurality of touch intensities detected. | 03-03-2016 |
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| 20140212715 | RECHARGEABLE BATTERY - A rechargeable battery includes an electrode assembly including a separator and electrode layers on opposite sides of the separator, the electrode assembly being wound such that curved surface portions are at opposing sides of the electrode assembly and a plane surface portion is between the curved surface portions, a pressing member that presses at least one part of the curved surface portions and the plane surface portion, a case containing the pressing member and the electrode assembly, and a cap plate electrically connected to the electrode assembly and coupled to the case. | 07-31-2014 |
| 20140288860 | DEVICE FOR MEASURING LENGTH OF ELECTRODE PLATE - A system for measuring a length of an electrode plate includes a body on which an electrode plate roll formed by spirally winding the electrode plate is provided; a control device to which the body is combined; and a measuring device including a thickness measurement unit combined with the body and electrically connected to the control device to measure a spirally wound thickness of the electrode plate that is spirally wound on the electrode plate roll, and a diameter measurement unit to measure a diameter of a hollow portion of the electrode plate roll, wherein the control device receives a moving distance of the thickness measurement unit and a moving distance of the diameter measurement unit and calculates the length of the electrode plate of the electrode plate roll. | 09-25-2014 |
| 20140295232 | RECHARGEABLE BATTERY AND METHOD OF MANUFACTURING THE SAME - A rechargeable battery including; an electrode assembly including a separator; a first electrode on a first surface of the separator; a second electrode on a second surface of the separator; and an electrolyte solution at a first interface of the first electrode and the separator and a second interface of the second electrode and the separator, the electrode assembly being spiral-wound and being impregnated with an electrolyte solution; an insulation tape wrapping the electrode assembly; a case housing the electrode assembly that is coated with the insulation tape; and a cap plate coupled to the case and electrically connected to the electrode assembly. | 10-02-2014 |
| 20160043403 | POSITIVE ELECTRODE COMPOSITION FOR RECHARGEABLE LITHIUM BATTERY, AND POSITIVE ELECTRODE FOR RECHARGEABLE LITHIUM BATTERY AND RECHARGEABLE LITHIUM BATTERY INCLUDING THE SAME - A positive electrode composition for a rechargeable lithium battery includes a positive active material, a spherically shaped conductive material, and a sheet-shaped conductive material. The spherically shaped conductive material is included in an amount of about 1.1 to about 10 parts by weight based on 1 part by weight of the sheet-shaped conductive material. A positive electrode includes the positive electrode composition and a rechargeable lithium battery includes the positive electrode. | 02-11-2016 |
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| 20090175248 | APPARATUS AND METHOD FOR TRANSMITTING AND RECEIVING ENHANCED RACH IN A MOBILE COMMUNICATION SYSTEM - A method for transmitting an enhanced Random Access CHannel (RACH) in a User Equipment (UE) in a mobile communication system is provided, in which the UE transmits an uplink preamble to a Node B and upon receipt of an ACKnowledgment (ACK) for the uplink preamble, transmits an Enhanced Uplink Dedicated CHannel (E-DCH) and a Dedicated Physical Control CHannel (DPCCH) to the Node B. The transmission of the DPCCH starts before the transmission of the E-DCH. | 07-09-2009 |
| 20100227562 | METHOD AND APPARATUS FOR ELIMINATING MULTI-USER INTERFERENCE IN MULTI-ANTENNA SYSTEM - A method and an apparatus are provided for eliminating multi-user interference in a multi-antenna system. In a BS, precoding vector information of at least one interfering user terminal interfering with a user terminal and information about a ratio of the transmission (TX) power of the user terminal to the total TX power of the BS are detected. A control signal including the detected information is transmitted to the user terminal. | 09-09-2010 |
| 20110243014 | METHOD AND APPARATUS FOR UPLINK SCHEDULING IN A COMMUNICATION SYSTEM - A method and apparatus for uplink scheduling in a communication system are provided. The method includes determining whether a User Equipment (UE) is included in an uplink scheduling list, a buffer length of the UE is estimated, if the UE is included in the uplink scheduling list, it is determined whether a Buffer State Report (BSR) indicating the buffer length of the UE has been received from the UE, if the estimated buffer length is 0, and the UE is transitioned to a non-zero BSR reception state and maintained in the uplink scheduling list, if the BSR has not been received from the UE. The non-zero BSR reception state is a state in which a zero BSR indicating the buffer length of the UE is 0 has not been received. | 10-06-2011 |
| 20120036528 | METHOD AND APPARATUS FOR SENDING NOTIFICATION ABOUT BROADCAST SERVICE IN A MOBILE BROADCAST SYSTEM - A method and apparatus for transmitting a notification about broadcasting services in a broadcasting system are provided. The method includes detecting a notification event related to a broadcasting service; generating a notification message about the notification event; determining which channel is used for a transmission of the notification message; and transmitting the notification message to a terminal or a group of terminals over the determined channel. | 02-09-2012 |
| 20140016059 | POLARIZER, DISPLAY PANEL HAVING THE SAME AND METHOD OF MANUFACTURING THE SAME - A polarizer includes a substrate, and a first metal layer and a second metal layer disposed on the substrate. The first metal layer includes a plurality of protrusions of a wire grid pattern. Each protrusion has a first width and adjacent protrusions are spaced apart by a second width. The second metal layer is disposed on each of the protrusions of the first metal layer, and includes molybdenum (Mo) and/or titanium (Ti). | 01-16-2014 |
| 20140169307 | METHOD AND APPARATUS FOR UPLINK SCHEDULING IN A COMMUNICATION SYSTEM - A method and apparatus for uplink scheduling in a communication system are provided. The method includes determining whether a User Equipment (UE) is included in an uplink scheduling list, a buffer length of the UE is estimated, if the UE is included in the uplink scheduling list, it is determined whether a Buffer State Report (BSR) indicating the buffer length of the UE has been received from the UE, if the estimated buffer length is 0, and the UE is transitioned to a non-zero BSR reception state and maintained in the uplink scheduling list, if the BSR has not been received from the UE. The non-zero BSR reception state is a state in which a zero BSR indicating the buffer length of the UE is 0 has not been received. | 06-19-2014 |
| 20150092140 | WIRE GRID POLARIZER, DISPLAY DEVICE INCLUDING THE SAME, AND METHOD OF FABRICATING THE WIRE GRID POLARIZER - A wire grid polarizer including a substrate, parallel conductive wire patterns which protrude from a top surface of the substrate, non-conductive wire patterns which are formed on the conductive wire patterns, respectively, and a protective layer which is formed on the conductive wire patterns and the non-conductive wire patterns. The protective layer includes first transparent particles having a diameter greater than a period of the conductive wire patterns, and spaces between the conductive wire patterns are filled with air or are evacuated to form a vacuum. | 04-02-2015 |
| 20160026034 | POLARIZER AND DISPLAY PANEL HAVING THE SAME - A polarizer includes a base substrate, a polarizing layer disposed on the base substrate and including a plurality of first linear extensions spaced apart from each other, and an ultraviolet (UV)-blocking layer including a plurality of second linear extensions spaced apart from each other and crossing the first linear extensions. The polarizer may block an external UV light. | 01-28-2016 |
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| 20110178091 | ARYLPIPERAZINE-CONTAINING PYRROLE 3-CARBOXAMIDE DERIVATIVES FOR TREATING DEPRESSIVE DISORDERS - The present invention relates to novel arylpiperazine-containing pyrrole 3-carboxamide derivatives of formula (I) or a pharmaceutically acceptable salt thereof which is useful for preventing or treating depressive disorders. The present invention also provides a method for preparing the arylpiperazine-containing pyrrole 3-carboxamide derivatives or the pharmaceutically acceptable salt thereof, a pharmaceutical composition containing same, and a method for preventing or treating depressive disorders. | 07-21-2011 |
| 20120115881 | NOVEL ARYLPIPERAZINE-CONTAINING IMIDAZOLE 4-CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME - A novel arylpiperazine-containing imidazole 4-carboxamide derivative or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same as an active ingredient for preventing or treating a depressive disorder are provided. | 05-10-2012 |
| 20120232090 | ARYLPIPERAZINE-CONTAINING PURINE DERIVATIVES AND USES THEREOF - A novel arylpiperazine-containing purine derivatives and a pharmaceutical composition comprising the same as an active ingredient, which are useful for preventing or treating depressive disorders, are provided. | 09-13-2012 |
| 20130090298 | Thiazole Derivatives as SGLT2 Inhibitors and Pharmaceutical Composition Comprising Same - The present invention relates to a novel compound with thiazole ring having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney, and a pharmaceutical composition comprising the same as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly diabetes. | 04-11-2013 |
| 20140088079 | NOVEL DIPHENYLMETHANE DERIVATIVES AS SGLT2 INHIBITORS - The present invention relates to a compound with a diphenylmethane moiety having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney, and a pharmaceutical composition comprising the same as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly diabetes. The present invention also provides a method for preparing the compound, and a method for preventing or treating metabolic disorders, particularly diabetes, by using the compound. | 03-27-2014 |
| 20140274918 | METHOD FOR DUAL INHIBITION OF SGLT1 AND SGLT2 USING DIPHENYLMETHANE DERIVATIVES - The present invention relates to a method for dual inhibition of sodium-dependent glucose cotransporter 1 (SGLT1) and sodium-dependent glucose cotransporter 2 (SGLT2) present in the intestine and kidney by using the compound of formula I or a pharmaceutically acceptable salt or a prodrug thereof: | 09-18-2014 |
| 20150152075 | NOVEL DIPHENYLMETHANE DERIVATIVES AS SGLT2 INHIBITORS - A compound with a diphenylmethane moiety having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney is disclosed. A pharmaceutical composition including the compound as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly diabetes is disclosed. A method for preparing the compound, and a method for preventing or treating metabolic disorders, particularly diabetes, by using the compound is provided. | 06-04-2015 |
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| 20120248418 | ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE - An organic electroluminescent display device includes a first substrate including a display region including a plurality of pixel regions; a first electrode in each pixel region; an organic light emitting layer on the first electrode; a second electrode on the organic light emitting layer and in the display region, wherein the second electrode includes a first metal material having a first wt %, a first work function, and a first sheet resistance, and a second metal material having a second wt % less than the first wt %, a second work function less than the first work function, and a second sheet resistance greater than the first sheet resistance. | 10-04-2012 |
| 20140061599 | Organic Light Emitting Display Device - An organic light emitting display device with improved thermal reliability is disclosed. The organic light emitting display device includes a substrate, and an organic light emitting device that includes a first electrode, an organic light emitting layer including a first host, a second host, and a dopant, and a second electrode sequentially stacked on the substrate. The first host and the second host have different glass transition temperatures. | 03-06-2014 |
| 20140183492 | ORGANIC LIGHT EMITTING DISPLAY DEVICE AND METHOD OF MANUFACTURING THE SAME - An organic light emitting display device includes a first electrode formed on a substrate, a second electrode facing the first electrode, a blue emission layer formed between the first and second electrodes, a capping layer formed on the second electrode, and a front sealing layer formed on the capping layer and comprising an inorganic barrier layer and an organic barrier layer alternately formed at least once, wherein a luminescent dopant included in the blue emission layer has a maximum photoluminescence wavelength of 465 nm or less, and blue light generated from the blue emission layer and emitted via the front sealing layer or the substrate has a Y color coordinate (CIEy) of 0.055 or less. | 07-03-2014 |
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| 20100129373 | VEGF-SPECIFIC HUMAN ANTIBODY - The present invention relates to a vascular endothelial growth factor (VEGF)-specific human antibody, and more particularly to a human antibody including a complementarity determining region (CDR) and a framework region (FR) derived from a human antibody specifically bound to VEGF. The VEGF-specific human antibody of the present invention may be used in diagnosis of diseases caused by the VEGF-overexpression, classification of the diseases, visualization, treatment, and prognostic evaluation. | 05-27-2010 |
| 20110189087 | TMPRSS4-Specific Human Antibody - The present invention relates to a transmembrane protease, serine (TMPRSS4)-specific human antibody, and more particularly to a human antibody including a complementarity determining region (CDR) and a framework region (FR) derived from a human antibody specifically bound to TMPRSS4. The TMPRSS4-specific human antibody expressed in the various kinds of cancer cells of the present invention may be used in diagnosis of the cancer, classification of the disease, visualization, treatment, and prognostic evaluation. | 08-04-2011 |
| 20110195027 | CD9-SPECIFIC HUMAN ANTIBODIES - The present invention relates to a CD9-specific human antibody, more precisely a CD9-specific human antibody composed of human derived CD9-specific complementarity determining region (CDR) and framework region (FR). The human antibody of the present invention recognizes CD9 extracellular loop 2 domain (CD9-ECL2) as an epitope and thereby strongly binding thereto. The human antibody of the present invention also has CD9 antigen neutralizing effect and at the same time inhibiting effect on tumor cell lines. Therefore, it can be effectively used for the prevention and treatment of cancer overexpressing CD9. | 08-11-2011 |
| 20130017226 | TNF-A and TWEAK Dual Antagonist for the Prophylaxis and Treatment of Autoimmune DiseasesAANM Park; Young WooAACI DaejeonAACO KRAAGP Park; Young Woo Daejeon KRAANM Jo; Ki WonAACI Gyeonggi-doAACO KRAAGP Jo; Ki Won Gyeonggi-do KRAANM Yoo; Srok HoAACI DaejeonAACO KRAAGP Yoo; Srok Ho Daejeon KRAANM Yu; JungAACI DaejeonAACO KRAAGP Yu; Jung Daejeon KRAANM Kim; Dong JiAACI DaejeonAACO KRAAGP Kim; Dong Ji Daejeon KRAANM Yoon; Sun-HaAACI DaejeonAACO KRAAGP Yoon; Sun-Ha Daejeon KRAANM Song; Eun JungAACI DaejeonAACO KRAAGP Song; Eun Jung Daejeon KRAANM Lee; Eun KyungAACI Gyeonggi-doAACO KRAAGP Lee; Eun Kyung Gyeonggi-do KRAANM Oh; Jin MiAACI Gyeonggi-doAACO KRAAGP Oh; Jin Mi Gyeonggi-do KRAANM Cho; Kyu WonAACI SeoulAACO KRAAGP Cho; Kyu Won Seoul KRAANM Cho; Mi LaAACI SeoulAACO KRAAGP Cho; Mi La Seoul KRAANM Kim; Ho YounAACI SeoulAACO KRAAGP Kim; Ho Youn Seoul KRAANM Park; Mi KyungAACI Gyeonggi-doAACO KRAAGP Park; Mi Kyung Gyeonggi-do KRAANM Oh; Hye JwaAACI SeoulAACO KRAAGP Oh; Hye Jwa Seoul KRAANM Park; Jin SilAACI SeoulAACO KRAAGP Park; Jin Sil Seoul KRAANM Woo; Yun JuAACI SeoulAACO KRAAGP Woo; Yun Ju Seoul KRAANM Byun; Jae KyeongAACI Chungcheongbuk-doAACO KRAAGP Byun; Jae Kyeong Chungcheongbuk-do KRAANM Ryu; Jun GeolAACI Gangwon-doAACO KRAAGP Ryu; Jun Geol Gangwon-do KR - The present invention relates to TNFR2-TWEAKR fusion protein, more precisely to TNFR2-TWEAKR fusion protein acting as a double-antagonist to TNF-α and TWEAK, known as major causes of autoimmune arthritis which is one of autoimmune diseases. When the composition comprising TNFR2-TWEAKR fusion protein was treated to Th17 cells, the secretion of the inflammatory cytokine IL-17 was reduced but the secretion of the anti-inflammatory cytokine IL-10 generated in Treg cells was increased. Such effect of TNFR2-TWEAKR fusion protein was far greater than that of a single protein such as TNFR2-Fc or TWEAK-Fc. The TNFR2-TWEAKR fusion protein of the present invention has not only excellent treatment effect on arthritis in CIA mouse model not also excellent treatment effect on autoimmune rheumatoid arthritis by increasing the expression of Treg, the immune suppressive cells. Therefore, the TNFR2-TWEAKR fusion protein of the present invention can be effectively used as an active ingredient for the composition for the prevention and treatment of autoimmune disease. | 01-17-2013 |
| 20130022642 | Dual Antagonist for TNF-A and IL-21 for Preventing and Treating Autoimmune Diseases - The present invention relates to TNFR2-IL21R fusion protein acting as a double-antagonist to TNF-alpha (α) and IL-21. The composition containing the double antagonist to TNF-α and Il-21 (TNFR2-IL21R fusion protein), known as major causes of autoimmune rheumatoid arthritis, one of autoimmune diseases, can reduce the secretion of inflammatory cytokine, increase the secretion of anti-inflammatory cytokine, and suppress the differentiation of osteoclasts better than single proteins such as TNFR2-Fc and IL21R-Fc. The TNFR2-IL21R fusion protein of the present invention has not only excellent treatment effect on arthritis in CIA mouse model not also excellent treatment effect on autoimmune rheumatoid arthritis by increasing the expression of Treg, the immune suppressive cells. Therefore, the TNFR2-IL21R fusion protein of the present invention can be effectively used as an active ingredient for the composition for the prevention and treatment of autoimmune disease. | 01-24-2013 |
