Egbertson
Erik Egbertson, Medford, MA US
Patent application number | Description | Published |
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20080249749 | INTERACTIVE TRUSS OBJECTS IN COMPUTER-AIDED DESIGN MODELS - Embodiments of the invention provide a computer-aided design (CAD) application configured for generating interactive truss objects in a CAD model. In one embodiment, a truss creation tool allows the user to select a truss family and the endpoints of the truss. Based on these selections, the truss creation tool generates a layout and structural members of a truss. The truss may be maintained as an interactive object within the CAD model. Thus, a user may edit the truss object, resulting in the regeneration of the truss layout and the regeneration of the structural elements of the truss. | 10-09-2008 |
Melissa Egbertson, Ambler, PA US
Patent application number | Description | Published |
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20090054399 | HIV INTEGRASE INHIBITORS - Tricyclic compounds of Formula (I) are inhibitors of HIV integrase and inhibitors of HIV replication: wherein bond a, ring A, R | 02-26-2009 |
20120115885 | Quinolinone PDE2 Inhibitors - The present invention is directed to quinolinone compounds which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 2 (PDE2). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction. | 05-10-2012 |
20120196894 | NOVEL TRPA1 ANTAGONISTS - The present invention relates to compositions and methods that modulate at least one TRP family member. Specifically, the present invention relates to novel TRPA1 antagonists and their use in the treatment of pain such as chronic inflammatory and neuropathic pain. Compounds that can modulate one or more TRPA1 functions are useful in many aspects including, but not limited to, maintaining calcium homeostasis; maintaining sodium homeostasis; modulating intracellular calcium levels; modulating membrane polarization (membrane potential); modulating cation levels; and/or treating or preventing diseases, disorders, or conditions associated with calcium homeostasis, sodium homeostasis, calcium or sodium dyshomeostasis, or membrane polarization/hyperpolarization (including hypo and hyperexcitability), and/or treating or preventing diseases, disorders, or conditions associated with regulation or misregulation of TRPA1 expression or function. The present invention further relates to methods and compositions that antagonize both a function of TRPA1 and a function of one or more additional TRP channels. | 08-02-2012 |
20130178468 | HIV INTEGRASE INHIBITORS - Tricyclic compounds of Formula I are inhibitors of HIV integrase and inhibitors of HIV replication: | 07-11-2013 |
Melissa S. Egbertson, Ambler, PA US
Patent application number | Description | Published |
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20080287394 | Hiv Integrase Inhibitors - Hydroxy-substituted pyrazinopyrrolopyridazine dione compounds are inhibitors of HIV integrase and inhibitors of HIV replication. In one embodiment, the dione compounds are of Formula (I) wherein R | 11-20-2008 |
20100298342 | Spiropiperidine beta-secretase inhibitors for the treatment of Alzheimer's Disease - The present invention is directed to spiropiperidine compounds of formula (I) and tautomers thereof, which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved. | 11-25-2010 |