Patent application number | Description | Published |
20110262925 | METHODS FOR ISOLATING A TARGET ANALYTE FROM A HETEROGENEOUS SAMPLE - The invention generally relates to methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample. | 10-27-2011 |
20110262927 | ANALYZING BACTERIA WITHOUT CULTURING - The invention generally relates to conducting an assay on a sample that isolates a pathogen from the sample and allows for analysis of the pathogen with minimal (i.e., at most | 10-27-2011 |
20110262932 | COMPOSITIONS - The invention generally relates to compositions that include magnetic particles bound to pathogens in a body fluid. | 10-27-2011 |
20110262989 | ISOLATING A TARGET ANALYTE FROM A BODY FLUID - The invention generally relates to using magnetic particles and magnets to isolate a target analyte from a body fluid sample. In certain embodiments, methods of the invention involve introducing magnetic particles including a target-specific binding moiety to a body fluid sample in order to create a mixture, incubating the mixture to allow the particles to bind to a target, applying a magnetic field to capture target/magnetic particle complexes on a surface, and washing with a wash solution that reduces particle aggregation, thereby isolating target/magnetic particle complexes. | 10-27-2011 |
20110263833 | COMPOSITIONS FOR ISOLATING A TARGET ANALYTE FROM A HETEROGENEOUS SAMPLE - The invention generally relates to compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen. | 10-27-2011 |
20130109590 | ISOLATING A TARGET ANALYTE FROM A BODY FLUID | 05-02-2013 |
20130316355 | METHODS FOR ISOLATING A TARGET ANALYTE FROM A HETEROGENEOUS SAMPLE - The invention generally relates to methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample. | 11-28-2013 |
20140100136 | ISOLATION AND CHARACTERIZATION OF PATHOGENS - Methods of the invention generally involve using magnetic particles to isolate low levels of pathogens from a samples and identifying genes expressed by those pathogen. In one aspect, the method includes obtaining a sample comprising a pathogen, forming magnetic particle/target complexes, separating the magnetic particle/target complexes using magnetic fields, and determining an expression profile of a nucleic acid derived from the target. | 04-10-2014 |
20140170652 | TARGET CAPTURE SYSTEM - The invention generally relates to a system for isolating or separating a target from a sample. In certain aspects, processes performed by the target capture system include introducing a plurality of magnetic particles, in which a plurality of the particles include at least one binding moiety specific to a target, into a sample to form at least one target/particle complex and applying a magnetic field to isolate the magnetic particle/target complexes from the sample. The process starts at inputting a sample into the system and ends at delivering a capture target or nucleic acids of the target into a container for further analysis. | 06-19-2014 |
20140170667 | METHODS FOR AMPLIFYING NUCLEIC ACID FROM A TARGET - The invention generally relates to methods for amplifying nucleic acid from a target. In certain aspects, methods of the invention involve obtaining a sample including a target, conducting an assay that isolates the target from the sample, lysing the target to release the nucleic acid, and amplifying the released nucleic acid such that the amplifying occurs in the presence of debris from the lysing step. | 06-19-2014 |
20140171340 | METHODS FOR RAISING ANTIBODIES - The present invention generally relates to methods of generating antibodies against a species of pathogen that involve identifying the pathogen that is most genetically representative of member of pathogen species and using the identified pathogen to generate an antibody. | 06-19-2014 |