Didonato
Blaise Didonato, Keego Harbor, MI US
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20140252724 | SELF-RETAINING GASKET - A self-retaining gasket including a main body, a first retention tab, and a second retention tab. The main body includes a first surface and a second surface opposite to the first surface. The main body defines a first aperture extending between the first surface and the second surface. The first retention tab and the second retention tab extend from the main body at the first aperture. | 09-11-2014 |
Christine Mary Didonato, San Diego, CA US
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20130219434 | 3D BODY SCAN INPUT TO TV FOR VIRTUAL FITTING OF APPAREL PRESENTED ON RETAIL STORE TV CHANNEL - A retail store TV shopping channel may be an IPTV channel dedicated to a single retail store. 3D images of apparel items selected by a viewer of the retail store TV shopping channel are presented on the TV, overlaid on a 3D image of the viewer. Revenue is shared between the TV manufacturer and retail store. | 08-22-2013 |
David Didonato, Geneva, IL US
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20130229067 | CONNECTOR HAVING WIRELESS CONTROL CAPABILITIES - A connector for connecting a source of low-voltage DC power to a low-voltage DC powered device includes a line-side interface arranged for releasably and electrically coupling the connector to the source of low-voltage DC power, a line-side interface arranged for electrically coupling the connector to the low-voltage DC powered device, a power controller electrically coupled to the line-side interface and the load-side interface and operarable to control a bringing of power to the load-side interface from the line-side interface, and an RF receiver electrically coupled to the power controller for receiving a first signal from a device external to the connector and for generating, in response thereto, a second signal for controlling operations of the power controller. | 09-05-2013 |
Joe Didonato, Lorain, OH US
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20110104818 | CARBAMYLATED PROTEINS AND RISK OF CARDIOVASCULAR DISEASE - Methods for characterizing a test subject's, particularly a human test subject's, risk of having cardiovascular disease or developing cardiovascular disease are provided. Also provided are methods for characterizing a test subject's risk of experiencing a complication of cardiovascular disease near term. The methods comprise determining levels of one or more carbamylated biomarkers in a bodily fluid of the test subject and/or comparing these levels with a reference value. In certain embodiments, the carbamylated biomarkers are carbamylated albumin, carbamylated fibrinogen, carbamylated immunoglobulin and carbamylated apolipoprotein A. In other embodiments, particularly where the test subject does not have clinical evidence of renal disease, the carbamylated biomarker is free and/or total peptide-bound homocitrulline. | 05-05-2011 |
Joseph Didonato, Westlake, OH US
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20110305707 | COMPOSITIONS AND METHODS FOR TREATING CANCER - The present invention provides methods for treating cancer in a subject, as well as related compositions and kits that employ a therapeutic agent, or a nucleic acid sequence encoding a therapeutic agent, selected from apolipoprotein A-1 (ApoA1) or biologically active fragment, an ApoA1 mimetic, an agent that increases expression of ApoA1, or a binding agent specific for oxidized ApoA1. In certain embodiments, the ApoA1 or ApoA1 mimetic is at least partially oxidation resistant. | 12-15-2011 |
Joseph A. Didonato, Westlake, OH US
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20090011982 | Flagellin Related Polypeptides and Uses Thereof - The use of flagellin and flagellin related polypeptides for the protection of mammals from the effects of apoptosis is described. | 01-08-2009 |
20100055714 | IKB kinase, subunits thereof, and methods of using same - The present invention provides an isolated nucleic acid molecules encoding IκB kinase (IKK) catalytic subunit polypeptides, which are associated with an IKK serine protein kinase that phosphorylates a protein (IκB) that inhibits the activity of the NF-κB transcription factor, vectors comprising such nucleic acid molecules and host cells containing such vectors. In addition, the invention provides nucleotide sequences that can bind to a nucleic acid molecule of the invention, such nucleotide sequences being useful as probes or as antisense molecules. The invention also provides isolated IKK catalytic subunits, which can phosphorylate an IκB protein, and peptide portions of such IKK subunit. In addition, the invention provides anti-IKK antibodies, which specifically bind to an IKK complex or an IKK catalytic subunit, and IKK-binding fragments of such antibodies. The invention further provides methods of substantially purifying an IKK complex, methods of identifying an agent that can alter the association of an IKK complex or an IKK catalytic subunit with a second protein, and methods of identifying proteins that can interact with an IKK complex or an IKK catalytic subunit. | 03-04-2010 |
20110319344 | FLAGELLIN RELATED POLYPEPTIDES AND USES THEREOF - The use of flagellin and flagellin related polypectides for the protection of mammals from the effects of apoptsis is described. | 12-29-2011 |
20110319595 | FLAGELLIN RELATED POLYPEPTIDES AND USES THEREOF - The use of flagellin and flagellin related polypectides for the protection of mammals from the effects of apoptsis is described. | 12-29-2011 |
20140294900 | FLAGELLIN RELATED POLYPEPTIDES AND USES THEREOF - The use of flagellin and flagellin related polypeptides for the protection of mammals from the effects of apoptsis is described. | 10-02-2014 |
Steven Didonato, Harleysville, PA US
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20080277422 | Wine preservation and dispensing apparatus - A preservation and dispensing apparatus includes a pressurized gas supply assembly for pressurizing and dispensing fluid from a bottle in a manner that effectively creates a barrier protecting the fluid from harmful effects of oxygen. The pressurized gas supply assembly includes an inert gas output linked to the bottle via a dispensing nozzle secured within an opening of the bottle. The dispensing nozzle includes a connecting seal having a series of outwardly directed, flexible fins composed of a first material and an outwardly tapered seal member composed of a second material. The inert gas output includes a regulator assembly having a piercing pin that passes through an end cap of a gas capsule allowing gas from the gas capsule to pass through the regulator assembly. The regulator assembly reduces the gas pressure from approximately 2700 psi to approximately 5 psi in a single step. | 11-13-2008 |
20110000250 | BEVERAGE PRESERVATION AND DISPENSING APPARATUS INCORPORATED WITHIN A REFRIGERATOR DOOR - A preservation and dispensing apparatus integrated within a refrigerator door includes a wine preservation and dispensing apparatus and a door of a refrigerator within which the wine preservation and dispensing apparatus is integrated. The wine preservation and dispensing apparatus includes a housing framework composed of a rigid frame secured to the refrigerator door along an opening cut into the door. | 01-06-2011 |
20110139828 | WINE PRESERVATION AND DISPENSING APPARATUS - A dispensing apparatus includes a housing having a support platform upon which at least one bottle may be supported and a pressurized gas supply assembly for forcing a fluid from the at least one bottle. The pressurized gas supply assembly includes an inert gas output which is linked to the at least one bottle via a conduit arrangement and a dispensing nozzle selectively secured within an opening of the at least one bottle. The dispensing nozzle includes a connecting seal assembly for attaching the dispensing nozzle within the opening of the at least one bottle, the connecting seal assembly extends downwardly and substantially covers a downwardly extending substrate of the dispensing nozzle, and the connecting seal assembly includes a self-energizing seal. | 06-16-2011 |
20120012616 | WINE PRESERVATION AND DISPENSING APPARATUS - A preservation and dispensing apparatus includes a pressurized gas supply assembly for pressurizing and dispensing fluid from a bottle in a manner that effectively creates a barrier protecting the fluid from harmful effects of oxygen. The pressurized gas supply assembly includes an inert gas output linked to the bottle via a dispensing nozzle secured within an opening of the bottle. The dispensing nozzle includes a connecting seal having a series of outwardly directed, flexible fins composed of a first material and an outwardly tapered seal member composed of a second material. The inert gas output includes a regulator assembly having a piercing pin that passes through an end cap of a gas capsule allowing gas from the gas capsule to pass through the regulator assembly. The regulator assembly reduces the gas pressure from approximately 2700 psi to approximately 5 psi in a single step. | 01-19-2012 |