Patent application number | Description | Published |
20080275092 | ARYL-SUBSTITUTED PYRAZOLE-AMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS - The present invention relates to compounds having the formula, | 11-06-2008 |
20100016320 | ARYL-SUBSTITUTED PYRAZOLE-AMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS - The present invention relates to compounds having the formula, | 01-21-2010 |
20100210629 | 1,6-DIHYDRO-1,3,5,6-TETRAAZA-AS-INDACENE BASED TRICYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME - The present invention provides for tricyclic compounds having the formula (I), | 08-19-2010 |
20110160207 | HETEROCYCLIC AMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS - A compound of Formula I | 06-30-2011 |
20120214767 | TRICYCLIC HETEROCYCLIC COMPOUNDS - Disclosed are compounds of Formula (I) | 08-23-2012 |
20130158001 | SUBSTITUTED 3-PHENYL-1,2,4-OXADIAZOLE COMPOUNDS - Disclosed are compounds of Formula (I): (I) or stereoisomers, salts, or prodrugs thereof, wherein: (i) R1 and R2 are independently C | 06-20-2013 |
20130190361 | SUBSTITUTED OXADIAZOLE COMPOUNDS - Disclosed are compounds of Formula (I): | 07-25-2013 |
20140005146 | PYRROLOPYRIDAZINE JAK3 INHIBITORS AND THEIR USE FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES | 01-02-2014 |
20140011800 | PYRROLOPYRIDAZINE JAK3 INHIBITORS AND THEIR USE FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES - The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of JAK3, thereby making them useful for the treatment of inflammatory and autoimmune diseases. | 01-09-2014 |
20140206691 | CYCLIC PROTEIN TYROSINE KINASE INHIBITORS - Novel cyclic compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of protein tyrosine kinase-associated disorders such as immunologic and oncologic disorders. | 07-24-2014 |
Patent application number | Description | Published |
20100247569 | Influenza A Virus Vaccines and Inhibitors - The present invention includes compositions and methods related to the structure and function of the cellular polyadenylation and specificity factor 30 (CPSF30) binding site on the surface of the influenza A non-structural protein 1 (NS1). Specifically, critical biochemical reagents, conditions for crystallization and NMR analysis, assays, and general processes are described for (i) discovering, designing, and optimizing small molecule inhibitors of influenza A (avian flu) viruses and (ii) creating attenuated influenza virus strains suitable for avian and human flu vaccine development. | 09-30-2010 |
20110244496 | HIV REVERSE TRANSCRIPTASE COMPOSITIONS AND METHODS - The present invention provides engineered novel variants of human immunodeficiency virus reverse transcriptase (HIV-RT) capable of being expressed in large quantity and that with polymerase and RNase H activity in a form that facilitates crystallization and high resolution structure resolution following X-ray diffraction. The present invention facilitates high resolution determination of RT in complexes with RT drugs and RT inhibitors, and provides methods for systematic generation of variants and for structure based identification and design of novel RT inhibitors. | 10-06-2011 |
20140044745 | Influenza A Virus Vaccines and Inhibitors - The present invention includes compositions and methods related to the structure and function of the cellular polyadenylation and specificity factor 30 (CPSF30) binding site on the surface of the influenza A non-structural protein 1 (NS1). Specifically, critical biochemical reagents, conditions for crystallization and NMR analysis, assays, and general processes are described for (i) discovering, designing, and optimizing small molecule inhibitors of influenza A (avian flu) viruses and (ii) creating attenuated influenza virus strains suitable for avian and human flu vaccine development. | 02-13-2014 |
Patent application number | Description | Published |
20080253390 | METHOD AND APPARATUS FOR PRIORITY SERVICES MANAGEMENT - Apparatus and method for adapting a control plane of a communications network normally using a call session control function (CSCF) in communication with a resource access control function (RACF) by providing a priority service functional element (PS-FE) to handle call admission and priority services. | 10-16-2008 |
20100034195 | Incremental addition and scale-back of resources adapting to network resource availability - An exemplary method includes receiving at a first network a notice of an intended communication to a called party network, wherein the intended communication requires a resource for supporting a streaming data protocol in each network between a calling party network and the called party network; forwarding the notice of an intended communication to a second network and toward the called party network; in parallel with said forwarding, initiating for the intended communication a determination of resource availability for the first network; performing for the intended communication the determination of resource availability for the first network, wherein the determination is for a first resource for the first network; and verifying resource sufficiency for the intended communication. Verification of resource sufficiency is based on resource, (e.g., bandwidth) availability being greater than a threshold for plural network segment of the calling party to calling network required for the intended call. | 02-11-2010 |
20100034196 | RPH mapping and defaulting behavior - An exemplary management method includes receiving at a first network a notice of an intended communication to a called party network, the notice including a first priority indicator, the intended communication requiring a resource for supporting a streaming data protocol in each network between a calling party network and the called party network; forwarding the notice to a second network and toward the called party network, the notice including the first priority indicator; in parallel with said forwarding, mapping the first priority indicator to a second priority indicator and initiating for the intended communication a determination of resource availability for the first network based on the second priority indicator; determining the determination of resource availability for the first network based on the second priority indicator, wherein the determination is for a first resource for the first network; and verifying resource availability for the intended communication. | 02-11-2010 |
20100034197 | End-to-end capacity and priority management through multiple packet network segments - Apparatus and method for management of a communications network are provided. An exemplary method includes receiving at a first network a notice of an intended communication to a called party network, wherein the intended communication requires at least one resource for supporting a streaming data protocol between a calling party network and the called party network; verifying resource availability of at least one resource in the first network; and in parallel with said verifying, forwarding the notice of an intended communication to a second network and toward the called party network prior to receiving an indication of resource availability of the at least one resource in the first network required for the intended communication. | 02-11-2010 |
20100034367 | Network call back to add conference participants and/or media capabilities - An exemplary method includes receiving at a calling party network a notice of an intended communication between a calling endpoint and a plurality of called endpoints located in a plurality of called party networks, wherein the intended communication requires a resource in each of the calling party network and the called party networks for supporting a streaming data protocol. The notice is forwarded toward the plurality of called party networks and in parallel with said forwarding, a determination of resource availability for the calling party network is initiated for the intended communication. The method further includes determining for the intended communication the determination of resource availability for the calling party network, wherein the determination is for a first resource for the first network; and verifying resource availability for the intended communication based on the determination for the calling party network and a resource availability indicator for each called party network. | 02-11-2010 |
Patent application number | Description | Published |
20100201579 | USING DIELECTRIC SUBSTRATES, EMBEDDED WITH VERTICAL WIRE STRUCTURES, WITH SLOTLINE AND MICROSTRIP ELEMENTS TO ELIMINATE PARALLEL-PLATE OR SURFACE-WAVE RADIATION IN PRINTED-CIRCUITS, CHIP PACKAGES AND ANTENNAS - Substrate arrangements useful for high-performance radio-frequency planar circuits and antennas eliminate excitation of parallel-plate or surface-wave radiations. By eliminating such radiation which escapes sideways through the substrates, the loss of valuable power carried away by these radiations can be avoided, and/or complications resulting from these radiations (e.g., in the form or electromagnetic interference, cross-talk between circuit components or poor signal integrity) can be avoided. A new type of substrate layer is embedded with thin conducting wires that are closely packed and oriented normal to the substrate layering. These conducting wires change the substrate behavior in a unique way. Such new substrate layers may be used in slotline/coplanar waveguide circuits and microstrip antennas to achieve high-performance radio-frequency operations. | 08-12-2010 |
20100201592 | SLOTTED ANTENNA INCLUDING AN ARTIFICIAL DIELECTRIC SUBSTRATE WITH EMBEDDED PERIODIC CONDUCTING RINGS, FOR ACHIEVING AN IDEALLY-UNIFORM, HEMISPHERICAL RADIATION/RECEPTION WHEN USED AS A SINGLE ANTENNA ELEMENT, OR FOR AZIMUTH(phi)-INDEPENDENT IMPEDANCE-MATCHED ELECTRONIC BEAM SCANNING WHEN USED AS A LARGE ANTENNA ARRAY - A new antenna includes a rectangular slot element provided on a conducting plate and covered by a special substrate portion. The substrate portion includes stacked layers of capacitively-loaded conducting ring elements, arranged in the form of an (e.g., periodic) array in each layer. The slot antenna element is excited by a parallel-plate waveguide, which is fabricated below the conducting plate on which the slot antenna is made. The antenna design, when used in the form of a single antenna element, would produce ideally uniform power radiation over all directions in the upper hemi-spherical space. A large periodic array of such ideally isotropic antenna elements permits electronic beam scanning and has a performance of power coupling from signal sources at the antenna inputs which is independent of the azimuth (Φ) scanning direction, dependent only on one spatial variable (elevation angle, θ) of scanning. Such performance from an antenna array normally can not be achieved using conventional designs. Such an antenna array may be used in communications and radars. | 08-12-2010 |
20100214042 | FREE-SPACE WAVEGUIDES, INCLUDING AN ARRAY OF CAPACITIVELY LOADED CONDUCTING RING ELEMENTS, FOR GUIDING A SIGNAL THROUGH FREE SPACE - A “wireless cable” (also referred to as a “free-space waveguide”), which does not require a continuous body of conducting wire, is provided. Rather, a series of conducting rings, each loaded with a suitable capacitance element, is properly arranged in an empty medium. The distance between the conducting ring elements is of the order of half the wavelength of the signal to be carried, or less. Normally, the series of ring elements would operate as an antenna array, radiating the signal power away from the structure. However, under suitable design conditions, ideally all the signal power can be directed along an axis of the series of conducting ring elements. A signal source can be connected to the ring element at one end of the series, and a suitable electrical load be connected to the element at the opposite end to collect the guided signal power. Additional matching circuits may be provided to properly couple the source and load to the wireless cable. | 08-26-2010 |
20100220009 | AZIMUTH-INDEPENDENT IMPEDANCE-MATCHED ELECTRONIC BEAM SCANNING FROM A LARGE ANTENNA ARRAY INCLUDING ISOTROPIC ANTENNA ELEMENTS - A large periodic array of ideally isotropic antenna elements permits electronic beam scanning and has a performance of power coupling from signal sources at the antenna inputs which is independent of the azimuth (Φ) scanning direction, dependent only on one spatial variable (elevation angle, θ) of scanning Such performance from an antenna array normally can not be achieved using conventional designs. Such an antenna array may be used in communications and radars. | 09-02-2010 |
20130116980 | MODULAR MODELING AND DESIGN OF ANTENNAS AND RADIO FREQUENCY CIRCUITS THAT ARE ARRANGED IN A CLASS OF COMPOSITE STRUCTURAL CONFIGURATIONS - The problem of modeling and designing a structure including a planar element(s) (e.g., antenna, RF circuit, etc.) arranged in association with a non-planar element(s) (e.g., non-planar packaging, a non-planar scattering element, a complex meta material, a periodic array element, etc.), in a computationally efficient and rigorous manner is solved by (1) modeling each of the planar elements using both conventional space-spectral analysis and complex space-spectral analysis to obtain an electro-magnetic (EM) signature matrix for each planar element, (2) determining (e.g., using a brute force modeling based on Maxwell's equations, by measuring experimentally, or by reading one from a stored library) an EM signature matrix (e.g., reflection and scattering matrices) compatible with those of the planar elements, for each of the non-planar elements, and (3) combining the EM signatures of the elements using matrix analysis to obtain a complete EM signature the structure. | 05-09-2013 |
Patent application number | Description | Published |
20090003279 | Method and Apparatus For Dynamically Creating and Updating Base Station Neighbor Lists - The invention includes a method and apparatus for creating a base station neighbor list at a target base station in a wireless network including a plurality of base stations. A method includes obtaining information for creating the base station neighbor list, creating the base station neighbor list using the obtained information, and storing the base station neighbor list. The obtained information includes at least one of geographic locations of ones of the base stations, network status information associated with the wireless network, and pilot signal strength measurement feedback information. The base station neighbor list includes a subset of the base stations of the network. The base stations of the base station neighbor list may be prioritized using at least a portion of the obtained information. The base station neighbor list may be updated periodically, or in response to changes to the obtained information. The base station neighbor list is distributed from the base station to wireless user devices served by the base station for use by the wireless user devices in making handoff decisions. | 01-01-2009 |
20090005052 | Method and Apparatus for Dynamically Creating and Updating Base Station Neighbor Lists - The invention includes a method and apparatus for creating a base station neighbor list for a target base station in a network comprising a plurality of base stations. A method includes obtaining signal strength measurement information associated with a set of candidate base stations, creating the base station neighbor list by selecting ones of the candidate base stations for inclusion in the base station neighbor list in a manner for substantially maximizing a number of locations in the coverage area of the target base station receiving signal coverage from at least a threshold number of selected ones of the candidate base stations, and storing the base station neighbor list. The base station neighbor list may be updated periodically, or in response to changes to signal strength measurement information. The base station neighbor list is distributed from the base station to wireless user devices served by the base station for use by the wireless user devices in making handoff decisions. | 01-01-2009 |
20090005102 | Method and Apparatus for Dynamically Adjusting Base Station Transmit Power - The invention includes a method and apparatus for adjusting the transmit power of a base station. In one embodiment, the transmit power of a base station is adjusted using rate metrics. A method according to one embodiment includes adjusting a transmit power of a target base station based on a per-user rate metric associated with the target base station and at least one per-user rate metric associated with at least one other base station. The per-user rate metrics may be based on any base station metrics, such as average system throughput of the base station, aggregate cell capacity of the base station, and the like. The per-user rate metrics may be computed or estimated using feedback information from wireless user devices. In one embodiment, the transmit power of a base station is adjusted using other information, such as geographic distances between base station, signal strength measurements received at base stations from other base stations, and the like, as well as various combinations thereof. A method according to one embodiment includes obtaining non-feedback information and adjusting the transmit power of the base station using the non-feedback information. | 01-01-2009 |
20120209808 | METHOD AND APPARATUS FOR PEER-TO-PEER DATABASE SYNCHRONIZATION IN DYNAMIC NETWORKS - A distributed database synchronization capability is provided herein. The distributed database synchronization capability may be implemented using one or more of a timer-based scheme and a token-based scheme. The distributed database synchronization capability enables synchronization of databases of nodes in various types of networks, including dynamic networks (e.g., such as rapidly deployable wireless networks) and various other types of networks. The synchronization of databases may include synchronization of databases as a whole and/or portions of databases (which may include any suitable database table or tables). The distributed database synchronization capability enables synchronization of databases of nodes under various dynamic conditions (e.g., synchronization of databases of nodes within a cluster of nodes, synchronization of databases of nodes between clusters of nodes, synchronization of databases of nodes by administrative domain, and the like). | 08-16-2012 |
20120250647 | METHODS OF REVERSE LINK POWER CONTROL - Methods of reverse link power control are provided. A first example method includes first adjusting OFDMA transmission power based on first feedback signals during an OFDMA transmission and second adjusting OFDMA transmission power based on second feedback signals during periods between OFDMA transmissions. A second example method includes sending first power adjustment indicators based on measured OFDMA SINRs when receiving OFDMA transmissions from a mobile station and sending second power adjustment indicators based on estimated OFDMA SINRs when not receiving OFDMA transmissions from the mobile station. A third example method includes receiving a plurality of interference indicating signals from different base stations and determining whether to adjust a maximum transmit power threshold based on the plurality of interference indicating signals, the maximum transmit power threshold indicating the maximum permitted transmission power level below which transmissions are constrained. | 10-04-2012 |
20140219172 | METHODS OF REVERSE LINK POWER CONTROL - Methods of reverse link power control are provided. In one example embodiment, a signal-to-interference+noise (SINR) is measured for a plurality of mobile stations. A power control adjustment is determined for each of the mobile stations based on the measured SINR for the mobile station and a fixed target SINR, the fixed target SINR being used in the determining step for each mobile station and sending the power control adjustments to the mobile stations. In another example embodiment, one or more signals are transmitted to a base station. A power control adjustment indicator indicating an adjustment to a transmission power level is received. The received power control adjustment is determined based on a measured signal-to-interference+noise ratio (SINR) for the one or more transmitted signals and a fixed target SINR threshold, the fixed target SINR threshold being used for power control adjustment of a plurality of mobile stations. | 08-07-2014 |
20140274149 | System and Method for Localizing Wireless Devices - Method and apparatus are provided for localizing wireless devices. In one such arrangement, a method of fingerprinting includes receiving, by a first network element, a plurality of records from a second network element and determining a first segment. A first drive test record of the plurality of records can be assigned to the first segment, and a second segment can be determined, where a first area of the first segment is not equal to a second area of the second segment. A second drive test record of the plurality of records can be assigned to the second segment. | 09-18-2014 |