Darija
Darija Muharemagic, Gatineau CA
Patent application number | Description | Published |
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20140342918 | Method For Affinity Purification - The disclosure relates to a switchable aptamer having a high affinity for a selected target such as a virus, cell or antibody when in the presence of a binding ion and a low affinity for said target in the absence of said binding ion. The switchable aptamer may be isolated from a pool comprising a mixture of aptamers by incubating the pool with the target ligand and a binding ion to form target-aptamer complexes; separating unbound aptamer molecules from the target-aptamer complexes; contacting the target-aptamer complexes with a chelating agent having affinity for the binding ion wherein a switchable aptamer specific to said target is released from the target-aptamer complexes; and isolating the switchable aptamer released in the preceding step. | 11-20-2014 |
Darija Oven, Ljubljana SI
Patent application number | Description | Published |
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20090098605 | MUTATED TRUNCATED mt-pfkA GENE FOR THE SYNTHESIS OF ACTIVE SHORTER FRAGMENT OF 6-PHOSPHOFRUCTO-1-KINASE - The invention deals with mutated truncated mX-pfkA gene encoding shorter fragment of 6-phosphofructo-1-kinase (PFK1), with no need for phosphorylation of the protein molecule for activation, that is not significantly inhibited by citric acid and/or its salts and ATP molecules. Active 49-52 kDa fragment encoded by mt-pfltk gene, retains positive regulatory properties of the native protein and is activated in the presence of specific activators, while citric acid and ATP, important metabolites that function as feed back inhibitors in higher organisms do not reduce its activity. The invention deals with the use of modified shorter fragment in biotechnological processes for fabricating primary and secondary metabolites. | 04-16-2009 |
Darija Susac, Richmond CA
Patent application number | Description | Published |
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20130022890 | SOLID POLYMER ELECTROLYTE FUEL CELL WITH IMPROVED VOLTAGE REVERSAL TOLERANCE - In solid polymer electrolyte fuel cells, an oxygen evolution reaction (OER) catalyst may be incorporated at the anode along with the primary hydrogen oxidation catalyst for purposes of tolerance to voltage reversal. Incorporating this OER catalyst in a layer at the interface between the anode's primary hydrogen oxidation anode catalyst and its gas diffusion layer can provide greatly improved tolerance to voltage reversal for a given amount of OER catalyst. Further, this improvement can be gained without sacrificing cell performance. | 01-24-2013 |