Patent application number | Description | Published |
20090162413 | COMPOSITIONS AND METHODS OF ADMINISTERING RAPAMYCIN ANALOGS WITH PACLITAXEL USING MEDICAL DEVICES - Systems and compositions comprising paclitaxel and a second drug, such as rapamycin, analogs, derivatives, salts and esters thereof are disclosed, as well as methods of delivery wherein the drugs have effects that complement each other. Medical devices comprising supporting structures capable of including or supporting a pharmaceutically acceptable carrier or excipient, which carrier or excipient can contain one or more therapeutic agents or substances, with the carrier preferably including a coating on the surface thereof, and the coating including the therapeutic substances, such as, for example, drugs. Supporting structures for the medical devices that are suitable for use in this invention include coronary stents, peripheral stents, catheters, arterio-venous grafts, by-pass grafts, and drug delivery balloons used in the vasculature. These compositions and systems can be used in combination with other drugs, including anti-proliferative agents, anti-platelet agents, anti-inflammatory agents, anti-thrombotic agents, cytotoxic drugs, agents that inhibit cytokine or chemokine binding, cell de-differentiation inhibitors, anti-lipaedemic agents, matrix metalloproteinase inhibitors, cytostatic drugs, or combinations of these and other drugs. | 06-25-2009 |
20090216317 | Delivery of Highly Lipophilic Agents Via Medical Devices - An apparatus and system for delivering a lipophilic agent associated with a medical device including: a medical device, a first lipophilic agent capable of penetrating a body lumen, wherein the transfer coefficients of the first lipophilic agent is by an amount that is statistically significant of at least approximately 5,000, wherein the first lipophilic agent is associated with the medical device, wherein the first lipophilic agent/medical device is placed adjacent to said body lumen, and wherein a therapeutically effective amount of the first lipophilic agent is delivered to a desired area within a subject. Furthermore, the invention relates to a method for improving patency in a subject involving placement of a medical device in a body lumen for treating and/or preventing adjacent diseases or maintaining patency of the body lumen. | 08-27-2009 |
20100082095 | Coatings Including Dexamethasone Derivatives And Analogs And Olimus Drugs - The present invention encompasses a coating on the surface of a substrate and the coated substrates. The coating includes a polymer, an olimus drug (sirolimus, everolimus, zotarolimus, etc.), and a dexamethasone derivative. The polymer may be a hydrophobic polymer, preferably a fluoropolymer, and more preferably a fluoropolymer with at least 25% vinylidene fluoride by weight. | 04-01-2010 |
20110137243 | Coating On A Balloon Device - The present invention provides a hygroscopic coating on a balloon for an implantable device and methods of making and using the same. | 06-09-2011 |
20130013048 | MULTIPLE DRUG DELIVERY FROM A BALLOON AND A PROSTHESIS - Disclosed is an interventional device for delivery of therapeutic agents from an angioplasty balloon and from a prosthesis such as an intraluminal stent. The invention also relates to the method of loading the beneficial agents onto the balloon and the device, as well as the method of delivery of the agents from separate surfaces. The invention also relates to an interventional device having a prosthesis surface that is loaded with a first beneficial agent, and a balloon surface loaded with a second beneficial agent. The invention also relates to a method of loading multiple beneficial agents onto the prosthesis surfaces and the balloon surfaces, and to a method of manufacturing an interventional device for the delivery of a first beneficial agent and a second beneficial agent from separate surfaces. | 01-10-2013 |
Patent application number | Description | Published |
20090306981 | Systems and methods for conversation enhancement - This invention description details systems and methods for improving human conversations by enhancing conversation participants' ability to: —Distill out and record core ideas of conversations. —Classify and prioritize these key concepts. —Recollect commitments and issues and take appropriate action. —Analyze and uncover new insight from the linkage of these ideas with those from other conversations. | 12-10-2009 |
20090319265 | Method and system for efficient pacing of speech for transription - A method and system for improving the efficiency of real-time and non-real-time speech transcription by machine speech recognizers, human dictation typists, and human voicewriters using speech recognizers. In particular, the pacing with which recorded speech is presented to transcriptionists is automatically adjusted by monitoring the transcriptionists' output by comparing the output acoustically or phonetically to the presented recorded speech as well as monitoring the resulting transcription, and accordingly adjusting the pacing. | 12-24-2009 |
20110087491 | Method and system for efficient management of speech transcribers - A method and system for improving the efficiency of speech transcription by automating the management of a varying pool of human and machine transcribers having diverse qualifications, skills, and reliability for a fluctuating load of speech transcription tasks of diverse requirements such as accuracy, promptness, privacy, and security, from sources of diverse characteristics such as language, dialect, accent, speech style, voice type, vocabulary, audio quality, and duration. | 04-14-2011 |