Coy
Francisco Pubill Coy, Barcelona ES
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20090169560 | DISULFIDE, SULFIDE, SULFOXIDE, AND SULFONE DERIVATIVES OF CYCLIC SUGARS AND USES THEREOF - In the present invention there are disclosed new derivatives of dianhydrohexite mononitrate corresponding to formula (I), tautomers, pharmaceutically acceptable salts, prodrugs and solvates thereof: | 07-02-2009 |
20100160652 | STEREOSPECIFIC METHOD FOR THE PREPARATION OF DIOXA-BICYCLOOCTANE NITRATE COMPOUNDS - This invention relates to a new method for the stereospecific thiocarboxylation and nitration of organic compounds for the preparation of compounds according to formula (I): | 06-24-2010 |
20100196387 | Disulfide, Sulfide, Sulfoxide, and Sulfone Derivatives of Cyclic Sugars and Uses Thereof - In the present invention there are disclosed new derivatives of dianhydrohexite mononitrate corresponding to formula (I), tautomers, pharmaceutically acceptable salts, prodrugs and solvates thereof: | 08-05-2010 |
20110251409 | STEREOSPECIFIC METHOD FOR THE PREPARATION OF DIOXA-BICYCLOOCTANE NITRATE COMPOUNDS - This invention relates to a new method for the stereospecific thiocarboxylation and nitration of organic compounds for the preparation of compounds according to formula (I): | 10-13-2011 |
20130046012 | NEW COMPOUNDS, SYNTHESIS AND USE THEREOF IN THE TREATMENT OF PAIN - The present invention relates to compounds of formula (I), or pharmaceutically acceptable, stereoisomers, salts or solvates thereof | 02-21-2013 |
Johannes Coy, Dossenheim DE
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20080234393 | COMPOUNDS AND METHODS FOR DETECTION OF CARCINOMAS AND THEIR PRECURSOR LESIONS - The present invention relates to compounds and methods for detection and treatment of carcinomas and their precursor lesions. The invention provides DNase nucleic acids and polypeptides useful for the detection and treatment of carcinomas and their precursor lesions. The invention is more specifically related to a method for detection of carcinomas and their precursor lesions comprising the detection of the level and/or the subcellular localization of one or more DNase molecules in biological samples. Furthermore the present invention provides methods for early diagnosis, prognosis and monitoring of the disease course of carcinomas and their precursor lesions as well as for the treatment of said lesions. | 09-25-2008 |
20090098544 | MARKER MOLECULES ASSOCIATED WITH LUNG TUMORS - The present invention relates to nucleic acids and polypeptides associated with lung cancer. The invention is more specifically related to a nucleic acids and the polypeptides transcribed thereof, the expression of which is significantly altered in association with lung cancer. The invention relates to a series of differentially spliced transcripts of the gene disclosed herein, that are associated with tumors of the respiratory tract. Furthermore the present invention provides a method for early diagnosis, prognosis and monitoring of the disease course and for therapy and vaccination of cell proliferative disorders such as e.g. lung tumors. | 04-16-2009 |
Johannes Coy, Grossostheim DE
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20100136577 | COMPOSITIONS AND METHODS FOR DETECTION AND TREATMENT OF PROLIFERATIVE ABNORMALITIES ASSOCIATED WITH OVEREXPRESSION OF HUMAN TRANSKETOLASE LIKE-1 GENE - Methods for in vitro diagnosis of carcinoma are disclosed. In one aspect the invention relates to methods such as detecting the level of transketolase like-1 polypeptide, which are especially useful for the detection of tumors and their precursory stages based on the detection of overexpression of human transketolase like-1 gene in biological samples. In another aspect the invention relates to methods for treatment of disorders associated with the overexpression of human transketolase like-1 gene. Methods for treatment may include gene therapeutic approaches as well as methods for inhibiting or reducing the activity of transketolase like-1 polypeptides. | 06-03-2010 |
Johannes Coy, Otzberg DE
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20080233263 | Beverage - The present invention provides a beverage, comprising: 5-35% weight/volume fat and/or oil, wherein the fat/oil comprises vegetable oils, and comprises a maximum of 30% weight/volume saturated fatty acids and minimum 20% weight/volume unsaturated fatty acids, said unsaturated fatty acids comprising omega-3-fatty acids and omega-6-fatty acids, and the weight ratio of said omega-6 fatty acids to said omega-3 fatty acids is no greater than 4:1; a maximum of 2.5% weight/volume of carbohydrates; and lactic acid; wherein the content of fat and/or oil is higher than the carbohydrate content by weight. The beverage is especially suitable for patients suffering from inflammatory diseases (Ulcerative Colitis, Rheuma, Multiple Sclerosis), from diabetes and associated chronic diabetes complications (retinopahty, neuropathy, nephropathy, micro- and macrovascular damages e.g. blood vessel damages, myocardial infarction), from neurodegenerative diseases (Alzheimer's, Wernicke-Korsakoff syndrome), and from cancer. | 09-25-2008 |
20100240687 | METHOD FOR CHECKING AND CONTROLLING THE MAMMALIAN LACTIC ACID FERMENTATION PROCESS/AEROBIC GLUCOSE FERMENTATION METABOLIC PATHWAY IN MAMMALIAN ORGANISM - The method for qualitative and quantitative detecting of the extend of use and the correct process flow of the mammalian aerobic glucose fermentation metabolic pathway (mam-aGF) in a mammalian individual is characterized in that the enzyme TKTL1 is used as indicator and target molecule and the structural and/or functional parameter of said TKTL1 in a biological sample of said individual (patient) are taken as indication for the qualitative and quantitative run of the mam-aGF in the cells and/or tissue of said individual (patient). In combination with the use of inhibitors and activators of the mam-aGF the method is further suitable for checking and controlling the mam-aGF in an individual (patient). | 09-23-2010 |
Johannes Coy, Hainburg DE
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20130280357 | CHOCOLATE MASS - The invention provides a novel chocolate mass which has a glycemic index of less than 29 (GI<29) and of which the content of added sugar comprises at least 10% galactose and in addition a content of iosmaltulose and/or tagatose. The chocolate mass additionally has a content of vitamin E in the form of a tocotrienol-tocopherol mixture from natural sources, wherein the content of tocotrienols in the chocolate mass is greater than the content of tocopherols. | 10-24-2013 |
20130287871 | REFRESHING BEVERAGE - The invention relates to a novel sweet-tasting refreshing beverage, which is free of phosphoric acid and instead contains at least 0.3% by weight/volume of gluconic acid, which is low in minerals, specifically contains less than 250 mg/liter of minerals, which is low in sugar, specifically contains at most 2.5% by weight/volume of sugar, wherein these sugars comprise at least 10% weight/weight galactose and in addition a proportion of isomaltulose and/or tagatose, and which has a glycemic index of at most 35 (GI<35). | 10-31-2013 |
Johannes C Coy, Hainburg DE
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20160084828 | AUTOMATABLE METHOD FOR THE IDENTIFICATION, QUANTIFICATION AND DISCRIMINATION OF SPECIFIC SIGNALS IN RELATION TO NON-SPECIFIC SIGNALS IN DETECTION METHODS BY MEANS OF A DETECTOR - The invention relates to an automatable method for the identification, quantification and discrimination of specific signals in relation to non-specific signals in detection methods by means of a detector emitting or generating signals, in which at least one control approach is carried out in parallel to the actual test approach, which contains all the components of the actual test approach but in which the binding domain(s) of the detector is/are blocked. The analytical measurements of the signals of the control approach and of the actual test approach are compared with each other and the signal of the specifically bound detector in the test approach is calculated therefrom. | 03-24-2016 |
Johannes F. Coy, Grossostheim DE
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20090221525 | FUNCTIONAL FOODS AGAINST TUMORS - The present invention relates to the technical field of functional foods, more precisely novel functional foods for the treatment and/or prevention of malignant carcinomas of the human or animal body, and also to processes for producing such functional foods. | 09-03-2009 |
Johannes F. Coy, Otzberg DE
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20090311351 | COMPOSITION CONTAINING A CEREAL MILLING PRODUCT - The invention relates to a composition, in particular a bread, containing a cereal milling product, wherein the composition has a carbohydrate fraction of less than 15% by weight and an omega-3 fatty acid content of at least 2% by weight. | 12-17-2009 |