Colman
Alan Colman, Edinburgh GB
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20080250517 | Methods - The production of genetically modified animals, in which the genetic modifications are engineered in somatic cells cultured in vitro by gene targeting, is described. Genetically modified cells may then used as nuclear donors to produce, inter alia, live animals. The methods described can also be used to validate loci in animal chromosomes which are suitable sites for transgene addition to cells. | 10-09-2008 |
Arne Benjamin Colman, Newark GB
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20090152281 | Container with a device to prevent clogging of a dispensing device of the container - For a container ( | 06-18-2009 |
Arne Benjamin Colman, Balham GB
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20100032443 | Dispenser for providing warm wipes - A wipes dispenser enabling the dispensing on-demand of one or more warm wet wipes. The dispenser may comprise three containers, at least one dosing device, and dispensing devices. | 02-11-2010 |
David R. Colman, Westmount CA
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20100310451 | ALTERED N-CADHERIN PROCESSING IN TUMOR CELLS BY FURIN AND PROPROTEIN CONVERTASE 5A (PC5A) - The present invention relates to a method for diagnosis and/or prognosis of cancer and for monitoring the progression of cancer and/or the therapeutic efficacy of an anti-cancer treatment in a subject by determining the molecular form of cadherin at the cell surface of cancer cells in the subject. The invention also relates to a method for preventing, inhibiting or treating cancer or its metastasis in a subject by increasing the adhesive forms of cadherin and/or decreasing the non-adhesive forms of cadherin at the cell surface. The invention also relates to a method step of determining the expression level of furin and proprotein convertase 5A (PC5A). | 12-09-2010 |
20130184173 | BIOMARKERS FOR MULTIPLE SCLEROSIS - Biomarkers that can be used for the diagnosis and prognosis of multiple sclerosis in pediatric patients presenting with clinically isolated syndrome or acquired demyelination syndrome are described. | 07-18-2013 |
Derek Colman, Bedfordshire GB
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20080212607 | Data Transfer Circuit - A data transfer circuit is provided for sending digital data at high rates across short but significant distances within an integrated circuit. The data is sent on parallel conductors that are divided into a number of groups. At the receiving end, a multiplexer selects each of the groups in turn and presents them at a set of conductors that are the same in number as one of the groups. At the transmitting end, a data marshalling circuit takes the bitstream to be transmitted and places it on the conductors in a particular redundant fashion so that the bitstream appears to advance across the set of outputs of the multiplexer. That is particularly useful where those outputs are presented to a pre-emphasis filter and line driver. The apparent data rate can be changed by making two or more of the groups of conductors have identical data. | 09-04-2008 |
Derek A. Colman, Fleet GB
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20120138698 | Nozzle for Use in Fluidized Catalytic Cracking - Disclosed herein is a nozzle tip that atomizes a liquid entering a vessel or reaction zone that contains circulating fluidized particulates where the nozzle tip comprises a first elongated slot that intersects with a second elongated slot to define a single orifice. The first elongated slot may have members protruding into it and the slots may intersect substantially orthogonally and bisect each other. The length of the minor axis of the first slot ranges form about 5% to about 50% of the length of the major axis of the first slot and the length of the minor axis of the second slot ranges form about 1% to about 10% or the major axis of the second slot. This nozzle tip affords erosion reduction caused by the circulating fluidized particulates and therefore provides longer operational lifetimes for the nozzle tip. | 06-07-2012 |
Derek Alan Colman, Hampshire GB
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20090053117 | Quench Tube, Apparatus and Process For Catalytic Gas Phase Reactions - The present invention relates to a quench tube, having a length (L), a diameter (D) and at least one guenchant inlet per tube which inlet passes guenchant into the tube from the side of said tube, and wherein, D is between 0.04 and 0.10 m and L/D is at least 5. The present invention also relates to an apparatus with one or more of said quench tubes wherein said apparatus comprises a catalyst zone which may have a cross sectional area of at least 0, 01 m2. In processes using said tubes and/or said apparatuses a first gaseous reactant stream and a second reactant stream are contacted with a catalyst to produce a product stream which is quenched on exiting the catalyst. A process for producing olefins by autothermal cracking is also claimed. | 02-26-2009 |
Eefje Colman, Lierde BE
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20120179657 | HUMAN RESOURCES MANAGEMENT SYSTEM AND METHOD INCLUDING PERSONNEL CHANGE REQUEST PROCESSING - A method for processing personnel change requests (PCRs), the method including: identifying a wizard configured for a particular PCR of the PCRs, the PCR having multiple steps; invoking the wizard for guiding a user through first ones of the steps, the first ones of the steps prompting the user for a first set of data associated with the PCR; storing the first set of data in a temporary storage device; invoking the wizard for guiding another user through second ones of the steps, the second ones of the steps prompting the another user for a second set of data associated with the PCR; storing the second set of data in the temporary storage device; monitoring a status of the PCR; and transferring the first and second sets of data from the temporary storage device to a database in response to detecting a particular status of the PCR. | 07-12-2012 |
20120179711 | System and Method for Accessing a Database Including Data Abstraction Layer and Request Table Processing - A method for processing changes to a database, the method including: receiving a request to alter data stored in the database, the request including data being entered in one or more steps wherein each of the steps displays one or more data fields associated with the step; generating a plurality of records based on the received request, wherein the records reflect a particular grouping of the data fields configured to abstract a data model used by the database; temporarily storing the plurality of records in a table; determining whether the request should be processed to alter the data stored in the database; and in response to the determination, modifying the data stored in the database in accordance with the plurality of records stored in the table. | 07-12-2012 |
Joshua Lewis Colman, Jersualem IL
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20130204099 | MEDICAL SYSTEM, APPARATUS AND METHOD - According to some embodiments, there is provided a medical monitoring device that includes one or more sensors, wherein a sensor is adapted to sense a parameter of a patient and computator adapted to receive an output of at least one sensor and to compute a condition-index-value directly related to a condition of the patient. | 08-08-2013 |
Nathaniel Colman, Newport GB
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20140287084 | BRACKET FOR CLAMPING A WIND TURBINE BLADE MOULD TO A SUPPORTING STRUCTURE - A bracket is described for clamping a mould to a supporting structure. The bracket includes a first part and a second part for attaching to the mould and to the supporting structure, respectively, or vice versa. The first and second parts are connected together and configured to provide constrained relative movement along a first axis to accommodate thermal expansion of the mould relative to the supporting structure in a first direction parallel to the first axis. The first and second parts of the bracket are connected via an articulated joint that allows the first and second parts to pivot relative to one another without moving the first axis such that the bracket can independently accommodate misalignments between the mould and the supporting structure. | 09-25-2014 |
Peter Colman, East Melbourne AU
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20100190782 | COMPOUNDS AND METHODS OF USE - In one aspect, the present invention provides for a compound of Formula I | 07-29-2010 |
20100210622 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE - In one aspect, the present invention provides for a compound of Formula I | 08-19-2010 |
20120184541 | COMPOUNDS AND METHODS OF USE - In one aspect, the present invention provides for a compound of Formula I | 07-19-2012 |
20140005190 | COMPOUNDS AND METHODS OF USE | 01-02-2014 |
Peter Malcolm Colman, East Melbourne AU
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20090048164 | THERAPEUTIC PRO-APOPTOTIC BH3-LIKE MOLECULES AND METHODS FOR GENERATING AND/OR SELECTING THE SAME - The present invention relates generally to therapeutic molecules which are useful for modulating apoptosis in a target cell or cell population. More particularly, the present invention provides therapeutic agents which inhibit pro-survival molecules and which are capable of inducing or facilitating apoptosis of a target cell or cell population such as cancer cells. The present invention further provides methods for generating or selecting the therapeutic molecules and pharmaceutical compositions comprising the therapeutic molecules. | 02-19-2009 |
20140066621 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES - Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein. | 03-06-2014 |
Peter Malcolm Colman, Victoria AU
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20100197711 | BENZOTHIAZOLE COMPOUNDS - The present invention relates to benzothiazole compounds that mimic the activity of BH3 only proteins and are capable of binding to and neutralizing pro survival Bcl 2 proteins. The invention also relates to the use of such compounds in the regulation of cell death or cell survival and the treatment and/or prophylaxis of diseases or conditions associated with the deregulation of cell death or cell survival. | 08-05-2010 |