Patent application number | Description | Published |
20150192154 | TORSIONAL MEMBERS AND METHODS OF MAKING AND USING THE SAME - A number of variations may include a torsional member and method of manufacture thereof wherein the torsional member may be fabricated from a core, a shell, and a bonding agent, wherein at least one of the shell or the core comprises a pultruded material comprising carbon. | 07-09-2015 |
20150239205 | COMPOSITE MATERIAL AND METHODS OF MAKING AND USING THE SAME - A number of variations may include a composite material and method of manufacture thereof wherein the composite material may be fabricated from a core, a weave, a fiber and a bonding agent, wherein the weave may be positioned between the core and the fiber. | 08-27-2015 |
20150239208 | COMPOSITE FOAM MATERIAL AND METHOD OF MAKING AND USING THE SAME - A number of variations may include a composite material and method of manufacture thereof wherein the composite material may be fabricated from a first core, a second core comprising foam, a bonding agent, and a skin, wherein the skin at least partially overlays the first core and the second core. | 08-27-2015 |
Patent application number | Description | Published |
20090005304 | Human KCNQ5 potassium channel, methods and compositions thereof - An isolated polynucleotide encoding a novel potassium channel polypeptide, KCNQ5, that is expressed primarily in brain and skeletal muscle is described. The new polypeptide has been cloned and isolated from a human brain cDNA library and is a member the KCNQ family of potassium channels. The provided human KCNQ5 nucleic acid sequence and encoded polypeptide can be employed for diagnostic, screening and therapeutic uses. Moreover, the hKCNQ5 polypeptide can be used to assay for KCNQ5 potassium channel modulators, which can be utilized in the treatment of neurological, neurophysiological, neuropsychological and neuroaffective diseases, conditions and disorders, including, but not limited to, acute and chronic pain, migraine, acute stroke, dementia, vascular dementia, trauma, epilepsy, amyelotrophic lateral sclerosis (ALS), multiple sclerosis (MS), Parkinson's Disease, learning and cognitive disorders, and neurophysiological disorders including anxiety disorders, depression, bipolar disorders, sleep disorders, addiction, and eating disorders. | 01-01-2009 |
Patent application number | Description | Published |
20130189602 | MICROSTRUCTURED ELECTRODE STRUCTURES - A structure for use in an energy storage device, the structure comprising a backbone system extending generally perpendicularly from a reference plane, and a population of microstructured anodically active material layers supported by the lateral surfaces of the backbones, each of the microstructured anodically active material layers having a void volume fraction of at least 0.1 and a thickness of at least 1 micrometer. | 07-25-2013 |
20140050969 | ELECTRODE STRUCTURES FOR THREE-DIMENSIONAL BATTERIES - An electrode structure for use in an energy storage device comprising a population of electrodes, a population of counter-electrodes and a microporous separator separating members of the electrode population from members of the counter-electrode population. Each member of the electrode population comprises an electrode active material layer and an electrode current conductor layer, and each member of the electrode population has a bottom, a top, a length L | 02-20-2014 |
20140329132 | MICROSTRUCTURED ELECTRODE STRUCTURES - A structure for use in an energy storage device, the structure comprising a backbone system extending generally perpendicularly from a reference plane, and a population of microstructured anodically active material layers supported by the lateral surfaces of the backbones, each of the microstructured anodically active material layers having a void volume fraction of at least 0.1 and a thickness of at least 1 micrometer. | 11-06-2014 |
Patent application number | Description | Published |
20100293522 | Developing a Graphical Data Flow Program With Multiple Models of Computation in a Web Browser - System and method for performing program-related operations over a network via a web browser. A network connection is established between a server computer and a client computer over a network. A universal resource identifier (URI) is sent from the client computer to the server computer over the network, where the URI indicates a program, e.g., a graphical program (GP), or at least a portion of a graphical program interactive development environment (GPIDE), e.g., a graphical program editor, an execution engine, a static or dynamic analyzer, and/or compiler. The at least a portion of the GPIDE is received from the server computer over the network in response to the URI, and executed in a web browser of the client computer to perform some specified functionality with respect to the GP. | 11-18-2010 |
20100293525 | Client Side Web Hosted Program Development Environment - System and method for performing program-related operations over a network via a web browser. A network connection is established between a server computer and a client computer over a network. A universal resource identifier (URI) is sent from the client computer to the server computer over the network, where the URI indicates a program, e.g., a graphical program (GP), or at least a portion of a graphical program interactive development environment (GPIDE), e.g., a graphical program editor, an execution engine, a static or dynamic analyzer, and/or compiler. The at least a portion of the GPIDE is received from the server computer over the network in response to the URI, and executed in a web browser of the client computer to perform some specified functionality with respect to the GP. | 11-18-2010 |
20110225524 | Multi-Touch Editing in a Graphical Programming Language - System and method for editing a graphical program. A graphical program is displayed on a display device. Multi-touch input is received to a multi-touch interface, where the multi-touch input specifies an edit operation in the graphical program. The edit operation is performed in the graphical program in response to the multi-touch input, and the edited graphical program is displayed on the display device. | 09-15-2011 |
20120089935 | Mixed Signal Analysis - System and method implementing an integrated interface for multiple instruments for signal analysis, including two or more virtual instruments. The method includes a) receiving user input specifying an operation implementing at least a portion of a signal analysis function; b) performing the operation utilizing at least one of the instruments to perform the operation; c) displaying an icon comprising a graphical representation of the operation in response to the specifying; d) storing information specifying the operation; and repeating a)-d) multiple times to specify the function, thereby producing stored information representing the operations in the function, and after which multiple icons are displayed representing the operations and visually indicating the function. The operations in the function include 1) generating signals displayed in a graph, and/or 2) modifying one or more signals displayed in the graph. After each respective operation is specified, the operation is performed substantially continuously during said repeating. | 04-12-2012 |
20130031501 | Weighted Zoom within a Diagram of a System - Providing zooming within a system diagram. Initially, a diagram of a system may be displayed. The diagram may include a plurality of icons representing physical components of the system. These plurality of icons may be initially displayed at a first level of magnification. User input to zoom on a first physical component in the diagram may be received. Accordingly, the first physical component may be displayed at a second level of magnification and other ones of the physical components may be displayed at a third level of magnification. The second level of magnification may be greater than the first level of magnification and the third level of magnification may be less than the first level of magnification. Alternatively, or additionally, different representations for various components of the system may be displayed in the diagram during or after the zoom. | 01-31-2013 |
20130031508 | Semantic Zoom within a Diagram of a System - Providing zooming within a system diagram. Initially, a diagram of a system may be displayed. The diagram may include a plurality of icons representing physical components of the system. These plurality of icons may be initially displayed at a first level of magnification. User input to zoom on a first physical component in the diagram may be received. Accordingly, the first physical component may be displayed at a second level of magnification and other ones of the physical components may be displayed at a third level of magnification. The second level of magnification may be greater than the first level of magnification and the third level of magnification may be less than the first level of magnification. Alternatively, or additionally, different representations for various components of the system may be displayed in the diagram during or after the zoom. | 01-31-2013 |
20130145312 | Wiring Method for a Graphical Programming System on a Touch-Based Mobile Device - A touch-gesture wiring method for connecting data flow wires to input/output terminals of nodes in a graphical program is described. The method may be implemented by a graphical programming application that executes on a mobile device that includes a touch-sensitive screen configured to receive user input as touch gestures. The method may aid the user by displaying a magnified view of the input/output terminals that makes it easier (relative to the default view of the graphical program) for the user to see the input/output terminals and/or easier to select a desired one of the input/output terminals. | 06-06-2013 |
20140109044 | Multi-Touch Editing in a Graphical Programming Language - System and method for editing a graphical program. A graphical program is displayed on a display device. Multi-touch input is received to a multi-touch interface, where the multi-touch input specifies an edit operation in the graphical program. The edit operation is performed in the graphical program in response to the multi-touch input, and the edited graphical program is displayed on the display device. | 04-17-2014 |
Patent application number | Description | Published |
20090306186 | NOVEL TISSUE PROTECTIVE ERYTHROPOIETIN RECEPTOR (NEPOR) AND METHODS OF USE - There is disclosed a molecular composition(s) of a novel tissue protective erythropoietin (EPO) binding receptor protein complex, termed NEPOR. Presence of NEPOR components on a tumour allows EPO to impinge on the survival of associated cells thereby enhancing tumour progression and negatively effecting patient survival. Presence of NEPOR represents a prognostic biomarker for poorer patient outcome. Thus, methods are provided for stratifying patients having a tumour as suitable (i.e. NEPOR not present) or non-suitable (i.e., NEPOR present) for EPO treatment, comprising: (a) isolating a tissue sample from an individual who is receiving or is a candidate for receiving erythropoietin, (b) determining the level of expression of the NEPOR gene(s) (mRNA) and/or the presence of the NEPOR gene product (protein) from the isolated tissue, and (c) correlating the presence of an NEPOR gene expression product or the presence of NEPOR protein to a physiological response to the treatment with erythropoietin. Furthermore, by disclosing the molecular compositions of NEPOR species, there are disclosed methods for rationally identifying/designing NEPOR modulating therapeutics. Methods also are provided for treating neurological insults such as stroke (via enhancement of NEPOR activity) and cancer (via down-regulation of cyto-protective signaling from NEPOR). | 12-10-2009 |
20120245087 | NOVEL TISSUE PROTECTIVE ERYTHROPOIETIN RECEPTOR (NEPOR) AND METHODS OF USE - There is disclosed a molecular composition(s) of a novel tissue protective erythropoietin (EPO) binding receptor protein complex, termed NEPOR. Presence of NEPOR components on a tumour allows EPO to impinge on the survival of associated cells thereby enhancing tumour progression and negatively effecting patient survival. Presence of NEPOR represents a prognostic biomarker for poorer patient outcome. Thus, methods are provided for stratifying patients having a tumour as suitable (i.e. NEPOR not present) or non-suitable (i.e., NEPOR present) for EPO treatment, comprising: (a) isolating a tissue sample from an individual who is receiving or is a candidate for receiving erythropoietin, (b) determining the level of expression of the NEPOR gene(s) (mRNA) and/or the presence of the NEPOR gene product (protein) from the isolated tissue, and (c) correlating the presence of an NEPOR gene expression product or the presence of NEPOR protein to a physiological response to the treatment with erythropoietin. Furthermore, by disclosing the molecular compositions of NEPOR species, there are disclosed methods for rationally identifying/designing NEPOR modulating therapeutics. Methods also are provided for treating neurological insults such as stroke (via enhancement of NEPOR activity) and cancer (via down-regulation of cyto-protective signaling from NEPOR). | 09-27-2012 |
Patent application number | Description | Published |
20120116967 | Mobile payment system and method - System, method, and computer program product are provided for a user to send and receive P2P payments using a mobile device. Through the use of the mobile device, a user may access his/her accounts at a financial institution and direct payments to a third-party using an alias. The user may ensure a secure payment to a third-party through the network associated with a financial institution. Payments may be directed to individuals the user may input into the system by providing the individual's alias. An alias may be a unique identifier of an individual and tied to a financial account of that individual. The sender of the P2P payments may input the recipient's alias and transfer funds via the P2P payment system without having to input the recipient's account information. This invention allows a user to receive and provide payments for transactions utilizing the convenience of a mobile device. | 05-10-2012 |
20120116973 | Online payment system and method - System, method, and computer program product are provided for a user to send and receive P2P payments using the Internet. Through the use of a network, a user may access accounts the user has at a financial institution and direct payments to other individuals or entities using the other individuals or entities alias. In this way, the user may ensure a secure payment to a third-party through the network associated with a financial institution. The payments may be directed to individuals the user may input into the system by providing the user's alias. A user's alias may be a unique identifier of the user and tied to a financial account of that user. In this way, the sender of the P2P payments may input the recipient's alias and transfer funds via the P2P payment system without having to input the recipient's account information. | 05-10-2012 |
20140222681 | ONLINE PAYMENT SYSTEM AND METHOD - System, method, and computer program product are provided for a user to send and receive P2P payments using the Internet. Through the use of a network, a user may access accounts the user has at a financial institution and direct payments to other individuals or entities using the other individuals or entities alias. In this way, the user may ensure a secure payment to a third-party through the network associated with a financial institution. The payments may be directed to individuals the user may input into the system by providing the user's alias. A user's alias may be a unique identifier of the user and tied to a financial account of that user. In this way, the sender of the P2P payments may input the recipient's alias and transfer funds via the P2P payment system without having to input the recipient's account information. | 08-07-2014 |
Patent application number | Description | Published |
20130220282 | TURBOCHARGED ENGINE CANISTER SYSTEM AND DIAGNOSTIC METHOD - An evaporative emission control system for a turbocharged engine. The system includes a fuel vapor canister in fluid communication with an intake manifold of the engine, a purge valve positioned between the intake manifold and the canister, a bypass valve positioned between the purge valve and the canister and connected to the atmosphere, and an evaporative system integrity monitor operable to seal the canister from the atmosphere when the engine is off. In operation, the monitor is closed so as to seal the canister from the atmosphere, the purge valve is closed so as to isolate the intake manifold from the canister, and the bypass valve is opened so as to connect the canister to the atmosphere. Proper operation of the monitor is determined if the monitor toggles from closed to open when a vacuum in the fuel vapor canister reaches a predetermined level. | 08-29-2013 |
20130282230 | TURBO-CHARGED ENGINE PURGE FLOW MONITOR DIAGNOSTIC - A method for testing the evaporative emission system of a vehicle. The method provides for testing the evaporative emission system of a vehicle having a forced induction engine. The method includes controlling a vacuum bypass valve and a purge flow control valve to create the necessary conditions to perform the testing of the evaporative emission system. | 10-24-2013 |
20140365071 | TURBOCHARGED ENGINE PURGE FLOW MONITOR DIAGNOSTIC - A method is provided for testing the evaporative emission system of a vehicle having a forced induction engine. The method includes controlling a vacuum bypass valve and a purge flow control valve to create the necessary conditions to perform the testing of the evaporative emission system. The method determines whether an evaporative system integrity monitor switch is open after a timer is initiated and the vacuum bypass valve is opened. | 12-11-2014 |
20150096541 | BOOST PURGE EJECTOR TEE ARRANGEMENT - A boost purge ejector tee arrangement for a fuel vapor emissions system can include a boost purge ejector tee having a body that can define a first inlet port, a second inlet port and an outlet port. The first inlet port and the outlet port can be fluidly coupled along a first flow path. The body can define a second flow path from the second inlet port that can intersect the first flow path upstream of the outlet port. A nozzle can be positioned in the first flow path such that an outlet of the nozzle can be proximate the intersection of the second flow path with the first flow path. The boost purge ejector tee can be integrated into an air box that can be associated with an engine such that the outlet port exits into an inside of the air box. | 04-09-2015 |
Patent application number | Description | Published |
20080313254 | VIRTUAL FIELDBUS DEVICE - A virtual fieldbus device module is a software or firmware module that enables an otherwise ordinary fieldbus device to become a complex fieldbus device, capable of registering and maintaining multiple fieldbus network addresses for one or more “virtual” fieldbus devices. Each virtual fieldbus device has one or more sensor inputs and appears to the fieldbus network as an individual physical fieldbus device, despite the complex fieldbus device only having one physical connection to the fieldbus network. The virtual fieldbus device module may be incorporated into a device's firmware or may be included in a memory plug-in capable of being removed. The communication packet processing of a complex fieldbus device running the virtual fieldbus device module includes receiving a communication packet over the fieldbus network, determining whether the address associated with the packet matches any of the addresses registered by the complex fieldbus device, and processing any packets that match. | 12-18-2008 |
20090070387 | METHOD AND APPARATUS FOR AUTOMATED STORAGE OF EVENT-SUBSTANTIATING DATA - A method for detecting an event and/or behavior of interest based on monitoring data and selectively storing portions of the monitoring data associated with the event and/or behavior of interest. Preferably, the method includes defining a hierarchy of event and/or behavior types so that the storing of a first behavior/event type is preferred over a second behavior/event type, especially when storing capacity is scarce. A data management apparatus including a logic device and a long-term storage memory apparatus, the logic device for detecting an event and/or behavior of interest based on monitoring data and selectively storing portions of the monitoring data associated with the event and/or behavior of interest on the long-term memory storage apparatus. | 03-12-2009 |
20160048110 | Adaptive And State Driven Data Collection - A method of automatically adjusting data collection parameters for machines on a data collection route in a portable collection device used by a technician, based on states of the machines. For each machine on the data collection route, the state of the machine is read into the portable collection device. The machine is automatically included in or excluded from the data collection route based at least in part on the state of the machine. The portable collection device is automatically configured with a first predetermined set of data collection parameters that is automatically configured based at least in part on the state of the included machine. An initial set of data is collected from the included machine with the portable collection device, based on the first predetermined set of data collection parameters. The initial set of data is automatically analyzed using a predetermined set of data analysis parameters that is automatically configured based at least in part on the state of the included machine, to determine alerts. Based on the alerts, a second set of data is selectively automatically immediately collected from the included machine based on a second predetermined set of data collection parameters that is automatically configured based at least in part on the state of the included machine and the alerts. Also based on the alerts, the technician is selectively prompted with the portable collection device to take a predetermined action and collect a third set of data from the included machine. The action and the third set of data is based on a third predetermined set of data collection parameters that is automatically configured at least in part on the state of the included machine and the alerts. | 02-18-2016 |
Patent application number | Description | Published |
20130203681 | Macrocyclic Compounds Useful as Inhibitors of Histone Deacetylases - The present invention provides a novel macrocyclic compound of general Formula (I) having histone deacetylase (HDAC) inhibitory activity, a pharmaceutical composition comprising the compound, and a method useful to treat diseases using the compound. | 08-08-2013 |
20140288123 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF - Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein. | 09-25-2014 |
20140315949 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF - Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein. | 10-23-2014 |
20140371206 | BROMODOMAIN INHIBITORS AND USES THEREOF - The present invention relates to compounds useful as inhibitors of bromodomain-containing proteins. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various disorders. | 12-18-2014 |
20150259351 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF - Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein. | 09-17-2015 |
20150315148 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF - Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein. | 11-05-2015 |
20150368229 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF - Agents for modulating methyl modifying enzymes, compositions and uses thereof are provided herein. | 12-24-2015 |
20150376190 | MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF - Agents having the structural Formula (II) for modulating histone methyl modifying enzymes, compositions and uses thereof for instance as anti-cancer agents are provided herein. | 12-31-2015 |
Patent application number | Description | Published |
20080230548 | CAN LID CLOSURE - A preferred embodiment of the disclosed can lid has a center panel having a central axis that is perpendicular to a diameter of the outer rim, or peripheral curl portion, of the can lid, an annular countersink surrounding the center panel, an arcuate portion extending radially outward from the annular countersink, a step portion extending radially upward and outward from the arcuate portion, a first transitional portion extending radially outward from the step portion, a second transitional portion extending radially outward and upward from the first transitional portion, and a peripheral curl portion extending outwardly from the second transitional portion. | 09-25-2008 |
20130264343 | DOUBLE OPENING BEVERAGE CAN LID SYSTEM - The embodiments disclosed describe a double opening beverage can lid system. The system includes a can lid having a pour panel associated with a pour opening and a vent panel associated with a vent opening. A tab is attached to the can lid. The tab includes a primary tab portion configured to open the pour opening, and a secondary tab portion configured to open the vent opening. A rivet hole facilitates attachment of the primary tab portion and the secondary tab portion to the can lid. A shelf is bent about 180° around a rear edge of the primary tab portion. The shelf blocks at least a portion of the secondary tab portion from contacting the vent panel. | 10-10-2013 |
20130264344 | DOUBLE-OPENING CAN LID - An improved beverage container of the type having a lid, a pour panel defined in the lid by a pour score and a vent panel defined in the lid by a vent score. A tab pivotally is mounted to the lid, wherein lifting the tab about a pivot in a lifting direction fractures the pour score and opens the pour panel. A secondary tab is carried by the tab, and is released into contact with the vent panel by lifting the tab to fracture the pour score, wherein pressing the tab in a direction generally opposite the lifting direction causes the secondary tab to fracture the vent score and open the vent panel. At least one anti-rotation member is disposed between the tab and the lid to prevent the tab from rotating about the rivet. | 10-10-2013 |
Patent application number | Description | Published |
20120203352 | MINIMALLY INVASIVE TOTAL HIP REPLACEMENT - A femoral implant for total hip replacement includes a cage screw, a femoral head and a base plate provided between the cage screw and the femoral head, to minimize the stress transferred from the femoral head to the bone. The femoral implant may optionally include devices for lateral fixation (for example, internal and/or external screws for lateral fixation) and a device for minimizing micro-motion that is integral to, and extends from, the cage screw. | 08-09-2012 |
20140243439 | MODIFIED POROUS MATERIALS AND METHODS OF CREATING INTERCONNECTED POROSITY IN MATERIALS - Techniques, mixtures and improved porous materials (interconnected porous constructs) that are capable of maintaining a sufficient porosity while conferring improved mechanical and physical strength to the final construct. A sacrificial construct (for example, a sacrificial material such as polymethyl methacrylate (PMMA)) is used to obtain an inverse porosity of the construct it was molded into. The process provides a less porous end material that may be used as an arthroplasty device or surgical implant (for example, an interference screw of suture anchor) among many other applications. The process employs a sacrificial material to reduce the porosity of the final construct to about 35%. | 08-28-2014 |
20150045797 | MENISCAL PROBE CUTTER - Instruments and methods that allow for a minimally invasive way to probe, locate, and cut a meniscus during a meniscectomy procedure. The instrument is a single hybrid probe/cutter instrument provided with both probing and cutting means that allow probing and cutting of the meniscus with the same hybrid instrument. A minimally invasive technique for probing and cutting (resecting) a torn area of a meniscus by employing the single, hybrid probing/cutting instrument is also provided. The technique provides a consistently good-quality meniscus with improved cosmetic results, and is simple and easily reproducible, strong, and time-saving for meniscal repairs. | 02-12-2015 |
Patent application number | Description | Published |
20140245727 | TURBINE ENGINE STARTING SYSTEM - System and method for starting a turbine engine are disclosed. These systems and methods for starting a turbine engine may be located on a vehicle, such as such as a Class 8 vehicle, equipped with a turbine engine as the prime mover or as a generator in a hybrid powertrain. In that regard, a fluid forcing device may be employed to start the turbine engine, such as an electric pump/compressor. The fluid forcing device may already be located on the vehicle for other purposes, and can include an electrically powered steering pump (also referred to as an electric pump) or an electrically powered air brake compressor (also referred to as an electric compressor). In order to start the turbine engine, the output of the electric pump/compressor drives an associated fluid circuit, which in turn, supplies fluid over a portion of the turbine shaft, wheel or scroll in order to impart rotational motion thereto. The rotational motion imparted to the turbine shaft, wheel or scroll aims to start the turbine engine. Once started, the output of the electric pump/compressor is either inhibited or redirected to power other devices, such as one or more vehicle accessories (e.g., steering gear, air brakes, power take off (PTO), air conditioner, etc). | 09-04-2014 |
20140248992 | ENGINE ACCESSORY DRIVE SYSTEM - An electrified engine accessory drive (EEAD) system is provided that replaces the front engine accessory drive (FEAD) components (e.g., a/c compressor, air brake compressor; power steering pump, etc.) on vehicles, such as heavy duty trucks. Using such an EEAD system aims to reduce parasitic losses induced on a conventional engine by the front engine accessory drive (FEAD) while providing additional benefits, such as engine off vehicle and/or system operation. The EEAD systems may also be used in lieu of rear-end accessory drives and other accessory drives powering multiple accessories from a common driveshaft. | 09-04-2014 |