Patent application number | Description | Published |
20080214598 | Novel Piperidine Carboxylic Acid Amide Derivatives - The invention relates to novel piperidine carboxylic acid amide derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of these novel compounds, pharmaceutical compositions comprising such compounds and especially the use of such compounds as inhibitors of renin. | 09-04-2008 |
20080234272 | Novel Piperazines as Antimalarial Agents - The invention relates to novel piperazine derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including pharmaceutical compositions containing one or more of those compounds and their use as medicaments for the treatment or prevention of protozoal infections, especially malaria. | 09-25-2008 |
20090099228 | PYRAZOLO-TETRAHYDRO PYRIDINE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS - The invention relates to novel pyrazolo-tetrahydropyridines compounds and their use as orexin receptor antagonists. | 04-16-2009 |
20090275588 | NOVEL SULFONAMIDE COMPOUNDS - The invention relates to novel sulfonamide compounds and their use as orexin receptor antagonists. | 11-05-2009 |
20090306123 | Bicyclononene derivaties - The invention relates to novel bicyclononene derivatives of Formula (I); and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin. | 12-10-2009 |
20100016401 | 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES - The invention relates to 3-aza-bicyclo[3.1.0]hexane derivatives of formula (I) wherein A, B, n, X, and R | 01-21-2010 |
20100029617 | 1,4,5,6,7,8-HEXAHYDRO-1,2,5-TRIAZA-AZULENE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS - The invention relates to 1,4,5,6,7,8-hexahydro-1,2,5-triaza-azulene derivatives and their use as orexin receptor antagonists. | 02-04-2010 |
20100069418 | 3-HETEROARYL (AMINO OR AMIDO)-1-(BIPHENYL OR PHENYLTHIAZOLYL) CARBONYLPIPERIDINE DERIVATIVES AS OREXIN RECEPTOR INHIBITORS - The invention relates to piperidine compounds of formula (I) wherein X-R | 03-18-2010 |
20100093740 | 5,6,7,8-TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE DERIVATIVES - The invention relates to 5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine derivatives of formula (I), wherein X represents CH | 04-15-2010 |
20100184808 | 3-AZA-BICYCLO[3.3.0]OCTANE COMPOUNDS - The invention relates to 3-aza-bicyclo[3.3.0]octane derivatives of the formula (I) wherein R | 07-22-2010 |
20100197733 | PYRROLIDINES AND PIPERIDINES AS OREXIN RECEPTOR ANTAGONISTS - The invention relates to compounds of formula (I) wherein Y, A, N and R | 08-05-2010 |
20100204285 | TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES - The invention relates to novel trans-3-aza-bicyclo[3.1.0]hexane derivatives of formula (I), wherein A, B, n and R | 08-12-2010 |
20100222328 | 2-CYCLOPROPYL-THIAZOLE DERIVATIVES - The invention relates to selected 2-cyclopropyl-thiazole derivatives of the formula (I) wherein B, Y and R1 are as described in the description; to salts and especially pharmaceutically acceptable salts thereof, and to the use of such compounds use as medicaments, especially as orexin receptor antagonists. | 09-02-2010 |
20100222600 | AZETIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS - The invention relates to novel azetidine compounds of formula (I), wherein R | 09-02-2010 |
20100324052 | NOVEL PIPERIDINE CARBOXYLIC ACID AMINE DERIVATIVES - The invention relates to novel piperidine carboxylic acid amide derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of these novel compounds, pharmaceutical compositions comprising such compounds and especially the use of such compounds as inhibitors of renin. | 12-23-2010 |
20110009401 | 2-AZA-BICYCLO[2.2.1]HEPTANE DERIVATIVES - The invention relates to novel 2-aza-bicyclo[2.2.1]heptane derivatives of formula (I), | 01-13-2011 |
20110009461 | 2-AZA-BICYCLO[3.3.0]OCTANE DERIVATIVES - The invention relates to 2-aza-bicyclo[3.3.0]octane derivatives of Formula (I) wherein A, B, and R | 01-13-2011 |
20110039857 | PIPERIDINE AND PYROOLIDINE COMPOUNDS - The invention relates to piperidine and pyrrolidine compounds of formula (I) | 02-17-2011 |
20110086889 | TETRAZOLE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS - The invention relates to tetrazole compounds of formula (I) wherein X, Y, Z, R | 04-14-2011 |
20110105491 | THIAZOLIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS - The invention relates to thiazolidine derivatives of the formula (I) wherein A, B, and R | 05-05-2011 |
20110105514 | 5,6,7,8-TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE COMPOUNDS - The invention relates to 5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine derivatives of formula (I) wherein R | 05-05-2011 |
20110124636 | 2-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS - The invention relates to novel 2-aza-bicyclo[3.1.0]hexane derivatives of Formula (I) wherein A, B, n and R | 05-26-2011 |
20110212968 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES - The invention relates to novel phenethylamide derivatives and their wherein A, B, R | 09-01-2011 |
20110263662 | 1,2-DIAMIDO-ETHYLENE DERIVATIVES AS OREXIN ANTAGONISTS - The invention relates to 1,2-diamido-ethylene derivatives of the formula (I) wherein R | 10-27-2011 |
20110281869 | TETRAHYDROISOQUINOLINES AS ANTIMALARIAL AGENTS - The invention relates to novel tetrahydroisoquinoline derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including pharmaceutical compositions containing one or more of those compounds and their use as medicaments for the treatment or prevention of protozoal infections, such as especially malaria. | 11-17-2011 |
20120088759 | THIAZOLIDIN-4-ONE AND [1,3]-THIAZINAN-4-ONE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS - The present invention relates to thiazolidin-4-one and [1,3]-thiazinan-4-one compounds of formula (I) wherein X, Y, R | 04-12-2012 |
20120101111 | NOVEL OXAZOLIDINONE DERIVIATIVES - The present invention relates to oxazolidinone derivatives of formula (I) wherein Y, R | 04-26-2012 |
20120142716 | 4-PYRIMIDINESULFAMIDE DERIVATIVE - The invention relates to the compound of structural formula (I) and the salts thereof. Said compound is useful as endothelin receptor antagonist. The invention further relates to a process for preparing said compound. | 06-07-2012 |
20120316178 | PIPERAZINES AS ANTIMALARIAL AGENTS - The invention relates to novel piperazine derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including pharmaceutical compositions containing one or more of those compounds and their use as medicaments for the treatment or prevention of protozoal infections, such as especially malaria. | 12-13-2012 |
20130109685 | 1-PHENYL-SUBSTITUTED HETEROCYCLYL DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS | 05-02-2013 |
20130150424 | PROLINE SULFONAMIDE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS - The present invention relates to (S)-proline sulfonamide compounds of formula (I) | 06-13-2013 |
20130237525 | LACTAM DERIVATIVES USEFUL AS OREXIN RECEPTOR ANTAGONISTS - The present invention relates to lactam derivatives of formula (I) | 09-12-2013 |
20130324579 | NOVEL PYRAZOLE AND IMIDAZOLE DERIVATIVES USEFUL AS OREXIN ANTAGONISTS - The present invention relates to pyrazole and imidazole derivatives of formula (I) wherein U, V, L, X, Y, R | 12-05-2013 |
20140045870 | 7-(Heteroaryl-Amino)-6,7,8,9-Tetrahydropyrido[1,2-A]Indol Acetic Acid Derivatives and Their Use as Prostaglandin D2 Receptor Modulators - The present invention relates to 7-(heteroaryl-amino)-6,7,8,9-tetrahydropyrido[1,2-a]indol acetic acid derivatives of the formula (I), | 02-13-2014 |
20150057328 | PROLINE SULFONAMIDE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS - The present invention relates to (S)-proline sulfonamide compounds of formula (I) | 02-26-2015 |