Patent application number | Description | Published |
20080241112 | Therapy of Kidney Diseases and Multiorgan Failure with Mesenchymal Stem Cells and Mesenchymal Stem Cell Conditioned Media - Methods and a composition for the treatment of organ dysfunction, acute renal failure, multi-organ failure, early dysfunction of kidney transplant, graft rejection, chronic renal failure, wounds, and inflammatory disorders including media conditioned by mesenchymal stem cells are provided. Methods for modulation of growth factor and cytokine expression including administering a therapeutic amount of mesenchymal stem cells, endothelial cells derived from mesenchymal stem cells, or media conditioned by mesenchymal stem cells are also provided. | 10-02-2008 |
20100034866 | Fused stem cells useful for the treatment of diabetes and methods thereof - Methods disclosed include methods of treating T1DM, said method comprising delivering a therapeutic amount of β-MSC to a subject in need thereof. Further disclosed are fusion cells comprising and MSC and a second cell wherein the nuclei of the MSC and the second cell are not fused in the fusion cell. | 02-11-2010 |
20100247491 | Potentiation of Stem Cell Homing and Treatment of Organ Dysfunction or Organ Failure - The invention provides methods and compositions for the treatment of multi-organ failure or kidney dysfunction, such as acute renal failure, by mesenchymal stem cells and a CD26 inhibitor, where inhibition of CD26 increases homing of the mesenchymal stem cells to a target tissue. | 09-30-2010 |
20110117064 | ASSAY FOR THE PREDICTION OF THERAPEUTIC EFFECTIVENESS OF MESENCHYMAL STROMAL CELLS, AND METHODS OF USING SAME - The invention relates to assays for testing the therapeutic effectiveness of mesenchymal stromal cell (MSC) populations and methods of treating pathologies with passaged and/or frozen and thawed MSC populations. | 05-19-2011 |
20110123498 | MESENCHYMAL STROMAL CELL POPULATIONS AND METHODS OF USING SAME - The invention relates to mesenchymal stromal cells produced by culturing the cells in platelet lysate supplemented media and methods of using these cells to treat neurological and kidney associated disorders. | 05-26-2011 |
20110259350 | Methods of Using SDF-1 (CXCL12) as a Diagnostic and Mesenchymal Stem Cell (Multipotent Stromal Cell)-Specific Therapeutic Biomarker for the Treatment of Kidney Injury and Other Major Organs - This application describes the detection and diagnosis of kidney pathology including acute kidney injury by the detection of changes in the amounts of biomarkers in the urine of patients. These biomarkers include stromal derived factor (SDF-1 or CXCL12). | 10-27-2011 |
20120148551 | MARROW STEM CELL AND PANCREATIC BETA CELL FUSION CELL USEFUL FOR THE TREATMENT OF DIABETES - Methods described include methods of treating T1DM, the method comprising delivering a therapeutic amount of β-MSC to a subject in need thereof. Further disclosed are fusion cells comprising and MSC and a second cell wherein the nuclei of the MSC and the second cell are not fused in the fusion cell. | 06-14-2012 |
20120269779 | MESENCHYMAL STROMAL CELL POPULATIONS AND METHODS OF USING SAME - The invention relates to mesenchymal stromal cells produced by culturing the cells in platelet lysate supplemented media and methods of using these cells to treat neurological and kidney associated disorders. | 10-25-2012 |
20120276067 | Assay for the Prediction of Therapeutic Effectiveness of Mesenchymal Stromal Cells, and Methods of Using Same - The invention relates to assays for testing the therapeutic effectiveness of mesenchymal stromal cell (MSC) populations and methods of treating pathologies with passaged and/or frozen and thawed MSC populations. | 11-01-2012 |
20140086886 | Stem Cell, Precursor Cell, or Target Cell-Based Treatment of Multi-Organ Failure and Renal Dysfunction - Methods for the treatment of acute renal failure, multi-organ failure, early dysfunction of kidney transplant, chronic renal failure, organ dysfunction, and wound healing are provided. The methods include delivering a therapeutic amount of hematopoietic stem cells, non-hematopoietic, mesenchymal stem cells, hemangioblasts, and pre-differentiated cells to a patient in need thereof. | 03-27-2014 |
20140120065 | PROTECTION FROM LETHAL IRRADIATION WITH MESENCHYMAL STROMAL CELLS - The present invention relates to the use of mesenchymal stromal cells (MSCs) for the treatment of supralethal radiation injury. | 05-01-2014 |
20140335058 | ASSAY FOR THE PREDICTION OF THERAPEUTIC EFFECTIVENESS OF MESENCHYMAL STROMAL CELLS, AND METHODS OF USING SAME - The invention relates to assays for testing the therapeutic effectiveness of mesenchymal stromal cell (MSC) populations and methods of treating pathologies with passaged and/or frozen and thawed MSC populations. | 11-13-2014 |