Christel
Christel Aebischer-Gumy, La Chaux-De-Fonds CH
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20130344604 | Expression Cassette - The present invention relates to an expression cassette useful for the expression of a polynucleotide sequence encoding a polypeptide. | 12-26-2013 |
20150056655 | EXPRESSION CONSTRUCTS AND METHODS FOR EXPRESSING POLYPEPTIDES IN EUKARYOTIC CELLS - The invention relates to an expression construct for the expression of polypeptides in host cells using alternative splicing. The expression construct can be used for the expression of polypeptides such as antibodies, antibody fragments and bispecific antibodies by expressing the gene products required for protein expression at the ratio leading to the highest titres or the best product quality profile. | 02-26-2015 |
Christel Beaumer, Carentan FR
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20120183484 | CARRAGEENAN MIXTURES USEFUL AS COSMETIC INGREDIENTS AND HAIR STYLING GELS COMPRISING THEM - This invention provides a carrageenan mixture comprising about 60% to about 95% by weight of iota-carrageenans and about 5% to about 25% by weight of lambda-carrageenans, which is useful as an ingredient of a cosmetic formulation such as a fully natural hair styling gel being free from synthetic polymers. | 07-19-2012 |
Christel Bernsdorf US
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20150299201 | BET PROTEIN-INHIBITING 5-ARYL TRIAZOLE AZEPINES - The present invention relates to BET-protein-inhibitory, in particular BRD4-inhibitory 5-aryltriazoloazepines of the general formula (I) | 10-22-2015 |
Christel Bonnas, Gauting DE
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20110300114 | METHOD OF CELL CULTURE AND METHOD OF TREATMENT COMPRISING A vEPO PROTEIN VARIANT - In one aspect the present invention is concerned with a method of cell culture, comprising the steps of (i) obtaining a stem or progenitor cell sample, (ii) culturing the stem or progenitor cell sample in media and under closed conditions appropriate to cause proliferation or differentiation of the stem or progenitor cells, wherein the media comprises a vEPO protein variant, (iii) purifying the stem or progenitor cells ex vivo. The invention relates to a method of increasing the number and survival of stem and progenitor cells in vitro and in vivo using a vEPO protein variant. The invention also relates to improved differentiation of stem and progenitor cells in vitro and in vivo using a vEPO protein variant. | 12-08-2011 |
Christel Bonnas, Gauling DE
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20110008363 | ERYTHROPOIETIN VARIANTS - The present invention relates to novel endogenous variants of erythropoietin (EPO) and their use for treatment or prevention of a condition associated with tissue damage due to cell death (apoptosis, necrosis) and inflammation, in particular for neuroprotection, e.g. treatment of acute (for example stroke) and chronic disease (for example ALS) of the nervous system. | 01-13-2011 |
Christel Carrigues, Frederiksberg C DK
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20150320099 | COMPOSITIONS AND METHODS FOR REDUCED CARBOHYDRATES AND INCREASED ERYTHRITOL IN BEVERAGES - The present invention provides novel compositions and methods for naturally decreasing carbohydrates and calories, while increasing erythritol, in beverages. The method includes fermenting beverages, such as fruit juices with a microorganism capable of metabolizing sugars into sugar alcohol(s) such as erythritol, to produce a fermented beverage having reduced carbohydrates, and therefore reduced calories, and increased erythritol as compared to an unfermented equivalent beverage. | 11-12-2015 |
Christel Chamaret, Chantepie FR
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20090324088 | Method for detecting layout areas in a video image and method for generating an image of reduced size using the detection method - The invention relates to an automatic detection method in a source image, of at least one area called a layout area comprising at least one layout, such as a logo and/or a score. According to the invention, the layout areas of a source image are detected using the salience of source image pixels. The detection is carried out in specific areas of the source image saliency map, usually in the areas corresponding to the comers of the image or to the bands in the upper part and lower part of the image. In these areas, two points are sought having maximum salience values and distant by at least p points from each other. These two points corresponding to the beginning and end of a layout area. The window bounding these two points then corresponds to a layout area. | 12-31-2009 |
20100188430 | Method for image format conversion with insertion of an information banner - The present invention relates to a method for image processing to generate, from a source image having a predefined width to height ratio, called initial ratio, and an information banner having predefined width to height ratio, called banner ratio, a final image having a width called final and a height called final and for which the width to height ratio, called final ratio, is different from said initial ratio, comprising the following steps: | 07-29-2010 |
20120150849 | METHOD FOR SELECTING VERSIONS OF A DOCUMENT FROM A PLURALITY OF VERSIONS RECEIVED AFTER A SEARCH, AND RELATED RECEIVER - The present invention pertains to a method for selecting a version of a document. The user inputs an identifier of a document at the level of his receiver connected to at least one communication network, and initiates a search request to receive versions of at least one part of this document. The receiver then receives a plurality of versions of the said document. Each version received is analysed by a plurality of evaluation modules so as to calculate an evaluation value for each version received according to a predetermined criterion. The receiver selects for each of the evaluation modules a version of the document having the best evaluation in respect of this criterion, and displays the identifiers of versions having the best evaluations according to each criterion. The user can then easily select the version for reproduction thereof which best meets a criterion. The invention also relates to a receiver implementing the said method. | 06-14-2012 |
20130028511 | Method and device of determining a saliency map for an image - The invention proposes a method and a device of determining a saliency map for an image. | 01-31-2013 |
20140002742 | METHOD FOR REFRAMING IMAGES OF A VIDEO SEQUENCE, AND APPARATUS FOR REFRAMING IMAGES OF A VIDEO SEQUENCE | 01-02-2014 |
20140204176 | METHOD FOR REDUCING THE SIZE OF A STEREOSCOPIC IMAGE - In an image processing method to display a stereoscopic image on a target screen, a disparity information ( | 07-24-2014 |
20140232821 | METHOD AND DEVICE FOR RETARGETING A 3D CONTENT - A method of cropping a 3D content comprising at least a first view and a second view is disclosed that comprises: | 08-21-2014 |
20140348421 | METHOD AND DEVICE FOR PROCESSING A PICTURE - A method for processing a picture is disclosed. The method according to the invention comprises: | 11-27-2014 |
20140380355 | METHOD AND APPARATUS FOR INSERTING A VIRTUAL OBJECT IN A VIDEO - A method and an apparatus for inserting a virtual object in a video are described. The method utilizes a saliency map that characterizes the gaze allocation from a viewer on an image of the video and inserts the virtual object in the image of the video based on the saliency map. The method comprises: generating a saliency map of the image of the video after the insertion of the virtual object; and adjusting the insertion of the virtual object based on the saliency map by adjusting at least one visual characteristic of the inserted virtual object. | 12-25-2014 |
20150077639 | COLOR VIDEO PROCESSING SYSTEM AND METHOD, AND CORRESPONDING COMPUTER PROGRAM - A color video processing method is disclosed that comprises: | 03-19-2015 |
20150092983 | METHOD FOR CALIBRATION FREE GAZE TRACKING USING LOW COST CAMERA - A method and device for eye gaze estimation with regard to a sequence of images. The method comprises receiving a sequence of first video images and a corresponding sequence of first eye images of a user watching at the first video images; determining first saliency maps associated with at least a part of the first video images; estimating associated first gaze points from the first saliency maps associated with the video images associated with the first eye images; storing of pairs of first eye images/first gaze points in a database; for a new eye image, called second eye image, estimating an associated second gaze point from the estimated first gaze points and from a second saliency map associated with a second video image associated with the second eye image; storing the second eye image and its associated second gaze point in the database. | 04-02-2015 |
20150178587 | DEVICE AND A METHOD FOR COLOR HARMONIZATION OF AN IMAGE - A method for processing an image is disclosed. The method comprises: | 06-25-2015 |
20150179220 | APPARATUS AND METHOD OF PROCESSING MULTIMEDIA CONTENT - The invention discloses an apparatus and a method of processing a multimedia content. A content processing apparatus includes: a display displaying a multimedia content and associated levels of at least one characteristic of at least two components of the multimedia content; an interface receiving a command for modifying the level of the at least one characteristic of at least one of the components with regard to at least one of the other components; and a processor modifying the at least one of the at least two components according to the level of the at least one characteristic requested by the command. | 06-25-2015 |
20150332605 | METHOD FOR HARMONIZING COLORS, CORRESPONDING COMPUTER PROGRAM AND DEVICE - A method for harmonizing colors of an original image is disclosed. The method comprises: | 11-19-2015 |
Christel Chamaret, Cesson Sevigne FR
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20130094587 | METHOD AND DEVICE FOR DETERMINING A SALIENCY VALUE OF A BLOCK OF A VIDEO FRAME BLOCKWISE PREDICTIVE ENCODED IN A DATA STREAM - The invention is made in the field of saliency determination for videos block-wise predictive encoded in a data stream. | 04-18-2013 |
20140153651 | METHOD AND APPARATUS FOR REFRAMING AND ENCODING A VIDEO SIGNAL - Reframing is used to re-size an image or video content, e.g. for displaying video signals with a given aspect ratio on a display having a different aspect ratio. Window cropping parameters (position and size over time) are constrained in order to optimise the rate/distortion of the encoded output video signal. Initial reframing is improved by computing a saliency map representing a user attention map which considers the video coding context and by providing a macroblock coding efficiency cost map and then taking the saliency map or a combined saliency/coding cost map into account so that the coding cost for said reframed video signal is smaller than the coding cost for other candidate reframing windows' sizes and positions. | 06-05-2014 |
Christel Charrat, La Turbie FR
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20150347408 | MANAGING RECORDS IN A TRAVEL MANAGEMENT SYSTEM - Methods, apparatus, and computer program products for managing an extended record data structure in a content management system. A plurality of records are stored in an extended record data structure that include first data containers containing standard data elements and second data containers containing non-standard data elements. A record identifier is assigned to each record in the extended data structure for which one or more of the standard data elements and one or more of the non-standard data elements are related. For each record, an entry is created in an auxiliary data structure. The entry shares the record identifier of the record and comprises an auxiliary data container. The auxiliary data container includes a set of attributes related to the first and second data containers sharing the same record identifier in the record data structure. The extended record data structure is managed based on the auxiliary data structures. | 12-03-2015 |
20150347476 | CONTENT MANAGEMENT IN A TRAVEL MANAGEMENT SYSTEM - Methods, apparatus, and computer program products for managing content in a travel management system. A standard data element and a non-standard data element comprising the content are received from one or more content providers. A first data container for the standard data element and a second data container for the non-standard data element are created in an extended record data structure. The first data container includes a common record identifier and first data values for first attributes corresponding to the standard data element. The second data container includes the common record identifier and second data values corresponding to second attributes for the non-standard data element. The travel management system manages access to the first container and the second container in the extended record data structure based on the common record identifier. | 12-03-2015 |
20150347589 | CONTENT ACCESS IN A TRAVEL MANAGEMENT SYSTEM - Methods, systems, and computer program products for accessing content in a travel management system. A request is received from an application to access a standard data element and a non-standard data element from an extended record data structure based at least in part upon access criteria. A plurality of attributes of a data container associated with the non-standard data element are filtered based at least in part upon a plurality of predefined filtering rules in order to generate filtered attributes. An abstract container is generated that includes the filtered attributes of the non-standard data element and that is assigned a unique abstract type. | 12-03-2015 |
20150347929 | CONTENT EXCHANGE WITH A TRAVEL MANAGEMENT SYSTEM - Methods, apparatus, and computer program products for exchanging content with a content management system comprising an extended record data structure. A plurality of records are maintained at the travel management system in an extended record data structure that includes first data containers containing standard data elements and second data containers containing non-standard data elements. Each non-standard data element is associated with a respective structure description file defining a structure of the attributes of the non-standard data element. A first data exchange message is generated at the travel management system and includes the structure description file of one of the non-standard data elements and a set of values corresponding to values of the attributes of the one of the non-standard data elements. The first data exchange message is transmitted according to a first data exchange format from the travel management system to the client device. | 12-03-2015 |
Christel Charrat, Vallarius FR
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20120259667 | RESERVATION METHOD AND SYSTEM WITH IMPROVED PNR HANDLING - The method and system according to a preferred embodiment of the present invention allows storing and proposing a list of saved quotes, referred to as “Offers”, together with the PNR. These Offers once created can be communicated to the passenger, so he could access them and make his choice in a cross-channel, interactive dialog with the proposing agent. Standard PNR have been enhanced to accommodate quotations/offers on top of firm bookings. As well as making the search efforts of the user persistent and re-usable, the inclusion of quotation in the PNR makes them accessible via all the distribution channels and gives to this invention a full cross-channel dimension. This new functionality represents as well a huge enhancement in the Travel Agent work flow, since the saving of all the pre-booking activity is now automated and traceable, by the agent himself (for follow-up and confirmation purpose) and eligible for sending to commonly used Mid-Office and reporting systems. | 10-11-2012 |
20130346123 | RESERVATION METHOD AND SYSTEM WITH IMPROVED PNR HANDLING - A method and system for storing and proposing a list of saved quotes, referred to as “Offers”, together with the PNR. These Offers once created can be communicated to the passenger, so he could access them and make his choice in a cross-channel, interactive dialog with the proposing agent. Standard PNR have been enhanced to accommodate quotations/offers on top of firm bookings. As well as making the search efforts of the user persistent and re-usable, the inclusion of quotation in the PNR makes them accessible via all the distribution channels and gives to this invention a full cross-channel dimension. This new functionality represents as well a huge enhancement in the Travel Agent work flow, since the saving of all the pre-booking activity is now automated and traceable, by the agent himself (for follow-up and confirmation purpose) and eligible for sending to commonly used Mid-Office and reporting systems. | 12-26-2013 |
Christel Dieppedale, Crolles FR
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20120021550 | METHOD FOR FABRICATING A FIXED STRUCTURE DEFINING A VOLUME RECEIVING A MOVABLE ELEMENT IN PARTICULAR OF A MEMS - The fabrication of a semiconductor fixed structure defining a volume, for example of a MEMS micro electro-mechanical system includes, determining thicknesses beforehand depending on the functional distances associated with elements. At least one element is formed on a substrate by thermal oxidation of the substrate so as to form an oxide layer followed by selective etching of the oxide layer so as to define the volume in an etched portion by baring the underlying substrate so as to define the element in an unetched portion, and later oxidation of the substrate so as to form an oxide layer, in order to obtain the elements at the functional distances. | 01-26-2012 |
Christel Dumez, Savigny Sur Orge FR
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20140334594 | NUCLEAR REACTOR PRIMARY CIRCUIT, WITH A BRANCH EQUIPPED WITH A THERMAL SLEEVE - A nuclear reactor primary circuit with a branch equipped with a thermal sleeve is provided. The nuclear reactor primary circuit includes a primary tubing, having an inner surface delimiting an inner volume in which a primary fluid circulates for cooling the nuclear reactor; a branch fastened to the primary tubing and delimiting an inner passage communicating with the inner volume of the primary tubing; a sleeve, having a first end connected to the branch and a second free end engaged in the inner volume of the primary tubing, the second end protruding in the inner volume relative to the inner surface over a non-zero length, an annular space being delimited between the sleeve and the branch. The primary circuit comprises a device making the sleeve unlosable, the unlosability device comprising at least one first raised portion formed on the branch, at least one second raised portion formed on the sleeve and capable of cooperating with the first raised portion to prevent the sleeve from falling into the primary tubing if the sleeve separates from the branch. | 11-13-2014 |
Christel Fenge, Sodertalje SE
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20110092429 | COMPOSITIONS AND METHODS FOR PRODUCING GAMMA-CARBOXYLATED PROTEINS - The present invention relates to methods and tools for producing large quantities of gamma-carboxylated protein comprising: (i) culturing a cell adapted to express a protein which requires gamma-carboxylation and γ-glutamyl carboxylase in a ratio of at least 10:1, under conditions suitable for expression of both proteins, and (ii) isolating gamma-carboxylated protein. | 04-21-2011 |
Christel Fiorini-Puybaret, L'Union FR
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20110256087 | COSMETIC COMPOSITION CONTAINING A LOCUST BEAN GUM HYDROLYSATE - The invention relates to a locust bean gum hydrolysate, to a method for preparing same, and to the use thereof in hair cosmetics. | 10-20-2011 |
Christel Fiorini-Puybaret, Toulouse FR
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20090324754 | EUCALYPTUS EXTRACT, METHOD OF PREPARATION AND THERAPEUTIC USES THEREOF - The present invention relates to the use of a | 12-31-2009 |
20100286284 | 5-[1'-(DECAHYDRO-7-HYDROXY-1,1,3A,7-TETRAMETHYL-1H-CYCLOPROPA[A]NAPHTHALEN- -4-YL)-3'-METHYLBUTYL]-2,4,6-TRIHYDROXY-1,3-BENZENEDICARBOXALDEHYDE AS MEDICAMENTS - The present invention relates to new compounds of formula (I) and to their use as medicaments. Preferably, the said compounds are used in the preparation of a medicament or food supplement intended for the treatment and/or prevention of ailments or pathologies ensuing from a disorder of the reuptake of the following neurotransmitters: dopamine, serotonin and/or noradrenaline. | 11-11-2010 |
20110268686 | COSMETIC COMPOSITION INCLUDING AN ACANTHUS EXTRACT, AND USE OF ACANTHUS IN A COSMETIC HAIR-CARE COMPOSITION - The present invention relates to a new advantageous utilisation of acanthus in the cosmetic field, and more especially in a haircare composition for creating and/or maintaining the curling effect. | 11-03-2011 |
20150023902 | COSMETIC USE OF AN EXTRACT OF BALANITES ALMONDS TO IMPROVE HAIR STRENGTH - The invention concerns the use of a cosmetic compound to improve hair strength, said cosmetic compound comprising as an active ingredient an extract of Balanites almonds. | 01-22-2015 |
20150190447 | USE OF A MYRTLE EXTRACT AS AN ANTI-BIOFILM AGENT AGAINST P. ACNES - The invention relates to a dermatological composition containing a myrtle extract in a concentration that is higher than or equal to 0.01 wt.%, for the use thereof as an anti-biofilm agent against | 07-09-2015 |
Christel Fussangel, Neuss DE
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20120177934 | METHOD FOR THE PRODUCTION OF STRETCHABLE ELECTRODES - The invention relates to a method for producing stretchable electrodes, where electrically conductive carbon particles, especially carbon nanotubes, are introduced into a coating comprising an elastomer. In said method, a preparation of non-aggregated carbon particles having an average particle diameter ranging from=0.3 nm to=3000 nm in a solvent acts upon a coating comprising an elastomer. The solvent can cause a coating comprising an elastomer to swell. The duration of the action is calculated so as to be insufficient to dissolve the elastomer. Optionally, another electrically conductive layer is applied. The invention also relates to a stretchable electrode obtained in said manner and to the use thereof. | 07-12-2012 |
Christel Garrigues, Frederiksberg C DK
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20120021093 | METHOD FOR PRODUCING AN ACIDIFIED MILK PRODUCT - The present invention relates to a method for producing an acidified milk product using an enzyme having transglutammase activity. | 01-26-2012 |
20130142765 | LACTOCOCCUS LACTIS STRAIN WITH HIGH VITAMIN K2 PRODUCTION - The present invention relates to a novel wild-type | 06-06-2013 |
20130142896 | LACTOCOCCUS LACTIS STRAIN WITH HIGH VITAMIN K2 PRODUCTION - The present invention relates to a novel wild-type | 06-06-2013 |
20140120577 | Metalloporphyrin Inducible Promoter - The invention relates to a promoter inducible by metalloporphyrins. Said promoter is useful for controlling the expression of genes of interest in gram-positive bacteria deficient in heme biosynthesis, in particular lactic acid bacteria. | 05-01-2014 |
20150030722 | METHOD FOR PRODUCING AN ACIDIFIED MILK PRODUCT - The present invention relates to a method for producing an acidified milk product using an enzyme having transglutaminase activity. | 01-29-2015 |
Christel Geukens, Mortsel BE
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20100040976 | HEAT-SENSITIVE IMAGING ELEMENT - A heat-sensitive imaging element includes an IR dye, and more particularly a heat-sensitive lithographic printing plate precursor includes the IR dye. A method for making the lithographic printing plate produces a print-out image of high contrast upon exposure to IR-radiation or heating. | 02-18-2010 |
20100209851 | METHOD OF MAKING A LITHOGRAPHIC PRINTING PLATE - A method of making a lithographic printing plate comprising the steps of: a) providing a lithographic printing plate precursor comprising a support having a hydrophilic surface or which is provided with a hydrophilic layer, and a coating provided thereon, said coating comprising (i) a contiguous photopolymerisable layer having a photopolymerisable composition, or (ii) a contiguous intermediate layer and thereon a photopolymerisable layer having a photopolymerisable composition, wherein said photopolymerisable composition comprises a polymerisable compound, a polymerization initiator and a first polymer, b) image-wise exposing said coating, c) optionally, heating the precursor, d) developing the precursor by treating the coating of the precursor with a gum solution or by mounting the exposed precursor on a plate cylinder of a lithographic printing press and rotating the plate cylinder while feeding dampening liquid and/or ink to the coating, wherein said contiguous photopolymerisable or intermediate layer further comprises (1) an adhesion promoting compound which is a non-polymeric compound containing a group having an ethylenically unsaturated bond and a group selected from a phosphate group, a phosphonate group and a trialkoxysilane group, and (2) a second polymer having at least 1 mol % of a first monomeric unit having a phosphate group, a phosphonate group, a carboxylic acid group, a sulphonic acid group, a phenolic group, a trialkoxysilane group, an ammonium group or a phosphonium group and at least 30 mol % of a second monomeric unit having a hydrophilic group, wherein the amount of said adhesion promoting compound is higher than the amount of said second polymer, with the proviso that, if the contiguous layer is the photopolymerisable layer, the amount of said second polymer xn the photopolymerisable layer is at least 0.01% by weight and less than 5% by weight. | 08-19-2010 |
20100221662 | HEAT-SENSITIVE IMAGING ELEMENT - A heat-sensitive imaging element includes an IR dye having a structure according to Formula I, | 09-02-2010 |
Christel Gigandet, Remaufens CH
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20120248143 | POWDER DISPENSING CANISTER - The invention concerns a dispensing canister comprising:—a reservoir ( | 10-04-2012 |
Christel Guibourdenche, Basel CH
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20140018376 | Use of 1H-Quinazoline-2,4-Diones - The invention concerns the use of competitive AMPA receptor antagonists for the treatment, prevention or delay of progression of Rasmussen's encephalitis and/or certain forms of epilepsy. | 01-16-2014 |
Christel Guibourdenche, Aesch Bl CH
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20100144747 | 1H-QUINAZ0LINE-2,4-DIONES - The present invention relates to 1H-Quinazoline-2,4-diones of formula (I) | 06-10-2010 |
20110294818 | 1H-QUINAZOLINE-2,4-DIONES - The present invention relates to 1H-Quinazoline-2,4-diones of formula (I) | 12-01-2011 |
20130296332 | 1H-QUINAZOLINE-2,4-DIONES - The present invention relates to 1H-Quinazoline-2,4-diones of formula (I) | 11-07-2013 |
Christel Herold-Mende, Bammental DE
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20100322922 | Neutralization of CD95 Activity Blocks Invasion of glioblastoma Cells In Vivo - The present invention relates to methods for treating an individual with high grade glioblastoma multiforme by preventing or disrupting the binding of CD95 to its ligand, CD95L, in vivo, whereupon that neutralization of CD95 activity reduces undesirable glial cell migration and invasion into body tissue. | 12-23-2010 |
20130209413 | USE OF PARVOVIRUS FOR ELIMINATING CANCER STEM CELLS (CSCs) - Described is the use of a parvovirus, preferably H-1PV, for the therapeutical elimination of cancer stem cells (CSCs), preferably neuroblastoma stem cells and glioblastoma stem cells. | 08-15-2013 |
Christel Hittinger, Mannheim DE
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20100113693 | Continuous method for producing highly methylolated melamine and etherified melamine formaldehyde resins - The invention relates to a process for preparing polymethylolated melamine and polymethylolated melamine compounds polyetherified with alkanol, wherein the methylolation reaction is carried out in a kneading reactor. | 05-06-2010 |
Christel Laberty-Robert, Alexandria, VA US
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20090155693 | DISPERSED SOLUTION OF CARBON-CONTAINING MATERIALS FOR THE PRODUCTION OF CURRENT COLLECTORS - A method of preparing a dispersed solution of carbon-containing particles of nanometric size includes: preparing a polymeric matrix of a determined viscosity, then introducing into the matrix a fraction of carbon-containing particles and a fraction of wetting agent, the solvent of the matrix, and maintaining under agitation until a sol of stable viscosity is obtained, these operations being repeated until the carbon-containing particles and the solvent are exhausted. The dispersal solution includes: in a ratio to the total volume of solution: i) 1% to 4%, preferably 2% to 4% (m/v), of carbon-containing particles in suspension, ii) 20% to 40% (v/v) of a polymeric matrix, and iii) a wetting agent, the solvent of the polymeric matrix, said dispersed solution comprising neither binder nor dispersing agent. | 06-18-2009 |
Christel Larbouret, Valflaunes FR
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20140141019 | ANTIBODIES AGAINST HER3 - The invention relates to antibodies against HER3 and their use in the treatment of cancer. | 05-22-2014 |
Christel Larbouret, Montpellier FR
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20090214541 | Combination Therapy Using Anti-EGFR and Anti-HER2 Antibodies - The invention relates to the combined use of anti-EGFR antibodies and anti-Her2 antibodies for the treatment of cancer, especially suitable for cancer expressing high levels of the EGFR type and low levels of HER2. The invention refers in particular monoclonal antibody “trastuzumab” (HERCEPTIN®) directed against the HER2 receptors the efficacy of which can be significantly increased in vivo when combined with monoclonal antibody “matuzumab” (hmAB 425, EMD 72000) directed against EGF receptors. The combination treatment is suitable for patients suffering from cancer having said receptor profile, preferably pancreatic cancer. | 08-27-2009 |
20140112931 | ANTI-HUMAN HER3 ANTIBODIES AND USES THEREOF - The present invention provides for isolated anti-human-HER3 antibodies or fragments thereof. More particularly the present invention provides an isolated monoclonal antibody that specifically binds to the extracellular domain of HER-3 and competes for binding to the extracellular domain of human HER-3 with the antibody produced obtainable from hybridoma deposited as CNCM-I-4486. The antibodies described in the present invention are useful for the treatment of cancer. | 04-24-2014 |
20150132308 | Combination Therapy Using Anti-EGFR And Anti-HER2 Antibodies - The invention relates to the combined use of anti-EGFR antibodies and anti-Her2 antibodies for the treatment of cancer, especially suitable for cancer expressing high levels of the EGFR type and low levels of HER2. The invention refers in particular monoclonal antibody “trastuzumab” (HERCEPTIN®) directed against the HER2 receptors the efficacy of which can be significantly increased in vivo when combined with monoclonal antibody “matuzumab” (hmAB 425, EMD 72000) directed against EGF receptors. The combination treatment is suitable for patients suffering from cancer having said receptor profile, preferably pancreatic cancer. | 05-14-2015 |
Christel Larbouret, Montpellier Cedex 5 FR
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20140302041 | ANTI-AXL ANTIBODIES AND USES THEREOF - The present invention relates to anti-Axl antibodies and uses thereof in diagnostic and therapeutic methods. More particularly, the present invention relates to a monoclonal antibody having specificity for Axl comprising an heavy chain variable region comprising SEQ ID NO:2 in the H-CDR1 region, SEQ ID NO:3 in the H-CDR2 region and SEQ ID NO:4 in the H-CDR3 region; and a light chain variable region comprising SEQ ID NO: 6 in the L-CDR1 region, SEQ ID NO:7 in the L-CDR2 region and SEQ ID NO:8 in the L-CDR3 region. Said monoclonal antibody binds to the extracellular domain of Axl via, SEQ ID NO:9, SEQ ID NO: 10 and SEQ ID NO: 11. | 10-09-2014 |
Christel Liviero, Paris FR
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20090105330 | ADMIXTURE OF CAROTENOIDS AND ISOFLAVONOIDS FOR TREATING CUTANEOUS SYMPTOMS OF AGING - Intimate admixtures of at least one carotenoid and at least one isoflavonoid are well suited for treating the undesirable cutaneous signs of skin aging, in particular the determination of the skin and/or of the mucous membranes by inhibiting the activity and/or the expression of collagenases and by increasing the synthesis of collagen. | 04-23-2009 |
Christel Mueller, Schulzendorf DE
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20080215519 | METHOD AND DATA PROCESSING SYSTEM FOR THE CONTROLLED QUERY OF STRUCTURED SAVED INFORMATION - A method for the controlled querying of information stored in a structured format in a data processing system using a dialog system includes: providing at least one first ontology configured to store information in a structured format; and providing at least one input grammar in the dialog system configured to analyze user inputs as a function of the at least one first ontology. | 09-04-2008 |
20100324909 | METHOD AND SYSTEM FOR PROCESSING MESSAGES WITHIN THE FRAMEWORK OF AN INTEGRATED MESSAGE SYSTEM - A method and system for processing messages within the framework of an integrated message system. Recipients of messages in an integrated messaging system are provided with an authentic impression of the received message. In a first step, a message received within the framework of an integrated messaging system is automatically translated. Language detection and dictation system is provided. The message contents of the incoming message as well as its segments and parameters are simultaneously utilized to generate additional information regarding the sender and the information, which is suitable to give the recipient an impression of the received message in the most authentic form possible. | 12-23-2010 |
Christel Mueller-Goymann, Braunschweig DE
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20100197791 | PHARMACEUTICALS FOR TRANSDERMAL USE ON ANIMALS - The invention relates to pharmaceutical preparations for use on animals, which are applied to the fur or the skin of the animal and whose active ingredient subsequently undergoes transdermal absorption. | 08-05-2010 |
Christel Muller-Goymann, Braunschweig DE
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20080227757 | Formulation for dermal application - The present invention relates to formulations on an aqueous basis with polyetherpolyol, dimethyl isosorbide, lipid and alcohol content suitable for penetration reinforcement of pharmaceutical active ingredients in the dermal application. The pharmaceutical active ingredients can be amphiphilic, zwitterionic, strongly polar or lipophilic. A preferred active ingredient is 5-aminolevulinic acid. | 09-18-2008 |
Christel Müller-Goymann, Braunschweig DE
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20120010227 | FORMULATION FOR NAIL AND NAIL BED DISEASES - The invention relates to a pharmaceutical composition with a content in active ingredient that can be an antimycotic, so that the composition is suitable for the treatment of onychomycoses, in particular severe onychomycoses. The inventive formulation is an ointment-like thermogel at body temperature and an inviscid thermogel at lower temperatures and facilitates the permeation of sufficient active ingredient quantities through human fingernails and toenails, in order to also treat severe onychomycoses. | 01-12-2012 |
Christel Noehringer, Colmar FR
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20090110595 | Decontamination method and system implementing it - The method of microbiological decontamination of a machine comprising an enclosure ( | 04-30-2009 |
20110206559 | Decontamination Method And System Implementing It - The method of microbiological decontamination of a machine comprising an enclosure ( | 08-25-2011 |
Christel Noemayr, Muenchen DE
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20110232733 | Multi-Junction Solar Cell For Space Applications - A multi-junction solar cell includes a first main surface and a second main surface opposite to the first main surface of a semiconductor body. A topmost pn-junction of a plurality of pn-junctions stacked on top of each other adjoins to the first main surface. A cell edge of the semiconductor body defines a shape of the first and the second main surfaces. An encapsulant on the first main surface provides an environmental protection of the semiconductor body. A mesa groove is provided on the first main surface and penetrates at least the topmost pn-junction. The mesa groove is located adjacent to the cell edge and is created around the circumference of the semiconductor body for providing an inner cell area and a mesa wall, the mesa wall being created between the mesa groove and the cell edge. The mesa groove is filled with the encapsulant. | 09-29-2011 |
Christel Paroth, Tuttlingen DE
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20120228355 | SURGICAL INSTRUMENT - A surgical instrument includes an implant, a grip, and a pre-set breaking point connecting the implant and the grip. The implant has a joining profile. | 09-13-2012 |
20130012954 | SURGICAL INSTRUMENT - A surgical instrument for seating a pedicle screw may comprise a driver head, a pressure ring, or at least one guide element. The driver head may be configured for removably connecting to the pressure ring or the at least one guide element, or a pressure ring and at least one guide element. The removable connection of the pressure ring or the at least one guide element from the driver head may be twistable or slidable for purposes of exchanging the pressure ring or the at least one guide element from the driver head. The pressure ring or at least one guide element is configured to operatively engage the pedicle screw and transfer motion of the surgical instrument to the pedicle screw. | 01-10-2013 |
20150088199 | SURGICAL INSTRUMENT - A surgical instrument includes an implant, which may include a cannulated pedicle screw having a screw head, a tulip connected to the screw head, an extension connected to the tulip, an ini threadedly engaged with at least one of the tulip and the extension, and/or a guide wire disposed in at least one of the extension, the tulip, and the implant. | 03-26-2015 |
20150094781 | SURGICAL INSTRUMENT - A surgical instrument for separating an introducer sheath from a device connected to the introducer sheath is disclosed. In embodiments, the surgical instrument includes an extension extending in a longitudinal direction; a pin; and a separator connecting the extension and the pin. | 04-02-2015 |
Christel Piscina, Nice FR
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20140379389 | TRAVEL BOOKING INVENTORY MANAGEMENT - Methods, systems, and computer program products for managing the booking of travel inventory items at an inventory system. A booking request for a type of travel inventory item managed by the inventory system may be received at the inventory system. An expiration time may be determined based at least in part on the booking request, and a travel booking for a travel inventory item of the type may be confirmed based at least in part on the booking request. The inventory system may be updated based on the booked travel inventory item. | 12-25-2014 |
Christel Prioleau, Rueil Malmaison FR
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20130062950 | DEVICE FOR SUPPLYING AUXILIARY POWER TO AN ITEM OF EQUIPMENT ON A CURRENT-LIMITED POWER SUPPLY BUS - The power supply circuit for powering equipment via a current-limited power supply bus at a nominal voltage (Vb) of the equipment includes an auxiliary power supply circuit comprising an energy storage member and a trigger member for triggering auxiliary power supply to the equipment from the storage member via a voltage-reducing converter for reducing the auxiliary voltage to the nominal voltage. | 03-14-2013 |
Christel Ravier, Tournefeuille FR
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20100045486 | METHOD AND DEVICE FOR AUDIBLE WARNING WHEN AN AIRCRAFT AUTOPILOT IS DEACTIVATED - The invention relates to a method for producing an audible warning when an aircraft autopilot ( | 02-25-2010 |
Christel Vollstedt, Tornesch DE
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20090221031 | NOVEL GROUP OF ESTERASES FOR THE PRODUCTION OF FINE AND SPECIALITY CHEMICALS - The present invention relates to a polynucleotide encoding an enzyme having carboxyl esterase [E.C. 3.1.1.1] activity, wherein the coding sequence is selected from the group consisting of (a) a polynucleotide encoding an amino acid sequence as depicted in any one of SEQ ID NOs: 2, 4, 6 and 8; (b) a polynucleotide having or comprising a nucleotide sequence encoding an enzyme, wherein the nucleic acid sequence is as shown in any one of SEQ ID NOs: 1, 3, 5 and 7; (c) a polynucleotide having or comprising a nucleotide sequence encoding a fragment or derivative of an enzyme encoded by a polynucleotide of (a) or (b), wherein in said derivative one or more amino acid residues are conservatively substituted compared to the amino acid sequence of (a); (d) a polynucleotide encoding an enzyme having carboxyl esterase activity which polynucleotide is at least 65% identical to a polynucleotide encoding an enzyme as shown in one of SEQ ID NOs: 2, 4, 6 and 8; (e) a polynucleotide having or comprising a nucleotide sequence the complementary strand of which hybridizes to a polynucleotide as defined in any one of (a) to (d); and (f) a polynucleotide having or comprising a nucleotide sequence being degenerate to the nucleotide sequence of the polynucleotide of (d) or (e); or the complementary strand of such a polynucleotide of (a) to (f) or fragments thereof useful as specific probes or primers. The present invention also relates to a host, genetically engineered with the polynucleotide of the present invention or the vector of the present invention. The present invention also relates to a polypeptide comprising the amino acid sequence encoded by a polynucleotide of the present invention or which is obtainable by the process of the present invention. Moreover, the present invention relates to a process for producing said polypeptide and for producing bacteria expressing said polypeptide. Finally, the present invention relates to a composition comprising the polynucleotide of the present invention, the vector of the present invention, the host of the present invention, the polypeptide of the present invention, the antibody of the present invention and/or one or more primers of the present invention. | 09-03-2009 |