Patent application number | Description | Published |
20100056804 | Compound containing carboxylate ester and N2S2 ligand bi-functional groups and manufacturing method thereof - A compound containing carboxylate ester and N2S2 ligand bi-functional groups and a manufacturing method thereof are disclosed. The S in the N2S2 ligand of the compound containing carboxylate ester and N2S2 ligand bi-functional groups includes a protective group so as to avoid to be oxidized and easy storage. In a complex reaction, the protective group is automatically released As to the active carboxylate ester, it is for reacting with compounds having amino groups such as amines, amino acids, peptides, or protein etc while the N2S2 ligand is for bonding with technetium or rhenium so as to form neutral complex. The compound containing carboxylate ester and N2S2 ligand bi-functional groups is applied to radiopharmaceuticals such as contrast agents for tissues and target agents. | 03-04-2010 |
20100183508 | RADIOACTIVE MIXTURE AND MANUFACTURING METHOD THEREOF - A radioactive mixture and a manufacturing method thereof are disclosed. The radioactive mixture ( | 07-22-2010 |
20110040119 | METHOD FOR PREPARING PRECURSOR OF RADIOACTIVE 3-IODOBENZYLGUANIDINE - A method for preparing a precursor of radioactive 3-iodobenzylguanidine-N,N′-bis(tert-butyloxycarbonyl)-3-(tri-n-butyltin)benzylguanidine) (MSnBG) is revealed. The MSnBG is a precursor of [*I]MIBG that is used as radioactive imaging agents and antineoplastic drugs. The method includes following steps. Firstly, obtain 3-iodobenzylguanidine bicarbonate by an addition reaction between 3-iodobenzylamine hydrochloride and cyanamide. Use di-tert-butyl dicarbonate as a protecting agent for NH group and convert 3-iodobenzylguanidine bicarbonate into N,N′-bis(tert-butyloxycarbonyl)-N-(3-iodobenzyl) guanidine. At last, under catalysis of bis(triphenylphosphine) palladium dichloride, obtain a final product MSnBG by a substitution reaction between N,N′-bis(tert-butyloxycarbonyl)-N-(3-iodobenzyl) guanidine and bis(tri-n-butyltin). MSnBG is used in no-carrier-added synthesis of [*I]MIBG. The [*I]MIBG obtained by this method has better effect on neuroblastoma treatment than that obtained by conventional, carrier-added method. | 02-17-2011 |
20110040123 | Bifunctional compound containing amino group and diaminedithiol ligand and manufacturing method thereof - A bifunctional compound containing an amino group and diaminedithiol ligand and a manufacturing method thereof are revealed, the bifunctional compound includes at least one amino group and a diaminedithiol (N | 02-17-2011 |
20110065904 | H3LMN COMPOUND USED AS RADIOACTIVE AGENT FOR TREATMENT OF LIVER CANCER AND MANUFACTURING METHOD THEREOF | 03-17-2011 |
20110313183 | METHOD FOR PREPARATION OF N-METHYL-3-(2-TRIBUTYLSTANNYLPHENOXY)-3-PHENYLPROPANAMINE, AND USE THEROF - A method for preparation of N-methyl-3-(2-tributylstannylphenoxy)-3-phenylpropanamine is provided, which includes formation of N-methyl-3-(2-tributylstannylphenoxy)-3-phenylpropanamine, useful as a precursor of a norepinephrine transporter (NET) contrast label [ | 12-22-2011 |
20120009669 | BIFUNCTIONAL COMPOUND WITH MONOSACCHARIDE AND N2S2 LIGAND, AND PREPARATION AND USE THEREOF - A bifunctional compound with a monosaccharide and a N | 01-12-2012 |
20160058649 | REHABILITATION DEVICE WITH PACE PATTERN PROJECTING FUNCTION AND SEAT STRUCTURE AND CONTROL METHOD THEREOF - A rehabilitation device with pace pattern projecting function and seat structure and a control method thereof are provided. The rehabilitation device includes a body with a moving module, a projection device, a first sensor and a control system. The projection device projects pace patterns on a walking plane. The first sensor detects a walking situation of a user on the walking plane. Based on the walking situation detected by the first sensor, the control system adjusts a distance between the rehabilitation device and the user by controlling the moving module and adjusts a position of the pace patterns on the walking plane by controlling the projection device. Moreover, a movable seat mechanism is also disposed on the rear of the rehabilitation device. The user can sit down on the movable seat mechanism and towards the front of the rehabilitation device to rest moderately. | 03-03-2016 |