Chang, Cerritos
Donald Chang, Cerritos, CA US
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20140141470 | PRODUCTION AND EXTRACTION OF MicroRNA PRECURSOR AS DRUG FOR CANCER THERAPY - This invention generally relates to a composition for developing novel anti-cancer drugs and/or vaccines and producing microRNA precursor (pre-miRNA) and/or its shRNA homologues/mimics/derivatives, and a method thereof. The present invention also relates to a use of a composition in producing novel prokaryote-produced microRNA precursor (pro-miRNA) capable of being delivered into human cells and processed by the cells into microRNA-like effectors to elicit specific silencing effects on certain targeted oncogenes, subsequently leading to a therapeutic result of tumor suppression and cancer therapy. Specifically, the method of the present invention includes inducing an expression of the pre-miRNA/pro-miRNAs, particularly human pre-miR-302, in prokaryotes through pol-2 or pol-2-like RNA promoter. Most importantly, the composition of the present invention is further a novel pre-miRNA-based drug that is capable of reprogramming the malignant properties of high-grade human liver cancers into a low-grade benign or even relatively normal stage—a mechanism called “Cancer Reversion”. | 05-22-2014 |
20150209377 | Use of Novel Monosaccharide-like Glycylated Sugar Alcohol Compositions for Designing and Developing Anti-Diabetic Drugs - This invention is related to a novel sugar-like chemical composition and its use for diabetes therapy. Particularly, the present invention teaches the use of monosaccharide-like glycylated sugar alcohol compounds to block or reduce sugar absorption in diabetes patients, so as to prevent the risk of hyperglycemia symptoms. Glycylation of sugar alcohols is a totally novel reaction that has never been reported before. Therefore, the novelty of the present invention is that for the first time glycylated sugar alcohols not only was found but also was found to be useful for treating Diabetes mellitus. In addition, the present invention teaches a method for producing these glycylated sugar alcohols. In sum, the present invention includes not only a kind of novel sugar-like chemical compositions and its use for treating diabetes but also a state-of-the-art protocol and methodology for producing such a novel composition via glycylation of sugars and sugar alcohols. | 07-30-2015 |
Eugene Chang, Cerritos, CA US
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20130067796 | Bed Bug Trap or Barrier Surrounding a Bed - A bed bug device to trap or stop bed bugs may include a substantially vertical back wall having a first layer of detachably connected adhesive to detachably attach to a bed, a top wall being connected to the vertical back wall to prevent a user from interfering with the operation of the bed bug device, a bottom wall being connected to the top wall, and a second adhesive being connected to the vertical back wall to trap the bed bugs. This bed bug device or a double sided adhesive tape or a slippery tape (one face is slippery and the other face is adhesive) may be stuck to a special mattress cover to generate an upside down rectangular prism box shaped bed bug device, so that bed bugs hiding anywhere in the bedroom may not be able to travel to the top of the bed. | 03-21-2013 |
Kenneth Chang, Cerritos, CA US
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20100145352 | HOOD METHOD AND DEVICE FOR ENDOSCOPIC SUBMUCOSAL DISSECTION - A medical device and a method of using such medical device for removing targeted tissue from a body lumen in a patient is presented. The method generally comprises placing the distal end of the device through a natural orifice in the patient to a location that is proximate to the targeted tissue; deploying a T-anchor fastened to a suture strand through the targeted tissue; deploying a loop anchor into the tissue of the body lumen spaced away from the targeted tissue, whereas the suture strand is slidably received by the loop anchor; applying tension to the suture strand; cutting the tissue at a predetermined depth around the periphery of the targeted tissue; and removing the targeted tissue along with the T-anchor from the body lumen. The tension applied to the targeted tissue maintains the targeted tissue in a raised position and/or allows the physician to manipulate the targeted tissue relative to the tissue that is proximate to it. | 06-10-2010 |
20100241197 | METHODS OF USING NITROXIDES IN CONJUNCTION WITH PHOTOSENSITIZERS AND SONOSENSITIZERS - The teachings herein relate to new methods of ameliorating the negative effects of a photosensitizer or sonosensitizer in a patient using a nitroxide. | 09-23-2010 |
20130252791 | EXTREMITY SUPPORTING AND GROUND SURFACE SLIDING EXERCISE SYSTEM - An extremity supporting exercise system is described. The system includes two knee sliders and two hand sliders. Each knee slider includes a knee pad and a knee base. The knee pad includes a recessed portion that is adapted to receive a user's knee. A patella support is disposed within the knee portion to support the user's patella when using the knee slider. Alternatively, each hand slider includes a hand pad and a hand base. The hand pad includes a series of finger indentations that are flanked by thumb receptacles. Importantly, the knee base and hand base are formed of a rigid and slippery material to allow the sliders to easily slide across a ground surface. Thus, through use of the exercise system, a user can support their hands and knees while sliding the hands and knees across a ground surface to perform a variety of exercises. | 09-26-2013 |
20150238796 | EXTREMITY SUPPORTING AND GROUND SURFACE SLIDING EXERCISE SYSTEM - An extremity supporting exercise system is described. The system includes two knee sliders and two hand sliders. Each knee slider includes a knee pad and a knee base. The knee pad includes a recessed portion that is adapted to receive a user's knee. A patella support is disposed within the knee portion to support the user's patella when using the knee slider. Alternatively, each hand slider includes a hand pad and a hand base. The hand pad includes a series of linger indentations that are flanked by thumb receptacles. Importantly, the knee base and hand base are formed of a rigid and slippery material to allow the sliders to easily slide across a ground surface. Thus, through use of the exercise system, a user can support their hands and knees while sliding the hands and knees across a ground surface to perform a variety of exercises. | 08-27-2015 |
Kenneth J. Chang, Cerritos, CA US
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20130178899 | Attachment Device for Tissue Approximation and Retraction - An attachment system for tissue apposition or manipulation and a method of attaching a suture to a tissue for apposition or manipulation of the tissue are provided. The system includes an attachment device including a body having a proximal portion and a distal portion. The attachment device further includes a tissue attachment portion operably connected to the distal portion wherein the tissue attachment portion has a shape that is maintained throughout a tissue apposition procedure. The attachment device also includes a suture operably connected to the body and having an unconnected proximal end and a retaining structure at the proximal portion of the body. The retaining structure configured to releasably mate with a complementary retaining structure on a stylet. | 07-11-2013 |