Patent application number | Description | Published |
20110142798 | HEPATITIS C VIRUS INHIBITORS - The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: | 06-16-2011 |
20110189129 | HEPATITIS C VIRUS INHIBITORS - The present invention discloses compounds of Formula (I), and pharmaceutically acceptable salts, esters, or prodrugs thereof: | 08-04-2011 |
20110300104 | HEPATITIS C VIRUS INHIBITORS - The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: | 12-08-2011 |
20120076755 | Hepatitis C Virus Inhibitors - The present invention discloses compounds of Formula (I), and pharmaceutically acceptable salts, esters, or prodrugs thereof: | 03-29-2012 |
20130262089 | NAMED ENTITY EXTRACTION FROM A BLOCK OF TEXT - A data processing method, program, and apparatus for identifying a document within a block of text. A block of text is tokenized into a plurality of text tokens according to at least one rule parser. Each of the plurality of text tokens is sequentially compared to a plurality of document tokens to determine if the text token matches one of the plurality of document tokens. The plurality of document tokens correspond to a plurality of documents which have been tokenized according to the one or more rule parsers. Each matched text token is filtered according to predetermined filtering criteria to generate one or more candidate text tokens. It is then determined whether sequence of candidate text tokens that occur in sequential order within the block of text match sequence of document tokens. If so, then it is determined that the document has been identified within the block of text. The document can correspond to an artist, a song names, and misspellings and aliases thereof. | 10-03-2013 |
20140187793 | PROCESSES FOR THE PREPARATION OF 5-AZASPIRO[2.4]HEPTANE-6-CARBOXYLIC ACID AND ITS DERIVATIVES - The present invention relates generally to an improved process for the preparation of 5-azaspiro[2.4]heptane-6-carboxylic acid and its derivatives which are useful intermediates in the synthesis of biologically active molecules, especially in the synthesis of hepatits C virus NS5A inhibitors. In particular, the present invention relates to processes and intermediates for the preparation of compounds of formulae (Ia), (Ib) and (Ic): | 07-03-2014 |
20140308243 | HEPATITIS C VIRUS INHIBITORS - The present invention discloses compounds of Formula (I), and pharmaceutically acceptable salts, esters, or prodrugs thereof: | 10-16-2014 |
20140316143 | PROCESSES FOR THE PREPARATION OF NOVEL BENZIMIDAZOLE DERIVATIVES - The present invention relates to processes and intermediates for the preparation of novel benzimidazole derivatives, especially in the synthesis of hepatitis C virus NS5A inhibitors. In particular, the present invention relates to processes and intermediates for the preparation of compounds of formulae (I-a): | 10-23-2014 |
20140341851 | NOVEL BENZIMIDAZOLE DERIVATIVES - The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: | 11-20-2014 |
20150278378 | NAMED ENTITY EXTRACTION FROM A BLOCK OF TEXT - A data processing method, program, and apparatus for identifying a document within a block of text. A block of text is tokenized into a plurality of text tokens according to at least one rule parser. Each of the plurality of text tokens is sequentially compared to a plurality of document tokens to determine if the text token matches one of the plurality of document tokens. The plurality of document tokens correspond to a plurality of documents which have been tokenized according to the one or more rule parsers. Each matched text token is filtered according to predetermined filtering criteria to generate one or more candidate text tokens. It is then determined whether sequence of candidate text tokens that occur in sequential order within the block of text match sequence of document tokens. If so, then it is determined that the document has been identified within the block of text. The document can correspond to an artist, a song names, and misspellings and aliases thereof. | 10-01-2015 |
Patent application number | Description | Published |
20090088445 | Deazapurines useful as inhibitors of Janus kinases - The present invention relates to compounds useful as inhibitors of protein kinases, particularly of JAK family kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. | 04-02-2009 |
20090176769 | CGRP RECEPTOR ANTAGONISTS - The present invention relates to CGRP receptor antagonists, pharmaceutical compositions thereof, and methods therewith for treating CGRP receptor-mediated diseases and conditions. | 07-09-2009 |
20120040950 | ISOINDOLINONE INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASE - The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3Kγ. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. | 02-16-2012 |
20120065213 | C-MET PROTEIN KINASE INHIBITORS - Described herein are compounds that are useful as ROCK inhibitors. These compounds, and pharmaceutically acceptable compositions thereof, are useful for treating or lessening the severity of a variety of disorders, including cardiovascular, inflammatory, neurological, or proliferative diseases or disorders. | 03-15-2012 |
20120165367 | AZAINDAZOLES USEFUL AS INHIBITORS OF KINASES - The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions. | 06-28-2012 |
20120202784 | ISOINDOLINONE INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASE - The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3Kγ. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. | 08-09-2012 |
20120316186 | DEAZAPURINES USEFUL AS INHIBITORS OF JANUS KINASES - The present invention relates to compounds useful as inhibitors of protein kinases, particularly of JAK family kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. | 12-13-2012 |
20130310418 | Azaindazoles useful as inhibitors of kinases - The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions. | 11-21-2013 |
20140038936 | ISOINDOLINONE INHIBITORS OF PHOSPHATIDYLINOSITOL 3-KINASE - The present invention relates to compounds useful as inhibitors of PI3K, particularly of PI3Kγ. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. | 02-06-2014 |
20140315931 | DEAZAPURINES USEFUL AS INHIBITORS OF JANUS KINASES - The present invention relates to compounds useful as inhibitors of protein kinases, particularly of JAK family kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. | 10-23-2014 |
Patent application number | Description | Published |
20110293667 | Bioengineered Tissue Constructs and Methods for Producing and Using Thereof - Bioengineered constructs are formed from cultured cells induced to synthesize and secrete endogenously produced extracellular matrix components without the requirement of exogenous matrix components or network support or scaffold members. The bioengineered constructs of the invention can be produced with multiple cell types that can all contribute to producing the extracellular matrix. Additionally or alternatively, one of the multiple cell types can be delivered to a site in the body via the endogenously produced extracellular matrix components to achieve various therapeutic benefits. | 12-01-2011 |
20130195764 | Nanoparticle Targeting to Ischemia for Imaging and Therapy - The invention provides compositions and methods that provide a solution to the difficulties in diagnosing ischemia, e.g., identifying specific affected anatomical areas, and treating ischemic tissue so as to minimize damage and promote healing of damaged tissue in a subject such as a human or other animal. | 08-01-2013 |
20130331343 | Materials Presenting Notch Signaling Molecules To Control Cell Behavior - The invention provides a solution to the problem of delivering molecules in a physiologically relevant manner to direct cell fate. For example, a Notch ligand molecule is presented in a microenvironment that mimics the environment encountered in vivo. Accordingly, the invention features a cell delivery vehicle comprising a biocompatible hydrogel or polymer and a composition that binds to a Notch receptor and methods of directing cell fate, e.g., stem cell differentiation, using such compositions. | 12-12-2013 |
20150283210 | Controlled Release Of Growth Factors And Signaling Molecules For Promoting Angiogenesis - The present invention comprises compositions, methods, and devices for delivering angiogenic factors and signaling molecules to a target tissue, and controlling the release of these factors and signaling molecules to spatially and temporally restrict their release and dissemination, for the purpose of promoting angiogenesis in target tissues wherein increased blood supply is needed. | 10-08-2015 |
Patent application number | Description | Published |
20080266245 | ELECTROPHORETIC DISPLAYS WITH CONTROLLED AMOUNTS OF PIGMENT - An electrophoretic medium has walls defining a microcavity containing an internal phase. This internal phase comprises electrophoretic particles suspended in a suspending fluid and capable of moving therethrough upon application of an electric field to the electrophoretic medium. The average height of the microcavity differs by not more than about 5 μm from the saturated particle thickness of the electrophoretic particle divided by the volume fraction of the electrophoretic particles in the internal phase. | 10-30-2008 |
20080266646 | ELECTROPHORETIC DISPLAYS WITH CONTROLLED AMOUNTS OF PIGMENT - An electrophoretic medium has walls defining a microcavity containing an internal phase. This internal phase comprises electrophoretic particles suspended in a suspending fluid and capable of moving therethrough upon application of an electric field to the electrophoretic medium. The average height of the microcavity differs by not more than about 5 μm from the saturated particle thickness of the electrophoretic particle divided by the volume fraction of the electrophoretic particles in the internal phase. | 10-30-2008 |
20090122389 | ELECTRO-OPTIC ASSEMBLIES, AND ADHESIVES AND BINDERS FOR USE THEREIN - An electro-optic assembly comprises an adhesive layer and a layer of electro-optic material. The adhesive layer comprises a polymeric adhesive material and an ionic material having either its cation or its anion fixed to the polymeric adhesive material. The ionic material reduces the volume resistivity of the polymeric adhesive material and is not removed upon heating to 50° C. In a similar electro-optic assembly comprising an adhesive layer and a layer of electro-optic material, the adhesive layer comprises a polymeric adhesive material which has been subjected to dialysis or diafiltration to remove organic species having a molecular weight less than about 3,500, so that the adhesive material has a content of N-methylpyrrolidone not exceeding 500 ppm based upon the total weight of the adhesive layer and layer of electro-optic material. | 05-14-2009 |
20090237773 | ELECTRO-OPTIC DISPLAY AND MATERIALS FOR USE THEREIN - A polyurethane formed from an isocyanate, a polyether diol and a polyester diol, the polyester diol having a molecular weight less than about 2000, or comprising two polyester diol segments connected by a steric hindrance group, each of the polyester diol segments having a molecular weight less than about 2000, the molar ratio of polyether diol to polyester diol being in the range of from about 1:9 to about 9:1. The polyurethane is useful as a lamination adhesive in electro-optic displays, and in components used to form such displays. | 09-24-2009 |
20140009817 | ELECTRO-OPTIC DISPLAYS WITH REDUCED REMNANT VOLTAGE - The invention provides materials and methods (including driving methods) for reducing the effects of remnant voltages in electro-optic displays. | 01-09-2014 |
20150221257 | ELECTRO-OPTIC DISPLAYS WITH REDUCED REMNANT VOLTAGE - The invention provides materials and methods (including driving methods) for reducing the effects of remnant voltages in electro-optic displays. | 08-06-2015 |
Patent application number | Description | Published |
20140046893 | GENERATING A TRAINING MODEL BASED ON FEEDBACK - A method and apparatus for generating a training model based on feedback are provided. The method for generating a training model based on feedback, includes calculating an eigenvector of a sample among a plurality of samples; obtaining scores granted by a user for one or more of the plurality of samples in a round, obtaining scores granted by the user for a first number of samples; obtaining scores granted by the user for a second number of samples in response to detecting, based on the eigenvector, an inconsistency between the scores granted by the user for the first number of samples; and generating a training model based on the scores granted by the user for the first and second numbers of samples. A corresponding apparatus is also provided. | 02-13-2014 |
20140161360 | Techniques for Spatial Semantic Attribute Matching for Location Identification - Techniques for spatial semantic attribute matching on image regions for location identification based on a reference dataset are provided. In one aspect, a method for matching images from heterogeneous sources is provided. The method includes the steps of: (a) parsing the images into different semantic labeled regions; (b) creating a list of potential matches by matching the images based on two or more of the images having same semantic labeled regions; and (c) pruning the list of potential matches created in step (b) by taking into consideration spatial arrangements of the semantic labeled regions in the images. | 06-12-2014 |
20140161362 | Techniques for Spatial Semantic Attribute Matching for Location Identification - Techniques for spatial semantic attribute matching on image regions for location identification based on a reference dataset are provided. In one aspect, a method for matching images from heterogeneous sources is provided. The method includes the steps of: (a) parsing the images into different semantic labeled regions; (b) creating a list of potential matches by matching the images based on two or more of the images having same semantic labeled regions; and (c) pruning the list of potential matches created in step (b) by taking into consideration spatial arrangements of the semantic labeled regions in the images. | 06-12-2014 |
20140205186 | Techniques for Ground-Level Photo Geolocation Using Digital Elevation - Techniques for generating cross-modality semantic classifiers and using those cross-modality semantic classifiers for ground level photo geo-location using digital elevation are provided. In one aspect, a method for generating cross-modality semantic classifiers is provided. The method includes the steps of: (a) using Geographic Information Service (GIS) data to label satellite images; (b) using the satellite images labeled with the GIS data as training data to generate semantic classifiers for a satellite modality; (c) using the GIS data to label Global Positioning System (GPS) tagged ground level photos; (d) using the GPS tagged ground level photos labeled with the GIS data as training data to generate semantic classifiers for a ground level photo modality, wherein the semantic classifiers for the satellite modality and the ground level photo modality are the cross-modality semantic classifiers. | 07-24-2014 |
20140205189 | Techniques for Ground-Level Photo Geolocation Using Digital Elevation - Techniques for generating cross-modality semantic classifiers and using those cross-modality semantic classifiers for ground level photo geo-location using digital elevation are provided. In one aspect, a method for generating cross-modality semantic classifiers is provided. The method includes the steps of: (a) using Geographic Information Service (GIS) data to label satellite images; (b) using the satellite images labeled with the GIS data as training data to generate semantic classifiers for a satellite modality; (c) using the GIS data to label Global Positioning System (GPS) tagged ground level photos; (d) using the GPS tagged ground level photos labeled with the GIS data as training data to generate semantic classifiers for a ground level photo modality, wherein the semantic classifiers for the satellite modality and the ground level photo modality are the cross-modality semantic classifiers. | 07-24-2014 |
20150074021 | GENERATING A TRAINING MODEL BASED ON FEEDBACK - A method and apparatus for generating a training model based on feedback are provided. The method for generating a training model based on feedback, includes calculating an eigenvector of a sample among a plurality of samples; obtaining scores granted by a user for one or more of the plurality of samples in a round, obtaining scores granted by the user for a first number of samples; obtaining scores granted by the user for a second number of samples in response to detecting, based on the eigenvector, an inconsistency between the scores granted by the user for the first number of samples; and generating a training model based on the scores granted by the user for the first and second numbers of samples. A corresponding apparatus is also provided. | 03-12-2015 |
Patent application number | Description | Published |
20110144163 | THIOLATED PACLITAXELS FOR REACTION WITH GOLD NANOPARTICLES AS DRUG DELIVERY AGENTS - Thioloated taxane derivatives are linked to colloidal metal particles such as gold nanoparticles for use as antitumor agents. The antitumor agents may be targeted to tumors. | 06-16-2011 |
20130059096 | METHODS AND COATINGS FOR TREATING BIOFILMS - A method of treating, reducing, or inhibiting biofilm formation by bacteria, the method comprising: contacting an article with a composition comprising an effective amount of a D-amino acid, said composition being essentially free of the corresponding L-amino acid, thereby treating, reducing or inhibiting formation of the biofilm, wherein the D-amino acid is selected from the group consisting of D-alanine, D-cysteine, D-aspartic acid, D-glutamic acid, D-histidine, D-isoleucine, D-lysine, D-leucine, D-asparagine, D-proline, D-glutamine, D-arginine, D-serine, D-threonine, D-valine, D-tryptophan, D-tyrosine, and a combination thereof. | 03-07-2013 |
20130071439 | METHODS AND COMPOSITIONS FOR TREATING BIOFILMS - Methods of treating or reducing biofilms, treating a biofilm-related disorder, and preventing biofilm formation using D-amino acids are described. | 03-21-2013 |
20130245130 | NATURAL PRODUCT ANTIBIOTICS AND ANALOGS THEREOF - Provided herein are pure and isolated natural products and analogs thereof of Formula (I), (II), (III), and (IV), pharmaceutical compositions thereof, and methods of use, for example, for treating a bacterial infection. Further provided are methods useful in identifying an inhibitor of bacterial sugar fermentation in a bacterial strain, such as a compound (inhibitor) of Formula (I), (II), (III), or (IV): | 09-19-2013 |
20140056951 | METHODS AND COMPOSITIONS FOR TREATING BIOFILMS - Methods of treating or reducing biofilms, treating a biofilm-related disorder, and preventing biofilm formation using polyamines is described. | 02-27-2014 |
20140056952 | METHODS AND COATINGS FOR TREATING BIOFILMS - Methods of treating or reducing biofilms, treating a biofilm-related disorder, and preventing biofilm formation using polyamines is described. | 02-27-2014 |
20140221319 | Small Molecule CD38 Inhibitors and Methods of Using Same - The invention provides methods and compositions for inhibiting CD 38 activity, and methods of treating or preventing various disorders associated with CD38 activity. | 08-07-2014 |
Patent application number | Description | Published |
20120231170 | VAPOR PERMEABLE BARRIER COATING APPLICABLE AT LOW TEMPERATURE - Disclosed is a coating composition that includes an aqueous emulsion of a hydrophobic acrylic polymer, a water-soluble polymer, and an inorganic filler, and further includes a freezing-point lowering component to permit low temperature application. The freezing-point lowering component will preferably include a water-soluble, corrosion inhibiting salt. The coating composition will also optionally and preferably include an evaporation enhancing component to promote faster drying and skin formation at low temperatures. The coating composition may be coated onto a construction surface (e.g., by spraying) where, after drying, it will form a fully adhered barrier membrane that is water-vapor permeable, but air and liquid-water impermeable. Such membrane will preferably have sufficient coating thickness and sufficiently high elongation that it will bridge joints and cracks. | 09-13-2012 |
20130008124 | Waterproofing Membrane - Disclosed is a waterproofing membrane that bonds to concrete cast against it (i.e., post-cast concrete). The membrane includes a flexible carrier sheet, a pressure sensitive adhesive and reflective particles on the surface of the adhesive. The reflective particles should have an average diameter equal to or greater than the thickness of the pressure sensitive adhesive. Preferably, the reflective particles are ground white cement, ground hydrated white cement, ground partially-hydrated white cement or a mixture of two or more of these. The membrane does not have a removable release sheet that is typically used to prevent the adhesive portion of the membrane from adhering to the carrier sheet or other portion of the membrane when the membrane is rolled up. | 01-10-2013 |
20130037989 | Waterproofing Membrane - Disclosed is a waterproofing membrane that comprises a carrier sheet, a pressure sensitive adhesive layer on one surface of the carrier sheet, and a protective coating layer on the adhesive layer. The protective coating layer comprises a highly reflective protective coating layer operative to bond to concrete cast against it, particularly one that is produced from an aqueous coating comprising an acrylic emulsion, a filler, and a white pigment. The pigment volume concentration of the filler plus white pigment is greater than or equal to 40% by volume. The protective coating layer protects the membrane against weather exposure, tolerates foot traffic and strongly adheres to concrete cast against it. The protective coating comprises an acrylic polymer with a unique multi-domain morphology (i.e., at least two distinct polymer domains). | 02-14-2013 |
20130040104 | Waterproofing Membrane - Disclosed is a waterproofing membrane that comprises a carrier sheet, a pressure sensitive adhesive layer on one surface of the carrier sheet, and a protective coating layer on the adhesive layer. The protective coating layer is highly reflective (optionally textured) and operative to bond to concrete cast against it. Preferably, the protective coating layer comprises cement, polymer, and white pigment, and may optionally or additionally include a filler, a UV absorber and an antioxidant. The protective coating layer protects the membrane against weather exposure, tolerates foot traffic and strongly adheres to concrete cast against it. Also disclosed is a waterproofing membrane comprising a carrier sheet, a pressure sensitive adhesive layer, a protective coating layer (as described above), and a highly releasable bonding layer. | 02-14-2013 |
20150052847 | WATERPROOFING MEMBRANE - Disclosed is a waterproofing membrane that comprises a carrier sheet (layer A); a waterproofing adhesive (layer B); a protective coating (layer C), wherein the protective coating is substantially free of surfactant and comprises an acrylic or methacrylic polymer or copolymer, an inorganic filler and a white pigment; and a releasable material (layer D), wherein the releasable material comprises amorphous nanoscale silica and a polymeric binder. The waterproofing membrane does not require a release liner, binds strongly to concrete cast against it (even after UV exposure), tolerates foot traffic, and withstands immersion in water over an extended period. | 02-26-2015 |
Patent application number | Description | Published |
20080263721 | Genomic plant sequences and uses thereof - The present invention discloses rice genomic promoter sequences. The promoters are particularly suited for use in rice and other cereal crops. Methods of modifying, producing, and using the promoters are also disclosed. The invention further discloses compositions, transformed host cells, transgenic plants, and seeds containing the rice genomic promoter sequences, and methods for preparing and using the same. | 10-23-2008 |
20090119022 | Emericella Nidulans Genome Sequence On Computer Readable Medium and Uses Thereof - The present invention relates to nucleic acid sequences from the filamentous fungus, | 05-07-2009 |
20110014706 | Arabidopsis thaliana Genome Sequence and Uses Thereof - The present invention relates to nucleic acid sequences from the dicotyldonus plant | 01-20-2011 |
20110185455 | Plant Genome Sequences and Uses Thereof - The present invention is in the field of plant biochemistry and genetics. More specifically the invention relates to nucleic acid sequences from plant cells, in particular, genomic DNA sequences from | 07-28-2011 |
20120096599 | Nucleic Acid Molecules and Other Molecules Associated with Plants and Uses Thereof for Plant Improvement - Recombinant polynucleotides and recombinant polypeptides useful for improvement of plants are provided. The disclosed recombinant polynucleotides and recombinant polypeptides find use in production of transgenic plants to produce plants having improved properties. | 04-19-2012 |
20120216318 | Nucleic acid molecules and other molecules associated with plants - Polynucleotides useful for improvement of plants are provided. In particular, polynucleotide sequences are provided from plant sources. Polypeptides encoded by the polynucleotide sequences are also provided. The disclosed polynucleotides and polypeptides find use in production of transgenic plants to produce plants having improved properties. | 08-23-2012 |
20130333071 | Plant Genome Sequence and Uses Thereof - The present invention is in the field of plant biochemistry and genetics. More specifically the invention relates to nucleic acid molecules from plant cells, in particular, genomic DNA sequences from rice plants and nucleic acid molecules that contain markers, in particular, single nucleotide polymorphism (SNP) and repetitive element markers. In addition, the present invention provides nucleic acid molecules having regulatory elements or encoding proteins or fragments thereof. The invention also relates to proteins and fragments of proteins so encoded and antibodies capable of binding the proteins. The invention also relates to methods of using the nucleic acid molecules, markers, repetitive elements and fragments of repetitive elements, regulatory elements, proteins and fragments of proteins, and antibodies, for example for genome mapping, gene identification and analysis, plant breeding, preparation of constructs for use in plant gene expression, and transgenic plants. | 12-12-2013 |
20140130204 | Genomic plant sequences and uses thereof - The present invention discloses rice genomic promoter sequences. The promoters are particularly suited for use in rice and other cereal crops. Methods of modifying, producing, and using the promoters are also disclosed. The invention further discloses compositions, transformed host cells, transgenic plants, and seeds containing the rice genomic promoter sequences, and methods for preparing and using the same. | 05-08-2014 |
Patent application number | Description | Published |
20140023661 | COMBINATION THERAPY - The present invention relates to a pharmaceutical combination comprising an alpha-isoform specific phosphatidylinositol 3-kinase inhibitor compound, such as (S)-Pyrrolidine-1,2-dicarboxylic acid 2-amide 1-({4-methyl-5-[2-(2,2,2-trifluoro-1,1-dimethyl-ethyl)-pyridin-4-yl]-thiazol-2-yl}-amide), or pharmaceutically acceptable salt thereof, and an IGF1R inhibitor (e.g., the IGF1R inhibitor ANTIBODY A, or a variant or derivative thereof), a pharmaceutical composition comprising such combination, methods for treating cancer comprising administration of therapeutically effective amounts of such inhibitors to a subject in need thereof, and uses of such combination for the treatment of cancer. | 01-23-2014 |
20150290204 | COMBINATION THERAPY - A pharmaceutical combination comprising (a) a compound of formula (I), | 10-15-2015 |