Patent application number | Description | Published |
20090025181 | Slow Closing Hinge Apparatus - The present invention provides a self-closing hinge suitable for use in a variety of applications where it is desirable to provide for automatic closing of a hinged member in a delayed or slow fashion. The invention includes a generally cylindrical outer casing or housing that partially encloses a rotatable shaft that may be secured to a hinged member to effect the rotation thereof. The shaft is disposed within a recess in a cylindrical coupler that is engaged by the shaft during rotation in a first direction—generally an “open” rotational direction—and that engages the shaft to rotate it in a second direction—generally a “closed” rotational direction. The coupler is secured to a torsional spring that acts against the open rotation of the shaft and thereby forces the coupler to rotate in a closed direction. Additionally, a rotatable inner casing, which is generally cylindrical, may be disposed within the outer casing in close proximity thereto, such that a high viscosity fluid may be disposed therebetween. | 01-29-2009 |
20120302408 | SINGLE BELT OMNI DIRECTIONAL TREADMILL - A treadmill having a belt assembly allows a user the walk or run in any direction. A single helically wound belt over a flattened torus is powered by two independent drive systems. The drive systems are controlled by a combination of infrared cameras and a physical harness system. | 11-29-2012 |
20130276963 | BAT FABRICATION SYSTEM AND METHOD - A bat is created using efficient and automated techniques to apply layers of composite materials onto a mandrel. The system includes a plurality of rotating wrapping mechanisms binding stages. Each wrapping mechanism rotates along a central axis while a mandrel is driven through the axis. The rotational motion allows each wrapping mechanism to wrap one or more material strips along the outer surface of the mandrel. Between each wrapping layer, a binding material such as fusible thread may be applied to fuse wrapping layers together. The wrapping may be performed for the bat barrel and bat handle. Each mandrel may form two bats, and multiple mandrels can be connected together to maximize wrapping efficiency. The wrapped mandrels are separated into bat units, a resin transfer molding is performed, and the bats are completed. | 10-24-2013 |
20130316859 | TAMPER-RESISTANT BALL BAT - A tamper-resistant ball bat may include a barrel having a tamper-resistant layer and a handle coupled to the barrel. The tamper-resistant layer may include a plurality of composite strips. The composite strips may be layered such that each composite strip radiates outward from the longitudinal axis of the barrel. Each composite strip may include a plurality of longitudinal edges. The longitudinal edges may be disposed at an angle with respect to the longitudinal axis of the barrel. | 11-28-2013 |
20140336010 | Single Belt Omni Directional Treadmill - A treadmill having a belt assembly allows a user to walk or run in any direction. A single helically wound belt over a flattened torus is powered by two independent drive systems. The drive systems are controlled by a combination of infrared cameras and a physical harness system. | 11-13-2014 |
Patent application number | Description | Published |
20090143176 | Apparatus for deterring modification of sports equipment - The present invention relates to an apparatus for playing ball sports including softball. More particularly, the present invention relates to an apparatus for deterring the modification of ball bats. The bat comprises a barrel, a sweet spot, a transition area, a handle, and an end knob. Within the barrel are found supports used to reinforce the structural integrity of the bat to deter users from crushing the bat, causing the bat to fall outside the legal classification of bats allowed by the Amateur Softball Association of America (ASA). The supports are made out of a lightweight durable composition. The supports are held in place by a retaining member. Multiple supports and retaining members may be used. | 06-04-2009 |
20110059820 | Apparatus for deterring modification of sports equipment - The present invention relates to an apparatus for playing ball sports including softball. More particularly, the present invention relates to an apparatus for deterring the modification of ball bats. The bat comprises a barrel, a sweet spot, a transition area, a handle, and an end knob. Within the barrel are found supports used to reinforce the structural integrity of the bat to deter users from crushing the bat, causing the bat to fall outside the legal classification of bats allowed by the Amateur Softball Association of America (ASA). The supports are made out of a lightweight durable composition. The supports are held in place by a retaining member. Multiple supports and retaining members may be used. | 03-10-2011 |
20110098141 | Vibration dampening ball bat - The present invention relates to a ball bat with improved shock and vibration dampening. More particularly, the present invention relates to a ball bat with a handle, a barrel, and a socket assembly interposed between the handle and barrel. The socket assembly allows the barrel and handle to move relative to each other, which dampens shock and vibration. | 04-28-2011 |
20110152015 | Ball bat with internal impact dampening means - Industry regulatory organizations have created performance restrictions for ball bats. The present invention relates to a ball bat with an internal impact dampening means. More particularly, the present invention relates to a ball bat with a handle, a barrel, and a central tube positioned coaxially within the barrel. The central tube includes at least one restriction member capable of limiting the deformation experienced by the ball bat upon impact of a ball. Precisely limiting the deformation of the ball bat allows the present invention to achieve, but not exceed, performance substantially equal to the maximum performance allowed by industry regulatory organizations and maintain that level of performance over a substantial length of the ball bat. | 06-23-2011 |
Patent application number | Description | Published |
20090268575 | Systems and Methods for Reducing Attenuation of Information Derived from a Defective Medium - Various embodiments of the present invention provide systems and methods for data regeneration. For example, a method for data regeneration is disclosed that includes receiving a data input derived from a medium, determining a media defect corresponding to the data input, and determining an attenuation factor associated with the defective medium. Based at least in part on the determination that the medium is defective, amplifying the data input by a derivative of the attenuation factor to regenerate the data. | 10-29-2009 |
20100157464 | Systems and Methods for Adaptive MRA Compensation - Various embodiments of the present invention provide systems and methods for reducing head distortion. For example, various embodiments of the present invention provide storage devices that include a storage medium, a read/write head assembly, and an adaptive distortion modification circuit. The storage medium includes information that may be sensed by the read/write head assembly that is disposed in relation to the storage medium. The adaptive distortion modification circuit receives the information sensed by the read/write head assembly and adaptively estimates and implements a distortion compensation factor in the analog domain. In some instances of the aforementioned embodiments, the read/write head assembly includes a magneto resistive head. In such instances, the distortion compensation factor is designed to compensate for non-linear distortion introduced by the magneto resistive head. | 06-24-2010 |
20100322048 | Systems and Methods for Codec Usage Control During Storage Pre-read - Various embodiments of the present invention provide systems and methods for data processing. For example, a data processing circuit is disclosed that includes an increased iteration enable signal, a first detector circuit, a second detector circuit, and a data decoding circuit. The first detector circuit receives a data set and performs a data detection on the data set to provide a detected data set. The data decoding circuit receives a derivative of the detected data set and performs a decoding process to provide a decoded data set. The decoded data set is provided to the second detector circuit based at least in part on an assertion level of the increased iteration enable signal. | 12-23-2010 |
20110242691 | Systems and Methods for Detecting Head Contact - Various embodiments of the present invention provide systems and methods for determining contact with a storage medium. As an example, a data storage system is disclosed that includes: a head assembly and a data processing circuit. The head includes a head disk interface sensor operable to provide a contact signal indicating contact between the head and a storage medium disposed in relation to the head. The data processing circuit is operable to process the contact signal to yield an indication of a contact between the storage medium and the head. | 10-06-2011 |
20120102261 | Systems and Methods for Tiered Non-Volatile Storage - Various embodiments of the present invention provide systems and methods for tiered non-volatile storage. As an example, a multi-tiered non-volatile storage device is disclosed that includes a hard disk storage; a solid state, non-volatile storage that caches a subset of data included on the hard disk storage; and a controller circuit that is operable to control data transfer between the solid state, non-volatile storage and the hard disk storage | 04-26-2012 |
Patent application number | Description | Published |
20140126287 | Methods And Apparatus For Storing Data In A Multi-Level Cell Flash Memory Device With Cross-Page Sectors, Multi-Page Coding And Per-Page Coding - Methods and apparatus are provided for storing data in a multi-level cell flash memory device with cross-page sectors, multi-page coding and per-page coding. A single sector can be stored across a plurality of pages in the flash memory device. Per-page control is provided of the number of sectors in each page, as well as the code and/or code rate used for encoding and decoding a given page, and the decoder or decoding algorithm used for decoding a given page. Multi-page and wordline level access schemes are also provided. | 05-08-2014 |
20140126288 | Methods And Apparatus For Storing Data In A Multi-Level Cell Flash Memory Device With Cross-Page Sectors, Multi-Page Coding And Per-Page Coding - Methods and apparatus are provided for storing data in a multi-level cell flash memory device with cross-page sectors, multi-page coding and per-page coding. A single sector can be stored across a plurality of pages in the flash memory device. Per-page control is provided of the number of sectors in each page, as well as the code and/or code rate used for encoding and decoding a given page, and the decoder or decoding algorithm used for decoding a given page. Multi-page and wordline level access schemes are also provided. | 05-08-2014 |
20140126289 | Methods And Apparatus For Storing Data In A Multi-Level Cell Flash Memory Device With Cross-Page Sectors, Multi-Page Coding And Per-Page Coding - Methods and apparatus are provided for storing data in a multi-level cell flash memory device with cross-page sectors, multi-page coding and per-page coding. A single sector can be stored across a plurality of pages in the flash memory device. Per-page control is provided of the number of sectors in each page, as well as the code and/or code rate used for encoding and decoding a given page, and the decoder or decoding algorithm used for decoding a given page. Multi-page and wordline level access schemes are also provided. | 05-08-2014 |
Patent application number | Description | Published |
20120242667 | BIOLOGICALLY BASED CHAMBER MATCHING - The subject disclosure relates to automatically learning relationships among a plurality of manufacturing tool parameters as applied to arbitrary semiconductor manufacturing tools and a graphical user interface that is supported, at least in part, by an autonomous learning system. The graphical user interface can create one or more matrixes based on received data and can further generate additional matrices by transforming the one or more matrixes. A series of windows can be output, wherein the series of windows, provide performance analysis that comprises a matching between a focus chamber and a reference chamber. In an aspect, the focus chamber and the reference chamber can be different chambers. In another aspect, the focus chamber and the reference chamber can be the same chamber, which provides analysis of the deterioration in performance of the same chamber over time. | 09-27-2012 |
20140304196 | BIOLOGICALLY BASED CHAMBER MATCHING - The subject disclosure relates to automatically learning relationships among a plurality of manufacturing tool parameters as applied to arbitrary semiconductor manufacturing tools and a graphical user interface that is supported, at least in part, by an autonomous learning system. The graphical user interface can create one or more matrixes based on received data and can further generate additional matrices by transforming the one or more matrixes. A series of windows can be output, wherein the series of windows, provide performance analysis that comprises a matching between a focus chamber and a reference chamber. In an aspect, the focus chamber and the reference chamber can be different chambers. In another aspect, the focus chamber and the reference chamber can be the same chamber, which provides analysis of the deterioration in performance of the same chamber over time. | 10-09-2014 |
Patent application number | Description | Published |
20080200910 | Replaceable and/or Easily Removable Needle Systems for Dermal and Transdermal Cryogenic Remodeling - The present invention generally provides improved medical devices, systems, and methods. Embodiments may be particularly well suited for the treatment of dermatological and/or cosmetic defects, and alternative embodiments may be configured for treatment of a wide range of target tissues. Some embodiments of the present invention apply cooling with at least one small, tissue-penetrating probe, the probe often comprising a needle having a size suitable for inserting through an exposed surface of the skin of a patient without leaving a visible scar. The cooling may remodel one or more target tissue so as to effect a desired change in a composition of the target tissue and/or a change in its behavior. Exemplary embodiments make use of replaceable needle probes supported by a probe body handle, with small needle probes often being replaced during treatment of a single patient. Unlike the large format cryogenic cooling systems of the past, small cryogenic cooling needle probes may dull or be damaged by insertion. Careful control over the control of cryogenic cooling fluid into a needle probe can allow the length of the active cooling to be controlled through depletion of liquid from an evaporating cryogenic cooling flow. Hence, even needles having similar external structures may provide differing lengths of an iceball along the needle axis. Surprisingly, small cryogenic cooling needles and/or other cryogenic cooling probes having a lubricious coating will allow safe removal of the probe from the treatment region while at a least a portion of the tissue remains frozen, significantly decreasing the overall time for a procedure involving many insertion/freeze/removal cycles. | 08-21-2008 |
20090248001 | Pain management using cryogenic remodeling - Medical devices, systems, and methods for pain management and other applications may apply cooling with at least one probe inserted through an exposed skin surface of skin. The cooling may remodel one or more target tissues so as to effect a desired change in composition of the target tissue and/or a change in its behavior, often to interfere with transmission of pain signals along sensory nerves. Alternative embodiments may interfere with the function of motor nerves, the function of contractile muscles, and/or some other tissue included in the contractile function chain so as to inhibit muscle contraction and thereby alleviate associated pain. In some embodiments, other sources of pain such as components of the spine (optionally including herniated disks) may be treated. | 10-01-2009 |
20120158004 | STEERABLE AND CURVABLE VERTEBROPLASTY SYSTEM WITH CLOG-RESISTANT EXIT PORTS - Methods and devices for augmenting bone, such as in performing vertebroplasty are disclosed. A bone cement injection needle is provided, having a laterally deflectable distal end. The distal end may be provided with one or two or more cavity creation elements, such as a bevel or diamond tip or inflatable balloons. A cavity creation element may include one or more filament layers. Systems are also disclosed, including the steerable and curvable injection needle, introducer and stylet. The system can also include various exit ports that can be configured with clog-resistant features. Methods are also disclosed. | 06-21-2012 |
20120191095 | STEERABLE CURVABLE VERTEBROPLASTY DRILL - Disclosed herein is a steerable and curvable drill that can be used for various applications including vertebroplasty. The drill can include an elongate, tubular body, having a proximal end, a distal end, and a central lumen extending therethrough; a deflectable zone on the distal end of the tubular body including one or more laser cuts, deflectable through an angular range; an insertable wire insertable into at least a portion of the central lumen of the elongate, tubular body; a handle on the proximal end of the tubular body; a deflection control on the handle; a drill control on the handle; a drive shaft within the elongate tubular body having a proximal end and a distal end; and a boring element on the distal end of the device for creating a cavity within bone. The boring element can be operably connected to the distal end of the drive shaft via a crimping mechanism. Systems and methods involving the drill are also disclosed. | 07-26-2012 |
20120265186 | STEERABLE CURVABLE ABLATION CATHETER FOR VERTEBROPLASTY - Disclosed herein is a steerable, curvable catheter with one, two, or more ablation elements that can be used for various applications including vertebroplasty. The catheter can include an elongate, tubular body, having a proximal end, a distal end, and a central lumen extending therethrough; a deflectable zone on the distal end of the tubular body, deflectable through an angular range; a handle on the proximal end of the tubular body; and a deflection control on the handle; an energy delivery control on the handle; and one or more energy delivery elements on the distal end of the device for ablating tissue within bone. The energy delivery elements could be RF heating electrodes in a monopole or dipole arrangement although other energy delivery modalities are also contemplated. For example, the energy delivery elements include cryoprobes. Systems and methods involving the ablation catheter are also disclosed. | 10-18-2012 |
20130218148 | Pain Management Using Cryogenic Remodeling - Medical devices, systems, and methods for pain management and other applications may apply cooling with at least one probe inserted through an exposed skin surface of skin. The cooling may remodel one or more target tissues so as to effect a desired change in composition of the target tissue and/or a change in its behavior, often to interfere with transmission of pain signals along sensory nerves. Alternative embodiments may interfere with the function of motor nerves, the function of contractile muscles, and/or some other tissue included in the contractile function chain so as to inhibit muscle contraction and thereby alleviate associated pain. In some embodiments, other sources of pain such as components of the spine (optionally including herniated disks) may be treated. | 08-22-2013 |
20130324990 | Replaceable and/or Easily Removable Needle Systems for Dermal and Transdermal Cryogenic Remodeling - The present invention generally provides improved medical devices, systems, and methods. Some embodiments of the present invention apply cooling with at least one small, tissue-penetrating probe, the probe often comprising a needle having a size suitable for inserting through an exposed surface of the skin of a patient without leaving a visible scar. The cooling may remodel one or more target tissue so as to effect a desired change in a composition of the target tissue and/or a change in its behavior. Exemplary embodiments make use of replaceable needle probes supported by a probe body handle, with small needle probes often being replaced during treatment of a single patient. Careful control over the control of cryogenic cooling fluid into a needle probe can allow the length of the active cooling to be controlled through depletion of liquid from an evaporating cryogenic cooling flow. | 12-05-2013 |
20130345709 | STEERABLE AND CURVABLE CAVITY CREATION SYSTEM - Methods and devices for augmenting bone, such as in performing vertebroplasty are disclosed. A bone cement injection needle is provided, having a laterally deflectable distal end. Systems are also disclosed, including the steerable and curvable injection needle, introducer and stylet. The system can also include various exit ports that can be configured with clog-resistant features, such as an obturator. Steerable cavity creation systems and methods are also disclosed. | 12-26-2013 |
20140249519 | PAIN MANAGEMENT USING CRYOGENIC REMODELING - Medical devices, systems, and methods for pain management and other applications may apply cooling with at least one probe inserted through an exposed skin surface of skin. The cooling may remodel one or more target tissues so as to effect a desired change in composition of the target tissue and/or a change in its behavior, often to interfere with transmission of pain signals along sensory nerves. Alternative embodiments may interfere with the function of motor nerves, the function of contractile muscles, and/or some other tissue included in the contractile function chain so as to inhibit muscle contraction and thereby alleviate associated pain. In some embodiments, other sources of pain such as components of the spine (optionally including herniated disks) may be treated. | 09-04-2014 |
20140316413 | STEERABLE CURVABLE VERTEBROPLASTY DRILL - Disclosed herein is a steerable and curvable drill that can be used for various applications including vertebroplasty. The drill can include an elongate, tubular body, having a proximal end, a distal end, and a central lumen extending therethrough; a deflectable zone on the distal end of the tubular body including one or more laser cuts, deflectable through an angular range; an insertable wire insertable into at least a portion of the central lumen of the elongate, tubular body; a handle on the proximal end of the tubular body; a deflection control on the handle; a drill control on the handle; a drive shaft within the elongate tubular body having a proximal end and a distal end; and a boring element on the distal end of the device for creating a cavity within bone. The boring element can be operably connected to the distal end of the drive shaft via a crimping mechanism. Systems and methods involving the drill are also disclosed. | 10-23-2014 |
Patent application number | Description | Published |
20090069797 | BIPOLAR DEVICES FOR MODIFICATION OF AIRWAYS BY TRANSFER OF ENERGY - This relates to a device for treating lung disease, and more particularly, relates to a device for exchanging energy with airway tissue such as that found in the airways of human lungs. The exchange of energy with this airway tissue in the airways reduces the ability of the airways to constrict and/or reduces the resistance within the airway to the flow of air through the airway. | 03-12-2009 |
20130023968 | MODIFICATION OF AIRWAYS BY APPLICATION OF ENERGY - Methods and devices for treating reversible chronic obstructive pulmonary disease are disclosed, which include a device for delivering energy to a wall of an airway in a human lung. The device includes a flexible elongate body with a proximal portion, a distal portion, a distal end, and a lumen extending therebetween. The device also includes a deployment member having an electrically conducting wire extending from the proximal portion of the elongate body and extending through the lumen and terminating at a distal tip distal to the distal end of the elongate body. The device further includes an expandable basket having a plurality of curved electrode legs and a temperature sensing element coupled to the expandable basket. | 01-24-2013 |
20130253623 | MODIFICATION OF AIRWAYS BY APPLICATION OF ENERGY - This relates to treating reversible chronic obstructive pulmonary disease, and more particularly, to exchanging energy with airway tissue such as that found in human lungs. This exchange of energy reduces the ability of the airways to constrict, reduces the resistance within the airway to the flow of air through the airway, reduces mucus plugging of the airways, and/or increases the airway diameter. This energy exchange also may reduce the ability of the lung to produce at least one of the symptoms of reversible obstructive pulmonary disease. | 09-26-2013 |
Patent application number | Description | Published |
20090327216 | Dynamic run-time optimization using automated system regulation for a parallel query optimizer - A computer-implemented apparatus, method, and article of manufacture for optimizing a database query. System conditions and operating environment events that occur during operation of the computer system are monitored. An n-dimensional optimizer matrix is used to identify at least one rule resulting from the monitored system conditions and operating environment events. An optimal query execution plan is selected from among a plurality of query execution plans generated for the query in response to the identified rule. | 12-31-2009 |
20100106708 | Eliminating unnecessary statistics collections for query optimization - A method and system for eliminating unnecessary statistics collections for query optimization in a database stored on a computer. Statistics are unnecessary when a re-generated query execution plan that does not use the statistics is equivalent to an original query execution plan that uses the statistics. To determine this, an original query execution plan is created for each query in a specified workload using the statistics in the database. A search is performed of the statistics in order to enumerate one or more candidate sets of statistics to be eliminated. One or more of the candidate sets of statistics are removed from consideration prior to creating the re-generated query execution plan for each query in the specified workload. The re-generated query execution plan, which was created with one or more of the candidate sets of statistics removed from consideration, is compared with the original query execution plan, which was created using the statistics, in order to determine whether the re-generated query execution plan and the original query execution plan are equivalent. The one or more of the candidate sets of statistics removed from consideration are identified as unnecessary when the re-generated query execution plan and the original query execution plan are equivalent. | 04-29-2010 |
20100125565 | Actively managing resource bottlenecks in a database system - A computer-implemented method, apparatus and article of manufacture for optimizing a database query. Resource usage of one or more resources of the computer system are monitored. A condition code representative of the monitored resource usage is stored. A cost model is modified using the stored condition code. A query execution plan is generated for the database query using the modified cost model. The query execution plan is then executed in order to retrieve data from a database stored on the computer system, wherein the retrieved data is presented to a user for subsequent use and analysis. | 05-20-2010 |
20120059817 | METHOD FOR INCREASING THE EFFICIENCY OF SYNCHRONIZED SCANS THROUGH INTELLIGENT QUERY DISPATCHING - A computer-implemented method, apparatus and article of manufacture for optimizing execution of database queries in a computer system. In one embodiment, the steps and functions include: generating first and second query execution plans for first and second requests, wherein the first and second query execution plans are each comprised of one or more steps that scan a specified table in a database stored on the computer system in order to retrieve data from the table; and executing the first and second query execution plans, wherein intelligent query dispatching is performed on the steps of the first and second query execution plans to ensure that the steps share the data retrieved from the table and cached in memory. | 03-08-2012 |
Patent application number | Description | Published |
20100216839 | Pim kinase inhibitors and methods of their use - The present invention relates to new compounds of Formulas I and II, their tautomers, stereoisomers and polymorphs, and pharmaceutically acceptable salts, esters, metabolites or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the inhibition of Pim kinase activity and/or the prophylaxis or treatment of cancer. | 08-26-2010 |
20110195980 | Bicyclic Kinase Inhibitors - New compounds, compositions and methods of inhibition of Provirus Integration of Maloney Kinase (PIM kinase) activity associated with tumorigenesis in a human or animal subject are provided. In certain embodiments, the compounds and compositions are effective to inhibit the activity of at least one PIM kinase. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a serine/threonine kinase- or receptor tyrosine kinase-mediated disorder, such as cancer. | 08-11-2011 |
20120202851 | PIM KINASE INHIBITORS AND METHODS OF THEIR USE - The present invention relates to new compounds of Formulas I and II, their tautomers, stereoisomers and polymorphs, and pharmaceutically acceptable salts, esters, metabolites or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the inhibition of Pim kinase activity and/or the prophylaxis or treatment of cancer. | 08-09-2012 |
20120208815 | PIM KINASE INHIBITORS AND METHODS OF THEIR USE - New compounds, compositions and methods of inhibition of kinase activity associated with tumorigenesis in a human or animal subject are provided. In certain embodiments, the compounds and compositions are effective to inhibit the activity of at least one serine/threonine kinase or receptor tyrosine kinase. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a serine/threonine kinase- or receptor tyrosine kinase-mediated disorder, such as cancer. | 08-16-2012 |
20120225061 | TETRASUBSTITUTED CYCLOHEXYL COMPOUNDS AS KINASE INHIBITORS - The present invention provides a compound of formula (I): | 09-06-2012 |
20120225062 | NOVEL KINASE INHIBITORS - The present invention provides compounds of Formula I: | 09-06-2012 |
20130109682 | CYCLIC ETHER COMPOUNDS USEFUL AS KINASE INHIBITORS | 05-02-2013 |
20130336965 | NOVEL RING-SUBSTITUTED N-PYRIDINYL AMIDES AS KINASE INHIBITORS - The present invention provides a compound of formula (A): | 12-19-2013 |
20140275003 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS - The present invention provides compounds of Formula (I) | 09-18-2014 |
20150150873 | NOVEL RING-SUBSTITUTED N-PYRIDINYL AMIDES AS KINASE INHIBITORS - The present invention provides a compound of formula (A): | 06-04-2015 |
Patent application number | Description | Published |
20100048547 | PI 3-KINASE INHIBITORS AND METHODS OF THEIR USE - Phosphatidylinositol (PI) 3-kinase inhibitor compounds, their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases, including proliferative diseases, inflammatory and obstructive airways diseases, allergic conditions, autoimmune and cardiovascular diseases. | 02-25-2010 |
20100075965 | PI3 KINASE INHIBITORS AND METHODS OF THEIR USE - Phosphatidylinositol (PI) 3 kinase inhibitor compounds, their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, phospholipid kinases, G-protein coupled receptors, and phosphatases. | 03-25-2010 |
20100249126 | PYRIMIDINE DERIVATIVES USED AS PI-3-KINASE INHIBITORS - Phosphatidylinositol (PI) 3-kinase inhibitor compounds (I), their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases. | 09-30-2010 |
20110195956 | Heterocyclic Kinase Inhibitors - New compounds, compositions and methods of inhibition of Provirus Integration of Maloney Kinase (PIM kinase) activity associated with tumorigenesis in a human or animal subject are provided. In certain embodiments, the compounds and compositions are effective to inhibit the activity of at least one PIM kinase. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a serine/threonine kinase- or receptor tyrosine kinase-mediated disorder, such as cancer. | 08-11-2011 |
20120225859 | PYRIMIDINE DERIVATIVES USED AS PI-3 KINASE INHIBITORS - Phosphatidylinositol (PI) 3-kinase inhibitor compounds (I), their pharmaceutically acceptable salts, and prodrugs thereof; compositions of the new compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier; and uses of the new compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases characterized by the abnormal activity of growth factors, protein serine/threonine kinases, and phospholipid kinases. | 09-06-2012 |
20140249135 | PIM KINASE INHIBITORS AND METHODS OF THEIR USE - New compounds, compositions and methods of inhibition of kinase activity associated with tumorigenesis in a human or animal subject are provided. In certain embodiments, the compounds and compositions are effective to inhibit the activity of at least one serine/threonine kinase or receptor tyrosine kinase. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a serine/threonine kinase- or receptor tyrosine kinase-mediated disorder, such as cancer. | 09-04-2014 |
Patent application number | Description | Published |
20100056576 | Kinase inhibitors and methods of their use - New compounds, compositions and methods of inhibition of Provirus Integration of Maloney Kinase (PIM kinase) activity associated with tumorigenesis in a human or animal subject are provided. In certain embodiments, the compounds and compositions are effective to inhibit the activity of at least one PIM kinase. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a serine/threonine kinase- or receptor tyrosine kinase-mediated disorder, such as cancer. | 03-04-2010 |
20120134987 | KINASE INHIBITORS AND METHODS OF THEIR USE - New compounds, compositions and methods of inhibition of Provirus Integration of Maloney Kinase (PIM kinase) activity associated with tumorigenesis in a human or animal subject are provided. In certain embodiments, the compounds and compositions are effective to inhibit the activity of at least one PIM kinase. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a serine/threonine kinase- or receptor tyrosine kinase-mediated disorder, such as cancer. | 05-31-2012 |
20140079693 | KINASE INHIBITORS AND METHODS OF THEIR USE - New compounds, compositions and methods of inhibition of Provirus Integration of Maloney Kinase (PIM kinase) activity associated with tumorigenesis in a human or animal subject are provided. In certain embodiments, the compounds and compositions are effective to inhibit the activity of at least one PIM kinase. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a serine/threonine kinase- or receptor tyrosine kinase-mediated disorder, such as cancer. | 03-20-2014 |
Patent application number | Description | Published |
20090319411 | PERSONAL FINANCE INTEGRATION SYSTEM AND METHOD - An integration device retrieves credit reports, and/or other financial data that is available from one or more credit sources, for consumers and extracts financial account information from the credit reports. The integration device may then format and/or translates the account information into a format that is usable by a particular consumer's personal finance software and communicates the account information to the personal finance software. Accordingly, the personal finance software is provided with information regarding each of a plurality of financial accounts that are associated with the consumer so that the account information may be populated in the personal finance software with minimal effort by the consumer. | 12-24-2009 |
20100174638 | REPORT EXISTENCE MONITORING - Certain consumers may not have a credit report and, thus, may not be able to enroll in a credit monitoring service. A credit report monitoring system requests a credit report of consumers that are attempting to enroll in a credit monitoring service. If no credit report is located for the consumer, a credit report of the consumer is automatically periodically requested by the system. When a credit report is later located, the consumer may continue with enrollment in a credit report monitoring service. In this way, the consumer is alerted of the (possibly fraudulent) creation of a credit report and is quickly able to enroll in a credit monitoring service. | 07-08-2010 |
20110087575 | PERSONAL FINANCE INTEGRATION SYSTEM AND METHOD - An integration device retrieves credit reports, and/or other financial data that is available from one or more credit sources, for consumers and extracts financial account information from the credit reports. The integration device may then format and/or translates the account information into a format that is usable by a particular consumer's personal finance software and communicates the account information to the personal finance software. Accordingly, the personal finance software is provided with information regarding each of a plurality of financial accounts that are associated with the consumer so that the account information may be populated in the personal finance software with minimal effort by the consumer. | 04-14-2011 |
20130211986 | PERSONAL FINANCE INTEGRATION SYSTEM AND METHOD - An integration device retrieves credit reports, and/or other financial data that is available from one or more credit sources, for consumers and extracts financial account information from the credit reports. The integration device may then format and/or translates the account information into a format that is usable by a particular consumer's personal finance software and communicates the account information to the personal finance software. Accordingly, the personal finance software is provided with information regarding each of a plurality of financial accounts that are associated with the consumer so that the account information may be populated in the personal finance software with minimal effort by the consumer. | 08-15-2013 |
Patent application number | Description | Published |
20150269620 | SYSTEM AND METHOD FOR VIRAL MARKETING AND MANAGEMENT - Systems, methods, and software for relatively low cost or free viral marketing management are provided. The system, method and software may be configured to receive primary user information from a primary user, wherein the primary user information may include log in information, a primary promotional code, and information related to an advertisement for the primary user, create a primary advertisement based at least in part on the received information related to the advertisement for the primary user, send the created primary advertisement, the primary promotional code, and information associated with a marketing management system to one or more prospective secondary users, receive, by the server, secondary user information from the secondary user, wherein the secondary user information may include log in information, the primary promotional code, information related to an advertisement for the primary user, present at least a portion of the primary advertisement to the secondary user, create a secondary promotional code, and secondary advertisement based at least in part on the received information related to the advertisement for the secondary user, wherein the secondary advertisement comprises at least a portion of the primary advertisement, and send the created secondary advertisement, primary or secondary promotional code, and information associated with a marketing management system to one or more subsequent users. | 09-24-2015 |