Brian Schmidt
Brian Schmidt, Perkasie, PA US
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20110077667 | SUTURE BASED TISSUE REPAIR - The present invention provides an apparatus for suture-based tissue repair, preferably for the annulus of a spinal disc, that includes a suture loop preferably pre-tied with a sliding knot, a clasp-type component that captures the ends of the suture loop, and an optional plug member that fills the tissue defect. Also disclosed is a method that places the suture loop in a full-thickness stitch encircling the tissue defect, secures the ends of the suture loop to the clasp, and cinches the suture loop to approximate the tissue without the need to tie knots. Also disclosed is a suture passer that enables a suture strand or loop to be passed through the tissue wall, captured, and retrieved. The suture passer may optionally incorporate a clasp in such an arrangement that enables a suture loop passed through the tissue wall to be captured directly by the clasp. | 03-31-2011 |
Brian Schmidt, West Chester, PA US
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20100249809 | THREADABLE KNOT SOFT TISSUE DEFECT REPAIR SYSTEM - A soft tissue defect repair system for approximating defects, such as defects in the annulus fibrosus of an intervertebral disc, includes a cannulated rod through which is disposed a suture retrieval device. A strand of suture includes a locking or ratcheting knot pre-tied around the outside of the cannulated rod and a free end that is guided in and out of the soft tissue. A knot pusher fits around the cannulated rod, which is used to push the knot off of the cannulated rod after the stitching of the tissue is accomplished. The defect is approximated by tensioning the free end. Various suturing methods or patterns are disclosed for defect approximation. | 09-30-2010 |
20110172674 | System and Methods for Minimally Invasive Spine Surgery - Methods and instruments are provided to allow access to a surgical site through a small incision while optimizing visualization of the patient anatomy. The instrumentation provide for the retraction of soft tissue, creation of a working envelope below the skin, and access to intervertebral discs and/or the surrounding bony structures for the purpose of performing various operative procedures including discectomy, laminectomy, and other spinal fixations. One set of disclosed instrumentation provides for the targeting of placement and trajectory of spinal fixation devices while reducing the number of instruments necessary needed to pass through the surgical incision. Another instrument disclosed herein allows for the compression of the intervertebral space through a very small incision. The instrument profile is minimized by using the same instrument that is used for tightening of the pedicle screws as one of the active components of the compression instrument. | 07-14-2011 |
Brian Schmidt, Rockville, MD US
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20100167379 | BACTERIA FOR HIGH EFFICIENCY CLONING - Disclosed are novel bacterial hosts that are capable of high efficiency transformation with methylated and/or unmethylated nucleic acids, and that are bacteriophage resistant. Such bacteria contain: (1) an F′ episome that confers high efficiency transformability; (2) one or more mutations that allow transformation of methylated nucleic acids; (3) one or more mutations that allow transformation with unmethylated nucleic acids; and/or (4) one or more mutations that confer resistance to bacteriophage infection. Also disclosed are methods for transforming such bacteria, and kits that contain such bacteria (e.g., that have been made competent for transformation). | 07-01-2010 |
20120015426 | BACTERIA FOR HIGH EFFICIENCY CLONING - Disclosed are novel bacterial hosts that are capable of high efficiency transformation with methylated and/or unmethylated nucleic acids, and that are bacteriophage resistant. Such bacteria contain: (1) an F′ episome that confers high efficiency transformability; (2) one or more mutations that allow transformation of methylated nucleic acids; (3) one or more mutations that allow transformation with unmethylated nucleic acids; and/or (4) one or more mutations that confer resistance to bacteriophage infection. Also disclosed are methods for transforming such bacteria, and kits that contain such bacteria (e.g., that have been made competent for transformation). | 01-19-2012 |
Brian Schmidt, Crystal Lake, IL US
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20100139115 | VALVELESS REGENERATIVE THERMAL OXIDIZER FOR TREATING CLOSED LOOP DRYER - A system for reducing organic contaminates from the condensate discharge of a closed loop industrial drying process. The system includes a dryer, a regenerative thermal oxidizer (RTO) in flow communication with the dryer, and an energy recovery unit in flow communication with the RTO. | 06-10-2010 |
Brian Schmidt, Halfmoon Bay, CA US
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20090111160 | COMPOSITIONS COMPRISING BOWMAN-BIRK PROTEASE INHIBITORS AND VARIANTS THEREOF - The present invention provides compositions and methods related to expression of protease inhibitors and variants thereof in bacterial species. The present invention further provides fusion nucleic acids, vectors, fusion polypeptides, and processes for obtaining the protease inhibitors. | 04-30-2009 |
Brian Schmidt, Snohomish, WA US
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20090094028 | SYSTEMS AND METHODS FOR MAINTENANCE KNOWLEDGE MANAGEMENT - Knowledge-based information can be captured and processed to create a library of such knowledge. A maintenance worker performing a task for an asset can record audio and/or video information during the performance, and can upload the recording to a maintenance system. The system processes the recording to produce a text file corresponding to any speech during the recording, and generates a search index allowing the text file to be searched by a user. If the task is performed in the context of a work order, for example, information from the work order can be associated with the text file so that a user can search by text search, keyword, task, or other such information. A user then can locate and access the text file and/or the corresponding recording for playback. | 04-09-2009 |
Brian Schmidt, Palo Alto, CA US
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20090048136 | KAPPA-CARRAGEENASE AND KAPPA-CARRAGEENASE-CONTAINING COMPOSITIONS - The present invention provides cleaning compositions comprising at least one carrageenase enzyme, methods for producing carrageenase enzymes in host cells, host cells comprising recombinant polynucleotides encoding at least one carrageenase, and recombinant polynucleotides encoding carrageenase. | 02-19-2009 |
Brian Schmidt, Half Moon Bay, CA US
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20080234465 | EXPRESSION IN FILAMENTOUS FUNGI OF PROTEASE INHIBITORS AND VARIANTS THEREOF - Described herein are protease inhibitors, variants thereof and methods for their production. | 09-25-2008 |
20110183401 | Kappa-Carrageenase And Kappa-Carrageenase-Containing Compositions - The present invention provides cleaning compositions comprising at least one carrageenase enzyme, methods for producing carrageenase enzymes in host cells, host cells comprising recombinant polynucleotides encoding at least one carrageenase, and recombinant polynucleotides encoding carrageenase. | 07-28-2011 |
20120014885 | Personal Care Compositions and Methods for Their Use - The present invention provides peptides and supported peptides for treating various diseases and conditions. In particularly preferred embodiments, the present invention provides compositions and methods for personal care. In some embodiments, the present invention provides compositions for use in skin and/or hair care, as well as cosmetic compositions. In alternative particularly preferred embodiments, the present invention provides peptides and supported peptides for treating diseases of the skin, such as rosacea. In some particularly preferred embodiments, the supported peptides of the present invention are anti-VEGF peptides. In alternative particularly preferred embodiments, the anti-VEGF peptides are expressed on a scaffold protein. In some most preferred embodiments, the scaffold protein comprises BBI. | 01-19-2012 |
20120258900 | DETERGENT COMPOSITIONS CONTAINING BACILLUS SUBTILIS LIPASE AND METHODS OF USE THEREOF - The present compositions and methods relate to a lipase cloned from | 10-11-2012 |
20120309063 | DETERGENT COMPOSITIONS CONTAINING GEOBACILLUS STEAROTHERMOPHILUS LIPASE AND METHODS OF USE THEREOF - The present compositions and methods relate to a lipase cloned from | 12-06-2012 |
20120315689 | SURFACTANTS THAT IMPROVE THE CLEANING OF LIPID-BASED STAINS TREATED WITH LIPASES - Described are compositions and methods relating to the removal of oily stains from fabrics and other surfaces using a lipase in combination with a selected surfactant to mediate the release of fatty acids generated by the lipase. The compositions and methods have application in, e.g., laundry cleaning and dishwashing. | 12-13-2012 |
20140193886 | SURFACTANTS THAT IMPROVE THE CLEANING OF LIPID-BASED STAINS TREATED WITH LIPASES - Described are compositions and methods relating to the removal of oily stains from fabrics and other surfaces using a lipase in combination with a selected surfactant to mediate the release of fatty acids generated by the lipase. The compositions and methods have application in, e.g., laundry cleaning and dishwashing. | 07-10-2014 |
Brian Schmidt, Bellevue, WA US
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20130023343 | AUTOMATIC MUSIC SELECTION SYSTEM - A music method includes; determining, using a processor, a status of the activity; translating, using the processor, the status into translated music descriptive data; obtaining, using the processor, a selected music piece based on the translated music descriptive data; and causing, using the processor, a music device to play the selected music piece during the activity. | 01-24-2013 |
Brian Schmidt, Pasadena, CA US
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20150051986 | System Architecture and Methods for Facilitating Client-Side Real-Time Auctions of Advertising Inventory - System architecture and methods for enabling a client-side real-time auction of advertising inventory that works in conjunction with ad serving technologies. The method according to some embodiments of the present invention comprise: (i) an end-user visiting a web page wherein multiple advertisements are displayed, (ii) for each ad unit on the page, multiple parallel requests are sent from the end-user's browser client to multiple real-time bidders who respond with a bid & advertisement for each unit, (iii) the bids are compared within the end-user's browser and the winning bid is sent to an ad serving system to be compared with other statically priced advertisements and exchange demand to determine the winning advertisements that will be displayed to the end-user and (iv) data is aggregated for each bid and price limits are set based on the aggregations. | 02-19-2015 |